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Elsevier

Books in Life sciences

  • Gender Affirming Hormone Therapy in Humans

    Evidence from Murine Models
    • 1st Edition
    • Jeffrey David Zajac
    • English
    Gender Affirming Hormone Therapy in Humans: Evidence from Murine Models is an unprecedented reference for scientists, researchers, students and anyone interested in this field of research. The book is a review of the current state of mouse animal models of relevance to transgender health. It's divided into chapters specific for different tissues in which mouse models are described and their relevance to human health is discussed. This is a novel reference summarizing what these models demonstrate about the benefits and risks of GAHT and the most effective and lowest risk approach to treatment. The models suggest applications of this research to human studies and treatment of transgender people. There is an expanding number of transgender people with are few evidence based books that address this field relating to the importance and growing role of murine models.

  • Decision Neuroscience

    • 2nd Edition
    • Jean-Claude Dreher
    • English
    Decision Neuroscience: An Integrative Perspective presents the most recent and compelling lesional, neuroimaging, electrophysiological... and computational studies, in combination with hormonal and genetic studies, which have led to a clearer understanding of the neural mechanisms behind reward and decision making. The neural bases of reward and decision-making processes are of critical interest to scientists because of the fundamental role that reward plays in a number of behavioral processes (such as motivation learning, and cognition), and because the neural bases have theoretical and clinical implications for understanding dysfunctions of the dopaminergic system in several neurological and psychiatric disorders. This book will constitute a comprehensive update of ground-breaking work addressing fundamental questions about the nature of behavior: how does the brain process reward and how does it make decisions when facing multiple options? And will feature entirely new content, as well as expanded coverage on drug and behavioral addiction, the role of subthalamus stimulation in neurological disorders and neuroeconomics.

  • Molecular Pathology

    The Molecular Basis of Human Disease
    • 3rd Edition
    • Gregory J. Tsongalis + 1 more
    • English
    Molecular Pathology: The Molecular Basis of Human Disease, Third Edition is a comprehensive reference that explores the molecular mechanisms and basis of major human diseases. Expertly crafted, this book is designed for use as a teaching tool for medical students, biomedical graduate students, and allied health students. It serves as an advanced resource for pathology residents, postdoctoral fellows, basic scientists, and physician scientists engaged in disease-related research, presenting traditional pathology in the context of translational molecular medicine. In this new edition, the chapters have been fully updated and rearranged for better logical flow.Notably, four new chapters have been included, covering topics such as the pathogenesis of fibrotic diseases, mechanisms of mutation, molecular basis of soft tissue disease and pathology, and pathogenesis and pathophysiology. The book remains an invaluable reference for anyone seeking a deeper understanding of the molecular aspects of human disease.

  • Structural and Functional Dynamics of Nontuberculous Mycobacterium Proteins

    Insights into Pathogenic Mechanisms
    • 1st Edition
    • Parissa Farnia + 3 more
    • English
    Structural and Functional Dynamics of Nontuberculous Mycobacterium Proteins: Insights into Pathogenic Mechanisms explores the structural and functional dynamics of nontuberculous mycobacterium (NTM) proteins, focusing on their roles in pathogenicity, the mechanisms underlying microbial infections, and the potential for developing targeted therapeutic strategies to combat these emerging pathogens. The book begins with a foundational overview of nontuberculous mycobacteria (NTM), distinguishing them from Mycobacterium tuberculosis, their epidemiology, clinical significance, and structural biology. It discusses key structural features of NTM proteins and advanced techniques for protein structure determination, proteomic analyses, and bioinformatics approaches.Additiona... sections investigate the pathogenic mechanisms and the complexities of the host-pathogen interaction. Concluding with insights into emerging research, interdisciplinary collaboration, future treatment, and prevention strategies, this book is a helpful resource for researchers and healthcare professionals engaged in the study of infectious diseases.

  • Empowering Health through Lifestyle Medicine

    The Essential Guide for Preventing and Managing Chronic Disease
    • 1st Edition
    • John Anthony Stevens
    • English
    Empowering Health through Lifestyle Medicine: The Essential Guide for Preventing and Managing Chronic Disease is an evidenced-based health discipline for use by anyone in the healthcare profession including clinicians and public health and for those researching illness prevention and chronic disease management to improve health research practice and patient outcomes. Combining the best available research with personal insights and experience and using the Lifestyle Medicine 6 pillar framework, the book engages readers not only in the description and efficacy of LM but also in the knowledge, concepts and behaviors to better prevent and manage nutrition, physical activity, stress, mental health as well our interaction with the environment for a healthier, happier life. This is a book should encourage clinicians to engage their patients more often and more practically with lifestyle medicine, and consumers to better engage with their clinicians, and to more effectively self-manage their own health in preventing and managing lifestyle-related illness for life.

