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Elsevier

Books in Life sciences

  • Neuroscience of Coffee Part A

    • 1st Edition
    • Volume 288
    • English
    The Neuroscience of Coffee is a pioneering volume that delves into the intricate relationship between one of the world's most beloved beverages and the human brain. Offering a comprehensive exploration of the biochemical and physiological mechanisms underlying coffee's impact on the nervous system, this groundbreaking book transcends traditional coffee literature by focusing specifically on the neurological aspects. From deciphering the molecular intricacies of caffeine to examining the complex interactions within the nervous system, the volume provides an unprecedented insight into how coffee influences brain function, mental health, and neurodegenerative diseases. It addresses the growing interest in understanding everyday dietary choices and their neurological implications, filling a crucial gap in accessible yet detailed resources. This book not only contributes to the evolving field of neuroscience but also serves as a valuable guide for professionals, students, and informed laypersons seeking a deeper understanding of coffee's effects on brain health and overall well-being.

  • Comprehensive Hematology and Stem Cell Research

    • 1st Edition
    • Nima Rezaei
    • English
    **2025 PROSE Award Category Winner in Clinical Medicine**Comprehens... Hematology and Stem Cell Research is the first major reference to cover both stem cell research and therapy as well as the range of hematological disorders they are currently used to treat and may potentially be able to treat in the future. This five volume set includes fundamentals, such as the underlying mechanisms of the blood and immune system, highlighting blood disorders and cancers of the blood, including lymphoma, leukemia, and myeloma. Other sections cover stem cell research and therapy, from harvesting stem cells to their utilization in cancer treatments.Finally, the work looks to the future and explores newer stem cell research that may lead to future treatments. This book is an excellent resource for students at the graduate and post-graduate levels, academics, and researchers in the fields hematology, immunology and oncology.

  • Natural Antioxidants to Enhance the Shelf-Life of Food

    • 1st Edition
    • Mirian Pateiro
    • English
    Natural Antioxidants to Enhance the Shelf-Life of Food, Volume Two in the Developments in Food Quality and Safety series is the most up-to-date resource covering trending topics such as the analysis of toxic compounds and control of food poisoning, food fraud, traceability and authenticity, revalorization of agrifood industry, and natural antimicrobial compounds and their applications to improve the preservation of food, non-thermal processing technologies, nanotechnology in food production, and intelligent packaging and sensors for food applications. The book focuses on recent advances and strategies to use these compounds in the preservation of food.Chapters explore advances in antioxidant activity analysis, electrochemical methods, food oxidative stability, and natural antioxidants from agro-industrial by-products. Natural antioxidants from marine sources and innovations in antioxidants films and coatings are also covered. The series is edited by Dr. José Manuel Lorenzo and authored by a team of global experts in the fields of Food Quality and Safety, providing comprehensive knowledge to food industry personals and scientists.

  • Active Peptides for Skin Care

    • 1st Edition
    • Wenfeng Ding
    • English
    Active Peptides for Skin Care is one of the first books on the market that specifically deals with the application of peptides in the field of skin care. The book outlines the basic background to skin and peptides, describes the technical methods for transdermal administration of peptides to exert their effects, and introduces the key issue of quality control methods commonly used to ensure the effectiveness and safety of peptides.The book also covers the mechanism of action and application cases of different efficacies of skin peptides, such as: whitening and spot removal, prolonging and repairing, anti-allergy and soothing, anti-hair loss and growth, improving wrinkles, breast enlargement and slimming, acne repair, eye care, repairing stretch marks, etc.

  • Concepts and Techniques in OMICS and System Biology

    • 1st Edition
    • Asmat Farooq + 5 more
    • English
    Concepts and Techniques in OMICS and Systems Biology provides a concise and lucid account on the technical aspects of omics, system biology and their application in fields of different life science.With a strong focus on the fundamental principles understanding of metabolomics, ionomics and system biology, the book also gives an updated account on technical aspects of omics and system biology. Since both omics and systems biology fields are fast advancing filed of biological sciences, its significance and applications need to be understood from the baseline.In 10 chapters Concepts and Techniques in OMICS and Systems Biology introduces the reader to both Proteomics, Metabolomics and Ionomics, and System Biology, the technical applications, describes both the software in for proteomics as metabolomic enumeration and preludes Omics technologies and their applications.The chapters are designed in a well-defined chronology such that readers will understand the concepts and techniques involved in omics and system biology. This compilation will be ideal reading material for students, researchers and people working in the industries related to biological sciences.

  • Ecophysiology and Ocean Acidification in Marine Mollusks

    From Molecule to Behavior
    • 1st Edition
    • Youji Wang
    • English
    Ecophysiology and Ocean Acidification in Marine Mollusks: From Molecule to Behavior provides an extensive overview of the latest research on the various ecophysiological effects of ocean acidification on marine mollusks. This book synthesizes historical information and recent findings on the effects of environmental change, ocean warming, and acidification on key mollusks and their life-history. It also discusses the underlying mechanisms underpinning the effects of ocean warming and acidification. Written by internationally recognized experts in the field of marine biology, this book systematically examines the effects of ocean acidification on the reproduction, growth and development, physiological metabolism, immunity, and behavior of marine mollusks.The book concludes by discussing the implications of current research, acknowledging data limitations in the field, and proposing future research directions, providing a better understanding of the potential impacts of ocean acidification on mollusks and the global aquaculture industry and inspiring new thinking for future research practices. It will be an indispensable resource for researchers, practitioners, undergraduate and graduate students, conservationists, and aquaculturists alike who are interested in marine environmental change, ecology, physiology, and marine biology.

