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Elsevier

Books in Life sciences

  • Essentials of Medical Coordination in Complex Humanitarian Emergencies

    • 1st Edition
    • Joanna Kotcher
    • English
    Essentials of Public Health and Medical Coordination in Complex Humanitarian Emergencies provides a practical overview for health coordinators in assessing, coordinating, and implementing medical and public health responses in disaster and conflict environments. The book aims to achieve this in two parts. Part one covers foundational information such as the role of the coordinator; project assessment and start-up; standards, protocols, and guidelines; project strategy and accountability; and basic epidemiological measurements and tools. Part two goes on to discuss the implementation of programs and services like nutrition, mental health and psychosocial support (MHPSS), management of chronic disease, community health promotion, sexual and reproductive health, health information systems and disease surveillance. A health coordinator in the field is required to quickly assess the needs of a population in a humanitarian emergency, initiate start-up procedures, and coordinate the response over a period of months or longer. The efficiency and effectiveness of this process depends on the experience, knowledge, and skills of the coordinator, Essentials of Public Health and Medical Coordination in Complex Humanitarian Emergencies is a resource for those in the medical, public health, and international humanitarian aid sectors who care about the health of populations at risk and is written by an author who has coordinated emergency response in conflict environments in Kosovo, Central Asia (Tajikistan), Afghanistan, Darfur, Gaza and the OPT, Somaliland, Syria, and Iraq.

  • Advanced Nanofiber Technology in Cancer Management

    • 1st Edition
    • Goutam Rath + 2 more
    • English
    Advanced Nanofiber Technology in Cancer Management presents a comprehensive exploration of nanofiber-based systems for cancer therapy and diagnostics. It bridges pharmaceutical sciences, nanotechnology, and oncology to address the challenges of targeted drug delivery and systemic toxicity. The book covers biopolymer, peptide, carbon, and metal nanofibers, detailing their fabrication, characterization, and application in chemotherapy, immunotherapy, gene therapy, and photothermal treatment. It also explores diagnostic innovations such as biosensors and imaging-guided systems, alongside AI and 3D printing in nanofiber development. This volume benefits researchers, clinicians, and pharmaceutical developers by offering translational insights, regulatory perspectives, and real-world case studies. It supports informed decision-making in cancer management and product development.

  • Tropical Fern Biology and Evolution

    • 1st Edition
    • Daniele Cicuzza + 2 more
    • English
    Tropical Fern Biology and Evolution is the first reference to focus on this important tropical flora. While other resources highlight the plants of temperate regions, this book focuses specifically on those of the tropics, where important insights have been discovered about phylogenetic relationship between several pteridophyte and lycophyte phylogeny, ecology and physiology. Ferns and lycophytes are vital elements of tropical ecosystems. They thrive in various environments, from the shaded, humid floors of terrestrial forests to the canopy, where epiphytic species have adapted to harsh ecological conditions. In regions of the tropics that have been impacted by human activity, ferns are crucial for colonizing extensive areas and preventing soil erosion. However, they can also hinder forest regeneration in certain contexts. Gaining insight into the structure, growth, and effects of these plants is essential for tackling the challenges and leveraging the benefits they present. Based on the latest research, Tropical Fern Biology and Evolution discusses their traits and community assemblies in the humid tropics and presents potential application uses for their phylogenetic information. Students and researchers will find this foundational information valuable as both an introductory guide to these tropical ferns and their characteristics, and as inspiration for further research and development of their potential in addressing environmental issues.

  • Emerging Technologies in Bioengineering for Oncology

    Fundamentals, Research, and Future Prospects
    • 1st Edition
    • Saikat Das + 2 more
    • English
    Emerging Technologies in Bioengineering for Oncology: Fundamentals, Research, and Future Prospects explores the integration of engineering, biology, and medicine to tackle challenges in developing innovative tools for cancer diagnosis and treatment. This comprehensive resource addresses the evolving landscape of bioengineering in oncology, highlighting the intersection of various disciplines to drive advancements in diagnostic and therapeutic approaches. The book explores a range of cutting-edge technologies such as lab-on-chip devices, wearable biosensors, 3D bioprinting, and targeted nanomedicine, offering promising avenues for enhanced diagnostic precision, treatment effectiveness, and personalized healthcare.Geared towards medical students and professionals, the book provides detailed insights into the latest developments, practical applications, and future research directions in the field. By offering a deep dive into the realm of bioengineering for oncology, it serves as a valuable asset for those seeking to advance cancer care through interdisciplinary collaboration and innovation.

  • Edible Electronics

    Principles, Fundamentals, and Applications in Smart Food Packaging and Biomedical Innovations
    • 1st Edition
    • Arun Kumar Gupta + 1 more
    • English
    Edible Electronics: Principles, Fundamentals, and Applications in Smart Food Packaging and Biomedical Innovations addresses the growing global demand for sustainable technologies and environmentally responsible solutions. Conventional electronic devices often rely on toxic, non-biodegradable materials that contribute significantly to electronic waste, posing environmental and health risks, particularly in developing regions and areas with limited waste management systems. By introducing the concept of edible electronics and emphasizing the use of biocompatible and biodegradable materials, this book highlights innovative approaches to reducing electronic waste and mitigating the effects of environmental degradation. It advocates the adoption of sustainable technological practices that can support the needs of an expanding global population while promoting both human and environmental well-being.The book provides a comprehensive exploration of edible electronic materials, including conductors, dielectrics, and semiconductors, and examines their integration into functional electronic systems. It discusses the development of sensors for both in-body and external applications, along with energy storage and supply systems such as batteries and supercapacitors. In addition, the text covers advanced communication methods, including radio-frequency, intra-body, and optical technologies, demonstrating the broad potential of edible electronics across food packaging, healthcare, and biomedical applications.A detailed overview of fabrication techniques is also presented, including deposition, filming, patterning, printing, and carbonization processes. These methods are examined with an emphasis on ensuring the safety, performance, and reliability of edible electronic systems. Furthermore, the book explores regulatory considerations, safety standards, and environmental impacts associated with the development and deployment of such technologies.

  • Endoscopic Ultrasound in Pancreatic Diseases

    Best Practices and Recent Innovations in Technology and Techniques
    • 1st Edition
    • Masayuki Kitano
    • English
    In Endoscopic Ultrasound in Pancreatic Diseases: Best Practices and Recent Innovations in Technology and Techniques, leading experts share their insights, best practices, and the latest technological innovations revolutionizing the approach to pancreatic diseases. This practical reference provides step-by-step guidance, case presentations, and detailed images and procedures on advanced techniques in diagnosis and treatment with endoscopic ultrasound for pancreatic diseases.Organized into four sections, this book reviews the latest advances in endoscopic ultrasound equipment, techniques, complications, scanning methods, microbubbles and contrast harmonic imaging, elastography, fine needle tissue acquisition, and classification and safety management of interventional endoscopic ultrasound. Tumor detection, characterization, and diagnosis are reviewed, and pancreatic diseases treatment and intervention methods are covered extensively. The book concludes with the examination of groundbreaking methods and discussion of education and future directions. Endoscopic Ultrasound in Pancreatic Diseases: Best Practices and Recent Innovations in Technology and Techniques fully equips endoscopists with the most recent developments in endoscopic ultrasound and is a vital resource for navigating the evolving landscape, enabling practitioners to excel in advanced clinical practices and contribute to the field’s growth.

