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Elsevier

Books in Life sciences

  • Gender Affirming Vaginoplasty

    • 1st Edition
    • Gennaro Selvaggi + 1 more
    • English
    Gender Affirming Vaginoplasty is a novel reference of the latest research on those who present with Gender Dysphoria and desire surgery. The book describes the history of Gender Affirming Vaginoplasty (GAV), including social, legal, and ethical aspects of GAV, and explains updated Standards of Care. Users will find sections on preparation for surgery, different surgical techniques available (inclusive with the most recent developments), surgical results and complications, ways to solve complications, and finally, surgical procedures for persons who are requesting nonbinary genital surgery, and for those who are requesting reversal surgery.This is an unprecedented resource for all surgeons from various specialties already involved in gender-affirmative surgery and colleagues interested to gain state-of-the-art knowledge and experience in this field included plastic surgeons, urologists and gynecologists. Gender centers and trainees, scientists, researchers in transgender health, and organizations involved in trans health.

  • Stress and The Brain: Evidence from Molecular Mechanisms to Interventions and Therapies

    • 1st Edition
    • Volume 291
    • English
    Stress and The Brain: Evidence from Molecular Mechanisms to Interventions and Therapies is a comprehensive exploration of how stress affects the brain at a molecular level and its broader implications for mental and neurological health. The book delves into the mechanisms by which stress triggers changes in brain function, including the activation of the hypothalamic-pituita... (HPA) axis, synaptic plasticity alterations, oxidative stress, neuroinflammation, and mitochondrial dysfunction. It examines how these molecular processes contribute to conditions such as neurodegeneration, anxiety, depression, and other stress-related disorders. Furthermore, the book provides an in-depth analysis of current therapeutic interventions, both pharmacological and behavioral, as well as natural antidotes that aim to mitigate the adverse effects of stress on the brain. By synthesizing evidence from cutting-edge research, this book offers valuable insights for scientists, clinicians, and mental health professionals seeking to understand and address the complex interplay between stress and brain health.

  • Atlas of Marine Invertebrate Larvae

    • 2nd Edition
    • Michael J. Boyle + 2 more
    • English
    Atlas of Marine Invertebrate Larvae, Second Edition covers the origins and history of marine larval science, contemporary state-of-the-art approaches to larval development and biology, and the highest-quality images and schematics showing the broadest diversity of marine larvae in the animal tree of life. This book illustrates larval body plans, the anatomy of their organ systems (muscular, sensory, digestive), including distinct ciliation patterns that facilitate swimming, and the complex metamorphic changes they undergo between different larval and growth stages. Each chapter contains in-text references that direct readers to both historical and contemporary research on the forms, functions, behaviors and biogeographical distributions of marine larvae.This book is a valuable and foundational resource for biologists across various disciplines, including biodiversity, biogeography, and developmental biology. Ecologists, taxonomists, oceanographers, and environmental scientists also benefit from the complete coverage of marine larval forms offered by this book. Additionally, the broad scope and phyletic coverage of marine biodiversity presented in this atlas is ideal for students in oceanography and marine biology, animal development, biological oceanography and invertebrate zoology.

  • Tumor-Targeting with Stimuli-Responsive Vesicular Nanocarriers

    Basics to Emerging Applications
    • 1st Edition
    • Ankit Jain + 2 more
    • English
    Tumour-Targeting with Stimuli Responsive Vesicular Nanocarriers: Basics to Emerging Applications not only acquaints scientists and science interns with the fundamental knowledge of the experimental aspects and state-of-the-art technology for vesicular carriers to equip their rational application in tumor targeting, but also provides a holistic understanding of regulatory concerns, patents, and clinical trials. In 15 chapters. this book provides basics and advances in stimuli-responsive vesicular carriers for tumor targeting based on findings outlined in highly organized tables, illustrative figures, and flow charts.With a focus on the extrapolation of bioengineering tools in the domain of vesicular carriers, stimuli-responsive features concerning tumors, drug delivery approaches, and associated challenges, it helps readers to define the major gaps in knowledge that can lead to significant scientific discoveries in therapy, diagnosis, and theragnosis of cancer.

  • The Potential of Cancer Biomarkers

    From Discovery to Clinical Application
    • 1st Edition
    • Pranav Kumar Prabhakar
    • English
    The Potential of Biomarkers: From Discovery to Clinical Application addresses the challenges related to knowledge dissemination, interdisciplinary understanding, diagnostic complexity, quality assurance, patient care, research advancement, education, and professional development within the field of clinical biochemistry. The book provides a holistic solution by offering comprehensive insights and practical guidance to a diverse audience, contributing to the enhancement of healthcare and biomedical research. Each chapter explores the multifaceted landscape of biomarker research, offering a wealth of insights and expertise in genomics, proteomics, metabolomics, and more.Cancer biomarkers, the molecular signatures of cancer, hold immense promise in revolutionizing how we diagnose, treat, and personalize therapies for cancer patients. In this curated reference, esteemed contributors explore the multifaceted landscape of biomarker research, offering a wealth of insights and expertise in genomics, proteomics, metabolomics, and more.

  • Terrestrial Biomes

    Global Biome Conservation and Global Warming Impacts on Ecology and Biodiversity
    • 1st Edition
    • Germano Leão Demolin-Leite
    • English
    Terrestrial Biomes: Global Biome Conservation and Global Warming Impacts on Ecology and Biodiversity explores the effects of anthropogenic activities on Earth’s terrestrial biomes, species, and climate. The book summarizes operational and potential monitoring tools to conserve or recover terrestrial biomes at a global scale. Written by international experts in ecology and biodiversity conservation, this book identifies the challenges and threats to terrestrial organisms and connects them to real cases of conservation.This is an important resource for students, professors, researchers, and governmental and non-governmental organizations active in biodiversity conservation and climate change mitigation.

  • Imaging of Neurofluids, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 35-2
    • Nivedita Agarwal + 1 more
    • English
    In this issue of Neuroimaging Clinics, guest editors Drs. Nivedita Agarwal and Anja van der Kolk bring their considerable expertise to the topic of Imaging of Neurofluids. Top experts discuss key topics in this burgeoning field to create a primer ideal for neuroradiologists and radiologists. Topics include the basics of neurofluids, animal models, gadolinium-based imaging, perfusion-based imaging, diffusion tensor imaging, PET imaging, and specific articles on perivascular spaces, parasagittal dura mater and meningeal lymphatics, amyloid-related imaging abnormalities, and Alzheimer’s disease.

