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Elsevier

Books in Life sciences

  • Sleep Neurology

    • 1st Edition
    • Anne Marie Morse
    • English
    Sleep Neurology explores the intricate relationship between sleep and neurological health, bridging the gap between theoretical knowledge and practical application. This comprehensive reference highlights the role of sleep in overall health and provides an examination of how sleep influences a wide range of neurological disorders. From neurodevelopmental issues to neurodegenerative diseases, this book offers a detailed review of how sleep science can be applied to improve patient outcomes in various neurological conditions. Structured around key neurological topics, the book offers insights into conditions such as epilepsy, stroke, and traumatic brain injury, emphasizing the importance of sleep management in their treatment. Each chapter not only discusses the scientific underpinnings of sleep but also provides tangible strategies for integrating sleep health into primary neurological care.

  • Wearable Biosensors for Healthcare

    Techniques and Applications
    • 1st Edition
    • Vigneswaran Narayanamurthy + 2 more
    • English
    Wearable Biosensors for Healthcare: Techniques and Applications is a comprehensive exploration of the transformative role of wearable biosensors in modern healthcare. The book explains the integration of artificial intelligence in health monitoring, showcasing how AI enhances data analysis and personalized health insights. Through practical case studies, sections illustrate real-world implementations across various healthcare domains, including chronic disease management, fitness tracking, and mental health monitoring. Additionally, it emphasizes the importance of interdisciplinary design principles, highlighting the need for collaboration among engineering, medicine, and data science to develop effective wearable solutions. Addressing technical challenges and proposing future research directions, this book serves as a vital resource for anyone interested in the intersection of technology and healthcare, ultimately aiming to inspire further innovation in the field of wearable biosensing.

  • Legal Issues in Quality for Healthcare Institutions

    • 1st Edition
    • Ramesh Sachdeva
    • English
    Legal Issues in Quality for Healthcare Institutions provides the perspective of practicing physicians, lawyers, and academic legal scholars to comprehensively address the implications for quality of care and patient safety both from a legal, medical, and improvement science standpoint. Hospital administrators, physicians, nurses, researchers, legal scholars, as well as regulatory and compliance officers working in hospitals and acute care facilities will find this to be a helpful resource in understanding and addressing the many facets and issues in the field of medicine and law related to quality and patient safety.

  • Drug Repurposing in Cancer Research

    • 1st Edition
    • Ranjita Shegokar + 1 more
    • English
    Drug Repurposing in Cancer Research investigates the innovative use of drug repurposing in oncology, focusing on emerging and re-emerging cancer types. The book provides a comprehensive yet concise overview of current trends, making it an essential resource for academics and professionals in the field. Structured into 21 chapters, the book presents foundational facts alongside practical and clinically relevant data. It covers topics ranging from market dynamics to AI-driven transformations in cancer treatment, highlighting the rapid advancements in oncology. This compilation ensures that readers are equipped with the latest information necessary for effective research and development. For pharmaceutical researchers, biomedical scientists, and clinicians, "Drug Repurposing in Cancer Research" offers valuable insights into the growing demand for innovative cancer treatments. It serves as a timely resource for understanding the potential of repurposed drugs, supporting efforts in cancer prevention and treatment strategies.

  • Urinary Incontinence

    Integrating Science and Clinical Practice
    • 1st Edition
    • Marcus Drake + 2 more
    • English
    Urinary Incontinence: Integrating Science and Clinical Practice succinctly describes the importance of lower urinary tract physiology to all for an understanding of urinary incontinence and its clinical treatment. World-leading contributors describe the key influences on mechanisms and therapies for proper understanding of the scientific basis of incontinence.The first part of the book is dedicated to System Physiology: Function and Adaptation. In this section, an anatomical sequence is followed for presenting the chapters, moving from the lower urinary tract organs upwards through the spinal centers to the brain. These chapters discuss what is known and unknown for crucial areas, such as neurological control and co-ordination, bladder fibrosis, bladder physiology and more.The second part is dedicated to Incontinence: Mechanism and Therapy. In this clinical application section, chapters derive from the clinical classification of incontinence and explore topics such as the role of urodynamics; mechanisms underpinning medical and interventional treatments; the sensations arising from the lower urinary tract; adverse effects of therapy and the considerable faced in managing incontinence.Written for researchers and clinicians, this book is a welcomed resource for those aiming to understand more about urinary incontinence.

  • Roles of the Cerebellum in Motor Control

    Foundations, Experimental Approaches and Clinical Applications
    • 1st Edition
    • Mario Manto + 2 more
    • English
    Roles of the Cerebellum in Motor Control: Foundations, Experimental Approaches and Clinical Applications is a groundbreaking, comprehensive reference on the intricate relationship between the cerebellum and motor function. Spanning five thorough sections, this book examines experimental approaches, from single neurons to networks, unraveling the mysteries of olivocerebellar somatotopy, motor prediction, and the cellular basis of motor learning. With chapters dedicated to neuroimaging, physiology, and pathophysiology, users will gain insight into the cerebellum's role in conditions such as tremor, dystonia, and Parkinson’s disease.From wearable sensors to digital gait biomarkers, various chapters offer a cutting-edge look at sensor technology and its application in assessing cerebellar function and rehabilitation. The book concludes with a discussion on research and clinical implications, providing a roadmap for translating laboratory findings into effective therapeutic strategies, making it an indispensable resource for researchers, clinicians, and students alike.

  • Next-Generation Food Bioactives

    Mechanisms, Technologies, and Translational Applications
    • 1st Edition
    • Karuppusamy Arunachalam + 3 more
    • English
    Next-Generation Food Bioactives: Mechanisms, Technologies, and Translational Applications offers a thorough examination of food-derived bioactive compounds such as polyphenols, flavonoids, polysaccharides, peptides, and saponins, and their significance in health promotion, disease prevention and the development of functional foods and nutraceutical products. Divided into six comprehensive sections, the book covers the fundamental properties of these compounds, advanced extraction and analysis methods, and explores their molecular mechanisms and interactions with the gut microbiome. Next-Generation Food Bioactives: Mechanisms, Technologies, and Translational Applications further discusses challenges related to bioavailability, safety, and regulatory considerations, while highlighting emerging trends such as the integration of artificial intelligence and omics technologies in bioactive discovery and functional food formulation. Designed for researchers, industry scientists, and healthcare professionals, this book provides valuable insights to support innovation and evidence-based development in the field of food bioactives.

