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Books in Life sciences

  • Microbial Crosstalk with Immune System

    New Insights in Therapeutics
    • 1st Edition
    • Asmita Das
    • English
    Our body is not sterile and harbors enumerable microflora that are now being understood to play a complex role in immune regulation and shaping of the immune system in a continuous and dynamic way. In 8 chapters, Microbial Crosstalk with Immune System: New Insights in Therapeutics provides an overall introduction with special focus on how the immune system which is specifically geared to get rid of non-self-antigens, allows numerous microbes to colonize the human body. In the presence of microbes there are several observations that suggest that there are multiple roles that are played by these microbes in tumor progression and shaping of our immune system which is explained at length in subsequent chapters. Microbial Crosstalk with Immune System: New Insights in Therapeutics discusses the emerging mechanisms of immune-therapeutics as well as its limitations while emphasizing the potential role of microbes in shaping immune-therapeutic and evolving novel strategies to deal with any limitations.
  • Circadian and Visual Neuroscience

    • 1st Edition
    • Volume 273
    • English
    Circadian and Visual Neuroscience, Volume 273 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on topics including Optical set-ups, Psychophysics of Luminance and Color Vision, Psychophysics of non-visual photoreception PRC/IRC/DRC/Spectral Sensitivity, Circadian and visual photometry, Modelling (retina), Modelling (circadian), Techniques for examining vision at the cellular level, Advanced techniques for characterizing the world hyperspectrally, Circadian physiology in mice: Melanopsin, Circadian physiology in mice: Color and cones, Translational aspects of animal studies, Retinal clocks, Primate non-visual physiology, Light and mood in animal models, and much more.
  • Engineered Nanomaterials for Sustainable Agricultural Production, Soil Improvement and Stress Management

    • 1st Edition
    • Azamal Husen
    • English
    Engineered Nanomaterials for Sustainable Agricultural Production, Soil Improvement and Stress Management highlights the latest advances in applying this important technology within agriculture sectors for sustainable growth, production and protection. The book explores various smart engineered nanomaterials which are now being used as an important tool for improving growth and productivity of crops facing abiotic stresses, improving the health of the soil in which those crops are growing, and addressing stresses once the plant begins to produce food yield. The book includes insights into the use of nanoparticles as bactericides, fungicides and nanofertilizers. In addition, the book includes an international representation of authors who have crafted chapters with clarity, reviewing up-to-date literature with lucid illustrations. It will be an important resource for researchers, nanobiotechnologists... agriculturists and horticulturists who need a comprehensive reference guide.
  • Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics

    • 1st Edition
    • Sunny Ohia + 1 more
    • English
    Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics provides a review of the basic anatomy, physiology, biochemistry and pathology of the eye with a focus drug therapy, drug delivery and use of therapeutic medical miniature devices. An understanding of the pharmacological actions of drugs acting on the eye requires the student and health care practitioner to learn additional principles in basic and clinical sciences that are unique to this organ. As a sensory organ, the eye is relatively inaccessible to the systemic circulation due to the blood-vitreous, blood-aqueous and blood-retinal barriers. Consequently, the administration of drugs for therapeutic effects in the eye necessitates an understanding of physico-chemical properties of the molecules and pharmacokinetic principles involved in the access to its site of action via topical, intracameral and intravitreal administration. This book includes information on the general principles of pharmacokinetics and pharmacodynamics of drugs as it pertains to the eye and in combating ocular disorders and diseases. Using a disease-themed approach, the book discusses basic and clinical pharmacological principles involved in the therapy of these diseases including the ocular side effect of systemically-adminis... drugs, drugs used in ophthalmic surgery and miscellaneous agents, the therapeutic utility of biologics, drug conjugates, combination products, gene and cellular therapy are also covered. Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics is useful as a primary and secondary source of reference for up-to-date information about the pharmacological mechanisms of action, pharmacokinetics, side effects, drug-drug interactions and therapeutic indications of drugs for pharmacologists, pharmaceutical scientists, students in the health care disciplines (nursing, pharmacy, optometry, medical), and practitioners in optometry and ophthalmology.
  • Essentials of Medical Biochemistry

    With Clinical Cases
    • 3rd Edition
    • Chung Eun Ha + 1 more
    • English
    Essentials of Medical Biochemistry, Third Edition offers a condensed, yet detailed overview of clinical biochemistry, spanning fundamentals and relevant physiologic and pathophysiologic concepts. Pivotal clinical case studies aid in understanding basic science in the context of diagnosis and treatment of human diseases, and the text illuminates key topics in molecular immunology and hemostasis. Users will find fundamental concepts aiding students and professionals in biochemistry, medicine, and other healthcare disciplines. The text is a useful refresher that will help users meet USMLE and other professional licensing examination requirements, providing thorough introductions, key points, multicolored illustrations of chemical structures and figures, fact-filled tables, and recommended reading lists. This Third Edition has been fully updated to address evolving techniques in the biological sciences, including genomics, metabolomics, transcriptomics, epigenomics, proteomics, and gene therapy, among other methods. In addition, each chapter has been fully revised for current science and now features learning objectives and chapter summaries, supplemental reading, and 5 clinical case based multiple choice questions. New clinical cases have been added throughout.
  • Neurologie de l'adolescence