  • Cannabis and Khat in Drug Discovery

    The Discovery Pipeline and the Endocannabinoid System
    • 1st Edition
    • Andrew G. Mtewa + 4 more
    • English
    Cannabis and Khat in Drug Discovery: The Discovery Pipeline and the Endocannabinoid System provides comprehensive coverage of two important psychoactive plants: Khat and Cannabis. Initial research has found that compounds and derivatives from Cannabis and Khat are found to have promising properties that can be used for the discovery, design and development of potential drug leads against various diseases. This book extensively discusses the drug discovery and allied sciences of these compounds in the drug discovery pipeline, including basic research and computer aided modeling in ligand-drug interactions and their interactions with the endocannabinoid system. Categorized into sections including, chemical analyses and bioassays, medicinal chemistry, chemical biology and pharmacology, clinical applications, and policy and regulations, this book covers the methods and protocols involved and will be of interest to students, researchers, policymakers and all those involved in drug discovery research.

  • Physico-Chemical Aspects of Dosage Forms and Biopharmaceutics

    Recent and Future Trends in Pharmaceutics, Volume 2
    • 1st Edition
    • Amit Kumar Nayak + 1 more
    • English
    Physico-Chemical Aspects of Dosage Forms and Biopharmaceutics: Recent and Future Trends in Pharmaceutics, Volume Two explores aspects of pharmaceutics with an original approach that focuses on technology, novelties and future trends. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day, so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. Readers will find practical information for conducting research in pharmaceutics that is ideal for researchers in academia and industry as well as advanced graduate students in pharmaceutics.In addition, the book discusses the most recent developments in biopharmaceutics, including important and exciting areas such as solubility of drugs, pharmaceutical granulation, routes of drug administration, drug absorption, bioavailability and bioequivalence.

  • Environmental Health Behavior

    Concepts, Determinants, and Impacts
    • 1st Edition
    • Ana Virgolino + 2 more
    • English
    The unique biological capacities of humankind enabled the emergence of organized societies and sophisticated and globalized cultures. The progressive and universal recognition of science and technology as bulwarks of our species' survival, longevity, and quality of life made individual and organizational behaviors the main drivers of current (and future) human and planetary health standards.Environmen... Health Behavior: Concepts, Determinants, and Impacts, integrates two different but intertwined fields, environmental health sciences and human behavior sciences, identifying and systematizing current knowledge about human behaviors and habits, and addressing the challenge of environmental sustainability. The book takes the reader through a conceptual framework for environmental health behavior (EHB) as an emerging field of public and environmental health, positioning behavior change as the main challenge for the success of promoting sustainable human and planetary health. Its reading promotes insight into the environmental impacts of human demands and behavior, and, vice-versa, about the impacts of the environment on human behavior change. Moreover, different evidence-based strategies to promote EHB change are identified as practical tools for stakeholders involved in the challenge of promoting intergenerational well-being in balanced and sustainable human-produced and natural systems.

  • Hormones and Reproduction of Vertebrates, Volume 5

    Mammals
    • 2nd Edition
    • David O. Norris + 1 more
    • English
    Hormones and Reproduction of Vertebrates, Volume 5: Mammals is the fifth of five second-edition volumes representing a comprehensive and integrated overview of hormones and reproduction in fishes, amphibians, reptiles, birds, and mammals. The book includes coverage of endocrinology, neuroendocrinology, physiology, behavior, and anatomy of mammalian reproduction. It provides a broad treatment of the roles of pituitary, thyroid, adrenal, and gonadal hormones in all aspects of reproduction, as well as descriptions of major life history events. New to this edition are chapters on the evolution of viviparity, reproduction of ungulates, carnivores, and marine mammals as well as a concluding assessment of the effect of environmental influences on mammals.The initial chapters in this book broadly examine sex determination, reproductive neuroendocrinology, stress, and hormonal regulation as they relate to male and female reproductive structure and function. Subsequent chapters introduce the evolution of viviparity and examine pregnancy in eutherian mammals, parturition, pheromones, and behavioral neuroendocrinology. The book concludes with an examination of the environmental influences on hormones and reproduction of mammals, including endocrine-disrupting chemicals and climate change.

  • Fundamentals of Health Neuroscience

    • 1st Edition
    • Yi-Yuan Tang + 1 more
    • English
    Health Neuroscience is a new interdisciplinary field encompassing research from cognitive, affective, and social neuroscience, health psychology, physical and mental health, and science of behavior change. This new field addresses the longstanding gap among neuroscience, health, and behavior change within the context of health promotion.Fundamenta... of Health Neuroscience explores key topics and research, including basic principles, psychological and neural processes, brain and body interactions, and gene x brain x environment interactions. This book also covers brain-based precision prevention and intervention strategies for health decisions and promotion across the lifespan. Chapters integrate the latest research findings and explores several key topics, such as: How does the brain serve both as a predictor and an outcome of health? How can people improve self-control and achieve physical and mental health effectively? What does brain plasticity and resilience tell us about optimal learning, performance, and development throughout our life? How is the sense of meaning in life affected by dopamine and reward systems in the brain?