  • Emerging Fuzzy Intelligent Systems for Smart Healthcare Management

    Applications of Disc q-Rung Orthopair Fuzzy Sets
    • 1st Edition
    • Shahzaib Ashraf + 3 more
    • English
    Emerging Fuzzy Intelligent Systems for Smart Healthcare Management: Applications of Disc q-Rung Orthopair Fuzzy Sets presents comprehensive methodological frameworks and the latest empirical research findings concerning disc q-rung orthopair fuzzy operators, with a specific focus on their applications in smart technologies for healthcare management. The book solves a crucial problem by offering readers an invaluable opportunity to conduct a comparative analysis, contrasting the proposed methods with their existing knowledge base. Disc q-Rung Orthopair sets, being the generalization of q-Rung Orthopair fuzzy sets, which are, in turn, the generalization of Pythagorean fuzzy sets, extend the capabilities of handling uncertainty beyond conventional fuzzy sets.The authors strive to narrow the knowledge gap by clarifying the practical applications of disc q-rung orthopair fuzzy logic. In addition, it explores an enhanced version of q-Rung Orthopair Fuzzy Sets, specifically focusing on Disc q-Rung Orthopair Fuzzy Sets, introducing various types of operators. These operators play a crucial role in solving decision-making and optimization problems. A notable contribution is the development of a hybrid operator, termed as the Disc q-Rung Orthopair Fuzzy Hybrid Weighted Averaging/Geometric (D-qROFHWA/G) operator.

  • Adenoviral Vectors for Gene Therapy

    • 3rd Edition
    • David T. Curiel + 1 more
    • English
    Adenoviral Vectors for Gene Therapy, Third Edition, provides detailed, comprehensive coverage of gene delivery vehicles based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, as platforms for gene therapy and gene editing, as well as for oncology approaches, making them class leading agents in the gene-advanced therapies arena.The fully updated and expanded third edition covers the basic biology of adenoviruses and highlights the potential use of adenoviral vectors for the treatment of disease, including their construction, propagation, and purification, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models. The book also considers the regulatory issues surrounding human clinical gene therapy trials. New chapters include adenoviral vaccines for veterinary applications, adenoviruses for gene editing, nonhuman primate adenoviruses, COVID-19 vaccines, vaccine applications, and oncolytic adenoviruses for antitumor immunization. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors.

  • Innovative Conservation Techniques and Perspectives

    Global Biome Conservation and Global Warming Impacts on Ecology and Biodiversity
    • 1st Edition
    • Germano Leão Demolin-Leite
    • English
    Innovative Conservation Techniques and Perspectives: Global Biome Conservation and Global Warming Impacts on Ecology and Biodiversity explores operational and potential monitoring tools to conserve and/or recover biomes at a global scale. Written by international experts in ecology and biodiversity conservation, this book identifies operational, emerging, and proposed methods for land monitoring and management across the world’s biomes. This important resource on biodiversity is an ideal resource for students, professors, researchers, and both governmental and non-governmental organizations active in biodiversity conservation.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 126
    • English
    Advances in Clinical Chemistry, Volume 126, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists. Chapters in this new release include Internalization of Extracellular Tau Oligomers in Alzheimer’s Disease, Advances in Neurofilament Light Chain Analysis, Biomarkers of Endometriosis, Lupus Nephritis II: Treatment and Monitoring, and Emerging Biomarkers in Type 2 Diabetes Mellitus, Coagulopathy Prediction in Traumatic Brain Injury.

  • Flow Cytometry in Immuno-oncology

    • 1st Edition
    • Volume 195
    • English
    Flow Cytometry in Immuno-oncology, Volume 173 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on timely topics, Basic principles of Flow cytometry in immuno-oncology, Good practice and methods for flow cytometry in immuno-oncology, Automated flow cytometry in immuno-oncology, Flow cytometric analysis of Tregs in solid tumors, Multiparametric analysis of Tumor infiltrating lymphocytes in solid tumors, Analysis of tumor-infiltrating immune cells in intracranial glioblastoma, Assessing chromosomal abnormalities in leukemias by Imaging flow cytometry, Flow cytometric analysis of cellular alkaline phosphatase in acute myeloid leukemia, and much more.

  • Biomedical and Clinical Cryogenics

    Theory, Current Technology Advances, and Future Perspectives
    • 1st Edition
    • Hussam Jouhara + 1 more
    • English
    Biomedical and Clinical Cryogenics: Theory, Current Technology Advances, and Future Perspectives presents the complexity of cryogenic engineering applications in both medical and clinical settings. The book demonstrates both a comprehensive and up-to-date understanding of ongoing, new applications and their cutting-edge breakthroughs within the biomedical engineering sector. It contributes to the rapidly emerging and expanding field of cryogenics by emphasizing the complexity of associated mechanisms and interactions. In six chapters, this book collects, investigates, and critically discusses state-of-the-art cryogenic practices, along with the challenges and perspectives of the most common applications.By using cryogenics sciences, new milestones in medicine and human-life expectancy can be significantly increased. Since this is highly interdisciplinary content, this book is a valuable resource for biomedical engineers, health professionals, scientists, researchers, students, and all those who wish to broaden their knowledge in the allied field.

  • Drug Delivery Landscape in Cancer Research

    • 1st Edition
    • Ranjita Shegokar + 1 more
    • English
    Drug Delivery Landscape in Cancer Research examines the combined impact of prevention, diagnosis, and treatment of cancer. With a strong focus on the status, challenges, and prospects of cancer drug delivery technology, the book examines clinical translation-related knowledge and the development of different organ related cancers. In 22 chapters, it describes current and new drug delivery systems in twenty different cancers and gives insights into drug delivery strategies and tumor microenvironment management in oral and ocular cancers. This book is a timely and valuable resource for health professionals, scientists, researchers, health practitioners, students, and anyone who wants to broaden their knowledge.

