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Books in Life sciences

  • Tumor Immunology and Immunotherapy – Cellular Methods Part A

    • 1st Edition
    • Volume 631
    • January 14, 2020
    • English
    Tumor Immunology and Immunotherapy – Cellular Methods Part A, Volume 631, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. New chapters include Detection of intracellular cytokine production by T cells with flow cytometry, High-throughput identification of human antigen-specific CD8+ and CD4+ T cells using soluble pMHC multimers, In vitro assays for effector T cell functions and activity of immunostimulatory antibodies, Ex vivo energetic profiling of tumor cells and T cells from mouse models and human samples, A cytofluorimetric assay to evaluate T cell polyfunctionality, and much more.

  • Gene Environment Interactions

    Nature and Nurture in the Twenty-first Century
    • 1st Edition
    • January 14, 2020
    • Moyra Smith
    • English
    Gene Environment Interactions: Nature and Nurture in the Twenty-first Century offers a rare, synergistic view of ongoing revelations in gene environment interaction studies, drawing together key themes from epigenetics, microbiomics, disease etiology, and toxicology to illuminate pathways for clinical translation and the paradigm shift towards precision medicine. Across eleven chapters, Dr. Smith discusses interactions with the environment, human adaptations to environmental stimuli, pathogen encounters across the centuries, epigenetic modulation of gene expression, transgenerational inheritance, the microbiome’s intrinsic effects on human health, and the gene-environment etiology of cardiovascular, metabolic, psychiatric, behavioral and monogenic disorders. Later chapters illuminate how our new understanding of gene environment interactions are driving advances in precision medicine and novel treatments. In addition, the book's author shares strategies to support clinical translation of these scientific findings to improve heath literacy among the general population.

  • Deep Learning Techniques for Biomedical and Health Informatics

    • 1st Edition
    • January 14, 2020
    • Basant Agarwal + 4 more
    • English
    Deep Learning Techniques for Biomedical and Health Informatics provides readers with the state-of-the-art in deep learning-based methods for biomedical and health informatics. The book covers not only the best-performing methods, it also presents implementation methods. The book includes all the prerequisite methodologies in each chapter so that new researchers and practitioners will find it very useful. Chapters go from basic methodology to advanced methods, including detailed descriptions of proposed approaches and comprehensive critical discussions on experimental results and how they are applied to Biomedical Engineering, Electronic Health Records, and medical image processing.

  • The Heparins

    Basic and Clinical Aspects
    • 1st Edition
    • January 13, 2020
    • David Green
    • English
    The Heparins: Properties and Clinical Applications brings the latest information on heparin, one of the world's most widely used drugs. The book describes the fascinating history of the discovery of this biological agent, how it was isolated and characterized, and its use for the treatment of thrombotic disorders. The structures of various heparins are illustrated, with their function as anticoagulants delineated. This comprehensive resource arms researchers and clinicians with a concise and practical source that will assist in biomedical research, medical practice, and in improving patient outcomes.

  • Data Democracy

    At the Nexus of Artificial Intelligence, Software Development, and Knowledge Engineering
    • 1st Edition
    • January 13, 2020
    • Feras A. Batarseh + 1 more
    • English
    Data Democracy: At the Nexus of Artificial Intelligence, Software Development, and Knowledge Engineering provides a manifesto to data democracy. After reading the chapters of this book, you are informed and suitably warned! You are already part of the data republic, and you (and all of us) need to ensure that our data fall in the right hands. Everything you click, buy, swipe, try, sell, drive, or fly is a data point. But who owns the data? At this point, not you! You do not even have access to most of it. The next best empire of our planet is one who owns and controls the world’s best dataset. If you consume or create data, if you are a citizen of the data republic (willingly or grudgingly), and if you are interested in making a decision or finding the truth through data-driven analysis, this book is for you. A group of experts, academics, data science researchers, and industry practitioners gathered to write this manifesto about data democracy.

  • Protein Misfolding

    • 1st Edition
    • Volume 118
    • January 13, 2020
    • Rossen Donev
    • English
    Protein Misfolding, Volume 118, covers the wide spectrum of diseases and disorders that are attributed to protein misfolding, including degenerative and neurodegenerative, cardiovascular, renal, glaucoma, cancer, cystic fibrosis, Gaucher's disease, and many others. Specific chapters cover Mass spectrometric approaches for profiling protein folding and stability, Biomembranes, a key player in protein misfolding, how Genetic and environmental factors interact to disrupt proteostasis and trigger protein misfolding diseases, Formation of oligomers and large amorphous aggregates by intrinsically disordered proteins, Protein misfolding in ER stress with applications to cardiovascular and renal disease, and much more.

  • Latex, Laticifers and Their Molecular Components: From Functions to Possible Applications

    • 1st Edition
    • Volume 93
    • January 11, 2020
    • English
    Latex, Laticifers And Their Products, Volume 93 in the Advances in Botanical Research series, highlights new advances in the growing field of the latex of different plant species and a diversity of molecules produced by the plants within laticifers. The new volume presents timely chapters on the latest developments in Plant latex and latex-borne defense, Physiology and structure of laticifers, Low-molecular compounds of latex-bearing plants/Latex-based defense strategies against pests, Plant latex proteins and their functions, Latex and Laticifers as a Source of Useful Bioactive Compounds. Pharmacologically active compounds from latex of medicinal plants. Euphorbia latex biochemistry/ proteins, and more.

  • Nanopharmaceuticals

    Volume 1: Expectations and Realities of Multifunctional Drug Delivery Systems
    • 1st Edition
    • January 10, 2020
    • Ranjita Shegokar
    • English
    Nanopharmaceuticals reviews advances in the drug delivery field via nanovehicles or nanocarriers that offer benefits like targeted therapy and serves as a single dose magic bullet for multiple drug delivery with improved drug efficiency at a lower dose, transportation of the drug across physiological barriers as well as reduced drug-related toxicity. The chapters are written by a diverse group of international researchers from industry and academia. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems. Other volumes in the Expectations and Realities of Multifunctional Drug Delivery Systems book series: Delivery of Drugs, Volume 2, 9780128177761 Drug Delivery Trends, Volume 3, 9780128178706 Drug Delivery Aspects, Volume 4, 9780128212226

  • Genetically Modified and Irradiated Food

    Controversial Issues: Facts versus Perceptions
    • 1st Edition
    • January 9, 2020
    • Veslemøy Andersen
    • English
    Genetically Modified and Irradiated Food: Controversial Issues: Facts versus Perceptions explains the technologies used in these processes so they can be understood by those in general public health, scientific organizations, politicians and opinion makers/policymakers. The facts presented include a massive amount of scientific evidence that these technologies are safe and can be beneficial. Because the world is facing a future with an increasing number of people, new technologies are needed to ensure enough safe and healthy food, thus technologies that have the potential to dramatically increase the availability of safe and healthy food should be welcomed by everybody.

  • Agricultural Internet of Things and Decision Support for Precision Smart Farming

    • 1st Edition
    • January 9, 2020
    • Annamaria Castrignanò + 5 more
    • English
    Agricultural Internet of Things and Decision Support for Smart Farming reveals how a set of key enabling technologies (KET) related to agronomic management, remote and proximal sensing, data mining, decision-making and automation can be efficiently integrated in one system. Chapters cover how KETs enable real-time monitoring of soil conditions, determine real-time, site-specific requirements of crop systems, help develop a decision support system (DSS) aimed at maximizing the efficient use of resources, and provide planning for agronomic inputs differentiated in time and space. This book is ideal for researchers, academics, post-graduate students and practitioners who want to embrace new agricultural technologies.

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