  • Microbes, Microbial Metabolism and Mucosal Immunity

    An Overview
    • 1st Edition
    • Tanima Bose
    • English
    Microbes, Microbial Metabolism and Mucosal Immunity: An Overview presents a concise and well-vetted treatise on the study of microbiome and microbial metabolites. This volume is up-to-date with the most recent developments from the last decade. It encompasses the interaction of immunity and microbes — and their metabolites — from different mucosal organs including gastrointestinal system, lung, oral cavity, eye. Along with the efficiency of the immune system in inhibiting the growth and proliferation of microbes, the volume discusses how the mediators of the immune system can be targeted to develop therapies.This book presents the latest methods, gives broad and systematic coverage of most mucosal systems and diseases, and takes a fresh perspective that looks at the functional aspects of change in the microbiome. The study of microbiome and microbial metabolites and their roles in host mucosal immunology is a rapidly developing area of research. One major way in which the microbiome influences the host is through altered metabolism. Metabolites, readily available to the host, engender significant consequences. Microbial metabolites have been shown to impact the disease processes in both proximal and distal organs, including the brain in several neurocognitive disorders.

  • Endophytic Fungi

    The Full Story of the Untapped Treasure
    • 1st Edition
    • Ahmed M. Abdel Azeem + 2 more
    • English
    Endophytic Fungi: The Full Story of the Untapped Treasure covers the developments in endophytic fungal research from beginning to the end by the eminent researchers involved in the field. It sheds light on the endophytic fungal current research, challenges, and future possibilities, the trending recent topics in the plant-fungal endophytes' biodynamics for sustainable development of bioproducts and its applications are supported in large-scale biosynthesis of industrially and pharmaceutical important biomolecules.Endophy... Fungi: The Full Story of the Untapped Treasure highlights the bioprospecting and applied aspects of endophytic fungal communities from diverse hosts and discusses the practical applications of such endophytes in detail. It also reviews recent strategies on alternative sustainable sources of medicines such as secondary metabolites of fungi instead of over collection of plants under prohibiting of biodiversity conventions. The uniqueness of this book is the inclusion of updated bioinformatics-based strategies and its importance in bioactive molecules produced by endophytic fungi. The book addresses one of the most eminent issues in this field: how to translate the potential that endophytic fungi hold in stable practical application.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 122
    • English
    Advances in Clinical Chemistry, Volume 122, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists.

  • Fatty Acid-Binding Proteins and Their Roles in Human Health and Disease

    From Basic Science to Clinical Application
    • 1st Edition
    • Asim K. Duttaroy
    • English
    Fatty Acid-Binding Proteins and Their Roles in Human Health and Disease: From Basic Science to Clinical Application presents the latest information on the contributions of different FABPs in physiology and pathophysiology, along with their importance in clinical outcomes. The book is divided into six main sections that cover FABP biology and their role in inflammation and diseases, such as cardiovascular, neurological, and liver diseases, to FABPs and their clinical applications.Each chapter thoroughly reviews current literature, primary research data and clinical cases, providing readers with an overview of the latest information in the expanded field of FABPs. This is an invaluable resource for both researchers and clinicians familiar with and those new to the exciting and everchanging world of fatty acid-binding proteins and clinical disorders.

  • Food Waste Valorization

    Emerging Trends, Techno-economic and Environmental Considerations
    • 1st Edition
    • Olalere Olusegun Abayomi + 2 more
    • English
    Food Waste Valorization: Emerging Trends, Techno-economic and Environmental Considerations covers bioactive extraction, therapeutic properties and environmental concerns related to food waste conversion to value-added products, along with advanced technological breakthroughs in the field. The book also provides concepts and theories on several facets of agro-food waste valorization and its by-products, as well as opportunities and challenges. Each chapter contains viewpoints from different fields of research such as Basic Science, Agriculture, Food Science and Engineering, Chemical Engineering, Mechanical Engineering, Environmental Science, and more, with each having a unique approach to food waste valorization as it relates to their field. This is an invaluable resource for research and development professionals in post-harvest processing and renewable energy industries, as well as the academicians.

  • Hematopoietic Stem Cell Transplantation for Neurologic Diseases

    • 1st Edition
    • Volume 202
    • English
    Hematopoietic Stem Cell Transplantation for Neurological Diseases (HSCT), Volume 201 provides the latest information on what has been evaluated as a possible therapeutic tool in severe autoimmune diseases for the last 20 years. In the neurological field, HSCT has been widely investigated for the treatment of multiple sclerosis and evidence is accumulating about its potential use in neuromyelitis optica, stiff person syndrome, myasthenia gravis, and many immune neuropathies. Besides their strong clinical relevance, studies on HSCT in neurological diseases have contributed to new insights on the pathological mechanisms underlying CNS autoimmunity, hence this volume summarizes that research.