  • Revolutionizing Drug Discovery: Cutting-Edge Computational Techniques

    • 1st Edition
    • Volume 103
    • English
    Revolutionizing Drug Discovery: Cutting-Edge Computational Techniques is an essential guide for professionals, researchers, and students in the pharmaceutical and biotech industries, providing an in-depth look at how computational methods transform drug development. This book explores advanced tools like molecular modeling, machine learning, and AI-driven design, which accelerate drug discovery, enhance target identification, and improve clinical outcome predictions. Through real-world applications and case studies, readers gain practical insights into the benefits of computational approaches in managing data, optimizing leads, and predicting drug efficacy and safety. Emphasizing a multidisciplinary approach, it bridges chemistry, biology, and informatics, addressing both the technical and ethical dimensions of these innovations. This book is a roadmap to the future of medicine, revealing how computational advancements are reshaping the landscape of drug discovery.

  • Biodiversity, Bioengineering, and Biotechnology of Fungi

    • 1st Edition
    • Chakravarthula Manoharachary + 3 more
    • English
    Biodiversity, Bioengineering, and Biotechnology of Fungi examines various fungi genera and their biotechnological applications. The book covers the most common genera of fungi, their structure, their taxonomy, the maintenance and organization of a permanent study collection with associated databases, and their application in diverse sectors including industrial applications in the food, environment, bioenergy, biorefinery, and biopharma sectors.Compiled by an international team of fungal biologists, Biodiversity, Bioengineering, and Biotechnology of Fungi provides a wealth of information particularly on the diversity of fungal genera and their biotechnological contributions. The book is a valuable resource for scientists, researchers, health practitioners, nutritionists, industry professionals, advanced students, and all those who wish to broaden their knowledge in the allied field.

  • Nano-bioinoculants

    Smart Tools for Modern Agriculture
    • 1st Edition
    • Parul Chaudhary + 3 more
    • English
    Nano-bioinoculants: Smart Tools for Modern Agriculture discusses the interactions between nanoparticles and soil–plants–microbio... systems in a single-volume book designed to guide improvements in sustainable agriculture i.e. plant production and soil health. Past practices for the application of pesticides and chemical fertilizers have reduced the beneficial microbial diversity and soil fertility essential for optimal crop yield and overall plant health. As a result, developing innovative approaches to plant/soil health maintenance, bioremediation process, and stress management is advancing. Plant protection methods are increasingly being tailored to improve sustainable precision results, reduce environmental impact, and to target specific plant health challenges. Nano-bioinoculants: Smart Tools for Modern Agriculture explains nanoparticles and beneficial microbes and their impact on soil microbiomes, soil fertility restoration, remediation of contaminated soil, and plant health. It also highlights nanoparticles and bioinoculants in stress management, plant growth, and productivity, as well as covering the potentially toxic effect of nanoparticles on humans and the environment. This volume in the Nanomaterial-Plant Interactions series explores the potential of nano-biotechnology for better agronomic performance and sustainability.

  • Nanocarriers Based Colon Targeting

    Design, Development, Mechanism and Case Studies
    • 1st Edition
    • Lalit Kumar + 1 more
    • English
    Nanocarriers Based Colon Targeting: Design, Development, Mechanism and Case Studies unveils a groundbreaking exploration of nanotechnology’s potential in revolutionizing drug delivery for colon-related ailments. Today, an array of colonic diseases, including colorectal cancer, colonic polyps, ulcerative colitis, and inflammatory bowel syndrome, pose significant medical challenges. Conventional methods to deliver drugs to this system prove difficult, with limited efficacy and notable side effects. This book delves into the intricate complexities of colonic diseases, their pathophysiology, and epidemiology to support pharmaceutical scientists in designing better drug delivery systems. Providing a comprehensive overview of the area, the chapters elucidate diverse targeting strategies, from time-dependent to microbiota-based drug delivery systems, and explore receptor-based and magnetically assisted delivery mechanisms. Case studies dissected the working mechanisms behind polymeric nanoparticles, polymersomes, polymeric micelles, solid lipid nanoparticles, and other nanocarrier systems tailored for colon targeting. Additionally, this book explores cuttingedge topics such as gold nanoparticles, supra-magnetic iron oxide nanoparticles, and protein–peptide-base... nanoparticles, highlighting their mechanisms, applications, and potential toxicities. Merging an overview of colonic pathophysiology with in-depth reviews of each nanomaterial used for drug delivery and practical case studies, Nanocarriers Based Colon Targeting: Design, Development, Mechanism and Case Studies is a complete reference for pharmaceutical scientists involved in elevating drug delivery precision and therapeutic efficacy in this organ system. Toxicologists, material scientists, research physicians, and regulators can also benefit from the case studies developed by expert authors.

  • Integrated Pathy

    Re-envisioning Healthcare and Wellness Using India as a Case Study
    • 1st Edition
    • Acharya Balkrishna
    • English
    Integrated Pathy: Re-envisioning Healthcare and Wellness Using India as a Case Study brings together the best holistic treatments tailored to improve patient care. The book focuses on health and healing rather than disease and treatment. Instead of following the fragmented approach of modern and contemporary line, or more specifically, the allopathic regime of treatments, the book views patients as a complete entity inclusive of minds, spirits, and bodies, and includes these dimensions in diagnosis and treatment to provide a custom healing regime. Attention is paid to inherent lifestyle factors such as diet, exercise, quality of rest, sleep, and the nature of relationships.Reader... will find a fresh perspective on revitalizing traditional indigenous practices and the reliability and efficacy of so-called traditional and alternative therapies, both of which will undoubtedly contribute to the advancement of the ecosystem of research in this field.

