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4271-4280 of 14737 results in All results

Stem Cells and Cancer in Hepatology

  • 1st Edition
  • May 18, 2018
  • Yun-Wen Zheng
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 2 3 0 1 - 0
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 2 3 0 2 - 7
Stem Cells and Cancer in Hepatology: From the Essentials to Application offers basic scientists and clinicians in the fields of stem cells, hepatology and oncology an overview of the interaction between liver biology, stem cells and cancer. It discusses how the liver performs regeneration and repair, the role stem cells play in these processes, and the mechanisms by which liver cancers are initiated and developed. As the field of stem cells and cancer stem cells in hepatology is new and dynamic, thus making it difficult for researchers and clinicians to understand the most relevant historic and novel studies, this volume addresses that challenge.

Heterogeneity of Function in Numerical Cognition

  • 1st Edition
  • May 17, 2018
  • Avishai Henik + 1 more
  • English
  • Hardback
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  • eBook
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Heterogeneity of Function in Numerical Cognition presents the latest updates on ongoing research and discussions regarding numerical cognition. With great individual differences in the development or function of numerical cognition at neuroanatomical, neuropsychological, behavioral, and interactional levels, these issues are important for the achievement of a comprehensive understanding of numerical cognition, hence its brain basis, development, breakdown in brain-injured individuals, and failures to master mathematical skills. These functions are essential for the proper development of numerical cognition.

Marine Enzymes and Specialized Metabolism - Part A

  • 1st Edition
  • Volume 604
  • May 17, 2018
  • Bradley S. Moore
  • English
  • Hardback
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  • eBook
    9 7 8 - 0 - 1 2 - 8 1 3 9 6 0 - 8
Marine enzymes and specialized metabolism - Part A, Volume 604 highlights experimental methods on diverse marine enzymes involved in the construction of bioactive natural product molecules. These detailed protocols are written by experts who actively study and apply marine enzymes in biosynthesis and biotechnology. Comprehensive chapters in this latest release cover Chemoenzymatic synthesis of starting materials and characterization of halogenases requiring acyl carrier protein tethered substrates, Assaying biradical aryl coupling activity of CYP450 enzymes, the Characterization and application of marine microbial omega-3 polyunsaturated fatty acid synthesis, Catalase-related allene oxide synthase: on a biosynthetic route to fatty acid cyclopentenones, Haloalkane dehalogenases from marine microorganisms, and more.

Emerging Nanotechnologies in Immunology

  • 1st Edition
  • May 17, 2018
  • Ranjita Shegokar + 1 more
  • English
  • Hardback
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  • eBook
    9 7 8 - 0 - 3 2 3 - 4 0 1 1 3 - 5
Emerging Nanotechnologies in Immunology aims to deliver a systematic and comprehensive review of data concerning the nature of interaction and nano-related risks between the nanophamaceuticals currently in the pipeline of S&T development for skin, ocular, and nasal drug delivery, including absorption, toxicity, and the ability to distribute after systemic exposure.The scientific development of manufactured nanomaterials for drug delivery is increasing rapidly. One of the most prominent applications is topical drug delivery, where cutaneous, ocular, and nasal exposure becomes even more relevant. These targets are the first barrier that nanoparticles encounter when in contact with the human body.The contributors addresses a representative set of the broad spectrum of nanopharmaceuticals currently being used, including cationic lipid nanoparticles, polymeric PLGA, PLA nanoparticles, biomacromolecules-based nanoparticles, and other scaffolds tissue engineered skin substitutes. Regulation and risk is also covered, since the safety of these nanophamaceuticals still represents a barrier to their wide innovative use.

The Arts and The Brain

  • 1st Edition
  • Volume 237
  • May 16, 2018
  • Julia F. Christensen + 1 more
  • English
  • Hardback
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  • eBook
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The Arts and the Brain: Psychology and Physiology beyond Pleasure, Volume 237, combines the work of an excellent group of experts who explain evidence on the neural and biobehavioral science of the arts. Topics covered include the emergence of early art and the evolution of human culture, the interaction between cultural and biological evolutionary processes in generating artistic creation, the nature of the aesthetic experience of art, the arts as a multisensory experience, new insights from the neuroscience of dance, a systematic review of the biological impact of music, and more.