  • An Essential Guide to Radiation Dosimetry for Medical Applications

    Principles, Technologies, and Clinical Applications
    • 1st Edition
    • Jayachandran Venkatesan + 1 more
    • English
    An Essential Guide to Radiation Dosimetry for Medical Applications: Principles, Technologies, and Clinical Applications provides a comprehensive overview of the fundamental concepts, advanced methodologies, and emerging technologies in radiation dosimetry. This book serves as an essential resource for researchers, clinicians, and students involved in cancer research, bioinformatics, medical physics, radiology, material scientists and radiation therapy, offering in-depth insights into both theoretical principles and practical applications. The content covers core topics such as radiation interactions, dosimetry materials, and simulation techniques, alongside clinical and diagnostic applications.In addition, it also explores innovative approaches like artificial intelligence, nanodosimetry, and quality assurance, ensuring readers stay current with technological advancements. This book benefits the academic audience by enhancing their knowledge of dosimetry science and fostering the development of safer, more effective radiation practices. It supports education, research, and clinical decision-making, ultimately advancing the field of radiation physics and improving patient outcomes.

  • Artificial Intelligence Based Primary Care

    Artificial Intelligence and Human Cognition in General Practice and Family Medicine
    • 1st Edition
    • Anthony C. Chang + 5 more
    • English
    Artificial Intelligence Based Primary Care: Artificial Intelligence and Human Cognition in General Practice and Family Medicine provides a comprehensive look into the integration of artificial intelligence within primary care. This book aims to bridge the gap between data scientists and primary care clinicians by presenting potential AI applications, implementation challenges, and real-world clinical scenarios in an accessible manner. Comprised of 5 sections and 20 chapters, it offers both theoretical insights and practical guidance for family medicine practitioners.Additi... the book includes a chapter dedicated to a day in the life of a General Practitioner, showcasing the practical impact of AI. It also features an extra compendium listing the Top 100 articles and best books on Artificial Intelligence. This resource is invaluable for academics, researchers, and clinicians eager to expand their knowledge in this emerging field.

  • Leveraging AI and ML in Cardiovascular Diagnosis and Management

    • 1st Edition
    • Rosaline Mishra + 3 more
    • English
    Leveraging AI and ML in Cardiovascular Diagnosis and Management examines how artificial intelligence and machine learning transform cardiovascular care. It gathers chapters from leading researchers to bridge clinical practice with cutting-edge analytics, imaging, and decision support. The volume details core topics across the field, including fundamentals of AI/ML, AI-driven cardiovascular imaging, predictive analytics for risk stratification, heart failure management, arrhythmia detection, wearable-enabled monitoring, and the integration of multi-omics with clinical data. It also addresses neurocardiology, clinical decision support systems, ethics, and regulatory considerations, all framed for cardiovascular scientists and clinicians. For academics, clinicians, and educators, the book offers actionable workflows, a cohesive framework for translating AI and ML advances into improved diagnosis, treatment personalization, and patient outcomes across diverse populations.

  • Robotics and Artificial Intelligence in Neuromuscular Performance

    Assessment, Training, Injury Prevention, and Return to Play in Athletes
    • 1st Edition
    • Wissem Dhahbi + 1 more
    • English
    Athletic performance depends on technologies that can measure, model, and guide neuromuscular function across the complete athlete lifecycle. Robotics and Artificial Intelligence in Neuromuscular Performance provides an evidence-based framework for applying robotics, artificial intelligence, computer vision, wearable sensing, virtual reality, and biofeedback to assessment, training, injury prevention, rehabilitation, and return-to-play decision-making. Organized across 18 chapters, the book connects neuromuscular physiology with intelligent athlete systems, progressing from foundational concepts in computational biomechanics and robotic dynamometry to applied protocols for training load management, injury risk prediction, exoskeletal resistance training, smart rehabilitation, and AI-enhanced return-to-play clearance. Written for sports scientists, clinicians, physiotherapists, athletic trainers, strength and conditioning professionals, biomechanics researchers, and technology developers, it equips readers to evaluate rapidly expanding sports technologies with scientific rigor rather than assuming that innovation is inherently beneficial. Each chapter addresses validation status, measurement error, algorithmic limitations, data governance, and ethical risk, translating research evidence into criteria practitioners can apply directly. The AICICA framework, six implementation checklists, and integrated case studies extend the book beyond synthesis into practical guidance for responsible technology adoption in elite, clinical, and research settings.

  • Hereditary Syndromes Associated with Endocrine Tumors

    • 1st Edition
    • Volume 134
    • English
    Volume 134, Hereditary Syndromes Associated with Endocrine Tumors, provides a comprehensive and up-to-date overview of the genetic, molecular, clinical, diagnostic, and therapeutic aspects of inherited endocrine neoplasia syndromes. Over the past two decades, remarkable advances in genomics, molecular diagnostics, and precision medicine have transformed the understanding and management of hereditary endocrine tumor syndromes, enabling earlier diagnosis, individualized surveillance strategies, targeted therapies, and improved patient outcomes. This volume brings together contributions from internationally recognized experts to review the current state of knowledge on both well-established and emerging hereditary syndromes affecting the endocrine system. The chapters cover the genetic basis, genotype–phenotype correlations, clinical manifestations, screening recommendations, multidisciplinary management, and future therapeutic perspectives for syndromes predisposing to tumors of the adrenal glands, pituitary, thyroid, parathyroid, pancreas, and neuroendocrine tissues. Special emphasis is placed on recent discoveries in cancer predisposition genes, advances in molecular pathology, the integration of next-generation sequencing into clinical practice, and the implications of hereditary cancer syndromes for patients and their families.

  • Advanced Ultrasound with Imaging Correlations of Diffuse Liver Diseases

    • 1st Edition
    • Riccardo De Robertis
    • English
    Advanced Ultrasound with Imaging Correlations of Diffuse Liver Diseases addresses the critical need for detailed comparisons between advanced ultrasound (US) techniques and CT/MRI findings in the evaluation of liver diseases. While many books exist, few provide the in-depth analysis and practical guidelines necessary for accurate diagnosis and effective treatment planning. This book fills that gap, offering a multiparametric approach to the assessment of fibrotic and steatotic liver diseases. Inside, readers will find essential topics such as indications for liver US in diffuse liver diseases, advanced Ultrasound techniques for assessing liver fibrosis and steatosis, and the correlation between US, CT, and MRI findings.Key chapters cover the basics of liver ultrasound, conventional Doppler and microvascular flow imaging, ultrasound elastography, and the quantification of liver steatosis. Additionally, the book explores cutting-edge topics like artificial intelligence in liver ultrasound and the application of US in pediatric patients. Contributions from leading experts in the field ensure that each chapter provides valuable insights and practical advice. This is an indispensable resource for scientists, researchers, and clinicians alike. It offers clear guidelines on performing liver ultrasounds, understanding and interpreting results, and making informed comparisons with CT and MRI findings.