  • Mechanobiology and Mechanomedicine

    From Fundamentals to Applications
    • 1st Edition
    • Lifang Hu + 2 more
    • English
    Mechanobiology and Mechanomedicine: From Fundamentals to Applications offers an in-depth investigation of the role mechanical stimuli plays in biological systems, from cellular behavior to disease development. Organized into three parts, the book initially covers the fundamentals of mechanobiology, exploring cellular and molecular mechanobiology including mechanical force types, mechanosensors and transducers, mechanosensitive signaling pathways and nuclear mechanotransduction. In addition, the application of finite element modeling techniques in studying multiscale mechanobiology of bone are included. The second section focuses on mechanobiology more broadly in health and disease, spanning its role across bone, cartilage, the dental and periodontal tissues, muscle, the cornea and sclera, and in airways. Each chapter considers the molecular and cellular mechanisms of mechanotransduction in these areas, as well as its significance for associated physiological and pathological conditions. The final section examines novel technologies like high-resolution mechanical imaging, organoids and artificial intelligence, concluding with the translational potential of mechanomedicine and its therapeutic applications.Mechano... and Mechanomedicine: From Fundamentals to Applications serves as a comprehensive and systematic overview of mechanobiology, sharing insights into the latest research advances and clinical relevance. Taking an interdisciplinary approach, this book is ideal for scientists, researchers and advanced students working across a range of areas including molecular biology, cell biology, translational medicine, biomechanics, biomedical engineering, biotechnology and related fields.

  • Theranostics for Cancer Targeting

    • 1st Edition
    • Ranjita Shegokar + 1 more
    • English
    This groundbreaking Theranostic book delivers the definitive roadmap for the next generation of precision oncology by systematically detailing the clinical, regulatory, and drug delivery landscapes of theranostics—the revolutionary integration of therapy and diagnostics—across 20-22 major cancer types. Designed for medical publishers, clinicians, and biotech researchers, this chapter is a structural framework for each malignancy, bridging laboratory breakthroughs in nanotechnology, green nanochemistry, drug delivery, diagnostics, and AI with real-world clinical applications. It serves as an essential commercial and academic asset, offering unprecedented depth on FDA/EMA regulatory hurdles, technology transfer pathways, and actionable data tables that track active clinical trials and global research groups. By addressing key market trends and regulatory challenges, it serves as an essential, multidisciplinary resource for driving personalized oncology and improving patient outcomes

  • Artificial Intelligence in Agricultural Systems

    Fundamentals and Advances
    • 1st Edition
    • Mohammad Mehdizadeh
    • English
    Artificial Intelligence in Agricultural Systems: Fundamentals and Advances focuses on advancements in AI in and draws upon the multi-faceted challenges of modern agriculture. This book curates the latest strands of AI applications that are reshaping agricultural systems, including current trends and emerging technologies. It offers an overview of the evolving agricultural landscape and foregrounds the critical role of AI in driving innovation and enhancing productivity in this essential sector. Organized into four parts, it introduces agricultural systems and AI fundamentals, including machine learning, deep learning, natural language processing, and robotics. It then pivots to data collection and processing techniques, explicating the use of sensors, IoT devices, remote sensing, and UAVs. Core applications in crop and livestock management receive emphasis, covering yield prediction, pest detection, precision irrigation, and sustainable farming practices. The final sections address the limitations of AI in agriculture, future trends, and policy recommendations, providing an overarching understanding of AI's responsible adoption. Artificial Intelligence in Agricultural Systems is an important resource for upper-level undergraduate and graduate students studying the impact of AI technologies on agriculture and food production. Researchers, practitioners, and policymakers studying the intersections of agriculture, environmental science, data science, and engineering will find this book compelling as well.

  • Quercetin in Drug Discovery

    • 1st Edition
    • Gautam Sethi + 2 more
    • English
    Quercetin in Drug Discovery is a detailed reference exploring the multifaceted pharmacological potential of quercetin, a naturally occurring flavonoid with significant therapeutic promise. Addressing the critical need for consolidated knowledge, this guide highlights quercetin’s diverse biological activities and the translational challenges limiting its clinical applications, making it essential for researchers and pharmaceutical scientists. The comprehensive table of contents covers quercetin’s pharmacological properties, molecular docking studies, and ADME profiles, alongside therapeutic applications in cardiovascular diseases, cancer, and other conditions. It further examines bioavailability enhancement strategies, drug formulation, innovative delivery systems, and clinical trial evidence. Contributions from leading experts provide detailed insights into signaling pathways, molecular targets, and synthetic derivatives. Quercetin in Drug Discovery equips pharmacologists, medicinal chemists, and pharmaceutical scientists with critical information to advance research and drug development. By addressing bioavailability issues and regulatory considerations, this reference supports the translation of quercetin from bench to bedside, fostering innovation in natural product-based therapeutics.

  • Biomaterials in Cancer Therapy

    Innovations and Applications
    • 1st Edition
    • Alok Raghav
    • English
    Biomaterials in Cancer Therapy: Innovations and Applications explores the critical role of functional biomaterials in addressing one of today’s most pressing health challenges—cancer. Despite advancements in therapies, cancer continues to claim millions of lives annually, necessitating innovative approaches that integrate engineering and pharmaceutical sciences. This book highlights the potential of engineered biomaterials to enhance drug delivery, minimize side effects, and promote tissue regeneration, ultimately improving patient outcomes. The content examines cutting-edge innovations in functional biomaterials, including their applications in targeted drug delivery and immunotherapy, while emphasizing the role of nanotechnology in developing effective cancer theranostics with minimal toxicity. Targeted at academicians, physicians, and industry professionals, this book serves as a vital resource for understanding the transformative potential of functional biomaterials in oncology. By addressing real-world challenges and incorporating diverse perspectives, it inspires innovative solutions that enhance global healthcare outcomes for cancer patients.

  • Management of Chronic Kidney Disease and Its Complications

    • 1st Edition
    • Thakur Gurjeet Singh + 4 more
    • English
    Management of Chronic Kidney Disease and Its Complications  presents the latest scientific advances in diagnosing and managing Chronic Kidney Disease (CKD) and its diverse complications. This authoritative text covers molecular mechanisms such as inflammation and oxidative stress, genetic and epigenetic factors, and explores cutting-edge technologies including artificial intelligence and regenerative medicine. With detailed chapters on cardiovascular, metabolic, neurological, and hematological complications, the book offers a holistic approach to understanding CKD’s complexity and evolving treatment strategies.The book’s content is organized to provide a thorough exploration of CKD, beginning with foundational topics like genetic contributions and diagnostic evaluation, progressing through specific complications such as diabetic nephropathy, hypertension, and urologic conditions. Special focus is given to management strategies, nutritional interventions, and unique considerations in pediatric, geriatric, and pregnant populations. Emerging therapies, including precision medicine, gut microbiota modulation, and AI-driven early detection, are also extensively covered to keep readers at the forefront of nephrology research and clinical practice.Management of Chronic Kidney Disease and Its Complications is an essential resource for nephrologists, general practitioners, medical students, nursing professionals, and healthcare providers involved in kidney disease care and research.