  • Pharmacology, Physiology, and Practice in Obstetric Anesthesia

    • 1st Edition
    • Alan D. Kaye + 1 more
    • English
    Pharmacology, Physiology, and Practice in Obstetric Anesthesia provides all the essentials of obstetric anesthesia in a straightforward, user-friendly format that avoids encyclopedic language and lengthy discussions, and is inclusive of other healthcare specialties and subspecialties including obstetrics, neonatal care, and more. Coverage spans the essentials of obstetrics as well as overlooked issues including obstetric pharmacology and physiology safe practice strategies, clinical concepts for vaginal delivery and C-section, high-risk pregnancy states and management of the complicated parturient, complications and medicolegal, fetus and newborn considerations, and guidelines, standards and statements related to obstetric anesthesia.Pharmacol... Physiology, and Practice in Obstetric Anesthesia is the perfect reference for an interdisciplinary group of health professionals, policymakers, and researchers working and training in the field of obstetric anesthesiology

  • Nanotechnology of Veterinary Medicine and Livestock Production

    • 1st Edition
    • PK Gupta
    • English
    Nanotechnology of Veterinary Medicine and Livestock Production compiles the most impactful emerging research on the use of nanotechnology in animal sciences. This novel data, methods, and technologies will improve animal health, welfare, production, and nutrition, and will have implications for the future of human health, disease control, and food safety. Authored by a renowned animal toxicologist, this book introduces the history of nanotechnology in animal science before delving into its interdisciplinary applications. Central chapters explore nanomaterials in animal disease treatment, nanovaccine development, nanotechnology in animal nutrition and production, and applications for antibiotic-based therapies.Concluding chapters summarize the risks of these novel technologies, their challenges, and opportunities in various animal science sectors. This is an essential resource for researchers, clinicians, and animal scientists seeking information on cutting edge nano- and biotechnological advancements.

  • Essentials of Clinical Neurophysiology

    • 4th Edition
    • Karl E. Misulis + 1 more
    • English
    Up-to-date and easy to read, Essentials of Clinical Neurophysiology, Fourth Edition, details the basics of normal and abnormal neurologic function and provides authoritative clinical guidance on performing and interpreting today's full range of neurophysiologic studies. Drs. Karl E. Misulis and Thomas C. Head cover recent advances in technology as well as changes in training and practice patterns for EEG, EMG, EP, intraoperative monitoring, sleep studies, and autonomic testing. Offering a practical overview of this complex field, this one-stop resource is an excellent tool for board review and preparation.

  • Explainable AI in Healthcare Imaging for Medical Diagnoses

    Digital Revolution of Artificial Intelligence
    • 1st Edition
    • Tanzila Saba + 2 more
    • English
    In an era where Artificial Intelligence (AI) is revolutionizing healthcare, Explainable AI in Healthcare Imaging for Precision Medicine addresses the critical need for transparency, trust, and accountability in AI-driven medical technologies. As AI becomes an integral part of clinical decision-making, especially in imaging and precision medicine, the question of how AI reaches its conclusions grows increasingly significant. This book explores how Explainable AI (XAI) is transforming healthcare by making AI systems more interpretable, reliable, and transparent, empowering clinicians and enhancing patient outcomes.Through a comprehensive examination of the latest research, real-world case studies, and expert insights, this book delves into the application of XAI in medical imaging, disease diagnosis, treatment planning, and personalized care. It discusses the technical methodologies behind XAI, the challenges and opportunities of its integration into healthcare, and the ethical and regulatory considerations that will shape the future of AI-assisted medical decisions.Key areas of focus include the role of XAI in improving diagnostic accuracy in fields such as radiology, pathology, and genomics and its potential to enhance collaboration between AI systems, healthcare professionals, and patients. The book also highlights practical applications of XAI in personalized medicine, showing how explainable models help tailor treatments to individual patients, and discusses how XAI can contribute to reducing bias and improving fairness in medical decision-making.Writ... by leading experts in AI, healthcare, and precision medicine, Explain[S3G1] able AI in Healthcare Imaging for Precision Medicine is an essential resource for researchers, clinicians, students, and policymakers. Whether you are looking to stay at the forefront of AI innovations in healthcare or seeking to understand how explainability can build trust in AI systems, this book provides the insights and knowledge needed to navigate the evolving landscape of AI in medicine. It invites readers to explore how XAI can revolutionize healthcare and precision medicine, shaping a future where AI is both powerful and trustworthy.

  • Multifunctional Nanostructured Coatings

    Biomedical, Environmental, and Energy Applications
    • 1st Edition
    • Manviri Rani + 1 more
    • English
    Multifunctional Nanostructured Coatings: Biomedical, Environmental, and Energy Applications offers core and advanced information about various nanomaterials and their synthetic approaches to nanostructured coatings. The book focuses on the application of multifunctional nanostructured coatings (MNCs) in the areas of biomedicine, the environment, and energy, and presents the latest advances in the design, preparation, characterization, and fabrication of MNCs. Techniques covered in the book include chemical deposition (including plasma-assisted deposition) and physical deposition methods such as magnetron sputtering, arc evaporation, electron-beam evaporation, and ion-beam sputtering.In addition, the book also explores the use of multifunctional ZnO/TiO2 nanoarray composite coatings, Ta- and Si-doped multifunctional bioactive nanostructured films, in situ-generated titanium-oxo clusters, and silver nanoparticles. It will be useful for researchers working in the areas of materials science, coating technologies, nanotechnology, sustainability, and environmental engineering.

  • Preclinical Landscape in Cancer Research

    • 1st Edition
    • Ranjita Shegokar + 1 more
    • English
    Preclinical Cancer Landscape discusses the issues in preclinical-to-clini... translatability of molecularly targeted cancer therapies and the need to better align tumour biology in patients With a strong focus on the status, challenges, prospects and the need of robustness of preclinical cancer research, the book acknowledges that the bar for reproducibility in performing and presenting preclinical studies must be raised to facilitate a transparent discovery process that frequently and consistently leads to significant patient benefit. In 22 chapters this book describes the current status of preclinical research in multiple cancers. This book is a timely and valuable resource for health professionals, scientists and researchers, health practitioners, students, and all those who wish to broaden their knowledge in the allied field. " Preclinical landscape in cancer research " is written by experts in the field and informed with facts directly from manufacturers. Pharmaceutical scientists, medical researchers, biomedical engineers and clinical professionals will find this an essential reference.