  • Hormones and Reproduction of Vertebrates, Volume 4

    Birds
    • 2nd Edition
    • David O. Norris + 1 more
    • English
    Hormones and Reproduction of Vertebrates, Volume 4: Birds is the fourth of five second-edition volumes representing a comprehensive and integrated overview of hormones and reproduction in fishes, amphibians, reptiles, birds, and mammals. The book covers endocrinology, neuroendocrinology, physiology, behavior, and anatomy of avian reproduction. It provides a broad treatment of the roles of pituitary, thyroid, adrenal, and gonadal hormones in all aspects of reproduction, as well as descriptions of major life history events. New to this edition is a concluding assessment of the effect of environmental influences on birds.The initial chapters in this book broadly examine sex determination, reproductive neuroendocrinology, stress, and hormonal regulation as they relate to male and female reproductive structure and function. Subsequent chapters examine hormones and reproduction of specific behaviors, including courtship, mating, parental care, and migration.

  • Neuropsychological and Psychosocial Foundations of Neuro-Oncology

    • 1st Edition
    • Herbert B. Newton + 1 more
    • English
    Neuropsychological and Psychosocial Foundations of Neuro-Oncology provides an in-depth review of common cognitive, psychological, and social manifestations that occur in patients with brain cancer and other neuro-oncological issues. Chapters discuss primary CNS tumors, brain metastases, leptomeningeal disease, paraneoplastic disorders, and many other topics. Effects of CNS and systemic cancer treatment (i.e., radiotherapy, chemotherapy, immunotherapy) are also examined, as are current practices for rehabilitation and targets for essential future interventions in vulnerable populations.This book is fully illustrated with pathology photomicrographs, CT and MRI images, tables, and molecular pathway diagrams. Bringing neuropsychological and behavioral health trial knowledge from the bench to the bedside, this volume is an essential reference for practicing neuro-oncologists, neuropsychologists, nurses, and others working in the field of neuro-oncology.

  • Hormones and Reproduction of Vertebrates, Volume 3

    Reptiles
    • 2nd Edition
    • David O. Norris + 1 more
    • English
    Hormones and Reproduction of Vertebrates, Volume 3: Reptiles is the third of five second-edition volumes representing a comprehensive and integrated overview of hormones and reproduction in fishes, amphibians, reptiles, birds, and mammals. The book covers endocrinology, neuroendocrinology, physiology, behavior, and anatomy of reptilian reproduction. It provides a broad treatment of the roles of pituitary, thyroid, adrenal, and gonadal hormones in all aspects of reproduction, as well as descriptions of major life history events. The initial chapters in this book broadly examine sex determination, reproductive neuroendocrinology, stress, and hormonal regulation as they relate to testicular and ovarian function. Subsequent chapters examine hormones and reproduction of specific taxa, including turtles, crocodilians, lizards, and snakes. The book concludes with an examination of environmental influences on reproduction of reptiles.

  • Smart Food Safety

    • 1st Edition
    • Volume 111
    • English
    Smart food safety series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Mitochondrial Transplantation and Transfer

    Biology, Methods, Applications, and Disease
    • 1st Edition
    • Gokhan Burcin Kubat + 2 more
    • English
    Mitochondrial Transplantation and Transfer: Biology, Methods, Applications, and Disease, a volume in the Translational and Applied Bioenergetics series, offers a detailed overview of mitochondrial transplantation across fundamental biology, disease and early therapeutics research. Here, more than twenty experts in the field discuss transplantation and transfer of healthy mitochondria and define future steps to improve new therapeutic applications across a variety of diseases. Emphasis is placed on the physiology of mitochondrial transfer, isolation processes and their applications, transfer methods, and diagnostic and treatment use across cardiovascular, metabolic, and neurological diseases, among other disease types. Step-by-step instruction is provided around research protocols and methods discussed, along with careful attention to the ethical implications of mitochondrial transplantation research and application.

  • Update on Endocrine Disorders During Pregnancy, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 53-3
    • Maria Papaleontiou + 1 more
    • English
    In this issue of Endocrinology and Metabolism Clinics of North America, guest editors Drs. Rachel Pessah-Pollack and Maria Papaleontiou bring their considerable expertise to the topic of Update on Endocrine Disorders During Pregnancy. In recent years, our understanding of endocrine disorders during pregnancy has greatly evolved and changed. In this issue, top experts provide updates on transgender reproductive health, PCOS management during pregnancy, hypertension, diabetes, congenital adrenal hyperplasia during pregnancy, and more.

  • Advances in Parasitology

    • 1st Edition
    • Volume 125
    • English
    Advances in Parasitology, Volume 125 provides detailed and comprehensive reviews written by experts covering all aspects of parasitology. Chapters in this new release include New directions for malaria vector control using geography and geospatial analysis, PfEMP1 – Still of key importance in Plasmodium falciparum malaria immunity and pathogenesis, and Fish Ectoparasite Detection, Collection and Curation.

  • Quick Guide to Endocrinology

    The Pediatric Version
    • 2nd Edition
    • William E. Winter + 2 more
    • English
    Quick Guide to Endocrinology, The Pediatric Version, Second Edition, continues to be an essential resource which focuses on the physiology, diagnostics, and laboratory testing of endocrine (hormone-mediated) disorders encountered in the field of endocrinology with expanded coverage of pediatric endocrinology. The guide is for laboratory scientists and technicians, as well as trainees and clinicians in the field of pediatrics and pediatric endocrinology including fellows, residents, medical students, nursing students, and advance practice providers and students. It is presented in an easy to read, quick format, the physiology and method of measurement for hormones essential to many bodily processes and how their dysregulation results in disease. The characteristics of such diseases and diagnostic testing including up-to-date molecular testing is addressed.