  • Starch-Based Edible Films and Coatings in Food Applications

    Innovations, Challenges, and Limitations
    • 1st Edition
    • Seid Reza Falsafi + 2 more
    • English
    Starch-Based Edible Films and Coatings in Food Applications: Innovations, Challenges, and Limitations addresses the urgent need for sustainable packaging solutions in the food industry. This book targets the information needs and daily challenges faced by college and postgraduate students, university scholars, researchers, food scientists, and industry professionals working with starch-based edible films and coatings. It provides a comprehensive overview of the latest innovations, current limitations, and ongoing challenges, supporting both academic research and practical industrial applications. The book is structured into four main sections. Section I covers the production of starch-based edible films, detailing native and modified starches, preparation mechanisms, and factors influencing film properties, as well as active, intelligent, and reinforced films. Section II presents recent applications in preserving fresh produce, animal products, and processed foods. Section III reviews current and advanced analytical techniques for characterizing these films. Section IV examines cutting-edge innovations, including nanotechnology and 3D printing, and discusses existing limitations and future challenges.Starch-Ba... Edible Films and Coatings in Food Applications: Innovations, Challenges, and Limitations is a valuable resource for graduate students, researchers, and food technologists. It offers essential knowledge on manufacturing, properties, safety, and market trends, facilitating the development of innovative and sustainable food packaging solutions.

  • Diet as Complementary Treatment to Cancer Prevention and Therapy

    • 1st Edition
    • Michael N.A. Eskin + 2 more
    • English
    Diet as Complementary Treatment to Cancer Prevention and Therapy explores the role of nutrition in the prevention and treatment of cancer. The book features in-depth chapters on various cancers including liver, cervical, thyroid, esophageal, pancreatic, and oral while detailing specific dietary strategies that may mitigate risk and support therapeutic efficacy. Additionally, it addresses the significant influence of the human microbiome on cancer dynamics and highlights the promising field of metabolomics as it pertains to future cancer research. Contributions from leading experts across the fields of food science, nutrition, pharmacology, and cancer research provide current and practical applications.This comprehensive resource equips healthcare professionals with the knowledge necessary to incorporate dietary considerations into cancer prevention and treatment protocols effectively.

  • Twin-to-Twin Transfusion Syndrome (TTTS)

    • 1st Edition
    • Michael W. Bebbington + 1 more
    • English
    Twin-to-Twin Transfusion Syndrome (TTTS) is a novel and comprehensive reference to understanding the pathophysiology of this condition, along with the latest diagnostic techniques and criteria for accurate identification, its treatment and management, and strategies for effective management and care. Beyond medical aspects, the book addresses the emotional and practical aspects of TTTS, offering guidance on patient/family support and coping strategies. It includes the latest guidelines and evidence-based practices for TTTS, helping clinicians stay current with advancements in the field and ensuring they adhere to the best standards of care.In addition, the book offers real-world case studies and practical guidance to enable clinicians to effectively apply their knowledge in clinical settings, enhancing their ability to diagnose and manage TTTS cases. Written by various experts in the field, this multidisciplinary perspective fosters collaboration and enables anyone involved in this field to make informed decisions in complex TTTS cases.

  • Wilson and Mulcahy’s Prosthetic Urology

    A Comprehensive Guide to Surgery for Erectile Dysfunction and Male Incontinence
    • 1st Edition
    • Jay Simhan + 1 more
    • English
    Wilson and Mulcahy’s Prosthetic Urology: A Comprehensive Guide to Surgery for Erectile Dysfunction and Male Incontinence is a comprehensive reference that covers the surgical management of erectile dysfunction and male incontinence.This book's chapters cover a wide range of topics, including the history of penile prostheses, practice considerations, patient selection, placement techniques for malleable and inflatable penile prostheses, management of complications, and infection prevention and management. Additionally, specialized topics such as managing Peyronie's disease, priapism, and penile prosthesis placement in transgender patients are also addressed.Written by esteemed experts in the field, this reference offers valuable insights and guidance for healthcare professionals. Whether you are a practicing prosthetic urologist, a trainee looking to enhance your skills, or a device manufacturer aiming to improve surgical quality, this essential reference will elevate your knowledge and expertise.Tibor Imley's cover photo features Dr. Wilson and Dr. Mulcahy, after whom this title is named. This book honors their pioneering contributions to prosthetic urology.

  • A Comprehensive and Practical Guide in Clinical Trials

    • 2nd Edition
    • Brenda Wright
    • English
    The Comprehensive and Practical Guide in Clinical Trials, Second Edition offers a thorough update to the foundational handbook on clinical trial conduct. It reflects the evolving landscape of clinical research since 2017, incorporating new regulatory guidelines, innovations in device trials, and the shift to electronic data capture and management. This resource addresses the needs of clinical trial staff by detailing processes essential to successful trial execution. Covering all aspects of clinical research, the book includes chapters on trial phases, site selection, regulatory requirements, contracts, protocol development, informed consent, and data management. New chapters focus on project management, electronic source documents, and pharmacy operations. Each chapter integrates practical tools such as checklists, templates, and case studies to facilitate understanding and application. This handbook uniquely supports the entire clinical trial team—including investigators, coordinators, pharmacists, data managers, and regulatory personnel—by clarifying roles and responsibilities and illustrating how their tasks interconnect. Its accessible style and comprehensive scope make it an indispensable guide for planning, conducting, and closing clinical trials effectively and in compliance with international standards.

  • Capsule Endoscopy in Pediatric Patients from Theory to Practice

    • 1st Edition
    • Thomas M. Attard
    • English
    Capsule Endoscopy in Pediatric Patients from Theory to Practice is a practical and authoritative guide that empowers pediatric gastroenterologists, physicians, and trainees to navigate the complexities of Video Capsule Endoscopy (VCE) in children. With a focus on bridging knowledge gaps and providing practical insights, this book offers updated information on understanding and utilizing VCE in the pediatric population. The book covers the background and technical aspects of VCE, including guidance on setting up a pediatric VCE service and an overview of indications and limitations. It delves into practical aspects such as preprocedural preparation, artifact reduction techniques, and management of capsule retention. By exploring VCE in various disease conditions such as inflammatory bowel disease, gastrointestinal bleeding, hereditary polyposis syndromes, and chronic abdominal pain, readers gain a comprehensive understanding of diagnosis, surveillance, and management. Special content elements, including key terms, case studies, and a timeline of recent advances, enhance the learning experience. This essential resource empowers readers to optimize patient care, make informed decisions, and confidently navigate the realm of VCE in children.