Nitric Oxide and Other Small Signalling Molecules

  • 1st Edition
  • Volume 72
  • May 16, 2018
  • Robert K. Poole
  • English
  • Hardback
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  • eBook
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Nitric Oxide and Other Small Signalling Molecules, Volume 72, the latest release in the Advances in Microbial Physiology series, continues the long tradition of topical, important, cutting-edge reviews in microbiology. The book contains updates in the field, with comprehensive chapters covering the Biochemistry of cysteine persulfides, NO signaling in yeast, The Inflammasome: Regulation of Nitric Oxide and Antimicrobial Host Defense, Nitric Oxide, aN Old molecule with NOble functions in Pseudomonas aeruginosa biology, the Emerging roles of nitric oxide synthase in bacterial physiology, and Anaerobic bacterial response to nitrosative stress.

Cushing’s Syndrome, An Issue of Endocrinology and Metabolism Clinics of North America

  • 1st Edition
  • Volume 47-2
  • May 16, 2018
  • Adriana G. Ioachimescu
  • English
  • Hardback
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This issue of Endocrinology and Metabolism Clinics, edited by Adriana G. Ioachimescu, will focus on Cushing’s Syndrome. Topics include--but are not limited to--1. Diagnosis of Cushing’s syndrome in the modern era, Gene mutations in patients with Cushing’s syndrome, Morbidity in Cushing’s syndrome and impact of treatment, Localization of ACTH-dependent Cushing’s syndrome, Prognostic factors of long-term remission after surgical treatment of Cushing’s disease, Outcomes of pituitary radiation for Cushing’s disease, New molecular targets in Cushing’s disease, Recent advances in subclinical Cushing’s syndrome, Adrenal surgery for Cushing’s syndrome, Adrenocortical carcinoma with hypercortisolism, Ectopic Cushing’s syndrome, Medical therapy for Cushing’s syndrome in the 21st century, Pregnancy in patients with Cushing’s syndrome, Mortality in patients with Cushing’s syndrome, and Cushing’s syndrome in children and adolescents.

Butterfly Wing Patterns and Mimicry

  • 1st Edition
  • Volume 54
  • May 15, 2018
  • Richard ffrench-Constant
  • English
  • Hardback
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  • eBook
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Butterfly Wing Patterns and Mimicry, Volume 54, provides an essential reference for those interested in molecular Entomology and the study of natural selection. The volume spans work on the genetics of polymorphism in Heliconius butterflies through to a detailed analysis of the role of CRISPR-CAS in dissecting wing patterning. The volume covers both the evolution and fine scale development of both pattern and pigmentation. The role of wing shape is also considered for the first time in a formal analysis. It should be of interest to both experts and students interested in Entomology and its application to fundamental questions in evolution.

G Protein-Coupled Receptors: Emerging Paradigms in Activation, Signaling and Regulation Part B

  • 1st Edition
  • Volume 339
  • May 15, 2018
  • Arun K. Shukla
  • English
  • Hardback
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  • eBook
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International Review of Cell and Molecular Biology reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. The articles published in IRCMB have a high impact and an average cited half-life of 9 years. This great resource ranks high amongst scientific journals dealing with cell biology.

Accelerated Predictive Stability (APS)

  • 1st Edition
  • May 14, 2018
  • Fenghe Qiu + 1 more
  • English
  • Hardback
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  • eBook
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Accelerated Predictive Stability (APS): Fundamentals and Pharmaceutical Industry Practices provides coverage of both the fundamental principles and pharmaceutical industry applications of the APS approach. Fundamental chapters explain the scientific basis of the APS approach, while case study chapters from many innovative pharmaceutical companies provide a thorough overview of the current status of APS applications in the pharmaceutical industry. In addition, up-to-date experiences in utilizing APS data for regulatory submissions in many regions and countries highlight the potential of APS in support of registration stability testing for certain regulatory submissions. This book provides high level strategies for the successful implementation of APS in a pharmaceutical company. It offers scientists and regulators a comprehensive resource on how the pharmaceutical industry can enhance their understanding of a product’s stability and predict drug expiry more accurately and quickly.

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