  • Principles and Practice of Nephrocardiology

    • 1st Edition
    • Parta Hatamizadeh
    • English
    Principles and Practice of Nephrocardiology provides a comprehensive introduction to the interdisciplinary subspecialty of Nephrocardiology. The book includes detailed descriptions, along with an in-depth exploration of its primary elements and topics. Coverage spans pathophysiology, epidemiology, prevention, diagnosis, prognosis, monitoring, therapy, risk factors, and the systemic diseases that involve both nephrology-related conditions and cardiovascular diseases. The book guides clinicians and general practitioners in multiple interdisciplinary specialties through diagnostic, preventive, and therapeutic approaches to a wide variety of patient populations. It also opens a myriad of new avenues for future research and guidance for approaching multiple medical topics.

  • Therapeutic Potentials of Tenofovir Alafenamide in Hepatitis B

    • 1st Edition
    • Lung-Yi Loey Mak + 1 more
    • English
    Therapeutic Potentials of Tenofovir Alafenamide in Hepatitis B offers a comprehensive examination of the therapeutic potentials of Tenofovir Alafenamide (TAF) in hepatitis B, providing a succinct and up-to-date summary of all relevant evidence for this first-line oral antiviral agent. The text delves into key topics such as the pharmacological profile of TAF, its comparative efficacy against traditional antiviral agents, safety and tolerability, and the impact of TAF on drug resistance. Additionally, it explores the use of TAF in special populations, including pediatrics, the elderly, and individuals with renal impairment, as well as future directions in hepatitis B treatment strategies.Readers will discover the diverse potential applications of TAF in chronic hepatitis B, informed by valuable lessons learned from HIV treatment while also gaining insights into future therapeutic possibilities. Authored by leading experts in the field, each chapter presents focused and insightful perspectives, making this book an indispensable resource for practitioners and researchers alike. Serving as a critical resource for physicians, researchers, pharmacologists, and biomedical scientists, this book highlights the core knowledge necessary for understanding TAF and its clinical applications.

  • The Kidney

    • 1st Edition
    • Volume 7
    • Ahmed El-Hashash + 1 more
    • English
    The Kidney, Volume Seven in the Stem Cell Innovation in Health and Disease series, explores the emerging potential of stem cell therapies in treating kidney diseases. With their natural regenerative and anti-inflammatory properties, stem cells offer a promising approach to restoring essential kidney functions and mitigating damage. This volume highlights how stem cell therapies may modulate immune responses, promote tissue repair, and replace damaged kidney cells, offering hope for chronic and acute renal conditions. Key developments include the injection of mesenchymal stem cells (MSCs) into damaged kidneys where they can differentiate into kidney cell types and aid in healing.In addition, urine-derived stem cells have also shown significant potential in improving kidney function in preclinical studies. Additionally, innovative techniques like incorporating MSCs into compact dialysis machines are explored, enabling delivery of pro-repair factors directly to the kidneys during blood filtration. While there are currently no FDA-approved stem cell treatments for kidney diseases, ongoing clinical trials aim to evaluate their safety and efficacy. This volume compiles cutting-edge research, discussing various cell sources, underlying mechanisms, observed therapeutic outcomes, and the practical challenges of clinical translation. By presenting a clear picture of current advances and future directions, this book serves as a vital resource for scientists, clinicians, and health innovators seeking to harness stem cell technology in nephrology.

  • Multiple Faces of Takotsubo Syndrome

    Clinical Presentations, Mechanisms and Advanced Diagnostic Insights
    • 1st Edition
    • Riccardo Cau + 1 more
    • English
    Multiple Faces of Takotsubo Syndrome: Clinical Presentations, Mechanisms and Advanced Diagnostic Insights offers a thorough review of Takotsubo syndrome and the role of advanced imaging techniques in improving diagnosis, monitoring, and management of this complex cardiac condition. The book begins with an introduction to Takotsubo syndrome, covering its historical background, prevalence, and key clinical characteristics. Subsequent chapters delve into epidemiology, risk factors, and psychological aspects, including the impact of COVID-19 and other viral infections. Then, clinical manifestations, management, prevention, and treatments are thoroughly discussed, along with complications and prognosis. The basic science section explores the pathophysiological mechanisms, the heart-brain axis, and multi-organ involvement.A significant focus throughout is placed on invasive and non-invasive imaging modalities, including angiography, echocardiography, cardiac MRI, computed tomography, and nuclear imaging. Future directions highlight emerging biomarkers and imaging techniques for personalized medicine, and real-world case studies provide practical insights for clinicians. The book offers invaluable benefits to scientists, researchers, and clinicians alike.

  • Laboratory Sleep Medicine

    Fundamentals of Sleep Technology
    • 1st Edition
    • Ravi Gupta + 2 more
    • English
    Laboratory Sleep Medicine: Fundamentals of Sleep Technology, is the second of the Fundamentals of Sleep Technology series, discusses balancing the fundamentals of sleep medicine with the newest innovations in the lab. High priority is given to practices that must be followed in sleep labs to guarantee the safety of patients and workers. To make information straightforward and easy to grasp, key events in each epoch of polysomnography are showcased. This serves to walk sleep professionals cogently through the history of sleep technology advancement.Laborato... Sleep Medicine: Fundamentals of Sleep Technology is keenly aware that manual titration with PAP is the gold standard treatment for sleep apnea. However, certain patients may require oxygen treatment, which is also covered in depth. In addition, case vignettes illustrate the development of a relevant report using the following: data from a sleep diary, actigraphy, and polysomnography. How to do sleep tests in unusual situations (such as at-home sleep apnea testing and testing in an intensive care unit) are also covered.