  • Obesity

    Integrating Physiological, Pathophysiological and Clinical Perspectives
    • 1st Edition
    • Javier Gonzalez
    • English
    Obesity: Integrating Physiological, Pathophysiological and Clinical Perspectives, a volume in Elsevier's Hot Topics in Physiology series, provides coverage across a wide range of physiological disciplines, covering obesity science at a sufficient level to be understood by physiologists who may not be an expert in all subdisciplines, and with an aim of unifying physiological perspectives on obesity. Divided into three sections, the book covers causes of obesity (e.g., regulation of energy balance), the consequences of obesity (e.g., metabolic, disease risk etc.), and strategies to prevent and/or manage obesity (e.g., bariatric surgery, pharmacotherapy, and lifestyle).This volume is published in association with the International Union of Physiological Sciences (IUPS). It will be of great interest for clinicians, dieticians, exercise physiologists, and molecular biologists.

  • Electrocardiography of Laboratory Animals

    • 3rd Edition
    • Meg M. Sleeper + 1 more
    • English
    Electrocardiography of Laboratory Animals, Third Edition, is an essential resource for biological and medical researchers, veterinarians, zoologists, and students. With the increasing global emphasis on the ethical care and use of laboratory animals in research, this comprehensive guide provides a standardized approach to performing and analyzing electrocardiograms (ECGs) across all species used in today’s research. The book provides the latest information on critical topics such as safety electrocardiography, toxicology, safety pharmacology, and telemetry, ensuring that readers are well-equipped with the knowledge required for accurate ECG interpretation in preclinical studies. The book is carefully organized into detailed chapters, beginning with the fundamental principles of electrocardiography and its application in drug safety evaluation. It covers the electrocardiography of a wide range of laboratory animals, including rodents, guinea pigs, rabbits, cats, dogs, and various non-human primates such as marmosets, cynomolgus monkeys, rhesus monkeys, baboons, and chimpanzees. Additionally, it reviews the ECG characteristics of minipigs, nanopigs, and micropigs. The text also includes chapters on telemetry and echocardiography in preclinical safety studies, as well as discussions on important parameters like PR (PQ), QRS, and QT intervals. The book concludes with chapters on cardiac assays, biomarkers, stem cells, and cardiovascular medical devices, providing a holistic view of cardiovascular research. This enhanced and expanded Electrocardiography of Laboratory Animals, Third Edition offers invaluable insights and practical guidance, making it an indispensable tool for those involved in the care and study of laboratory animals. Its comprehensive coverage and detailed explanations ensure that readers can confidently conduct and interpret ECGs, thereby advancing the field of preclinical safety evaluation and contributing to the ethical and effective use of animals in research.

  • Biofeedback and Pain Management

    A Clinical Guide
    • 1st Edition
    • Anu Kotay
    • English
    Biofeedback and Pain Management: A Clinical Guide provides a detailed understanding of the psychophysiology of chronic pain, biofeedback treatments, the realities of living life with chronic pain limitations, and the role of pain in our lives and society. The book covers evidence on the effective uses of biofeedback interventions for pain management, including protocols, as well as case-based examples and strategies practitioners can use in real-life settings. Sections define biofeedback, including illustrations that depict how biofeedback is a useful part of any pain management treatment plan, cover procedures based on evidence and case examples, and present the social context of chronic pain.

  • Roles of the Cerebellum in Motor Control

    Foundations, Experimental Approaches and Clinical Applications
    • 1st Edition
    • Mario Manto + 2 more
    • English
    Roles of the Cerebellum in Motor Control: Foundations, Experimental Approaches and Clinical Applications is a groundbreaking, comprehensive reference on the intricate relationship between the cerebellum and motor function. Spanning five thorough sections, this book examines experimental approaches, from single neurons to networks, unraveling the mysteries of olivocerebellar somatotopy, motor prediction, and the cellular basis of motor learning. With chapters dedicated to neuroimaging, physiology, and pathophysiology, users will gain insight into the cerebellum's role in conditions such as tremor, dystonia, and Parkinson’s disease.From wearable sensors to digital gait biomarkers, various chapters offer a cutting-edge look at sensor technology and its application in assessing cerebellar function and rehabilitation. The book concludes with a discussion on research and clinical implications, providing a roadmap for translating laboratory findings into effective therapeutic strategies, making it an indispensable resource for researchers, clinicians, and students alike.

  • Diagnosis and Treatment of Infectious Diseases

    • 1st Edition
    • Saeed Soleiman Meigooni
    • English
    Diagnosis and Treatment of Infectious Diseases summarizes practical content in infectious diseases using keys topics for better coding and grasping of material. The book's author uses his experience from over 15 years of teaching and working in infectious diseases in more than ten hospitals with thousands of patients as a backdrop. All of its contents use a clinical perspective for a wide range of audiences, such as medical students, general practitioners, nurses, and others. As infectious diseases are among the most common diseases, and a cause of death in many societies, they can create health challenges in developed and developing countries.Medical students have a limited time for infectious diseases rotation in their curriculum and may not learn many infectious diseases syndromes during their entire medical course. Also, due to the high volume of infectious disease subjects in textbooks which overlap symptoms and signs of many microorganisms, they may forget some of the materials. Therefore, access to a comprehensive compact book such as this one seems necessary for any medical staff.

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