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Books in Life sciences

  • Innovations in the Blue Economy

    Sustainable Practices in Marine Macro- and Microalgae Cultivation
    • 1st Edition
    • José Carlos Magalhães Pires
    • English
    Innovations in the Blue Economy: Sustainable Practices in Marine Macro- and Microalgae Cultivation explores the latest technologies, advancements, and ongoing research surrounding the sustainable cultivation of microalgae and seaweed. Cultivation strategies, challenges, applications, products, and regulatory considerations are covered through an interdisciplinary lens to provide readers with a holistic understanding. Written by a globally diverse network of experts, the book is systematically structured to be accessible to readers across multiple sectors. Chapters describe the biology, diversity, and vital ecological roles of various microalgal and seaweed species and explore differing cultivation systems, emphasizing the critical aspects of site selection and ecosystem compatibility. Cultivation strategies are also described and illustrated through applied case studies that showcase successful large-scale cultivation initiatives. Final chapters consider regulatory landscapes and multifaceted hurdles to sustainable industry scale-up and provide innovative solutions and research gaps for industry consideration. This is an essential read for algal aquaculturists, bioengineers, and students of marine biology and biotechnology.

  • Cutting-Edge Technology for Plant Metabolite Profiling in Drug Discovery and Quality Control

    • 1st Edition
    • Ramesh Kumar Ahirwar + 4 more
    • English
    Cutting-Edge Technology for Plant Metabolite Profiling in Drug Discovery and Quality Control offers a comprehensive exploration of advanced methods in plant metabolomics, along with their integration in industrial applications across various sectors. The book delves into a range of methodologies, including metabolic engineering strategies, metabolite imaging techniques, nuclear magnetic resonance (NMR) for plant metabolite analysis, microfluidics for metabolite profiling, computational methods, and bioinformatics tools. It also explores plant metabolomics for crop improvement, pharmaceutical development, archaeological examinations, cosmetic formulations, and food quality, with case studies featured throughout the book to showcase real-world applications and scenarios. As the demand for natural products and plant-derived therapeutics continues to rise, there is a need for reliable and effective methods to identify, quantify, and optimize the bioactive compounds present in plants. This book provides a comprehensive guide to the latest advances in this field while also delivering a multidisciplinary overview of the wide-ranging impact plant metabolites have across a variety of applications. Researchers working with plant metabolites across molecular and cellular biology, pharmaceutical science, biotechnology, biochemistry and plant science will benefit from this book. Additionally, it will be of interest to specialists working across relevant industries, such as pharmaceuticals, nutraceuticals, cosmetics and agriculture.

  • Explainable AI in Clinical Practice

    Methods, Applications, and Implementation
    • 1st Edition
    • Arvind Panwar + 4 more
    • English
    Explainable AI in Clinical Practice: Methods, Applications, and Implementation bridges the gap between artificial intelligence capabilities and their practical implementation in healthcare. The book explores applications of explainable AI in diagnostic support and treatment planning, offering insights into making AI systems interpretable and accountable. Through real-world case studies and ethical frameworks, readers learn to transform opaque AI systems into tools that enhance clinical practice while maintaining high patient care standards. This volume unites leading experts to provide a comprehensive framework for implementing explainable AI, ensuring that AI-driven decisions are transparent, trustworthy, and clinically sound. Targeted solutions in the book cater to diverse stakeholders in the healthcare AI ecosystem. Healthcare professionals will gain confidence in integrating AI tools, while technical teams will receive implementation guidelines. This book is essential for anyone seeking to responsibly and effectively navigate the complexities of AI in healthcare.

  • Chalcones

    From Drug Discovery to Pharmaceutical Applications
    • 1st Edition
    • Simone Carradori + 2 more
    • English
    Chalcones: From Drug Discovery to Pharmaceutical Applications serves as a comprehensive reference on chalcones, detailing their natural occurrence, synthetic methods, and therapeutic applications. The book provides both novice and experienced researchers with the foundational knowledge necessary to advance their work in this area. Sections cover the natural sources of chalcones, various extraction methods, structural characterization techniques, synthesis, and their role in organic chemistry and metal complexes, while also addressing pharmacokinetic properties, toxicity, and the medicinal uses of chalcones, including their effectiveness against viruses, bacteria, cancer, and neurodegenerative diseases. Final sections explore chalcone-containing products, drug formulation strategies, and clinical trials involving chalcone-based drug candidates. This reference is an essential resource for pharmaceutical researchers, providing critical insights into the applications and potential of chalcones in drug development and therapeutic interventions.

  • Cerebellum Development and Disease

    • 1st Edition
    • Volume 167
    • English
    Cerebellum Development and Disease, Volume 167 offers a comprehensive overview of the intricate processes underlying the formation, maturation, and function of the cerebellum, as well as the wide spectrum of disorders that can affect this essential brain region. Chapters in this new release cover Olivocerebellar circuit development as a substrate for dystonia pathogenesis, Simply complex – that structure of the cerebellar neuronal lineage, Ontogenesis and diversification of cerebellar glia: a developmental perspective, Purkinje cell diversification: a blueprint for cerebellar development, patterning, and evolution, On the Emergence of Folding in the Cerebellum, Scaling and regeneration in the developing cerebellum, ASTN2 in ASD and Neurodevelopmental Disorders, and much more.Additional sections focus on Stem cell-derived in vitro models of human cerebellar development, Development of Spinocerebellar System within the Precerebellar Network, and Cerebellum evo-devo. The book brings together leading experts in neurodevelopment, neurobiology, genetics, and clinical neurosciences to explore the molecular and cellular mechanisms guiding cerebellar development, from embryogenesis to adulthood.