  • Microfluidic Platforms for Rapid Antibiotic Susceptibility Testing (AST)

    Accelerating Diagnosis and Optimizing Antimicrobial Therapy
    • 1st Edition
    • Raju Khan + 4 more
    • English
    Microfluidic Platforms for Rapid Antibiotic Susceptibility Testing (AST): Accelerating Diagnosis and Optimizing Antimicrobial Therapy provides a comprehensive and interdisciplinary exploration of microfluidic technologies as transformative tools in the fight against antimicrobial resistance (AMR). By integrating foundational knowledge of AMR and microfluidics with cutting-edge research, it offers readers an in-depth understanding of how microfluidic systems enable rapid, precise, and cost-effective antibiotic susceptibility testing (AST). The book addresses both the scientific principles and practical applications of these technologies, emphasizing their potential to revolutionize diagnostics, personalize treatment, and improve global health outcomes amidst the growing threat of drug-resistant infections. Organized into five key parts, the book begins with an overview of the global challenge of antimicrobial resistance and the fundamental principles of microfluidics in biomedical contexts. It then delves into various microfluidic platforms for AST, including continuous flow and droplet-based systems, as well as single-cell trapping techniques. Subsequent chapters focus on diverse detection methods—optical, electrochemical, and acoustic—for monitoring bacterial growth and antibiotic response. The book further explores specialized approaches such as paper-based point-of-care devices, biosensing strategies, and personalized medicine applications. The final section addresses clinical translation, covering validation, regulatory considerations, device design, automation, emerging technologies, ethical guidelines, and future perspectives on microfluidic AST’s role in combating antimicrobial resistance worldwide.

  • Advances in Noncoding RNA Diagnostics and Therapeutics in Immunity and Cancer

    • 1st Edition
    • Afsar Naqvi + 1 more
    • English
    Advances in Noncoding RNA Diagnostics and Therapeutics in Immunity and Cancer explores the critical role of noncoding RNAs in immune-mediated diseases and cancers, providing an essential resource on their diagnostic and therapeutic potential. The book contributes valuable insights into the pathobiology of noncoding RNAs and their application in various diseases, delving into the latest research on noncoding RNAs, including their mechanisms, interactions, and roles in disease. In addition, it examines how noncoding RNAs influence immune responses, inflammation, and cancer progression. With a focus on both diagnostic and therapeutic applications, this book highlights the potential of noncoding RNAs as biomarkers and therapeutic targets. Across comprehensive chapters, the book covers a wide range of topics, including the role of virus-encoded microRNAs in immune evasion, the therapeutic aspects of non-coding RNA in hepatocellular carcinoma, the impact of microRNAs in periodontal inflammation, and the involvement of miRNAs and lncRNAs in regulating the tumor microenvironment in HCC. Other chapters explore the functions and clinical value of tumor-derived exosomes and miRNAs in cancer immune response, the interaction of noncoding RNA in cancer metastasis, and a panorama of non‐coding RNA in prostate cancer. This book is an invaluable resource for basic science researchers in the noncoding RNA field, cancer biologists, immunologists and RNA biologists interested in the latest advancements in noncoding RNA research.

  • Baleen Whales

    Ridgway and Harrison's Handbook of Marine Mammals: Volume 4
    • 1st Edition
    • Thomas Allen Jefferson
    • English
    Some of the world's most beautiful, intelligent, and highly adapted mammals inhabit our seas and oceans and have stirred the human imagination for many centuries. As our knowledge of marine mammals grows, the need exists for a reliable and complete reference to the ecology and biology of these fascinating creatures. To address this need, the Handbook of Marine Mammals series has been founded. Scientists, conservationists, and informed laypersons alike will be able to find definitive reviews of all the world's living whales, dolphins, porpoises, seals, sea lions, sea cows, and marine otters and bears. Seven volumes cover all the living species of marine mammals.This fourth volume in the series, Baleen Whales, consists of species review chapters written by leading global experts on whale species that have baleen plates instead of teeth. Each chapter includes a description of the species, followed by sections on distribution and abundance, anatomy, physiology, behavior, ecology, reproduction, parasites and diseases, and the impacts of human activities on the species.

  • Advances in Design of Microbial Cell Factories

    • 1st Edition
    • Dibyajit Lahiri
    • English
    Advances in Design of Microbial Cell Factories presents a comprehensive overview of the latest innovations in engineering microbial platforms for sustainable production of biochemicals, biofuels, pharmaceuticals, and industrial enzymes.The book opens with an introduction and historical overview of microbial cell factories, followed by a wide spectrum of topics including omics-driven design and engineering of microbial cell factories, metabolic flux analysis, genome-scale metabolic modeling, modular pathway engineering, biosensors, adaptive laboratory evolution, protein engineering and enzyme optimization in microbial hosts. The latest developments in designing bacterial, yeast, mold and microalagae cell factories are covered, as well as current challenges to be considered in scale-up of microbial cell factories. Chapters are supported by real-world case studies that demonstrate translation from laboratory research to industrial-scale applications across a diverse range of sectors.This reference consolidates foundational knowledge with emerging technologies, equipping researchers, graduate students, and industry professionals with practical insights to accelerate their own development of microbial platforms.

  • Plant Development

    • 1st Edition
    • Volume 172
    • English
    Plant Development provides an overview of the fundamental processes that govern the growth, differentiation, and organization of plants throughout their life cycle. The book explores key developmental stages, from embryogenesis and seed germination to organ formation, flowering, and senescence, highlighting the genetic, molecular, cellular, and environmental factors that regulate these events. By integrating classical concepts with modern advances in developmental biology, the volume offers valuable insight into how plants establish form, adapt to their surroundings, and coordinate growth in response to internal and external signals. It serves as a useful resource for researchers, students, and professionals interested in plant biology, developmental mechanisms, and related fields.

  • Synthetic Biology in Medicine

    Tools and Transformative Therapies
    • 1st Edition
    • Xie Zhen
    • English
    Synthetic Biology in Medicine: Tools and Transformative Therapies covers the design and optimization of artificial biological components, gene editing systems, principles for designing and constructing artificial gene circuits, cell engineering, delivery systems of artificial biomolecules, and the prospects and challenges of synthetic biology technologies applied in drug development. The book contains many application cases related to clinical practice and industry, offering references for solving industrial pain points.

  • Nanotechnology in Brain Tumor Treatment

    Unveiling Molecular Mechanisms and Pioneering Therapies
    • 1st Edition
    • Arun Kumar Singh + 4 more
    • English
    Nanobiotechnology in Brain Tumor Treatment: Unveiling Molecular Mechanisms and Pioneering Therapies is a groundbreaking resource that addresses the formidable challenges posed by brain tumors in oncology. This comprehensive book explores the etiology, symptoms, diagnosis, and treatment options for brain tumors, with a particular focus on the revolutionary impact of nanobiotechnology. By integrating cutting-edge research on nanotechnology with practical applications in neuro-oncology, this book offers a unique perspective on enhancing patient outcomes and advancing brain cancer treatment strategies.By offering a comprehensive overview of nanobiotechnology in brain tumor treatment, this resource serves as a vital tool for those involved in the research, diagnosis, and treatment of brain cancers, paving the way for innovative and personalized therapeutic approaches.