  • CRISPR for Climate-Smart and Sustainable Agriculture

    • 1st Edition
    • Jen-Tsung Chen
    • English
    CRISPR for Climate-Smart and Sustainable Agriculture summarizes the current genome editing technology being used in food and energy crops. It presents methods and applications of CRISPR tools for breeding climate-smart and stress-tolerant crops that are better able to resist biotic and abiotic stressors due to climate change.Gene editing tools are increasingly seen as options for improving plant health and productivity. CRISPR is one such emerging and quickly advancing crucial technology for the research field of plant physiology, plant molecular biology, and crop breeding. CRISPR for Climate-Smart and Sustainable Agriculture focuses on genetic engineering using CRISPR technology for precision breeding of crops to achieve climate resilience, stress tolerance, and higher yield. Organized by specific plant challenges, this book presents expert insights from around the globe, providing updated knowledge of CRISPR with an emphasis on facing climate change and supporting sustainable agriculture.This volume in the Genome Modified Plants and Microbes in Food and Agriculture series will be valuable for researchers, academics, and advanced-level students seeking to understand and advance the use of CRISPR technologies toward the UN Sustainable Development Goals and the Paris Climate Agreement.

  • Metabolites as Signals in Immunity and Inflammation

    • 1st Edition
    • Zbigniew Zasłona + 2 more
    • English
    Metabolites as Signals in Immunity and Inflammation describes the revolution in the definition of the word metabolism, highlighting changes in thinking about the whole field of immunology. These changes occur thanks to breakthrough experiments in basic research, and with the help of new technologies that allow for the testing of immunology hypotheses. In recent years, a substantial number of findings have been made around immunometabolism. What is emerging is a complex interplay between metabolic reprogramming and immunity, which is providing an extra dimension to our understanding of the immune system in health and disease.

  • Advancing Healthcare through Decision Intelligence

    Machine Learning, Robotics, and Analytics in Biomedical Informatics
    • 1st Edition
    • Somen Dey + 4 more
    • English
    Advancing Healthcare through Decision Intelligence: Machine Learning, Robotics, and Analytics in Biomedical Informatics demonstrates real-world applications of decision intelligence - specifically machine learning, robotics, and analytics - to drive innovation and improvements in healthcare delivery and outcomes. The book provides a comprehensive overview of the latest developments in decision intelligence technologies, and offers a practical resource that can help navigate through the complex landscape of healthcare decision-making. In 5 themes Advancing Healthcare through Decision Intelligence: Machine Learning, Robotics, and Analytics in Biomedical Informatics focuses on the use of data analytics aad management techniques in healthcare to improve decision-making and healthcare outcomes, on the use of robotics, robots and genomics to improve biomedical informatics, on the use of genomics, clinical decision support systems (CDSS), machine learning, and deep learning to improve precision medicine and personalized treatment and on the ethical implications of using artificial intelligence (AI) in healthcare, ensuring trust in the technology, and making sure that it can be explained and understood by all stakeholders. This book is a valuable resource for health professionals, scientists and researchers, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.

  • Python for Quantum Chemistry

    A Full Stack Programming Guide
    • 1st Edition
    • Volume 23
    • Qiming Sun
    • English
    Quantum chemistry requires ever higher computational performance, with more and more sophisticated and dedicated Python scripts being required to solve challenging problems. Although resources for basic use of Python are widely (and often freely) available online and in literature, truly cohesive materials for advanced Python programming skills are lacking.Qiming Sun, a developer of the popular Python package PySCF, provides a comprehensive, end-to-end practical resource for researchers and engineers who have basic Python programming experiences chiefly in computational chemistry but want to take their use of the software forwards to the next level, the book provides an insightful exploration of Numpy, Pandas, and other data analysis tools. Readers will learn how to manage their Python computational projects in a professional way, with various tools and protocols for computational chemistry research and general scientific computing tasks exhibited and analysed from a technical perspective. Multiple programming paradigms including object-oriented, functional, meta-programming, dynamic, concurrent, and vector-oriented are illustrated in various technology scenarios allowing readers to properly use them to enhance their program projects. Readers will also learn how to use the presented optimization technologies to speed up their Python applications, even to the level as fast as a native C++ implementation. The applications of these technologies are then demonstrated using quantum chemistry Python applications.Python for Quantum Chemistry: A Full Stack Programming Guide is written primarily for graduate students, researchers and software engineers working primarily in the fields of theoretical chemistry, computational chemistry, condensed matter physics, material modelling, molecular simulations, and quantum computing.

  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 114
    • English
    Advances in Food and Nutrition Research, Volume 114, the latest release in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on the Nutraceutical potential of Mediterranean agri-food wastes and wild plants: green extraction and bioactive characterization, Yeast extract as a more sustainable food ingredient: Insights into flavor and bioactivity, Physical and chemical food safety hazards and associated health risks in seafood: a Mediterranean Perspective (Part I), Biochemical and microbial food safety hazards in seafood: A Mediterranean Perspective (Part II), Assessing food digestion in the elderly using in vitro gastrointestinal models, and much more.Additional chapters focus on Recent Advances in Non-Invasive Techniques for Assessing Food Quality: Applications and Innovations, Recent advances in carbohydrate phase behavior and rheology. Implications for processing and product formulation, and Recent advances in chemistry, biochemistry, and nutrition of dates palm fruit (Phoenix dactylifera L.) cultivars.

  • Intelligent Nanobiosystems in Medicine and Healthcare, Volume 1

    Fundamentals, Fabrication and Commercialization
    • 1st Edition
    • Vijay Mishra + 2 more
    • English
    Intelligent Nanobiosystems in Medicine and Healthcare, Volume One: Fundamentals, Fabrication and Commercialization provides an overview of recent progress in the nanobiosystems arena, helping readers design and develop novel drug delivery systems and devices that take advantage of recent advances in nanomedical technologies. The book explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advancement in cutting-edge nanomedical technologies. It highlights established research and technology on intelligent nanobiosystems, their rapidly emerging aspects, and future research directions. Sections cover nanobiosystems, explore nano candidates and fabrication aspects, and delve into the challenges of commercialization.Th... book will be a useful resource for researchers and postgraduate students in pharmaceutical sciences and biotechnology as well as medical professionals, biologists, chemists, materials scientists, clinical researchers, biochemical and biomedical engineers working both in academia and industry.