  • Melatonin

    A Ubiquitous Pleiotropic Molecule
    • 1st Edition
    • Sheikh Mansoor + 3 more
    • English
    Melatonin: A Ubiquitous Pleiotropic Molecule equips researchers with an understanding of the molecular biology of melatonin in plants. The book explores the occurrence of melatonin in several plant species, covering key aspects, including its biosynthesis, physiological function in plant growth and development, and signaling pathways. It then discusses the benefits melatonin has for plant and agricultural development, as well as how it can be utilized as a therapeutic in the treatment of human diseases. The role it can play in the oxidative stress response and circadian rhythm modulation are covered, as well as its nutraceutical potential for human health.The book also covers the importance of melatonin in a range of fields, including drug discovery and disease resistance, agriculture, botany, and biotechnology, and is an ideal reference for researchers across these disciplines.

  • Redox Signaling

    • 1st Edition
    • Volume 162
    • English
    Advances in Cancer Research, Volume 162 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Artificial Intelligence in Microbiology: Scope and Challenges Volume 1

    • 1st Edition
    • Volume 55
    • English
    Nowadays, the field of microbiology is undergoing a revolutionary change due to the emergence of Artificial Intelligence (AI). AI is being used to analyze massive data in a predictable form, about the behavior of microorganisms, to solve microbial classification-relat... problems, exploring the interaction between microorganisms and the surrounding environment. It also helps to extract novel microbial metabolites which have been used in various fields like medical, food and agricultural industries. As the pace of innovation in Microbiology is accelerating, the use of AI in these industries will be beneficial. AI will not only show its extraordinary potential in expanding the market of antibiotics, food, and agriculture but also offer an eco-friendly, safer, and profitable solution to the respective industries. It would be challenging to search out specific features and discuss future research on AI in microbiology with a wide perspective.

  • Microbial Genomics: Clinical, Pharmaceutical, and Industrial Applications

    • 1st Edition
    • Huseyin Tombuloglu + 1 more
    • English
    Microbial Genomics: Clinical, Pharmaceutical and Industrial Applications focuses on the various applications of microbial genomics in clinical, pharmaceutical, and industrial fields. The book consists of four parts devoted to bacterial, viral, and fungal genomics, as well as their applications in clinical, pharmaceutical, and industrial fields. Chapters are written by experts in their respective disciplines and are tightly organized with an introduction to detailed descriptions, available software implementation, applications, advanced topics, summaries, analytic questions, exercises, and suggested readings. Throughout this book, the latest genomics and biotechnological developments and discoveries as well as open problems and future challenges on microbial genomics are highlighted. Readers will be introduced to state-of-the-art developments and trends of microbial genomics, its clinical, pharmaceutical, and industrial applications.

  • The Rose and Mackay Textbook of Autoimmune Diseases

    • 7th Edition
    • M. Eric Gershwin + 2 more
    • English
    **Selected for 2026 Doody's Core Titles in Allergy/Clinical Immunology**The Rose-Mackay Textbook of Autoimmune Diseases, Seventh Edition is a comprehensive reference that emphasizes the "3 P’s" of 21st Century medicine: precision, prediction, and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients.This new edition continues its success with 75% of the content revised, updated, or completely new. This edition is a valuable resource to clinicians involved in the diagnosis and treatment of autoimmune disease, as well as to scientists who want to follow developments in the field.

  • Diagnostic, Prognostic, and Therapeutic Role of MicroRNAs in Head and Neck Cancer

    • 1st Edition
    • Ashok Kumar + 3 more
    • English
    Diagnostic, Prognostic and Therapeutic Role of MicroRNAs in Head and Neck Cancer provides detailed information on various miRNA-based approaches for the diagnosis, prognosis, and treatment of HNSCC. The book encompasses various miRNA-based point-of-care diagnostics and drug delivery systems for HNSCC, along with information on clinical trials for improved clinical outcomes in HNSCC patients. In addition, it provides a comprehensive overview of currently available miRNAs associated with HNSCC and their extensive application for early diagnosis, prognosis, and treatment. Scientists and clinicians looking to win the battle against HNSCC will benefit from the book's sections on early diagnosis to improve treatment, increase treatment response rates, and reduce mortality rates. Recently, miRNA-based diagnostics and therapeutics have gained considerable attention among the scientific community. MiRNAs are known to have great potential as biomarkers for early diagnosis, prediction, and prognosis of HNSCC, and play a role in development of targeted gene therapy.