  • Neurogenetic Therapies

    Advancements in Treating Nervous System Disorders
    • 1st Edition
    • Ashutosh Pareek + 4 more
    • English
    Neurogenetic Therapies: Advancements in Treating Nervous System Disorders offers a comprehensive resource on the latest gene therapy techniques and their applications in treating neurological disorders. The book delves into various gene therapy methods, including genomic DNA-based therapies, vector-mediated delivery, and RNA interference-based gene silencing. It explores the use of these techniques in treating conditions such as Alzheimer's disease, Parkinson's disease, spinal muscular atrophy, and Duchenne muscular dystrophy. Key topics include the molecular and genetic basis of nervous system disorders, the role of epigenetics, and the development of stem cell and genome editing therapies.With contributions from leading experts, the book also addresses regulatory and ethical considerations in gene therapy, providing a balanced perspective on the challenges and opportunities in this rapidly evolving field. Case studies and practical examples illustrate successful gene therapy treatments, offering valuable insights into translating research into clinical practice. This book is an essential resource for students, researchers, and scientists in neurogenetics, neurology, and molecular biology, as well as clinicians interested in the mechanisms and treatment of neurodegenerative diseases.

  • Human-AI Interaction for Digital Healthcare Systems

    • 1st Edition
    • Jinwoo Kim
    • English
    Human-AI Interaction for Digital Healthcare Systems defines Human‑AI Interaction (HAII) as the next evolutionary phase of Human‑Computer Interaction, addressing the shift from reactive systems to proactive AI agents. Using digital healthcare as its primary application domain, it introduces a rigorous, evidence‑based methodology for designing AI systems that are effective, safe, and trusted in real‑world clinical contexts. The text integrates the Sensing–Reasoning–Ac... (SRA) loop into human‑centered design, balancing system efficacy with environmental conformance. It provides structured guidance across the full lifecycle, analysis, planning, design, and evaluation,ensuring AI systems deliver measurable clinical and user value. Beyond theory, the book emphasizes empirical validation, detailing controlled experiments (e.g., RCTs) and real‑world performance analysis using Real‑World Data (RWD) and Real‑World Evidence (RWE), with explicit consideration of regulatory requirements for Software as a Medical Device (SaMD).

  • Understanding Molecular Processes using Electrochemical Methods

    • 1st Edition
    • Ashis Kumar Satpati + 1 more
    • English
    Understanding Molecular Processes using Electrochemical Methods offers a detailed compendium of techniques for molecular analysis. The book considers step and sweep techniques, scanning electrochemical microscopy, spectroelectrochemic... techniques, electrochemiluminesc... and scanning probe techniques while also exploring COSMOL multiphysics simulation, electroanalysis in biomedical and clinical applications, and future prospects for electrochemical techniques. Chapters focus on evaluating redox reactions, biological interactions, kinetics, quorum sensing, biofilm formation, surface modification and more molecular aspects. This volume offers a deep-dive into the fundamental principles behind the latest electrochemical techniques, equipping researchers with practical guidance for their own experiments.Users will find this to be an ideal reference for researchers working across a range of disciplines including molecular biology, bioanalytical chemistry, biomedical science, and translational medicine.

  • 3D Bioprinting and Bio-Regenerative Medicine for Personalized Oncology

    Innovations for Personalized Oncology
    • 1st Edition
    • Ashok Kumar + 2 more
    • English
    3D Bioprinting and Bio-Regenerative Medicine for Personalized Oncology: Innovations for Personalized Oncology presents a comprehensive exploration of the transformative role of 3-D bioprinting and bio-generative engineering in modern medicine, with a specific focus on precision oncology. By examining innovative applications of these technologies, the book aims to bridge the gap between emerging scientific advancements and their practical implications in clinical settings. It delves into how patient-specific models of human tissues and organs can revolutionize drug testing, disease diagnostics, and personalized treatment plans, ultimately enhancing the quality of cancer care.Addressing critical challenges in oncology, this book highlights how 3-D bioprinting and bio-generative engineering can improve the accuracy of drug efficacy evaluations, reduce reliance on animal testing, and tackle the pressing issue of organ shortages for transplantation. Furthermore, it emphasizes the ethical considerations and regulatory challenges associated with integrating these technologies into everyday oncology practice, ensuring a balanced perspective on their adoption.

  • Prokineticins

    From the Gastrointestinal Tract to Neuroinflammation
    • 1st Edition
    • Roberta Lattanzi + 1 more
    • English
    Prokineticins: From the Gastrointestinal Tract to Neuroinflammation explores the intricate biology and pathophysiological roles of prokineticin peptides, from developmental processes in the heart and brain to the regulation of homeostasis in health and disease. Beginning with an introduction to prokineticins, the book moves on to discuss physiological functions across the human body, including the regulation of circadian rhythm, food intake, heart and kidney function and the reproductive system. Chapters then cover the prokineticin system in neurogenesis dysfunction, obesity and diabetes, reproductive system disorders and cardiovascular diseases.The prokinetcin system is also explored in the context of neurodegenerative disease and traumatic brain injury, pain, inflammation, infection and cancer. It also investigates natural and pharmacological inhibitors of PK receptors and closes with a look towards future research perspectives.

  • Molecular Insights for Harnessing Urine Biomarkers in Precision Medicine

    • 1st Edition
    • Cheng Xue + 4 more
    • English
    Molecular Insights for Harnessing Urine Biomarkers in Precision Medicine provides a comprehensive exploration into the molecular signatures and clinical implications of urine biomarkers, providing invaluable insights for clinicians, researchers, and healthcare professionals.From historical perspectives to cutting-edge technologies, this reference presents an updated understanding of urine biomarkers' role across diverse bodily systems. With sections devoted to fundamental concepts, molecular signatures, and clinical applications, readers gain a deep understanding of urine biomarkers' significance in disease diagnosis and personalized medicine. Each chapter explores specific body systems, including renal, urological, cardiovascular, and respiratory, uncovering the diagnostic potential of urine biomarkers in various conditions like cancer, cardiovascular diseases, and neurological disorders. Highlighted are the latest advances in technology, challenges, and future directions, keeping readers abreast of the rapidly evolving landscape of urine biomarker research. Real-world case studies illustrate practical applications, enhancing comprehension and facilitating knowledge transfer to clinical practice.