  • SARS-CoV-2 Infection and the Development of Therapeutics

    • 1st Edition
    • Amit Kumar Nayak + 1 more
    • English
    SARS-CoV-2 Infection and the Development of Therapeutics provides thorough insights into the SARS-CoV-2 virus, viral infection and transmission, the emergence of variants, need for testing and rapid diagnosis, and the development of effective therapeutic interventions. This book begins with an introduction that highlights the urgent need for effective therapies against this virus. The second section dives into the pathophysiology of viral infections, providing valuable insights into transmission dynamics and the essential role of testing and rapid detection methods. The third section examines antiviral agents and treatments, addressing the numerous challenges in drug design, the immune response, and vaccine development.Finally, the fourth section tackles related issues such as co-infections in COVID-19 patients, the landscape of clinical trials, regulatory considerations, and future perspectives on antiviral therapies. With contributions from an international group of experts, this book offers a well-rounded understanding of the ongoing battle against SARS-CoV-2 and the COVID-19 disease it causes.

  • Biopolymer-Based Therapeutics for Inflammation Modulation in Wound Care

    • 1st Edition
    • Neha Raina + 2 more
    • English
    Biopolymer-Based Therapeutics for Inflammation Modulation in Wound Care presents a comprehensive, biomarker-driven exploration of how natural and engineered biopolymers are transforming the management of acute, chronic, and non-healing wounds. Positioned at the intersection of biomaterials science, pharmaceutical innovation, and clinical practice, the book addresses one of the central challenges in wound care: persistent inflammation that delays tissue repair and regeneration. Beginning with the biological and clinical foundations of wound healing, the book systematically examines inflammatory pathways and key biomarkers such as TNF-α, IL-6, ROS, and VEGF.It then advances into in-depth coverage of natural biopolymers—includin... collagen, chitosan, hyaluronic acid, silk-derived polymers, and marine polysaccharides—and their roles in immune modulation, macrophage polarization, and redox balance. Dedicated sections explore advanced delivery platforms such as nanofibers, smart hydrogels, nanozymes, and stimuli-responsive dressings, alongside emerging precision technologies including 3D printing and AI-guided material design. With a strong translational focus, the book bridges laboratory research and real-world application, addressing regulatory pathways, manufacturing scalability, and commercialization challenges.

  • Spaceflight Ophthalmology and Medicine

    A Comprehensive Guide to Ocular Health and Related Systemic Health Risks in Astronauts and Space Travelers
    • 1st Edition
    • Ryung Lee + 4 more
    • English
    Spaceflight Ophthalmology and Medicine: A Comprehensive Guide to Ocular Health and Related Systemic Health Risks in Astronauts and Space Travelers provides a comprehensive exploration of ocular health issues faced by astronauts during space missions. The book brings together contributions from leading experts in various fields, addressing the multifaceted risk factors associated with spaceflight and their implications for vision and overall health. Sections examine risk factors for ophthalmic diseases, including the effects of microgravity, space radiation, and oxidative stress, and explore innovative approaches in spaceflight ophthalmology, such as advanced diagnostic techniques and potential treatments for ocular conditions specific to the space environment. This book serves as an essential resource for researchers, clinicians, and space medicine professionals. By offering insights into the latest research and practical applications, it enhances understanding of ocular health in space and promotes the development of effective strategies to ensure astronaut safety and mission success.

  • Introduction to Structural Bioinformatics

    • 1st Edition
    • Yang Zhang + 3 more
    • English
    Introduction to Structural Bioinformatics offers a complete overview on the fundamental concepts and methodologies of structural bioinformatics and computational structural biology. The book is divided into three sections, beginning with a discussion of the key principles of bioinformatics and fundamental aspects, including bioinformatics databases, multiple sequence alignment, and machine learning. Section two then moves on to structural bioinformatics, where topics include Monte Carlo simulation, protein structure prediction, RNA structure prediction, and protein design. The final section of the book focuses on experimental structural determination, where chapters focus on techniques including X-ray crystallography, nuclear magnetic resonance and cryo-electron microscopy. This is an ideal guide on key principles, methods, and the most up-to-date developments across structural bioinformatics and computational structural biology. It will be a comprehensive reference for postgraduate students, instructors, and researchers working in these and adjacent subjects.

  • Sarcoma Immunology and Immunotherapy

    From Cellular Mechanisms to Clinical Translation
    • 1st Edition
    • Joseph Crompton
    • English
    Sarcoma Immunology and Immunotherapy offers a timely and comprehensive review of the rapidly evolving field of sarcoma immunology and immunotherapy. This book serves as an essential resource for healthcare professionals, scientists, and patients, providing insights into the immunologic features of sarcoma and the latest immune-based treatments. Focussing on the recent advances, the book discusses the sarcoma microenvironment and the development of innovative immunotherapies tailored for sarcoma patients. Readers will benefit from a thorough overview of existing knowledge, encompassing foundational concepts in sarcoma immunology, a detailed examination of laboratory research, and a complete summary of ongoing immunotherapy trials. This holistic approach ensures a robust understanding of the current landscape in sarcoma research and treatment. By equipping readers with essential background information and comprehensive reviews, this book fosters a deeper understanding of sarcoma immunology and therapeutic strategies. It empowers healthcare professionals and scientists to stay abreast of critical studies, ultimately enhancing patient care and outcomes in this challenging field.

  • RNA-Binding Proteins Part D

    • 1st Edition
    • Volume 746
    • English
    A central theme of this volume is the dynamic relationship between RNA structure, RNA-binding proteins, and cellular organization. The chapters integrate experimental, computational, biochemical, biophysical, imaging, and systems-level approaches to investigate how RNA–protein interactions regulate RNA processing, translation, localization, stability, phase separation, and cellular stress responses. As Volume 746 of the Methods in Enzymology series, the volume emphasizes the integration of methodological innovation with biological applications, providing researchers with practical approaches to dissect how RNA–protein interactions govern RNA fate and function, biomolecular condensate formation, and stress granule assembly.Overall, this collection highlights the transition of RNA biology from a primarily sequence-centered discipline toward a more dynamic view in which RNA structure, molecular interactions, phase separation, cellular organization, and signaling are intimately connected. It will therefore be a valuable resource for researchers and students seeking both practical methodologies and mechanistic insights into the rapidly expanding field of RNA biology.