    • 1st Edition
    • Agathe Roubertie + 1 more
    • French
    L’adolescence est une période unique de transformation de l’individu. Sur le plan somatique, psychique et social, le passage de l’enfance à l’âge adulte est aussi l’occasion de troubles spécifiques ou dont l’expression revêt des aspects particuliers. Ainsi, dans le domaine de la neurologie, cela se traduit par des prévalences plus élevées de certaines affections, ainsi qu’un retentissement singulier sur la personne. Les troubles neurologiques peuvent en effet compromettre les facultés essentielles à l’autonomisation de l’individu, et ont un impact sur l’image que donne l’ado à ses pairs.Sans équivalent, cet ouvrage se justifie donc par les particularités de la prise en charge, les troubles affectant les ados (adolescentes et adolescents) de façon très différente des enfants (qui s’en remettent aux adultes) et des adultes (plus autonomes et responsables dans leur prise en charge).Traitant à la fois des maladies dont les prévalences sont élevées et des affections plus rares, l’ouvrage aborde cette problématique dans toute sa spécificité, en ne négligeant aucune dimension particulière du diagnostic, du traitement et de la prise en charge globale du jeune patient. Chaque chapitre exposera successivement les spécificités à l’adolescence des données épidémiologiques et cliniques (mode de présentation, pièges diagnostiques), puis les principaux diagnostics rencontrés et proposera une prise en charge adaptée à cet âge. La question de la transition des troubles neurologiques de l’enfant à l’âge adulte et de l’accompagnement de l’ado dans sa vie scolaire et sociale sont également abordés.Cet ouvrage s’adresse aux neurologues, pédiatres et neuropédiatres, ainsi qu’aux étudiants déjà entrés dans la spécialité.POINTS CLÉS - Toutes les pathologies touchant les ados, des plus fréquentes aux plus rares - Les spécificités de la prise en charge de l’ado - L’accompagnement de l’ado et la transition vers l’âge adulte
  • Carotenoids: Carotenoid and Apocarotenoid Biosynthesis, Metabolic Engineering and Synthetic Biology

    • 1st Edition
    • Volume 671
    • English
    Carotenoids: Carotenoid and Apocarotenoid Biosynthesis, Metabolic Engineering and Synthetic Biology, Volume 671, the latest release in the Methods of Enzymology series highlights new advances in the field with chapters on Metabolomics-based analysis of carotenoids and related metabolites in various species via quantitative trait loci and genome wide association mapping approaches, Using bacteria for functional analysis of genes encoding carotenoid biosynthetic enzymes, Rice Callus as a High Throughput Platform for Synthetic Biology and Metabolic Engineering of Carotenoids, Transient expression in Nicotiana benthamiana: A simple platform to investigate genes encoding carotenoid biosynthesis enzymes from diverse algal lineages, and much more. Additional chapters in this new release cover Protein-protein interaction techniques to investigate post-translational regulation of carotenogenesis, The isolation of sub-chromoplast structures from tomato and capsicum fruit, Carrot protoplasts as a suitable method for protein subcellular localization, High throughput production and characterization of carotenoid enzymes for structural and functional studies, Production and structural characterization of the cytochrome P450 enzymes in carotene ring hydroxylation, and more.
  • Applications of Nanovesicular Drug Delivery

    • 1st Edition
    • Amit Kumar Nayak + 3 more
    • English
    Applications of Nanovesicular Drug Delivery provides thorough insights and a complete and updated discussion on the preparation, properties and drug delivery applications of various nanovesicles. This volume will discuss target-specific drug application, such as ocular, transdermal, nasal, intravenous and oral delivery. This title is a valuable resource for academics, pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals and regulatory scientists actively involved in pharmaceutical products and process development of tailored-made polysaccharides in drug delivery applications. Recently, there have been a number of outstanding nanosystems in nanovesicular carrier-forms (such as nanoemulsions, self-nanoemulsifying systems, nanoliposomes, nanotransferosomes, etc.), that have been researched and developed for efficient drug delivery by many formulators, researchers and scientists. However, no previously published books have covered all these drug delivery nanovesicles collectively in a single resource.
  • Microbiome, Immunity, Digestive Health and Nutrition

    Epidemiology, Pathophysiology, Prevention and Treatment
    • 1st Edition
    • Debasis Bagchi + 1 more
    • English
    Microbiome, Immunity, Digestive Health and Nutrition: Epidemiology, Pathophysiology, Prevention and Treatment addresses a wide range of topics related to the role of nutrition in achieving and maintaining a healthy gut microbiome. Written by leading experts in the field, the book outlines the various foods, minerals, vitamins, dietary fibers, prebiotics, probiotics, nutritional supplements, phytochemicals and drugs that improve gut health. It specifically addresses molecular and cellular mechanisms and pathways by which these nutritional components contribute to the physiology and functionality of a healthy gut microbiome and gut health. Intended for nutrition researchers and practitioners, food experts, gastroenterologists, nurses, general practitioners, public health officials and health professionals, this book is sure to be a welcomed resource.
  • Plant Exposure to Engineered Nanoparticles

    Uptake, Transformation, Molecular and Physiological Responses
    • 1st Edition
    • Cyren Rico
    • English
    Plant Exposure to Engineered Nanoparticles: Uptake, Transformation, Molecular and Physiological Responses discusses the long-term exposure of plants, including agronomic crops, to nanomaterials in terrestrial environments. Chapters discuss changes in metabolite profiles in plants exposed to engineered nanomaterials, as well as modifications in elemental content of edible portions of plants. Biochemical pathways, root profiles, generational exposure, and biomass productivity are also analyzed in detail. Subsequent chapters cover risks to trophic transfer, as well as human health and ecological functions, before concluding with future approaches to plant-nanomaterial research. The book covers important aspects of the interactions between plant and nanomaterials and will be a valuable resource to scientists and researchers in plant physiology, nanotechnology, agronomy and environmental science.