  • Geographic Atrophy in Age-related Macular Degeneration

    • 1st Edition
    • Jay Chhablani + 1 more
    • English
    Geographic Atrophy in Age-related Macular Degeneration provides a comprehensive resource on this flourishing discipline, focusing on accurate diagnosis, imaging features, clinical trials, differential diagnoses, and both established and emerging treatment options. The book details diagnostic processes using techniques such as visual acuity tests, dilated eye exams, fundus photography, optical coherence tomography (OCT), and fluorescein angiography, emphasizing the importance of early detection. It also differentiates geographic atrophy from other retinal conditions with similar symptoms, such as dystrophies, equipping practitioners with the knowledge for accurate diagnosis.Additional... it explores traditional management approaches like antioxidant supplements, lifestyle changes, and low vision aids, alongside novel treatments such as complement inhibitors, cell-based therapies, and gene therapy, to inform clinicians about the latest advancements and research in patient care. With the recent FDA approval for GA treatment, there has been significant interest in the retina community. This rapidly growing field necessitates a new book on geographic atrophy in age-related macular degeneration to address gaps in existing literature and provide up-to-date, comprehensive information.

  • Rare and Complex Liver Diseases

    • 1st Edition
    • Ansgar Wilhelm Lohse + 2 more
    • English
    Rare and Complex Liver Diseases is a comprehensive guide that fills a critical gap in the literature, providing up-to-date, practical advice. The book is organized into distinct sections, each dedicated to a specific category of liver diseases. Topics covered include Autoimmune Liver Diseases such as Autoimmune Hepatitis (AIH) and Primary Biliary Cholangitis (PBC); Cholestatic Liver Diseases including Biliary Atresia and Alagille Syndrome; Vascular Liver Diseases like Budd-Chiari Syndrome and Non-cirrhotic Portal Hypertension; Metabolic Liver Diseases such as Wilson Disease and Alpha-1 Antitrypsin Deficiency; Structural Liver Diseases including Polycystic Liver Disease; and Rare Liver Tumors like Cholangiocarcinoma and Hemangioendothelioma... chapters cover Liver Disease in Pregnancy and delve into Quality of Life issues, offering evidence-based insights and practical strategies for improving patient well-being. This book serves as an indispensable resource for gastroenterologists, hepatologists, internists, and researchers specializing in liver diseases. It equips these professionals with the knowledge and practical advice necessary to improve patient outcomes and advance their field of study.

  • Transesophageal Echocardiography

    Basic and Advanced Aspects and Clinical Field of Application
    • 1st Edition
    • Antonello D’Andrea
    • English
    Transesophageal Echocardiography: Basic and Advanced Aspects and Clinical Field of Application provides clinicians and echocardiography professionals with a thorough and practical resource covering both the fundamental principles and advanced clinical uses of TEE. It benefits the audience by delivering step-by-step guidance on image acquisition, interpretation of valve and ventricular pathology, and real-world applications in perioperative, emergency, and interventional settings. Richly illustrated and supplemented by instructional videos, the book’s contents include diagnostic techniques, perioperative management, assessment of prosthetic and congenital heart conditions, and specialized topics such as TEE in sports cardiology and critical care—empowering readers to improve patient outcomes and master the latest advancements in cardiovascular imaging.

  • Current Research on Biofilm-Mediated Chronic Diseases

    Immunological Background and Clinical Interpretations
    • 1st Edition
    • Dibyajit Lahiri + 3 more
    • English
    Current Research on Biofilm Mediated Chronic Diseases: Immunological Background and Clinical Interpretations is an in-depth exploration of the complex interplay between biofilms, the immune system, and chronic diseases. These microbial communities, encased in self-produced extracellular polymeric substances (EPS), adhere to surfaces and resist environmental stresses, including host immune responses and antimicrobial agents.This comprehensive book investigates the formation, characteristics, and profound impact of biofilms on human health. Coverage spans the fundamentals of biofilm formation, immune evasion, and antimicrobial resistance (AMR); the role of biofilms in chronic diseases including periodontal disease, chronic wounds, and respiratory and urinary tract infections; their involvement in cancer development and neural disorders via the gut-brain axis; emerging therapeutic strategies such as nanotechnology, phage therapy, and immunomodulatory approaches; and the growing application of artificial intelligence (AI) and machine learning to biofilm-immune interactions and personalized medicine.Current Research on Biofilm Mediated Chronic Diseases: Immunological Background and Clinical Interpretations provides essential insights for researchers, undergraduates, and postgraduates seeking to understand and combat the challenges posed by biofilms in chronic disease pathology. This book offers valuable knowledge on recent techniques for detecting and mitigating antimicrobial resistance (AMR) and biofilm formation, making it an indispensable resource for scientists and clinicians alike.

  • Zebrafish Model of Neurodegenerative Disorders

    Knowing the Unknown
    • 1st Edition
    • Wael Mohamed
    • English
    Zebrafish Model of Neurodegenerative Disorders: Knowing the Unknown reveals a ground-breaking method for decoding neurodegenerative disorders such as Parkinson's, Alzheimer's, ALS, and Huntington's through the lens of the zebrafish. This volume bridges the divide between fundamental science and clinical innovation, demonstrating how the genetic malleability, transparent embryos, and conserved neural pathways of zebrafish provide unparalleled insights into neurodegeneration. It illustrates the potential to uncover concealed pathological mechanisms, expedite drug discovery, and surmount the translational failings that impede current research using this gold-standard model species. Featuring contributions from global experts, this volume is systematically structured into five topical sections for ease of navigation. These sections explore the role of cutting-edge tools such as CRISPR-Cas9, AI-driven phenotyping, and high-throughput drug screening in the study of α-synuclein aggregation in Parkinson's Disease and amyloid-β toxicity in Alzheimer's Disease. The volume offers real-world applications, comparative analyses of zebrafish and mammalian models, and actionable protocols that translate zebrafish discoveries to clinical trials. Zebrafish Model of Neurodegenerative Disorders is designed to empower researchers, clinicians, and healthcare professionals by addressing existing gaps in knowledge, particularly fragmentation in protocols and the translational disconnect between preclinical models and human trials. By fostering an integrated understanding of zebrafish as a model for neurodegeneration, it enhances research reproducibility, accelerates drug discovery, and promotes ethical, scalable research practices. Whether used as a teaching resource or a reference for experimental design, this volume offers invaluable insights to advance the understanding and treatment of devastating neurodegenerative diseases.