  • Sports Medicine and the Pelvic Floor

    Science to Practice
    • 1st Edition
    • Gráinne M. Donnelly
    • English
    Sports Medicine and the Pelvic Floor: Science to Practice shines a spotlight on a critical but often overlooked aspect of female athlete health: the pelvic floor. Bringing together the expertise of international clinicians and researchers, this book highlights persistent gaps in knowledge and practice, offering valuable direction for future research. It educates professionals on how to effectively screen, treat, and rehabilitate athletes, emphasizing that pelvic floor dysfunction can profoundly impact engagement, athletic performance, and overall well-being. By addressing this traditionally taboo subject, the authors provide evidence-based insights that call for the pelvic floor to be considered as essential in sports medicine.Sections discuss practical strategies for screening and supporting athletes, managing or alleviating symptoms, and ensuring a safe return to sport, all while prioritizing long-term pelvic health. This is an indispensable resource for anyone working with female athletes, blending science and clinical experience to advance care in this vital area.

  • Structural Study of Amyloid-β

    • 1st Edition
    • Volume 729
    • English
    Structural Study of Amyloid-β, Volume 729 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on important topics such as the Extraction of Amyloids from Neurodegenerative Disease Tissues for Structural Analysis, Cryo-EM Structure Determination of Amyloid Fibrils: Methodology, Insights, and Practical Tools, Methods for studying molecular architecture of Ab aggregates in tissues using cryo-ET, Cryo-EM methods to study binding between amyloid fibrils and chemical compounds or ligan, Dynamics studies of side-chains and hydration shells in amyloid-beta fibrils using deuterium and oxygen-17 solid-state NMR, and much more.Additional chapters cover the Technical aspects of pressure jump NMR applied to the study of Abeta and protein oligomerization, Characterizations of the beta-amyloid-membran... interaction intermediates, Time-resolved solid-state NMR studies of oligomer formation, Methods for characterizing the individual filament structures of amyloid peptide assemblies using atomic force microscopy, Single-molecule fluorescence spectroscopy and imaging on heterogeneous amyloid beta aggregation, Two-dimensional FT-IR methods on amyloid aggregation and folding pathways, and much more.

  • Medical Device Design

    Innovation from Concept to Market
    • 3rd Edition
    • Peter J. Ogrodnik
    • English
    Medical Device Design: Innovation from Concept to Market, Third Edition provides the bridge between engineering design and medical device development. The book clearly explains the process of medical device development - from very early stages of conceptualization to commercialization on the global market. It addresses medical devices' regulatory (FDA and EU) requirements, shows the essential methodologies medical designers must understand to ensure their products meet requirements, and brings together proven design protocols, enabling engineers and medical device manufacturers to rapidly bring new products to the marketplace.This book is suitable for professional engineers, both new and experienced, as well as students taking a course in medical device design.

  • The Gut Microbiome in Precision Medicine

    From Research to Clinical Practice
    • 1st Edition
    • S Rehan Ahmad
    • English
    The Gut Microbiome in Precision Medicine: From Research to Clinical Practice explores the significant role of the gut microbiome in health and disease, particularly within gastrointestinal conditions such as inflammatory bowel disease, irritable bowel syndrome, and colorectal cancer. It covers how understanding and analyzing the gut microbiome can lead to personalized treatments, dietary plans, and precision medicine approaches in gastroenterology. Chapters explore multi-omics integration, examining complex techniques for gut microbiome profiling, including genomics, transcriptomics, proteomics, and metabolomics. Users will find updates on microbiome-based interventions, such as probiotics, prebiotics, and personalized nutrition that highlight practical applications in gastrointestinal disease management. Real-world examples and case studies discuss strategies for overcoming barriers to implementing microbiome analysis. Additionally, it addresses the challenges and opportunities of implementing microbiome analysis in clinical practice, with a special emphasis on its implications for developing countries. Finally, the book covers emerging technologies in microbiome research and their applications in gastroenterology, emphasizing future directions and research priorities.

  • Behavioral Biometrics and Artificial Intelligence for Neurodegenerative Diseases Assessment

    • 1st Edition
    • Vincenzo Dentamaro + 2 more
    • English
    Behavioral Biometrics and Artificial Intelligence for Neurodegenerative Diseases Assessment explores cutting-edge, non-invasive techniques for the early detection of neurodegenerative diseases. The book focuses on behavioral biometrics, which analyzes patterns in a person’s actions rather than directly measurable traits. By utilizing artificial intelligence methods—like machine learning and deep neural networks—it enables the observation of subtle changes in gait, handwriting, and speech. These advanced approaches offer promise for earlier and more accurate diagnosis, potentially improving outcomes for millions affected by conditions such as Alzheimer’s and Parkinson’s diseases through timely intervention and personalized care.In addition to its core coverage, the book delves into the practical applications of wearable sensors and the use of everyday devices like smartphones and tablets in assessments. It provides comprehensive chapters on how these technologies can aid clinicians and researchers in monitoring disease progression outside traditional clinical settings.

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