  • The Science and Art of Sensory Processing Sensitivity

    • 1st Edition
    • Bianca P. Acevedo
    • English
    The Science and Art of Sensory Processing Sensitivity provides an up-to-date and novel scientific perspective on the biologically based Sensory Processing Sensitivity (SPS) trait— which is associated with enhanced awareness, depth of cognitive processing, and heightened responsivity to the environment and other individuals. This second volume by B.P. Acevedo, following “The Highly Sensitive Brain,” takes a scientific perspective on its exploration of SPS, but adds to the existing body of literature on high sensitivity by including an enhanced discussion on the proposed mechanisms linking it with depression, anxiety, and burnout.In addition, this second volume explores SPS’ relationship to other relevant personality traits, such as the Big Five, creativity, and sensation seeking; and sheds light on how their varying combinations give rise to different outcomes for highly sensitive persons (HSPs). A unique contribution of this volume is its detailed examination of the role of culture, gender, biology, aging, and the environment (including the workplace) on the expression (or repression) of high sensitivity.Also, unlike previous books, this volume takes a broad perspective on outcomes related to being highly sensitive to shine a light on the non-trivial issue plaguing many HSPs: diminished quality of life, happiness, and well-being. As such, a major contribution of the second volume on the science of SPS, is its extensive description of scientifically-based techniques that might improve the quality of life for those with high SPS.Thus, this volume may appeal to a wide audience, including both HSPs and those in their social network (friends, partners, physicians, parents, educators, and clinicians) who wish to better understand SPS, those with the trait, and how to enhance well-being among the highly sensitive.

  • Alzheimer's Disease Research Guide

    Animal Models for Understanding Mechanisms and Medications
    • 1st Edition
    • Takaomi C. Saido
    • English
    Alzheimer's Disease Research Guide: Animal Models for Understanding Mechanisms and Medications provides researchers with a comprehensive guide, detailing every aspect of Alzheimer's Disease research, including chapters on neuroinflammation, immunotherapy, biomarkers, and animal modeling. This book begins with historical perspectives of both pathological chronology and pathological biochemistry in relation to Alzheimer’s disease. Other chapters review Amyloidogenic AB and Non-Amyloidogenic tau and Metabolism of AB major components to the research and understanding of Alzheimer’s research. The book concludes with specific treatment chapters including how to develop safe, effective, and inexpensive medications and the application of genome editing to the treatment of Familial Alzheimer's Disease.Written by world renowned expert in Alzheimer’s research, this book is a valuable resource for all researchers.

  • Redox Signaling in Wound Healing in Elderly Populations: Theoretical Basis, Part 1

    • 1st Edition
    • Volume 2
    • English
    Redox Signaling in Wound Healing in Elderly Populations: Theoretical Basis, Part 1 deals with wounds in different types and locations (diabetic, ischemic, post-operational) in subcellular and macro dimensions, examine their relationship with aging aim to target deteriorating redox signaling cascades, and will also focus on promising therapeutic approaches. Understanding the indication for the use of new therapeutics targeting the illuminated pathways in wound healing will help adjust treatment regimens befitting modern medicine. Ineffective redox adaptation and disseminated oxidative injury are the hallmarks of continuing oxidative stress. However, oxidative stress cannot be simply described as the imbalance between ROS formation and antioxidant defense capacity; it also covers impairment in redox sensing and signaling pathways. The term oxidative stress is an expression that is losing its use in modern redox biology. It is now an accepted fact that ROS cannot be described as an apparent enemy or friend. Its optimum level modulates signal transduction and stress responses by acting as a second messenger for redox-sensitive cascades. Redox-dependent second messengers are generated in subcellular locations according to specific rules and regulations. Their appearance depends on cellular needs in response to external and internal stimuli variations. A good understanding of the wound healing cascades, which deteriorate especially in advancing ages, is critical in developing the most appropriate approach. To understand the redox signaling mechanisms and healing cascades in wound healing, to pioneer new pharmacoactive drugs that can be developed based on these mechanisms, to reveal the deteriorating dynamics in the elderly patient group, and to propose new treatment methods suitable for the advanced age group.

  • Case-Based Practical Training of Colposcopy and Cervical Pathology

    With Diagrams and Images
    • 1st Edition
    • Nadereh Behtash + 5 more
    • English
    Case-Based Practical Training in Colposcopy and Cervical pathology: With Diagrams and Images is an illustrated reference to improve theoretical and practical knowledge to understand and perform colposcopy. Cervical cancer screening has advanced a great deal over the last century, and the medical field has come far in detect early pre-cancer and invasive cancer of the cervix though colposcopy and pathology. Anyone in the field of gynecology, pathology, and oncology will find this book useful to better understand the different levels of prevention, including vaccinations and screening and for students to correctly understand colposcopy and cervical pathology through real illustrated case studies. The book’s aim is for for prevention and treatment of anogenital and HPV related -diseases and supports the goal of the World Health Organization to cure cervical cancer by 2030.

  • Bio-organic Amendments for Heavy Metal Remediation

    Water, Soil and Plant Approaches and Technologies
    • 1st Edition
    • Allah Ditta + 3 more
    • English
    Bio-organic Amendments for Heavy Metal Remediation: Water, Soil and Plant Approaches and Technologies focuses on these core continuum media to explore remediation options using microbial, organic, and combined approaches. This volume in the Plant Biology, Sustainability and Climate Change series offers a comprehensive view of techniques and approaches for addressing contamination by heavy metals. It provides a comprehensive view of the challenge, with a focus on the bioremediation of heavy metals contamination using ecotechnological approaches for protecting the soil, water, and plant continuum.As anthropogenic activities increasingly negatively impact natural resources, there has been significant disturbance of the water, soil, and plant continuum due to the accumulation of heavy metals. The bioaccumulation of heavy metals in the food chain could pose life-threatening effects on plants as well as humans, and there is need to find effective and sustainable remediation options. The application of bio-organic amendments could serve as a sustainable solution to this problem.

