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    • Novel Approaches to Colorectal Cancer

      • 1st Edition
      • Volume 151
      • June 18, 2021
      • English
      • Hardback
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      • eBook
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      Novel Approaches to Colorectal Cancer, Volume 151 in the Advances in Cancer Research series, is composed of 11 reviews covering state-of-the-art research relating to the etiology, diagnosis, prevention and treatment of colorectal cancer. The book's chapters were written by recognized experts in the field, and include sections on molecular biomarkers in diagnosis and therapy, the interplay of diet, lifestyle, and the microbiome, early-age onset disease, mutational signature analysis, challenges in early detection, immunotherapy, organoid technology, the role of epigenetic alterations, disparities in minority populations, field carcinogenesis, and cancer as an evolutionary process. Each of these topics provides novel insights and concepts on various aspects of the nature of colorectal cancer, offering new opportunities for the management of a major source of cancer incidence and mortality.

    • Recombinant Protein Expression: Prokaryotic hosts and cell-free systems

      • 1st Edition
      • Volume 659
      • October 28, 2021
      • English
      • Hardback
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      • eBook
        9 7 8 0 3 2 3 9 0 1 4 7 5
      Recombinant Protein Expression, Part A, Volume 659 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on Multiplexed analysis protein: Protein interactions of polypeptides translated in Leishmania cell-free system, MultiBac system and its applications, performance and recent, Production of antibodies in Shuffle, Designing hybrid-promoter architectures by engineering cis-acting DNA sites to enhance transcription in yeast, Designing hybrid-promoter architectures by engineering cis-acting DNA sites to deregulate transcription in yeast, Antibody or protein-based vaccine production in plants, Cell-free protein synthesis, Plant-based expression of biologic drugs, and much more. Additional sections cover the Use of native mass spectrometry to guide detergent-based rescue of non-native oligomerization by recombinant proteins, Advancing overexpression and purification of recombinant proteins by pilot optimization through tandem affinity-buffer exchange chromatography online with native mass spectrometry, Method for High-Efficiency Fed-batch cultures of recombinant Escherichia coli, Method to transfer Chinese hamster ovary (CHO) shake flask experiments to the ambr® 250, and Expression of recombinant antibodies in Leishmania tarentolae.

    • A Tribute to Paul Greengard (1925-2019)

      • 1st Edition
      • Volume 90
      • March 2, 2021
      • English
      • Hardback
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      • eBook
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      A Tribute to Paul Greengard, Volume 90, the latest release in the Advances in Pharmacology series presents a variety of chapters from the best authors in the field, with this release presenting a tribute to Paul Greengard.

    • Methods in Microbiology

      • 1st Edition
      • Volume 49
      • July 7, 2021
      • English
      • Hardback
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      • eBook
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      The book Methods in Silkworm Microbiology is the first ever publication that provides in-depth reviews on the latest progresses about silkworm –pathogen interactions, diseases and management practices for sustainable development of sericulture. Different molecular and immunodiagnostic methods for the detection of pathogens have been comprehensively addressed. Most recent advancements on the role of Micro RNAs in silkworm and pathogen interactions are provided with suitable illustrations. Recent technological advances and emerging trends in exploring silkworm gut microbial communities towards translation research, particularly to understand microbiome functions have been highlighted. Information on various immune mechanisms of silkworm against invading pathogens is summarized. The book further highlights the silkworm gut microbiota as a potential source for biotechnological applications.

    • Prof. of Drug Substances, Excipients and Related Methodology

      • 1st Edition
      • Volume 46
      • January 16, 2021
      • Abdulrahman Al-Majed
      • English
      • Hardback
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      • eBook
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      Profiles of Drug Substances, Excipients, and Related Methodology, Volume 46 contains comprehensive profiles of five drug compounds: Darunavir, Bisoprolol, Betaxolol, Rabeprazole and Irbesartan. In addition, the work contains a chapter reviewing Bioassay Methods and Their Applications in Herbal Drug Research. The comprehensive reviews in the book cover all aspects of drug development and the formulation of drugs, helping readers understand how the drug development community remains essential to all phases of pharmaceutical development. In addition, this work answers why such profiles are of immeasurable importance to workers in the field. The scope of the Profiles series encompasses review articles and database compilations that fall within one or more of the following five broad categories: Physical Profiles of Drug Substances and Excipients, Analytical Profiles of Drug Substances and Excipients, ADME Profiles of Drug Substances and Excipients, Methodology Related to the Characterization of Drug Substances and Excipients, and Methods of Chemical Synthesis.