  • Intelligent Nanobiosystems in Medicine and Healthcare, Volume 2

    Applications of Intelligent Nanobiosystems
    • 1st Edition
    • Vijay Mishra + 2 more
    • English
    Intelligent Nanobiosystems in Medicine and Healthcare, Volume 2: Applications of Intelligent Nanobiosystems provides recent progress in the nanobiosystems arena, helping readers better design and develop novel drug delivery systems and devices that take advantage of recent advances in nanomedical technologies. The book explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advancements in cutting-edge nanomedical technologies. This updated volume includes chapters by experts in the field, featuring an exploration of targeted therapy and drug delivery systems, analytical and imaging tools, theranostics, tissue engineering and regenerative medicines, dentistry tools and modern developments.This book will be a useful resource for researchers and postgraduate students in pharmaceutical sciences and biotechnology industries as well as medical professionals, biologists, chemists, materials scientists, clinical researchers, and biochemical and biomedical engineers working both in industry and academia.

  • Neuroglia in Neurologic and Psychiatric Disorders, Part II

    • 1st Edition
    • Volume 210
    • English
    Neuroglia in Neurologic and Psychiatric Disorders, Part II discusses glia relative to neurologic and psychiatric disorders, emphasizing cross-disease-glial cell dysfunctions. Driven by advances in genetics, transcriptomics, electrophysiologic and imaging techniques, as well as by the increase in knowledge on neuropathologic features and underlying disease mechanisms, this book bridges the gap between neuroglia basic science and neuroglia clinical research.

  • Agriculture Toward Net Zero Emissions

    • 1st Edition
    • Sandeep Kumar + 1 more
    • English
    Agriculture Toward Net Zero Emissions explores how agriculture has historically contributed to carbon emissions and then takes the reader forward, offering insights into an integrated approach to reducing those emissions toward the COP26 goal. The dual challenge of increasing production to meet population and nutrition food demands while reducing the traditional emissions generated by production practices is significant. It requires understanding the foundation of current practices and then revising those underlying principles to reflect the resources and greater insights of today.This book provides an overview of the current state of the science, explores the development of policies and plans to improve carbon management, and provides examples of technology and agroecosystem management practices. It includes the latest updates in carbon neutral farming, carbon and energy management, and addresses the knowledge gap between input management, livestock management and agroecosystem management.Advancing agroecosystem science through a roadmap for improving capacity, Agriculture Toward Net Zero Emissions is a valuable resource for those seeking to develop and apply new agricultural best practices.

  • An Overview of FDA Regulated Products

    From Drugs and Cosmetics to Food and Tobacco
    • 2nd Edition
    • Eunjoo Pacifici + 1 more
    • English
    An Overview of FDA Regulated Products: From Drugs and Cosmetics to Food and Tobacco, Second Edition is fully updated to reflect recent advances in science and technology and new laws and regulations. Breakthroughs in cellular and gene therapy, immunotherapy, precision medicine, and digital health are changing the face of healthcare and regulation. The updates brought about by the 21st Century Cures Act and subsequent PDUFA Reauthorizations, as well as signing into law the “Modernization of Cosmetic Regulation Act of 2022,” which will transform FDA’s oversight of cosmetics, are fully reflected in all chapters of the book.This book provides graduate students and industry professionals with comprehensive information on approval processes with the FDA and other country regulation organizations. Regulatory science professionals working with not only drugs, but biologics, medical devices, food and additives, cosmetics, veterinary products, and tobacco will benefit from this comprehensive overview of the regulatory environment.

  • Encyclopedia of Bioinformatics and Computational Biology

    • 2nd Edition
    • Shoba Ranganathan + 2 more
    • English
    Bioinformatics and Computational Biology (BCB) combine elements of computer science, information technology, mathematics, statistics, and biotechnology, providing the methodology and in silico solutions to mine biological data and processes, for knowledge discovery.In the era of molecular diagnostics, targeted drug design, translational medicine and Big Data for personalized medicine, computational methods for data analysis are essential tools for biochemistry, biology, biotechnology, pharmacology, biomedical and computer science, as well as mathematics and statistics. New areas are emerging, and relatively isolated fields are becoming current hot research areas in BCB, such as Artificial Intelligence, Quantitative Biology, Computational Vaccinology, Epidemiology and Infection Diffusion, Synthetic Biology, and Phenomics. The role of BCB in characterizing SARS-CoV-2 variants and facing the COVID-19 pandemic is just one example of how these tools can help us better prepare for such future events.This Encyclopedia comprises three sections, covering Methods, Topics, and Applications. The methodologies and algorithms underpinning BCB are described in the Methods section; Topics covers traditional areas such as phylogeny, as well as more recent areas such as translational bioinformatics, cheminformatics and environmental informatics; Applications provides guidance for commonly asked “how to” questions.Navigating the maze of confusing jargon and the plethora of software tools is often confronting for students and researchers alike. This comprehensive and unique resource provides up-to-date theory and application content to address molecular data analysis requirements, with precise definitions of terminology and lucid explanations by field experts.

  • Viral Hepatitis in Asia and the Pacific

    Towards Elimination as a Public Health Threat
    • 1st Edition
    • Jing Sun + 2 more
    • English
    Viral Hepatitis in Asia and the Pacific: Towards Elimination as a Public Health Threat documents the narratives, innovations, and scope of work in the Asia-Pacific region in starting, consolidating, and moving towards the elimination of viral hepatitis. The Asia-Pacific region is disproportionately affected by viral hepatitis, accounting for two-thirds of the global burden. Countries from low-, middle- and high-income economies have adopted different strategies to address combating and eliminating viral hepatitis. The successful experiences of the Asia-Pacific region are valuable for other regions, especially the middle- and low-income countries moving towards the achievement of the 2030 goal of elimination.Strategi... discussed include integrated approaches, negotiating universal access to diagnostics, and treatment options, including vaccines. Content further covers the critical barriers to achieve the 2030 targets for elimination of viral hepatitis and how to overcome them. This is the perfect reference for all hepatology researchers and elimination policy advocates who are dedicated to joining the fight for the 2030 goal of the elimination of viral hepatitis as a public health threat.