  • Neonatal Surgery

    Techniques, Evidence and Outcomes
    • 1st Edition
    • David J. Hackam
    • English
    Neonatal Surgery: Techniques, Evidence, and Outcomes addresses the growing need for specialized surgical care in neonates, whose unique physiology demands distinct considerations from other surgical populations. Written by leaders in the field, this definitive textbook is the first devoted entirely to neonatal surgery, filling a vital gap in the literature with evidence-based guidance on timing, technique, and postoperative management for optimal outcomes. The book opens with the general care of the neonatal surgical patient, covering anatomy and physiology, preoperative workup, anesthesia, pain management, nursing, family experience, transport, nutrition, pharmacy, vascular access, and radiographic considerations. Subsequent sections address specialized areas including head and neck, thoracic, abdominal, urologic, orthopedic, neurosurgical, plastic and reconstructive, and congenital heart surgery, each offering detailed, evidence-based guidelines and techniques for managing specific conditions. The book concludes with a look at the future of neonatal surgery and considerations for surgery in low- and middle-income countries. An invaluable resource for clinical learners and practicing surgeons alike, it serves as a critical how-to guide for students and residents and an authoritative reference for practicing surgeons, including evidence-based management strategies. Researchers will find it indispensable for understanding the metabolic and physiological responses to neonatal surgery, adding translational relevance to their work. This textbook is essential for anyone involved in the surgical care of neonates, providing the knowledge needed to achieve the best possible outcomes

  • Sleep Neurology

    • 1st Edition
    • Anne Marie Morse
    • English
    Sleep Neurology explores the intricate relationship between sleep and neurological health, bridging the gap between theoretical knowledge and practical application. This comprehensive reference highlights the role of sleep in overall health and provides an examination of how sleep influences a wide range of neurological disorders. From neurodevelopmental issues to neurodegenerative diseases, this book offers a detailed review of how sleep science can be applied to improve patient outcomes in various neurological conditions. Structured around key neurological topics, the book offers insights into conditions such as epilepsy, stroke, and traumatic brain injury, emphasizing the importance of sleep management in their treatment. Each chapter not only discusses the scientific underpinnings of sleep but also provides tangible strategies for integrating sleep health into primary neurological care.

  • Wearable Biosensors for Healthcare

    Techniques and Applications
    • 1st Edition
    • Vigneswaran Narayanamurthy + 2 more
    • English
    Wearable Biosensors for Healthcare: Techniques and Applications is a comprehensive exploration of the transformative role of wearable biosensors in modern healthcare. The book explains the integration of artificial intelligence in health monitoring, showcasing how AI enhances data analysis and personalized health insights. Through practical case studies, sections illustrate real-world implementations across various healthcare domains, including chronic disease management, fitness tracking, and mental health monitoring. Additionally, it emphasizes the importance of interdisciplinary design principles, highlighting the need for collaboration among engineering, medicine, and data science to develop effective wearable solutions. Addressing technical challenges and proposing future research directions, this book serves as a vital resource for anyone interested in the intersection of technology and healthcare, ultimately aiming to inspire further innovation in the field of wearable biosensing.

  • Legal Issues in Quality for Healthcare Institutions

    • 1st Edition
    • Ramesh Sachdeva
    • English
    Legal Issues in Quality for Healthcare Institutions provides the perspective of practicing physicians, lawyers, and academic legal scholars to comprehensively address the implications for quality of care and patient safety both from a legal, medical, and improvement science standpoint. Hospital administrators, physicians, nurses, researchers, legal scholars, as well as regulatory and compliance officers working in hospitals and acute care facilities will find this to be a helpful resource in understanding and addressing the many facets and issues in the field of medicine and law related to quality and patient safety.

  • Drug Repurposing in Cancer Research

    • 1st Edition
    • Ranjita Shegokar + 1 more
    • English
    Drug Repurposing in Cancer Research investigates the innovative use of drug repurposing in oncology, focusing on emerging and re-emerging cancer types. The book provides a comprehensive yet concise overview of current trends, making it an essential resource for academics and professionals in the field. Structured into 21 chapters, the book presents foundational facts alongside practical and clinically relevant data. It covers topics ranging from market dynamics to AI-driven transformations in cancer treatment, highlighting the rapid advancements in oncology. This compilation ensures that readers are equipped with the latest information necessary for effective research and development. For pharmaceutical researchers, biomedical scientists, and clinicians, "Drug Repurposing in Cancer Research" offers valuable insights into the growing demand for innovative cancer treatments. It serves as a timely resource for understanding the potential of repurposed drugs, supporting efforts in cancer prevention and treatment strategies.

  • Urinary Incontinence

    Integrating Science and Clinical Practice
    • 1st Edition
    • Marcus Drake + 2 more
    • English
    Urinary Incontinence: Integrating Science and Clinical Practice succinctly describes the importance of lower urinary tract physiology to all for an understanding of urinary incontinence and its clinical treatment. World-leading contributors describe the key influences on mechanisms and therapies for proper understanding of the scientific basis of incontinence.The first part of the book is dedicated to System Physiology: Function and Adaptation. In this section, an anatomical sequence is followed for presenting the chapters, moving from the lower urinary tract organs upwards through the spinal centers to the brain. These chapters discuss what is known and unknown for crucial areas, such as neurological control and co-ordination, bladder fibrosis, bladder physiology and more.The second part is dedicated to Incontinence: Mechanism and Therapy. In this clinical application section, chapters derive from the clinical classification of incontinence and explore topics such as the role of urodynamics; mechanisms underpinning medical and interventional treatments; the sensations arising from the lower urinary tract; adverse effects of therapy and the considerable faced in managing incontinence.Written for researchers and clinicians, this book is a welcomed resource for those aiming to understand more about urinary incontinence.

  • Roles of the Cerebellum in Motor Control

    Foundations, Experimental Approaches and Clinical Applications
    • 1st Edition
    • Mario Manto + 2 more
    • English
    Roles of the Cerebellum in Motor Control: Foundations, Experimental Approaches and Clinical Applications is a groundbreaking, comprehensive reference on the intricate relationship between the cerebellum and motor function. Spanning five thorough sections, this book examines experimental approaches, from single neurons to networks, unraveling the mysteries of olivocerebellar somatotopy, motor prediction, and the cellular basis of motor learning. With chapters dedicated to neuroimaging, physiology, and pathophysiology, users will gain insight into the cerebellum's role in conditions such as tremor, dystonia, and Parkinson’s disease.From wearable sensors to digital gait biomarkers, various chapters offer a cutting-edge look at sensor technology and its application in assessing cerebellar function and rehabilitation. The book concludes with a discussion on research and clinical implications, providing a roadmap for translating laboratory findings into effective therapeutic strategies, making it an indispensable resource for researchers, clinicians, and students alike.