    • Mechanisms and Therapy of Liver Cancer

      • 1st Edition
      • Volume 149
      • February 10, 2021
      • English
      • Hardback
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      • eBook
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      Mechanisms and Therapy of Liver Cancer, Volume 149, presents the latest information on the incidence and mortality of liver cancer research and how it has gained significant momentum because of its direct causative association with obesity-induced fatty liver disease. The literature on liver cancer is moving fast with exciting, novel findings, providing new insights reflected in the following updated chapters: Introduction and molecular classification of HCC, Signaling Pathways in Liver Cancer, HCV and HCC, NASH and HCC, Microbiome and Metabolic Abnormalities in HCC, Systemic Therapy of Liver Cancer, Immunotherapy of Liver Cancer, and Desmoplastic Tumor Microenvironment and Intrahepatic Cholangiocarcinoma Progression: Mechanisms and Therapeutic Implications.

    • Encyclopedia of Dairy Sciences

      • 3rd Edition
      • September 22, 2021
      • Paul L.H. McSweeney + 1 more
      • English
      • Hardback
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      • eBook
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      Dairy science includes the study of milk and milk-derived food products, examining the biological, chemical, physical, and microbiological aspects of milk itself, as well as the technological (processing) aspects of the transformation of milk into its various consumer products, including beverages, fermented products, concentrated and dried products, butter and ice cream. This encyclopedia includes information on the possible impact of genetic modification of dairy animals, safety concerns of raw milk and raw milk products, peptides in milk, dairy-based allergies, packaging and shelf-life and other topics of importance and interest to those in dairy research and industry. The Encyclopedia of Dairy Sciences, Five Volume Set is the only work available that covers in detail the entirety of dairy science, from husbandry of dairy animals, milk production, through the processing of milk into a myriad of dairy products and ingredients, to the effect of dairy foods on human health. The third edition of Encyclopedia of Dairy Sciences will retain the split that characterized the earlier editions - one-third primary production, two-thirds dairy food. Unlike earlier editions, in which articles were arranged in alphabetical order by topic, this edition will be optimally organized into 9 coherent sections. This new edition contains 500 articles, the vast majority of which has been significantly revised or is completely new. Only 40 chapters have been retained from the earlier edition as they cover basic science areas still relevant and important today. All articles have been reviewed by specialists in their area.

    • Eutectic Solvents and Stress in Plants

      • 1st Edition
      • Volume 97
      • January 14, 2021
      • English
      • Hardback
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      • eBook
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      Eutectic Solvents and Stress in Plants, Volume 97 in the Advances in Botanical Research series, highlights new advances in the field, with this new volume presenting interesting chapters surrounding NADES: from simple systems to complex colloidal mixtures, DES nanostructures with water, micelle and DES interaction, Dissolving proteins protein physics, Enzyme reactions in NADES, Protection against oxidation of metabolites, stability food, DES for pharmaceutical preparations, Cosmetics, Metabolons and bio-condensates: the essence of plant plasticity and the key elements in development of green production systems, Immediate in the whole plant during extreme conditions metabolomics, NADES in sees spores, and much more.

    • Chemoarchitectonic Atlas of the Rat Brain

      • 3rd Edition
      • November 18, 2021
      • George Paxinos + 3 more
      • English
      • Hardback
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      • eBook
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      • eBook
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      The complement to The Rat Brain in Stereotaxic Coordinates, Chemoarchitectonic Atlas of the Rat Brain, Third Edition, features a single brain series of high-quality plates stained with eight different markers, extensively annotated and labelled throughout. Plates from the previous edition of Chemoarchitectonic Atlas of the Rat Brain have been re-scanned at high resolution and are shown in color. Labeled structures have been revised, corrected, and updated, providing users with a streamlined, up-to-date, and highly accurate compendium of chemical markers. Researchers with a need to understand the detailed organization of the rat brain as well as structure/function relationships will need this atlas and its array of stains.

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