  • Protein and Peptide Therapeutics

    • 1st Edition
    • Volume 212
    • English
    Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • CRISPR-Cas Systems for RNA and Genome Editing

    • 1st Edition
    • Volume 712
    • English
    CRISPR-Cas Systems for RNA and Genome Editing, Volume 711 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Massively parallel genomic perturbations with multi-target CRISPR interrogates Cas9 activity and DNA repair at endogenous sites, Genome oligopaint via local denaturation fluorescence in situ hybridization, Biochemical reconstitution of a type I-B CRISPR-associated transposon, Visualizing the conformational landscape of CRISPR-Cas9 through kinetics-informed structural studies, and much more.Additional sections cover Analysis of metal-dependent DNA nicking activities by Cas endonucleases, Biochemically characterizing the accessory proteins and ribonucleoprotein complexes of Type IV CRISPR systems, Prime editing in bacteria with BacPE, Preparation of high-purity CRISPR-based DNA base editor RNPs, Bacterial directed evolution of CRISPR base editors, Cloning and validating systems for high throughput molecular recording, Using CRISPR-Cas13 for viral nucleic acid detection, and more.

  • Clinical Landscape in Cancer Research

    • 1st Edition
    • Ranjita Shegokar + 1 more
    • English
    Cancer, a multifaceted disease, remains the leading cause of death worldwide. Ongoing research and technological advancements are continually improving the human understanding of newer treatment options. This book series aims to provide wide-ranging insights into the current landscape of cancer research, highlighting the recent advancements, current challenges, and future directions. Cancer varies widely in its formation, microenvironment, location in the body, associated risk factors, detection methodology, and treatment approaches. Early detection and prevention through lifestyle changes, regular screenings, and the awareness of symptoms are crucial for improving outcomes and survival rates. In this book series, the main focus is on trending topics, like new drug delivery, diagnostics, biomarkers, and preclinical and clinical developments in cancer research. Nanotechnology has emerged as a transformative approach in medicine, particularly in the areas of targeted drug delivery systems, imaging, and diagnostics to enhance the therapeutic efficacy and minimize adverse effects in cancer therapy. Advances in pharma, medical device, and diagnostic research, including the development of Trojan-horse therapies and precision treatments/assay kits, continue to enhance the effectiveness of cancer care over the past few decades. A total of five books are covered in this series: Drug Delivery Landscape in Cancer Research (Vol. 1)Biomarker Landscape in Cancer Research (Vol. 2)Diagnostic Landscape in Cancer Research (Vol. 3)Preclinical Landscape in Cancer Research (Vol. 4)Clinical Landscape in Cancer Research (Vol. 5) By integrating basic, applied, and innovative science concepts, this book series fosters a deeper understanding of the disease and paves the way for the development of more effective strategies. This book series serves as a valuable resource for students, researchers, regulators, and clinicians interested in understanding the complexities of cancer and the innovative approaches researched to combat this deadly disease. Nonetheless, continuous interdisciplinary, cross-country collaborations and cross-science innovation strategies are essential to further reduce the global cancer burden.

  • Neuroglia in the Healthy Nervous System, Part I

    • 1st Edition
    • Volume 209
    • English
    Neuroglia in the Healthy Nervous System, Part I provides insights into newly emerging developments in neuroglia biology, focusing on the healthy nervous system. Driven by advances in genetics, transcriptomics, electrophysiological... and imaging techniques, this volume bridges the gap between neuroglia basic science and neuroglia clinical research. The book provides an overview of neuroglia biology, highlighting emerging technologies used to unravel the role of neuroglial cells in specific brain functions. The book also discusses strategies using neuroglia as a therapeutic target.

  • Berry Fruits

    Bioactives, Health Effects and Processing
    • 1st Edition
    • Asli Can Karaca + 1 more
    • English
    Berry Fruits: Bioactives, Health Effects and Processing, Volume Eight in the Developments in Food Quality and Safety series, covers the most recent research on bioactives of berries, improvement of bioavailability and bioaccessibility of berry bioactives, processing of berries, and production of functional food ingredients obtained from berries. In eleven chapters, the book addresses, in detail, advanced technological applications in the sustainable production of berries, as well as bioactives/food ingredients obtained from berries. In addition, the book covers developments in novel processes for berries sustainable production, along with valorization of wastes and by-products of berry processing.The series is authored by a team of global experts in the fields of Food Quality and Safety, providing comprehensive knowledge to food industry personals and scientists.

  • Wheat Wild Relatives

    Developing Abiotic Stress Tolerance under Climate Change
    • 1st Edition
    • Mohd. Kamran Khan + 3 more
    • English
    Wheat Wild Relatives: Developing Abiotic Stress Tolerance under Climate Change presents a state-of-the-art outline of the problem, including issues, opportunities, and modern developments in the utilization of Wild Wheat Relatives (WWR) and related neglected species for wheat crop improvement, specifically focusing on environmental constraints. The book comprehensively discusses different wheat wild relatives, including major genus Triticum and Aegilops and their utilization in mitigating different environmental constraints using agronomic, physiological, and molecular approaches. Chapters provide insights into the advancement in the deployment of wheat genetic resources, including wild relatives and neglected species for crop improvement towards environmental issues.Wheat is a major staple food crop that has largely been focused for fulfilling the food requirements of world population during the Green revolution. Since then, it has come to cover more agricultural land than any other commercial crop. Continuously changing climatic conditions have drastically affected wheat production, with yields largely limited by environmental constraints. Theses production losses caused by crop vulnerability to climate change may be resolved by using wheat wild relatives that are closely related to cultivated genotypes and known for their beneficial traits.

  • Protein Misfolding in Neurodegenerative Diseases

    • 1st Edition
    • Neha Gogia + 2 more
    • English
    Protein Misfolding in Neurodegenerative Diseases is a comprehensive review of proteome homeostasis in neurons, and in the brain. Beginning with an introduction on factors involved in the formation and aggregation of misfolded proteins, chapters then discuss the precise cellular and molecular mechanisms involved in these processes and their role in neurodegeneration and disease. Additional topics of focus include protein clearance mechanisms like protein quality control, disease-modifiers, molecular druggable targets, novel therapeutics, and emerging techniques that block or delay disease onset or progression. This volume is relevant for researchers working with neurodegenerative diseases, including Alzheimer's disease, Parkinson’s disease, ALS, Creutzfeldt-Jakob disease, and more.