  • Endometriosis and Associated Pain

    Bridging Theory and Practice
    • 1st Edition
    • Chi Chiu Wang
    • English
    Endometriosis and Associated Pain: Bridging Theory and Practice is a comprehensive professional resource comparing Eastern and Western perspectives on endometriosis-relate... pain and co-morbidities. It addresses a significant gap by summarizing clinical, pathological, and social aspects, highlighting strengths and weaknesses in both traditions synthesizing existing evidence. The book targets basic science researchers and clinicians in women’s health, reproductive biology, and pain medicine, providing detailed reviews, recent developments, and future directions. Structured into six sections covering clinical features, pathology assessments, treatments, alternative therapies, and global health guidelines, bringing together extensive expertise in reproductive medicine. This book is a vital, up-to-date reference for professionals seeking a cross-cultural understanding of endometriosis pain management.

  • Animal Stress Biology

    Applications across Natural and Man-made Systems
    • 1st Edition
    • Edward Narayan
    • English
    Animal Stress Biology: Applications across Natural and Man-made Systems provides the fundamental aspects of stress endocrinology with a major focus on the applications of stress research in animal welfare. Early sections introduce the basics of animal stress biology in major taxa. Latter sections explore how animal stress varies across species and settings and how this research can be applied to improve animal welfare. The book incorporates chapter summaries, key term definitions, global case studies, and discussion sections throughout, making it an indispensable resource to students and early career professionals, as well as specialists in agriculture, zoos, clinical research settings, and resource management.Stress plays an integral part in the maintenance of homeostasis in animals and is a useful measure of animal responses to management interventions across natural, agricultural, and clinical settings. Written by experts in the field of animal stress biology, this book is systematically structured for easy student navigation.

  • The Human Nervous System

    • 4th Edition
    • George Paxinos + 2 more
    • English
    The 4th Edition of the classic book The Human Nervous System continues to assemble contributions from world leaders in research on the brain, spinal cord and peripheral nervous system. This book has been edited by the best-known team of brain cartographers, and it has been completely revised to present the cutting edge of human neuroscience. The structure, connections and function are explained in depth, making this book essential to any student or scientist interested in brain anatomy and function.

  • RNA-binding Proteins Part C

    • 1st Edition
    • Volume 745
    • English
    This volume of Methods in Enzymology presents a practical and multidisciplinary collection of contemporary methods for investigating RNA biology, RNA-binding proteins (RBPs), RNA–protein interactions, ribonucleoprotein (RNP) complexes, biomolecular condensates, liquid–liquid phase separation, RNA processing, translation, and RNA-mediated regulation. The chapters integrate complementary experimental and computational approaches, including biochemical reconstitution, quantitative microscopy, transcriptomics, proteomics, interactomics, NMR spectroscopy, structural biology, computational analysis, and tissue-based techniques.Together, these methods provide a versatile framework for elucidating how RNA and RBPs regulate cellular organization, gene expression, RNA metabolism, RNA processing, translation, and biomolecular phase behavior. Particular emphasis is placed on emerging applications in disease-associated molecular pathways, including neurodegeneration and neurological disorders, with coverage of topics relevant to Alzheimer’s disease, Tau biology, and HIV-associated neurocognitive disorders. This volume provides researchers with practical methodological strategies for dissecting RNA–protein interactions and defining RBP function across molecular, cellular, and disease contexts. The collection is designed to serve as a valuable methodological resource for researchers investigating the mechanisms by which RNA–protein networks govern cellular processes and contribute to human disease.

  • Protein Misfolding

    • 1st Edition
    • Timir Tripathi
    • English
    Protein Misfolding explores the structural and biochemical foundations of protein misfolding, highlighting its wide-reaching implications for cellular function, disease progression, and biomedical innovation. This book provides a comprehensive understanding of how proteins deviate from their native conformations and the resulting biological consequences. Focusing on both physiological and pathological misfolding, the volume covers essential topics such as folding quality control, molecular chaperones, degradation pathways, and proteostasis. It presents in-depth analyses of protein aggregation mechanisms, amyloid formation, and misfolding-associate... diseases including Alzheimer's, Parkinson's, and prion-related disorders. Additional chapters explore structural approaches to understanding misfolded states, computational modeling of aggregation kinetics, and current efforts to design therapeutics that restore folding homeostasis or prevent toxic accumulation. The book also addresses the cellular response to misfolding stress and the integration of folding dynamics with cellular signaling pathways.This book is a valuable resource for researchers, educators, and professionals in biochemistry, structural biology, molecular medicine, biotechnology, and related disciplines. It supports efforts to understand the fundamental principles of protein structure and function, while offering insight into emerging therapeutic strategies and future research directions in disease-focused protein science.

  • CRISPR Therapeutics Delivery Strategies

    • 1st Edition
    • Prashant Kesharwani
    • English
    CRISPR Therapeutics Delivery Strategies is a structured and comprehensive resource in the rapidly evolving field of CRISPR technology. As CRISPR-Cas systems translate to therapeutics, this reference provides critical insights into the challenges and advancements in effective delivery mechanisms. The book captures the essence of CRISPR's transformative potential in gene therapy, targeted cancer treatments, and personalized medicine, while also highlighting the importance of innovative delivery strategies to overcome existing barriers. The contents of the book offers a systematic exploration of CRISPR technology, beginning with foundational concepts and progressing to targeted drug delivery strategies. Each chapter explore specific applications, including CRISPR in cancer therapy, gene editing for rare diseases, and overcoming delivery barriers such as the blood-brain barrier. Additionally, ethical and regulatory considerations are addressed, providing a holistic view of the current landscape and future directions in CRISPR research. CRISPR Therapeutics Delivery Strategies serves as an essential resource for students, researchers, and professionals in the fields of pharmacology, biotechnology, and gene therapy. By compiling cutting-edge research and expert perspectives, this reference helps pharmaceutical scientists to navigate the complexities of CRISPR technology and its applications.

  • Network Pharmacology

    Exploring New Horizons in Drug Discovery
    • 1st Edition
    • Veeranoot Nissapatorn + 4 more
    • English
    Network Pharmacology: Exploring New Horizons in Drug Discovery explores the innovative network pharmacology approach—which examines the intricate interactions between disease targets and metabolites—offering a systems-based perspective that is essential for modern drug discovery. Readers will find in-depth discussions on metabolite databases, computational tools, and the role of natural products in drug discovery. Notable topics include network-based approaches to drug repurposing, personalized medicine, and the implications of traditional medicine in pharmacological research, all supported by real-world case studies and advanced computational methodologies.By integrating multiomics data, including metabolite profiling, the book addresses the limitations of conventional methods and opens new pathways for understanding disease mechanisms and therapeutic responses. This is a foundational guide for researchers, pharmaceutical scientists, and academic scholars across diverse fields such as pharmacology, metabolomics, and systems biology.

