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Books in Life sciences

  • The Vasculome

    From Many, One
    • 1st Edition
    • June 11, 2022
    • Zorina S. Galis
    • English
    The Vasculome: From Many, One introduces the fundamental bases of the “unity in diversity” of the Vasculome, from the coming together of various cell lineages during development, to its deceptively simple solution for architectural design: the efficient interplay of a few types of building blocks supporting key similar functions throughout the body and their highly specialized functional local variations. Specific examples are included to illustrate how the Vasculome is integral to the function and malfunction of different organs, such as the brain or the kidney. Each section is preceded by an introductory summary that will give a high level unified view of the key concepts illustrated in the various chapters in that section. Zorina Galis' The Vasculome was named a finalist in the Clinical Medicine category of the American Association of Publishers’ 2023 PROSE Awards.
  • Methods of Mathematical Modelling

    Infectious Diseases
    • 1st Edition
    • June 10, 2022
    • Harendra Singh + 2 more
    • English
    Methods of Mathematical Modeling: Infectious Diseases presents computational methods related to biological systems and their numerical treatment via mathematical tools and techniques. Edited by renowned experts in the field, Dr. Hari Mohan Srivastava, Dr. Dumitru Baleanu, and Dr. Harendra Singh, the book examines advanced numerical methods to provide global solutions for biological models. These results are important for medical professionals, biomedical engineers, mathematicians, scientists and researchers working on biological models with real-life applications. The authors deal with methods as well as applications, including stability analysis of biological models, bifurcation scenarios, chaotic dynamics, and non-linear differential equations arising in biology. The book focuses primarily on infectious disease modeling and computational modeling of other real-world medical issues, including COVID-19, smoking, cancer and diabetes. The book provides the solution of these models so as to provide actual remedies.
  • Genomic Medicine Skills and Competencies

    • 1st Edition
    • June 10, 2022
    • Dhavendra Kumar
    • English
    Genomic Medicine Skills and Competencies discusses core and practical aspects of genetic and genomic education and training for medical field. Many aspects of genomic applications in science, biotechnology, clinical medicine and healthcare require core and specialist knowledge, skills development and competencies for carrying out diverse tasks. Several knowledge-based courses and opportunities for skills and competencies development and assessment are now available and the main required subjects are discussed in this volume. The book focuses on all major aspects of genetic and genomic education training that are currently offered and evaluated and is a valuable resource for researchers, clinicians, physicians, nurses, genetic counselors, bioinformatics technicians, and other professionals who are interested in learning more about such promising field.
  • Applied Environmental Metabolomics

    Community Insights and Guidance from the Field
    • 1st Edition
    • June 9, 2022
    • David J. Beale + 3 more
    • English
    Applied Environmental Metabolomics: Community Insights and Guidance from the Field brings together contributions from global experts who have helped to define and develop the exciting and rapid advances that are taking place in the field of environmental metabolomics. This book is aimed at expert users, students, researchers, and academics in metabolomics and systems biology. It not only demonstrates the best practice in experimental design but also provides insight into state-of-the-art instrumentation and the depth of analysis one can expect to get by using various sampling, chromatographic, mass spectrometric, and nuclear magnetic resonance (NMR) techniques. Common experimental and technical pitfalls are also highlighted. This book provides a unique insight into the world of environmental metabolomics and will help the practicing scientist avoid repeating similar costly mistakes, steering them efficiently toward the generation of high-quality data and high-impact publications.
  • Macrophages in the Human Body

    A Tissue Level Approach
    • 1st Edition
    • June 8, 2022
    • Niels Olson Saraiva Camara + 1 more
    • English
    Through recent research, there has been a significant number of findings involving the biology of macrophages. Beyond the 1st line of defense, macrophages have several specific characteristics across different tissues, organs, and systems. Macrophages comprehend a heterogeneous phagocytic population with wide range phenotypes, and tissue-specific functions, such as bone resorption, extracellular matrix production, red blood cells and bacteria removal, among others. Through innate immune receptors macrophages can modulate several pathways that culminate in the production of various types of inflammatory mediators such as chemokines, cytokines, oxygen reactive species, and lipid mediators which ultimately altered the behavior of other cells. Moreover, environment signals modify and induce metabolic reprograming that it alters phenotype and functions.Macrophage... in the Human Body: A Tissue Level Approach presents a current overview of the diversity of macrophages across multiple human body systems, their phenotype, function and metabolic characteristics. It covers translational aspects where there is research support to indicate the therapeutic potential.
  • Comprehensive Pharmacology