  • Metabolomics for Personalized Vaccinology

    • 1st Edition
    • Mahbuba Rahman
    • English
    Metabolomics for Personalized Vaccinology provides insight into the importance of personalized vaccines in the clinical and research environments. It explores the development of personalized vaccines, which requires in-depth knowledge of the patient’s health status, particularly the immune system, and on metabolomics, the closest indicator of the disease phenotype. Specifically, the book provides an understanding of how metabolomics might be employed in personalized vaccinology and how the metabolic pathway of the host’s system is altered by vaccine administration.Over the past few years, researchers have published articles on personalized vaccines, but these are sparse. Therefore, compiling information on this topic gives the reader an overview of the progress of the field, despite being at its infancy.Metabolomics for Personalized Vaccinology is ideally suited for researchers and postgraduate students who are interested in clinical and nonclinical studies where metabolites are used for the identification of disease and therapeutic targets.

  • Essentials of Translational Pediatric Drug Development

    From Past Needs to Future Opportunities
    • 1st Edition
    • Elke Gasthuys + 3 more
    • English
    Essentials of Translational Pediatric Drug Development: From Past Needs to Future Opportunities provides integrated and up-to-date insights relevant for both translational researchers and clinicians active in the field of pediatric drug development. The book covers all key aspects from different stakeholder perspectives, providing a literature overview and careful reflection on state-of-the-art approaches. It will be an ideal guide for researchers in the field who are designing and performing high quality, innovative pediatric-adapted drug development by helping them define needs/challenges and possible solutions that advance and harmonize pediatric drug development.Despite the broad consensus that children merit the same quality of drug treatment as any other age group, children remain frequently neglected during drug research and development. Even with the adoption of multiple legislations addressing this problem, the lack of efficacy and safety data of marketed as well as newly developed drugs still remain in the pediatric population.

  • Quality Assurance Management

    A Comprehensive Overview of Real-World Applications for High Risk Specialties
    • 1st Edition
    • Gayathri De Lanerolle + 3 more
    • English
    Quality Assurance Management: A Comprehensive Overview of Real-World Applications for High Risk Specialties demonstrates how to best design and implement standard operating procedures (SOPs) to ensure protocol and regulation adherence. The book showcases similarities and differences between healthcare and academic quality assurance systems, resulting in counter-productivity and performance issues, in addition to regulatory inspection preparedness. It uses the processes and standards of the UK to demonstrate how to combine QA and research building into ‘building blocks’ that share a common pathway for effective project design, analysis and unbiased interpretation of collated data.This book fills a gap, providing original research in QA that especially focuses on specialist areas. It will be of use to research and clinical staff working in clinical research within healthcare, academia and industry.

  • Learning Deep Brain Stimulation Management through Clinical Cases

    • 1st Edition
    • Martijn Beudel
    • English
    Learning Deep Brain Stimulation Management through Clinical Cases reviews the clinical practice of applying deep brain stimulation (DBS) to patients with movement disorders. The book explores the cardinal aspects of applying DBS in diverse movement disorders based on patient’s needs. Every case answers all questions, providing case descriptions and step-by-step procedures for optimal replication. Every chapter includes a clinical decision support system (CDSS) depicted in flowcharts that can be used for reference. Deep Brain Stimulation (DBS) uses electrical stimulation to regulate electrical signals in neural circuits to and from identified areas in the brain to improve movement symptoms.The management of DBS in a movement disorders can be challenging, optimizing patient journeys and grasping all clinical aspects of the highly technological therapy. Hence, this book provides the informaiton necessary to embrace new breakthroughs.

  • Circuits, Signals, and Systems for Bioengineers

    A MATLAB-Based Introduction
    • 4th Edition
    • John Semmlow
    • English
    Circuits, Signals, and Systems for Bioengineers: A MATLAB-Based Introduction, Fourth Edition, guides the reader through the electrical engineering principles that can be applied to biological systems. It details the basic engineering concepts that underlie biomedical systems, medical devices, biocontrol, and biomedical signal analysis, providing a solid foundation for students in important bioengineering concepts. Fully revised and updated to better meet the needs of instructors and students, the fourth edition expands on concepts introduced in the previous edition through computational methods that allow students to explore operations, such as correlations, convolution, the Fourier transform, and the transfer function. New medical examples and applications are included throughout the text.

  • The Discovery of New Medicines in Academia

    • 1st Edition
    • Volume 100
    • English
    The Discovery of New Medicines in Academia, Volume 100 highlight examples of discoveries originating in academia that have been successfully translated into promising therapeutics that have advanced into clinical trials. Chapters in this release cover Design and Discovery of Itaconate prodrugs for Alopecia Areata, Hydroxyl-Dendrimer Delivery System for Neurological Disease, Development of allosteric modulators of G protein-coupled receptors for Psychiatric Disease, Targeting the constitutively active ERK1/2 signaling kinase for cancer, mRNA reprogramming of myeloid cells for tumor immunotherapy, Development of novel drugs targeting protein-protein interactions, and much more.Additional sections cover Neuro-steroids and analogs for the treatment of epilepsy, Development of inhibitors of eukaryotic translation, Discovery/developmen... of antiviral, anticancer and/or anti-inflammatory agents, Discovery of novel anti-infective agents, Targeting proliferating cell nuclear antigen (PCNA) for cancer, and Implementation and Evolution of Quantitative Systems Pharmacology to Patient Digital Twins and Biomimetic Twins.