  • Advances in Nanocarriers for Biofilm-Associated Infections

    From Research to Clinical Practice
    • 1st Edition
    • Neeraj Mishra + 2 more
    • English
    Advances in Nanocarriers for Biofilm-Associated Infections: From Research to Clinical Practice addresses the critical challenge of treating biofilm-associated infections, which are resistant to conventional antibiotics due to their protective microbial communities. This reference compiles cutting-edge research on nanocarriers, including nanoparticles, liposomes, dendrimers, and polymeric micelles, emphasizing their design and application to penetrate biofilms and enhance antimicrobial delivery. The comprehensive content covers biofilm formation, resistance mechanisms, and multidrug resistance, followed by detailed chapters on nanocarrier synthesis, functionalization, and therapeutic efficacy. Clinical and translational aspects are examined through case studies on chronic wounds, medical device infections, and respiratory biofilms, alongside regulatory hurdles and future research directions. The book features contributions from international experts, providing a multidisciplinary perspective on nanotechnology’s role in infection control.It equips researchers, clinicians, and pharmaceutical professionals to understand complex biofilm biology, apply novel drug delivery systems, and navigate clinical challenges, ultimately supporting the development of improved treatments for persistent biofilm-related infections.

  • Central Nervous System Viral Infections

    • 1st Edition
    • Karen L. Roos + 1 more
    • English
    Central nervous system viral infections pose one of the greatest threats to humanity, as evidenced by recent history with SARS-CoV-2 (COVID 19), HIV, and others. Understanding their effects, therapeutics, and prevention are a top priority for all. "Central Nervous System Viral Infections" reviews the mechanisms of viral infections, current viruses of interest, diagnosis, course, and therapeutics, as well as prevention. Post infection syndromes and complications are also reviewed. Coverage includes Covid, HIV, Zika, EBOLA, Marburg, Herpes, Measles, Mumps, Polio, and more.

  • The Neurobiological Underpinnings of Addiction Medicine

    Focusing on Novel Approaches
    • 1st Edition
    • Mohammad Shabani + 3 more
    • English
    The Neurobiological Underpinnings of Addiction Medicine: Focusing on Novel Approaches provides a comprehensive review of the biological mechanisms that drive addiction and innovative strategies for treatment. This book begins by examining the crucial role of the microbiome and the gut-brain axis in various substance use disorders, including opioid, alcohol, neurostimulant, and cannabis use disorders. It highlights how gut health can significantly influence addiction behaviors and treatment outcomes. Following this, the second section discusses the interplay between addiction and neuropsychiatric disorders such as depression, anxiety, schizophrenia, ADHD, bipolar disorder, PTSD, and OCD.This section emphasizes the impact of neurotransmitter systems and intracellular pathways on the development and persistence of these disorders. The final section introduces cutting-edge methodologies reshaping addiction research, including multi-OMICS approaches and the implications of CRISPR-Cas9 technology. By integrating these diverse topics, this book offers vital insights for clinicians and researchers alike.

  • Plant Peptides

    Enzymatic Production and Health-Promoting Effects
    • 1st Edition
    • Tolulope Joshua Ashaolu + 2 more
    • English
    Plant Peptides: Enzymatic Production and Health-Promoting Effects provides up-to-date insights on the enzymatic production, bioactivity, and applications of plant-derived peptides. This comprehensive volume explores the role of plant-based proteins (PBPs) as sustainable alternatives to traditional animal proteins, highlighting their environmental and climatic benefits. The book examines the enzymology of proteolytic enzymes used to generate bioactive peptides from PBPs, detailing their bioaccessibility, stability, and bioavailability. It offers an in-depth analysis of the multifarious biological activities of these peptides, including their antioxidant, antimicrobial, and metal-binding properties. The book also addresses the technological and biological properties, limitations, and challenges of plant-based bioactive peptides for industrial uses.With a strong focus on practical implementation, the book discusses emerging strategies and advanced technologies for producing and analyzing bioactive peptides, such as in silico analysis, fermentation, and peptidomics. It provides insights into future research directions and potential applications, emphasizing the health-promoting effects of plant-based peptides in combating obesity, diabetes, hypertension, cancer, and neurodegenerative diseases. This book is an essential resource for food science researchers, nutritionists, and students of food science and nutrition.

  • Lanzkowsky's Manual of Pediatric Hematology and Oncology

    • 8th Edition
    • Jonathan D. Fish + 2 more
    • English
    Lanzkowsky's Manual of Pediatric Hematology and Oncology, Eighth Edition covers a wide array of topics, from molecular and genomic methodologies to specific hematologic disorders and various types of cancer, along with supportive care strategies. Each chapter is authored by leading experts who provide the latest evidence-based practices, diagnostic techniques, and treatment modalities, ensuring that practitioners have access to authoritative insights for informed clinical decision-making. This manual offers the tools and strategies necessary for delivering high-quality, evidence-based care, ultimately enhancing patient outcomes and improving the quality of life for young patients.Whether you are a trainee, an early-career physician, or a seasoned practitioner, this manual is an indispensable reference that will support your journey in pediatric hematology and oncology.

  • Basic Neurochemistry

    Principles of Molecular, Cellular, and Medical Neurobiology
    • 9th Edition
    • Scott Brady + 1 more
    • English
    Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, Ninth Edition is a classic advanced neurochemistry and neurobiology textbook that has a renewed focus on clinical applications. The early chapters focus on fundamental membrane chemistry, cellular signaling, and development of the nervous system. Later chapters cover cell injury and inflammation, neurodegenerative diseases, sensory transduction, and neural processing/behavior. By understanding mechanisms at the molecular and systems level, scientists can develop new pharmacotherapies to treat diseases such as Alzheimer's Disease, Parkinson's Disease, Multiple Sclerosis as well as neuropsychiatric diseases (e.g., schizophrenia, depression, pain, addictions).This book provides a foundation of all key principles of neurochemistry and neurobiology--within the context of human diseases--for advanced students and graduate students in neuroscience, biomedical sciences, as well as clinical neuroscientists and neurologists.

  • Tourette Syndrome and Other Tic Disorders

    • 1st Edition
    • Mariam Hull
    • English
    The Neuroscience of Tourette's Syndrome and Other Tic Disorders provides a foundation of the latest research into tic disorders and the brain, as well as including a comprehensive framework for the evaluation of tics. Authors across multiple specialties present the most thorough and latest knowledge of Tourette syndrome to include underlying pathophysiology, clinical presentation, how to differentiate it from other tic disorders, particularly functional tics. Clinical case studies will also feature throughout to outline challenging cases with expert commentary on evaluation and management strategies.

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