    • 1st Edition
    • June 8, 2022
    • Terry P. Kenakin
    • English
    Comprehensive Pharmacology, Seven Volume Set is organized into twelve sections that explore therapeutic areas, with a total of 320 comprehensive articles and 6,800 pages of important findings. Sections contain highly detailed coverage of information that has been overseen by an editorial board made up of well-respected, field leading experts. The content in this book offers readers an in-depth and easily accessible reference work on every aspect of pharmacological research surrounding the pharmacology of all therapeutic applications of drugs, their mechanism of action and their therapeutic values. These elements are essential as drugs are almost never tested and developed in the actual therapeutic system, but rather in test systems from which parameters must be determined to predict activity in systems of varying ambient physiology. As different technologies rapidly evolve, there is an ever-increasing level of knowledge about the pharmacology of known drugs, along with increasing capability to utilize pharmacological systems to predict new drug activity, all of which must be communicated to professionals in varying fields.
  • The ERAS® Society Handbook for Obstetrics & Gynecology

    • 1st Edition
    • June 8, 2022
    • Gregg Nelson + 4 more
    • English
    The ERAS® Society Handbook for Obstetrics & Gynecology covers all aspects of enhanced recovery care for disciplines of general gynecology, gynecologic oncology, urogynecology and obstetrical surgery. Written by renowned experts in the field, chapters discuss foundational knowledge on ERAS and provide specific worked examples, ERAS order sets, and practical implementation tools. This book is an indispensable resource to researchers interested in ERAS, but it is also ideal for anesthesiologists, gynecologists and obstetricians interested in initiating an ERAS program. Enhanced Recovery After Surgery (ERAS) is a global surgical quality improvement initiative that originated in colorectal surgery and has now spread to numerous other disciplines, including gynecology (benign and malignant) and obstetrics (caesarean delivery). ERAS is associated with improvements in clinical outcomes (reduction in length of hospital stay, complications, readmissions), cost savings for the healthcare system, and patient satisfaction, hence the addition of this comprehensive resource on the topics is a welcomed addition to the available literature.
  • Sustainable Crop Productivity and Quality under Climate Change

    Responses of Crop Plants to Climate Change
    • 1st Edition
    • June 7, 2022
    • Fulai Liu + 5 more
    • English
    Sustainable Crop Productivity and Quality under Climate Change: Responses of Crop Plants to Climate Change explores the physiological, biochemical, and molecular basis of the responses of major crop plants to a range of climate change scenarios. From the development of climate-resilient crop varieties which lead to enhanced crop productivity and quality to better utilization of natural resources to ensure food security through modern breeding techniques, it presents insights into improving yield while securing the environment. Understanding the impact of climate on crop quality and production is a key challenge of crop science. Predicted increases in climate variability necessitate crop varieties with intrinsic resilience to cooccurring abiotic stresses such as heat, drought, and flooding in a future climate of elevated CO2. This book presents a much-needed mechanistic understanding of the interactions between multiple stress responses of plants that is required to identify and take advantage of acclimation traits in major crop species as a prerequisite for securing robust yield and good quality. This book is an excellent reference for crop and agricultural scientists, plant scientists, and researchers working on crop plant ecophysiology/stress physiology and future crop production.
  • Cancer Biomarkers: Clinical Aspects and Laboratory Determination

    • 1st Edition
    • June 7, 2022
    • Lakshmi V. Ramanathan + 2 more
    • English
    Cancer Biomarkers: Clinical Aspects and Laboratory Determination provides a comprehensive overview of current biomarkers for cancer detection, monitoring and recurrence, focusing on emerging technologies, impacts on the field, and selected biomarkers currently used in clinical practice. The content highlights current laboratory tests used in the management of adult and pediatric cancer patients. In addition, it investigates the role of Circulating Tumor Cells and circulating tumor DNA as biomarkers in cancer management as well as cytokines in monitoring response to CAR T therapies. This title is a perfect reference for clinical pathologists, laboratory scientists, medical technologists, physicians specializing in oncology, internal medicine, family practice and transplant medicine, resident physicians, medical students, nurse practitioners and clinical chemists.
  • Advances in Cardiovascular Technology

    New Devices and Concepts
    • 1st Edition
    • June 5, 2022
    • Jamshid Karimov + 2 more
    • English
    Advances in Cardiovascular Technology: New Devices and Concepts is a comprehensive reference for cardiovascular devices of all types. For engineers, this book provides a basic understanding of underlying pathologies and their prevalence/incidence... It also covers what devices are available, how they are clinically used, and their impact on pathophysiology. In addition, the book presents the constraints imposed on device design and manufacture by the environment in which it is used (e.g., exposure to tissues within the body, blood in particular) and the primary requirements for each specific type of device, including its durability and resistance to fatigue. For clinicians, this book contains information on primary engineering challenges, the types of devices available, their advantages and disadvantages, and the (current and emerging) tools and materials available to device designers.