  • Next-Generation Food Bioactives

    Mechanisms, Technologies, and Translational Applications
    • 1st Edition
    • Karuppusamy Arunachalam + 3 more
    • English
    Next-Generation Food Bioactives: Mechanisms, Technologies, and Translational Applications offers a thorough examination of food-derived bioactive compounds such as polyphenols, flavonoids, polysaccharides, peptides, and saponins, and their significance in health promotion, disease prevention and the development of functional foods and nutraceutical products. Divided into six comprehensive sections, the book covers the fundamental properties of these compounds, advanced extraction and analysis methods, and explores their molecular mechanisms and interactions with the gut microbiome. Next-Generation Food Bioactives: Mechanisms, Technologies, and Translational Applications further discusses challenges related to bioavailability, safety, and regulatory considerations, while highlighting emerging trends such as the integration of artificial intelligence and omics technologies in bioactive discovery and functional food formulation. Designed for researchers, industry scientists, and healthcare professionals, this book provides valuable insights to support innovation and evidence-based development in the field of food bioactives.

  • Mechanobiology and Mechanomedicine

    From Fundamentals to Applications
    • 1st Edition
    • Lifang Hu + 2 more
    • English
    Mechanobiology and Mechanomedicine: From Fundamentals to Applications offers an in-depth investigation of the role mechanical stimuli plays in biological systems, from cellular behavior to disease development. Organized into three parts, the book initially covers the fundamentals of mechanobiology, exploring cellular and molecular mechanobiology including mechanical force types, mechanosensors and transducers, mechanosensitive signaling pathways and nuclear mechanotransduction. In addition, the application of finite element modeling techniques in studying multiscale mechanobiology of bone are included. The second section focuses on mechanobiology more broadly in health and disease, spanning its role across bone, cartilage, the dental and periodontal tissues, muscle, the cornea and sclera, and in airways. Each chapter considers the molecular and cellular mechanisms of mechanotransduction in these areas, as well as its significance for associated physiological and pathological conditions. The final section examines novel technologies like high-resolution mechanical imaging, organoids and artificial intelligence, concluding with the translational potential of mechanomedicine and its therapeutic applications.Mechano... and Mechanomedicine: From Fundamentals to Applications serves as a comprehensive and systematic overview of mechanobiology, sharing insights into the latest research advances and clinical relevance. Taking an interdisciplinary approach, this book is ideal for scientists, researchers and advanced students working across a range of areas including molecular biology, cell biology, translational medicine, biomechanics, biomedical engineering, biotechnology and related fields.

  • Theranostics for Cancer Targeting

    • 1st Edition
    • Ranjita Shegokar + 1 more
    • English
    This groundbreaking Theranostic book delivers the definitive roadmap for the next generation of precision oncology by systematically detailing the clinical, regulatory, and drug delivery landscapes of theranostics—the revolutionary integration of therapy and diagnostics—across 20-22 major cancer types. Designed for medical publishers, clinicians, and biotech researchers, this chapter is a structural framework for each malignancy, bridging laboratory breakthroughs in nanotechnology, green nanochemistry, drug delivery, diagnostics, and AI with real-world clinical applications. It serves as an essential commercial and academic asset, offering unprecedented depth on FDA/EMA regulatory hurdles, technology transfer pathways, and actionable data tables that track active clinical trials and global research groups. By addressing key market trends and regulatory challenges, it serves as an essential, multidisciplinary resource for driving personalized oncology and improving patient outcomes

  • Artificial Intelligence in Agricultural Systems

    Fundamentals and Advances
    • 1st Edition
    • Mohammad Mehdizadeh
    • English
    Artificial Intelligence in Agricultural Systems: Fundamentals and Advances focuses on advancements in AI in and draws upon the multi-faceted challenges of modern agriculture. This book curates the latest strands of AI applications that are reshaping agricultural systems, including current trends and emerging technologies. It offers an overview of the evolving agricultural landscape and foregrounds the critical role of AI in driving innovation and enhancing productivity in this essential sector. Organized into four parts, it introduces agricultural systems and AI fundamentals, including machine learning, deep learning, natural language processing, and robotics. It then pivots to data collection and processing techniques, explicating the use of sensors, IoT devices, remote sensing, and UAVs. Core applications in crop and livestock management receive emphasis, covering yield prediction, pest detection, precision irrigation, and sustainable farming practices. The final sections address the limitations of AI in agriculture, future trends, and policy recommendations, providing an overarching understanding of AI's responsible adoption. Artificial Intelligence in Agricultural Systems is an important resource for upper-level undergraduate and graduate students studying the impact of AI technologies on agriculture and food production. Researchers, practitioners, and policymakers studying the intersections of agriculture, environmental science, data science, and engineering will find this book compelling as well.

  • Quercetin in Drug Discovery

    • 1st Edition
    • Gautam Sethi + 2 more
    • English
    Quercetin in Drug Discovery is a detailed reference exploring the multifaceted pharmacological potential of quercetin, a naturally occurring flavonoid with significant therapeutic promise. Addressing the critical need for consolidated knowledge, this guide highlights quercetin’s diverse biological activities and the translational challenges limiting its clinical applications, making it essential for researchers and pharmaceutical scientists. The comprehensive table of contents covers quercetin’s pharmacological properties, molecular docking studies, and ADME profiles, alongside therapeutic applications in cardiovascular diseases, cancer, and other conditions. It further examines bioavailability enhancement strategies, drug formulation, innovative delivery systems, and clinical trial evidence. Contributions from leading experts provide detailed insights into signaling pathways, molecular targets, and synthetic derivatives. Quercetin in Drug Discovery equips pharmacologists, medicinal chemists, and pharmaceutical scientists with critical information to advance research and drug development. By addressing bioavailability issues and regulatory considerations, this reference supports the translation of quercetin from bench to bedside, fostering innovation in natural product-based therapeutics.

  • Biomaterials in Cancer Therapy

    Innovations and Applications
    • 1st Edition
    • Alok Raghav
    • English
    Biomaterials in Cancer Therapy: Innovations and Applications explores the critical role of functional biomaterials in addressing one of today’s most pressing health challenges—cancer. Despite advancements in therapies, cancer continues to claim millions of lives annually, necessitating innovative approaches that integrate engineering and pharmaceutical sciences. This book highlights the potential of engineered biomaterials to enhance drug delivery, minimize side effects, and promote tissue regeneration, ultimately improving patient outcomes. The content examines cutting-edge innovations in functional biomaterials, including their applications in targeted drug delivery and immunotherapy, while emphasizing the role of nanotechnology in developing effective cancer theranostics with minimal toxicity. Targeted at academicians, physicians, and industry professionals, this book serves as a vital resource for understanding the transformative potential of functional biomaterials in oncology. By addressing real-world challenges and incorporating diverse perspectives, it inspires innovative solutions that enhance global healthcare outcomes for cancer patients.