  • Federated Learning for Medical Imaging

    Principles, Algorithms, and Applications
    • 1st Edition
    • Xiaoxiao Li + 2 more
    • English
    Federated Learning for Medical Imaging: Principles, Algorithms, and Applications gives a deep understanding of the technology of federated learning (FL), the architecture of a federated system, and the algorithms for FL. It shows how FL allows multiple medical institutes to collaboratively train and use a precise machine learning (ML) model without sharing private medical data via practical implantation guidance. The book includes real-world case studies and applications of FL, demonstrating how this technology can be used to solve complex problems in medical imaging. The book also provides an understanding of the challenges and limitations of FL for medical imaging, including issues related to data and device heterogeneity, privacy concerns, synchronization and communication, etc.This book is a complete resource for computer scientists and engineers, as well as clinicians and medical care policy makers, wanting to learn about the application of federated learning to medical imaging.

  • Handbook of Food Allergen Detection and Control

    • 2nd Edition
    • Simon Flanagan
    • English
    Handbook of Food Allergen Detection and Control, Second Edition continues to be an essential resource of scientific and technical information in the food and analytical communities. This book provides information on current and emerging technologies for detecting and reducing allergens to improve allergen control overall. Written by experts in the field, it offers a wide scientific perspective on allergens and includes hot topics such as food allergen labeling and consumer perspectives on food allergen labels. Chapters are fully revised to include the latest information in the industry, including practical applications of new methods and control strategies. The book is useful for anyone in the food supply chain.The book reviews current and emerging technologies for detecting and reducing allergens, as well as issues such as traceability, regulation, and consumer attitudes. Following an introductory chapter by a distinguished expert, Part One covers allergen management throughout the food chain. Part Two details current and emerging methods of allergen detection in food, with Part Three covering methods for reducing and eliminating allergens in food. Finally, Part Four focuses on the control and detection of individual food allergens and the risks each one presents in food manufacturing.

  • Energy Drinks

    Composition, Consumption, and Cautions
    • 1st Edition
    • John Higgins + 1 more
    • English
    After reports of adverse events associated with energy drink consumption, including trouble sleeping, anxiety, cardiovascular events, seizures, and even death, concerns have been raised about their safety and efficacy. Energy Drinks: Composition, Consumption, and Cautions will focus on these popular beverages, their composition, ingredients, consumption patterns, performance-enhancin... effects, and their potential negative side effects and health risks. This book will go on to make recommendations that call for education, regulatory actions, changes in marketing, and additional research.The research about energy drink safety and efficacy is often contradictory, and much of the available literature is industry sponsored. This book will offer a single, unbiased, up-to-date resource for researchers, healthcare providers, and industry regulators to understand the full scope of energy drinks and their associated health risks.

  • Multi-Omics Technology in Human Health and Diseases

    Genomics, Epigenomics, Transcriptomics, Proteomics, Metabolomics, Radiomics, Multi-omics
    • 1st Edition
    • Muzafar A Macha + 2 more
    • English
    Multi-Omics Technology in Human Health and Diseases: Genomics, Epigenomics, Transcriptomics, Proteomics, Metabolomics, Radiomics, Multi-omic offers an advanced exploration into the comprehensive understanding of disease etiology and prognosis through multiomics approaches. This authoritative volume delves into the applications of multiomics technology in elucidating complex human health conditions and diseases. It introduces the technology's potential for biomarker identification, drug discovery, and disease prognostication. For a thorough understanding of human health and diseases, particularly cancer, it is essential to integrate knowledge of molecular biomarkers across multiple omics levels, including the genome, epigenome, transcriptome, proteome, and metabolome. This resource addresses the current gaps in knowledge among students and researchers, providing in-depth coverage of multiomics technology and its implementation in scientific research and discovery.Multi-Omic... Technology in Human Health and Diseases: Genomics, Epigenomics, Transcriptomics, Proteomics, Metabolomics, Radiomics, Multi-omics is a pioneering resource that presents cutting-edge information on contemporary multiomics technologies for big data interpretation and their applications in deciphering complex human pathobiology. This comprehensive guide is indispensable for researchers, academics, students, and industry professionals alike.

  • Human- Centric Integration of Next-Generation Data Science and Blockchain Technology

    Advancing Society 5.0 Paradigms
    • 1st Edition
    • Amit Kumar Tyagi + 1 more
    • English
    Human- Centric Integration of Next Generation Data Science and Blockchain Technology: Advancing Society 5.0 Paradigms focuses on the current technological landscape, addressing the evolving integration of data science and blockchain within the context of Society 5.0. This comprehensive resource explains the convergences between data science, blockchain, and the human-centric vision of Society 5.0, while also filling the gap in understanding and navigating this transformative intersection with recent shifts towards more decentralized and data-driven paradigms.The book introduces the concept of Society 5.0, examining the historical context, and outlines the evolving technological landscape shaping our interconnected future. It discusses the fundamental principles of data science, from data collection and preprocessing to exploratory data analysis and explains the transformative impact of data science and blockchain across industries such as healthcare, finance, education, and transportation. This book is essential to understanding and shaping the future of technology and society from decentralized solutions to predictive analytics/ emerging technologies.

  • Lipid-Drug Conjugates

    Innovation and Applications
    • 1st Edition
    • Malay K. Das
    • English
    Lipid-Drug Conjugates: Innovation and Applications highlights the most recent advances and clinical applications of nano lipid-drug conjugates for enhanced drug delivery and targeting in the treatment of cancer, glioblastoma, Alzheimer’s, AIDS, and bacterial diseases. In addition, various conjugation methods to prepare lipid-drug conjugates and their pharmacokinetics in vivo are explored, together with the production and characterization of various delivery carriers for lipid-drug conjugates. The contents of this book provide pharmaceutical science researchers with the tools to explore targeted drug delivery leveraging the unique characteristics of lipid conjugates. Scientists in the corporate setting can benefit of the cases and techniques presented in developing new formulations and products.

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