  • Advances in Agronomy

    • 1st Edition
    • Volume 187
    • English
    Advances in Agronomy, Volume 187, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.

  • Targeted Genome Engineering via CRISPR/Cas9 in Plants

    • 1st Edition
    • Alvina Gul
    • English
    Targeted Genome Engineering via CRISPR/Cas9 in Plants provides in-depth insights into the use of the emerging “CRISPR/Cas9” technology for precise genome editing. This technology has revolutionized plant science research particularly for crop improvement owing to its simplicity and efficiency. The book provides a wide range of CRISPR/Cas9 gene editing techniques for a variety of plants. Chapters include the latest applications of CRISPR/Cas9 system in connection with abiotic stresses, biotic stresses, biofortification, yield improvement, disease modelling and prognosis and molecular diagnosis. Targeted Genome Engineering via CRISPR/Cas9 in Plants also evaluates various regulatory and ethical aspects that must be considered when implementing the CRISPR/Cas9 approach. This book is a valuable resource for professionals and researchers, as it provides effective CRISPR/Cas9-based strategies for sustainable agriculture and treatment of various diseases.

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 85
    • English
    Advances in Microbial Physiology, Volume 85 in this ongoing serial, highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Topics of interest in this update include The genetic basis of predation by myxobacteria, Vancomycin susceptibility and VISA in Staphylococcus aureus, Cytochrome bd-type oxidases and environmental stressors in microbial physiology, Bacterial heme-containing sensor proteins, Algal hemoglobins, Inter-species interactions in polymicrobial infections, Utilization of Low Methane Concentrations by Methanotrophs, and Role of sulfidogenic members of the gut microbiota in human disease.

  • The Neurophysiology of Silence (C): Creativity, Aesthetic Experience and Time

    • 1st Edition
    • Volume 287
    • English
    Neurophysiology of Silence: Consciousness and Self Awareness, Volume 284 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Hormones and Reproduction of Vertebrates, Volume 1

    Fishes
    • 2nd Edition
    • David O. Norris + 1 more
    • English
    Hormones and Reproduction of Vertebrates, Volume 1: Fishes is the first of five second-edition volumes representing a comprehensive and integrated overview of hormones and reproduction in fishes, amphibians, reptiles, birds, and mammals. The book includes coverage of endocrinology, neuroendocrinology, physiology, behavior, and anatomy of fish reproduction. It provides a broad treatment of the roles of pituitary, thyroid, adrenal, and gonadal hormones in all aspects of reproduction, as well as descriptions of major life history events. New to this edition is a concluding assessment of the effect of environmental influences on fishes.Initial chapters in this book broadly examine sex determination, reproductive neuroendocrinology, stress, and hormonal regulation as they relate to testicular and ovarian development and function. Subsequent chapters examine hormones and reproduction of specific taxa, especially teleosts, with additional coverage of reproductive cycles of agnathan, chondrichthyan, and sarcopterygian fishes. The book concludes with an examination of the environmental influences on hormones and reproduction of fishes, including endocrine-disrupting chemicals, microplastic particles, and climate change.

  • Biophysical Approaches for the Study of Membrane Structure Part B

    • 1st Edition
    • Volume 701
    • English
    Biophysical Approaches for the Study of Membrane Structure, Part B, Volume 701 explores lipid membrane asymmetry and lateral heterogeneity. A burst of recent research has shown that bilayers whose leaflets differ in their physical properties—such as composition, phase state, or lateral stress—exhibit many fascinating new characteristics, but also pose a host of challenges related to their creation, characterization, simulation, and theoretical description. Chapters in this new release include Characterization of domain formation in complex membranes: Analyzing the bending modulus from simulations of complex membranes, The density-threshold affinity: Calculating lipid binding affinities from unbiased Coarse-Grain Molecular Dynamics simulations, and much more.Additional sections cover Uncertainty quantification for trans-membrane stresses and moments from simulation, Using molecular dynamics simulations to generate small-angle scattering curves and cryo-EM images of proteoliposomes, Binary Bilayer Simulations for Partitioning Within Membranes, Modeling Asymmetric Cell Membranes at All-atom Resolution, Multiscale remodeling of biomembranes and vesicles, Building complex membranes with Martini 3, Predicting lipid sorting in curved bilayer membranes, Simulating asymmetric membranes using P21 periodic boundary conditions, and many other interesting topics.

  • Cannabidiol in Neurology and Psychiatry

    • 1st Edition
    • Volume 177
    • English
    Cannabidiol in Neurology and Psychiatry, Volume 177 in the International Review in Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on topic such as Historical perspective on the therapeutic potential of cannabidiol, Cannabidiol: pharmacodynamics pharmacokinetic, Cannabidiol and Alzheimer’s disease, Cannabidiol on anxiety disorders, Cannabidiol on psychosis, Cannabidiol on autism spectrum disorders, Cannabidiol in Epilepsy, Cannabidiol in Ischemia/stroke, Cannabidiol in Depression, Cannabidiol and Abuse of drugs, and much more.Additional chapters cover Cannabidiol in fear response and PTSD, Cannabidiol and Pain. and Cannabidiol and Parkinson’s disease.

  • Blood-Brain Barrier

    • 1st Edition
    • Volume 126
    • English
    Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

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