  • Management of Chronic Kidney Disease and Its Complications

    • 1st Edition
    • Thakur Gurjeet Singh + 4 more
    • English
    Management of Chronic Kidney Disease and Its Complications  presents the latest scientific advances in diagnosing and managing Chronic Kidney Disease (CKD) and its diverse complications. This authoritative text covers molecular mechanisms such as inflammation and oxidative stress, genetic and epigenetic factors, and explores cutting-edge technologies including artificial intelligence and regenerative medicine. With detailed chapters on cardiovascular, metabolic, neurological, and hematological complications, the book offers a holistic approach to understanding CKD’s complexity and evolving treatment strategies.The book’s content is organized to provide a thorough exploration of CKD, beginning with foundational topics like genetic contributions and diagnostic evaluation, progressing through specific complications such as diabetic nephropathy, hypertension, and urologic conditions. Special focus is given to management strategies, nutritional interventions, and unique considerations in pediatric, geriatric, and pregnant populations. Emerging therapies, including precision medicine, gut microbiota modulation, and AI-driven early detection, are also extensively covered to keep readers at the forefront of nephrology research and clinical practice.Management of Chronic Kidney Disease and Its Complications is an essential resource for nephrologists, general practitioners, medical students, nursing professionals, and healthcare providers involved in kidney disease care and research.

  • The Human Nervous System

    • 4th Edition
    • George Paxinos + 2 more
    • English
    The 4th Edition of the classic book The Human Nervous System continues to assemble contributions from world leaders in research on the brain, spinal cord and peripheral nervous system. This book has been edited by the best-known team of brain cartographers, and it has been completely revised to present the cutting edge of human neuroscience. The structure, connections and function are explained in depth, making this book essential to any student or scientist interested in brain anatomy and function.

  • CRISPR Therapeutics Delivery Strategies

    • 1st Edition
    • Prashant Kesharwani
    • English
    CRISPR Therapeutics Delivery Strategies is a structured and comprehensive resource in the rapidly evolving field of CRISPR technology. As CRISPR-Cas systems translate to therapeutics, this reference provides critical insights into the challenges and advancements in effective delivery mechanisms. The book captures the essence of CRISPR's transformative potential in gene therapy, targeted cancer treatments, and personalized medicine, while also highlighting the importance of innovative delivery strategies to overcome existing barriers. The contents of the book offers a systematic exploration of CRISPR technology, beginning with foundational concepts and progressing to targeted drug delivery strategies. Each chapter explore specific applications, including CRISPR in cancer therapy, gene editing for rare diseases, and overcoming delivery barriers such as the blood-brain barrier. Additionally, ethical and regulatory considerations are addressed, providing a holistic view of the current landscape and future directions in CRISPR research. CRISPR Therapeutics Delivery Strategies serves as an essential resource for students, researchers, and professionals in the fields of pharmacology, biotechnology, and gene therapy. By compiling cutting-edge research and expert perspectives, this reference helps pharmaceutical scientists to navigate the complexities of CRISPR technology and its applications.

  • Protein Misfolding

    • 1st Edition
    • Timir Tripathi
    • English
    Protein Misfolding explores the structural and biochemical foundations of protein misfolding, highlighting its wide-reaching implications for cellular function, disease progression, and biomedical innovation. This book provides a comprehensive understanding of how proteins deviate from their native conformations and the resulting biological consequences. Focusing on both physiological and pathological misfolding, the volume covers essential topics such as folding quality control, molecular chaperones, degradation pathways, and proteostasis. It presents in-depth analyses of protein aggregation mechanisms, amyloid formation, and misfolding-associate... diseases including Alzheimer's, Parkinson's, and prion-related disorders. Additional chapters explore structural approaches to understanding misfolded states, computational modeling of aggregation kinetics, and current efforts to design therapeutics that restore folding homeostasis or prevent toxic accumulation. The book also addresses the cellular response to misfolding stress and the integration of folding dynamics with cellular signaling pathways.This book is a valuable resource for researchers, educators, and professionals in biochemistry, structural biology, molecular medicine, biotechnology, and related disciplines. It supports efforts to understand the fundamental principles of protein structure and function, while offering insight into emerging therapeutic strategies and future research directions in disease-focused protein science.

  • RNA-binding Proteins Part C

    • 1st Edition
    • Volume 745
    • English
    This volume of Methods in Enzymology presents a practical and multidisciplinary collection of contemporary methods for investigating RNA biology, RNA-binding proteins (RBPs), RNA–protein interactions, ribonucleoprotein (RNP) complexes, biomolecular condensates, liquid–liquid phase separation, RNA processing, translation, and RNA-mediated regulation. The chapters integrate complementary experimental and computational approaches, including biochemical reconstitution, quantitative microscopy, transcriptomics, proteomics, interactomics, NMR spectroscopy, structural biology, computational analysis, and tissue-based techniques.Together, these methods provide a versatile framework for elucidating how RNA and RBPs regulate cellular organization, gene expression, RNA metabolism, RNA processing, translation, and biomolecular phase behavior. Particular emphasis is placed on emerging applications in disease-associated molecular pathways, including neurodegeneration and neurological disorders, with coverage of topics relevant to Alzheimer’s disease, Tau biology, and HIV-associated neurocognitive disorders. This volume provides researchers with practical methodological strategies for dissecting RNA–protein interactions and defining RBP function across molecular, cellular, and disease contexts. The collection is designed to serve as a valuable methodological resource for researchers investigating the mechanisms by which RNA–protein networks govern cellular processes and contribute to human disease.

  • Advances in Nanocarriers for Biofilm-Associated Infections

    From Research to Clinical Practice
    • 1st Edition
    • Neeraj Mishra + 2 more
    • English
    Advances in Nanocarriers for Biofilm-Associated Infections: From Research to Clinical Practice addresses the critical challenge of treating biofilm-associated infections, which are resistant to conventional antibiotics due to their protective microbial communities. This reference compiles cutting-edge research on nanocarriers, including nanoparticles, liposomes, dendrimers, and polymeric micelles, emphasizing their design and application to penetrate biofilms and enhance antimicrobial delivery. The comprehensive content covers biofilm formation, resistance mechanisms, and multidrug resistance, followed by detailed chapters on nanocarrier synthesis, functionalization, and therapeutic efficacy. Clinical and translational aspects are examined through case studies on chronic wounds, medical device infections, and respiratory biofilms, alongside regulatory hurdles and future research directions. The book features contributions from international experts, providing a multidisciplinary perspective on nanotechnology’s role in infection control.It equips researchers, clinicians, and pharmaceutical professionals to understand complex biofilm biology, apply novel drug delivery systems, and navigate clinical challenges, ultimately supporting the development of improved treatments for persistent biofilm-related infections.

  • Network Pharmacology

    Exploring New Horizons in Drug Discovery
    • 1st Edition
    • Veeranoot Nissapatorn + 4 more
    • English
    Network Pharmacology: Exploring New Horizons in Drug Discovery explores the innovative network pharmacology approach—which examines the intricate interactions between disease targets and metabolites—offering a systems-based perspective that is essential for modern drug discovery. Readers will find in-depth discussions on metabolite databases, computational tools, and the role of natural products in drug discovery. Notable topics include network-based approaches to drug repurposing, personalized medicine, and the implications of traditional medicine in pharmacological research, all supported by real-world case studies and advanced computational methodologies.By integrating multiomics data, including metabolite profiling, the book addresses the limitations of conventional methods and opens new pathways for understanding disease mechanisms and therapeutic responses. This is a foundational guide for researchers, pharmaceutical scientists, and academic scholars across diverse fields such as pharmacology, metabolomics, and systems biology.

  • Central Nervous System Viral Infections

    • 1st Edition
    • Karen L. Roos + 1 more
    • English
    Central nervous system viral infections pose one of the greatest threats to humanity, as evidenced by recent history with SARS-CoV-2 (COVID 19), HIV, and others. Understanding their effects, therapeutics, and prevention are a top priority for all. "Central Nervous System Viral Infections" reviews the mechanisms of viral infections, current viruses of interest, diagnosis, course, and therapeutics, as well as prevention. Post infection syndromes and complications are also reviewed. Coverage includes Covid, HIV, Zika, EBOLA, Marburg, Herpes, Measles, Mumps, Polio, and more.

  • Disorders of Memory

    • 1st Edition
    • Andrew E. Budson + 1 more
    • English
    Disorders of Memory provides a new update on research pertaining to memory disorders, with a central focus on differing components of memory processes, as well as clinical conditions affecting memory. The book covers methods of assessment and clinical treatment, management, and rehabilitation of these disorders. With chapters written by leading international experts, it provides an overview of our current knowledge on memory disorders that will be of benefit to both researchers and practitioners interested in neurology.

  • Advances in Mitochondrial Drug Delivery

    From Molecular Mechanisms to Clinical Translation
    • 1st Edition
    • Prashant Kesharwani
    • English
    Advances in Mitochondrial Drug Delivery: From Molecular Mechanisms to Clinical Translation addresses the critical need for a comprehensive resource on mitochondrial-target... drug delivery systems. As recent advancements in drug delivery systems (DDS) have shown substantial promise in treating diseases linked to mitochondrial dysfunction, there is a pressing demand for a consolidated reference that covers both the foundational aspects and the latest innovations in this field. The book's Table of Contents encompasses a wide range of topics, beginning with the fundamentals of mitochondrial biology and drug delivery, followed by various mitochondrial-target... drug delivery strategies. It further explores advanced applications of these systems in treating cancer, neurodegenerative diseases, cardiovascular conditions, and more. Additionally, the book discusses future directions, clinical translation, and regulatory challenges, ensuring a holistic view of the subject matter. Advances in Mitochondrial Drug Delivery offers significant benefits to researchers, students, and professionals in pharmaceutical sciences and nanotechnology. By integrating diverse perspectives from leading experts, the book serves as an essential resource for understanding the complexities of mitochondrial-target... therapies, thereby fostering advancements in drug delivery systems and therapeutic strategies.

  • Insect Bioactives

    Innovations in Food, Feed, Pharma and Cosmetics
    • 1st Edition
    • Abdalbasit Adam Mariod + 2 more
    • English
    Insect Bioactives: Innovations in Food, Feed, Pharma and Cosmetics serves as a comprehensive resource for researchers and professionals seeking to harness the power of insects as sustainable bioactive sources and beneficial health and wellness solutions. The book identifies the nutritional and chemical composition of insects, presenting them as versatile ingredients for the development of functional foods, nutraceuticals, animal feed and cosmetics. By examining how edible insects can be reared on agri-food by-products and organic waste, this volume illustrates how feeding strategies can influence their nutritional and bioactive profiles. The text also addresses potential allergenic risks and consumer behavior insights, equipping readers with strategies to promote acceptance of insect-based products in the market.Structured into eight sections, Insect Bioactives: Innovations in Food, Feed, Pharma and Cosmetics covers a wide array of topics essential for understanding insect bioactives. From the foundational overview of insect-based compounds to their applications in functional foods, animal feed, pharmaceuticals, and cosmetics, each section provides insights into the health benefits and technological innovations associated with insect bioactives. The text also discusses regulatory considerations and features case studies that showcase successful applications in various industries.

  • Decoding the JAK-STAT Pathway

    Emerging Insights and Clinical Applications Across Diseases
    • 1st Edition
    • Meenakshi Dhanawat + 1 more
    • English
    Decoding the JAK-STAT Pathway: Emerging Insights and Clinical Applications Across Diseases offers a comprehensive exploration of one of the most vital molecular signaling pathways in human health and immune regulation. This reference addresses the critical need for an integrated resource that connects fundamental immunological mechanisms with translational and clinical applications, particularly in autoimmune, inflammatory, and infectious diseases. The book covers the pathway’s physiological roles in cytokine signaling, immune homeostasis, and cellular communication, as well as its dysregulation in conditions such as rheumatoid arthritis, inflammatory bowel disease, neuroinflammation, and viral infections. Its chapters feature contributions from global experts, detailing recent advances in targeted therapies, including JAK inhibitors, and their potential for personalized medicine. The content is organized to highlight disease-specific roles, therapeutic strategies, and emerging research directions, making it an essential resource for immunologists, biomedical scientists, clinicians, and pharmaceutical researchers seeking an authoritative, up-to-date guide to the molecular and clinical aspects of JAK-STAT signaling. By elucidating how this pathway influences immune responses and disease progression, the book facilitates a deeper understanding of immune regulation and offers insights into novel treatment approaches, ultimately supporting advancements in immunotherapy and precision medicine across diverse patient populations worldwide.

  • Neuroinflammation and Biomarker Discovery

    From Mechanisms to Clinical Application
    • 1st Edition
    • Arun Kumar Singh + 1 more
    • English
    Neuroinflammation and Biomarker Discovery: From Mechanisms to Clinical Application offers a detailed exploration of the molecular and cellular processes underlying neuroinflammatory conditions. This essential reference addresses the urgent need for advanced biomarkers that can facilitate early diagnosis, monitor disease progression, and guide personalized treatments in neurodegenerative and autoimmune disorders such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis. The book synthesizes current knowledge on neuroimmune interactions, glial cell activation, blood-brain barrier integrity, and innate immune signaling pathways, providing a comprehensive framework for understanding neuroinflammatory mechanisms. It also covers state-of-the-art platforms for biomarker discovery, including transcriptomics, proteomics, lipidomics, epigenomics, extracellular vesicles, and neuroimaging techniques, emphasizing their translational potential. The inclusion of disease-specific biomarker landscapes enhances its relevance for clinicians and researchers working in diagnostics and drug development. The final sections focus on translational applications, such as clinical trial design, biomarker validation, and the integration of AI-driven multi-omics data for personalized neuroimmunology. This volume is an indispensable resource for neuroscientists, clinicians, graduate students, biotech professionals, and data scientists seeking to advance understanding and innovation in neuroinflammatory research and clinical practice. By bridging basic science and clinical application, it aims to accelerate the development of targeted therapies and diagnostic tools, ultimately improving patient outcomes in neuroinflammatory diseases

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