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    • 8-Membered Heterocycle Synthesis

      • 1st Edition
      • February 21, 2023
      • Navjeet Kaur
      • English
      • Paperback
        9 7 8 0 3 2 3 9 5 6 5 2 9
      • eBook
        9 7 8 0 3 2 3 9 5 6 5 3 6
      8-Membered Heterocycle Synthesis focuses on both the new and established methods for the synthesis of various 8-membered heterocycles. 8-membered heterocyclic compounds act as target molecules for a wide range of synthetic studies and are present in a broad range of natural products, showing a wide variety of pharmaceutical and biological properties. Covering an important and rapidly growing branch of heterocyclic chemistry, this book brings together every protocol for the synthesis of 8-membered heterocycles in one place, allowing the reader to see all the possibilities for making a particular compound using one particular reagent. Providing up-to-date and comprehensive information about the synthesis of medium-ring heterocycles and the latest information on this fast-moving field, with easy access to the synthetic protocols for different 8-membered heterocycles, case studies, and application, this book will be essential reading for students, pharmacologists, biochemists, organic and medicinal chemists, researchers, and academic professionals.

    • Anticandidal Therapeutics

      • 1st Edition
      • January 20, 2023
      • Awanish Kumar + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 8 7 4 4 5
      • eBook
        9 7 8 0 4 4 3 1 8 7 4 5 2
      Developments of antifungal agents have declined as compared to other antibiotics that have displayed a potent development with time. There is an urgent need for both prophylactic and therapeutic treatments worldwide to control the severity of infections caused by Candida. Anticandidal Therapeutics: Discovery and Development provides the readers with a compiled knowledge of the fungal human infection Candida and the development of anticandidal drugs. Anticandidal Therapeutics helps researchers form the basis for the discovery and development of novel anticandidal therapies. In 14 chapters this book provides collective information on anticandidal agents and their discovery and development with respect to major drug transporter families, different stages of anticandidal agent development, recent trends and progress in antifungal translational research, clinical studies status of anticandidal therapeutic agents, and drug repurposing for development of novel anticandidal agents.

    • Degenerative Cervical Myelopathy

      • 1st Edition
      • November 23, 2023
      • Michael G. Fehlings
      • English
      • Hardback
        9 7 8 0 3 2 3 9 5 3 3 4 4
      • eBook
        9 7 8 0 3 2 3 9 5 7 9 1 5
      Degenerative Cervical Myelopathy: From Basic Science to Clinical Practice lays the foundation for understanding DCM manifestation, pathophysiology, diagnosis and treatment strategies. The book covers the latest basic and clinical research, updates on patient management strategies, and discusses promising neuroprotective therapies for the future of DCM care. Written by international experts across a range of topics related to degenerative cervical myelopathy, the book helps readers understand the challenges and future directions of patient management. As degenerative cervical myelopathy (DCM) is the leading cause of spinal cord dysfunction and one of the most common indications for spinal surgery worldwide, the term DCM encompasses a group of chronic, non-traumatic spinal cord injuries that occur due to degenerative changes in the cervical spine (e.g. disc spondylosis or repetitive dynamic injury from hyper-mobility).

    • Recent Developments in Anti-Inflammatory Therapy

      • 1st Edition
      • February 17, 2023
      • Parteek Prasher + 4 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 9 9 8 8 5
      • eBook
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      Advances in Anti-inflammatory Therapy explores the cutting-edge in anti-inflammation therapy in clear and concise language, with insights from academia and industry. Sections cover key regulatory pathways that mediate acute and chronic inflammation and disease onset. Further chapters are devoted to advanced anti-inflammatory pharmaceuticals, including chemical moieties, pharmacophores, APIs, natural products, herbal therapies, molecular nanomedicine and advanced drug delivery vectors. Systematically planned chapters and illustrations enable potential readers to gain essential insights on the most recent advancements in the field. Arranged with systematic chapters covering a broad range of inflammatory diseases, discussions on past, current and future therapeutics and advanced anti-inflammatory pharmaceuticals, this book will be useful to a wide range of researchers, especially medicinal chemists, drug design experts, and biological and translational researchers working in the field of inflammation.

    • The Role of Tropics in Climate Change

      • 1st Edition
      • November 28, 2023
      • Neloy Khare
      • English
      • Paperback
        9 7 8 0 3 2 3 9 9 5 1 9 1
      • eBook
        9 7 8 0 3 2 3 9 9 5 2 0 7
      The Role of Tropics in Climate Change: Global Case Studies uses a 20-chapter, easy-to-understand format to centralize the practical application ideas for functional metagenomics. This important resource not only includes chapters on next-generation sequencing technologies to study important biogeochemical cycles, degradation pathways and detoxification, but also gives insight into several tools that have been developed to integrate metadata and sequence data, allowing downstream comparative analyses of different datasets using several ecological indices. The book further explains newly developed techniques for sequencing DNA, generating shorter fragments than Sanger sequencing techniques to quickly read larger sequences in a shorter amount of time.

    • The Thinking Healthcare System

      • 1st Edition
      • February 17, 2023
      • Dominique J. Monlezun
      • English
      • Paperback
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      • eBook
        9 7 8 0 4 4 3 1 8 9 0 7 4
      The Thinking Healthcare System: Artificial Intelligence and Human Equity is the first comprehensive book detailing the historical, global, and technical trends shaping the evolution of the modern healthcare system into its final form—an AI-driven thinking healthcare system, structured and functioning as a global digital health ecosystem. Written by the world’s first triple doctorate trained physician-data scientist and ethicist, and author of three AI textbooks and over 350 scientific and ethics papers, this indispensable resource makes sense of how technology, economics, and ethics are already producing the future’s health system—and how to ensure it works for every patient, community, and culture in our globalized, digitalized, and divided world. Providing clear descriptions and concrete examples, this book brings together AI-accelerated digital health ecosystems, data architecture, cloud and edge computing, precision medicine, public health, telemedicine, patient safety, health political economics, multicultural global ethics, blockchain, and quantum health computing, among other topics. Healthcare and business executives, clinicians, researchers, government leaders, policymakers, and students in the fields of healthcare management, data science, medicine, public health, informatics, health and public policy, political economics, and bioethics will find this book to be a groundbreaking resource on how to create, nourish, and lead AI-driven health systems for the future that can think, adapt, and so care in a manner worthy of the world’s patients.

    • Adolescent Psychosis

      • 1st Edition
      • February 8, 2023
      • Ingrid Agartz + 1 more
      • English
      • Paperback
        9 7 8 0 3 2 3 8 9 8 3 2 4
      • eBook
        9 7 8 0 3 2 3 8 9 8 7 7 5
      Adolescent Psychosis: Clinical and Scientific Perspectives presents new methodologies and novel scientific findings, with a comprehensive orientation into the genetics, phenomenology, nosology, and long-term outcome of adolescent early-onset psychosis research. This volume discusses recent epidemiological studies, along with co-morbid aspects associated with other neurodevelopmental syndromes and somatic diseases. The book also provides suggestions for future research using a translational perspective, from genes to the clinic to and relevant phenotypes, biomarkers, treatment options and etiological aspects. Topics discussed bring together expert researchers in the field to represent different perspectives and future possibilities.

    • Alzheimer's Disease and Advanced Drug Delivery Strategies

      • 1st Edition
      • November 30, 2023
      • Bhupendra G. Prajapati + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 3 2 0 5 6
      • eBook
        9 7 8 0 4 4 3 1 3 2 0 6 3
      Alzheimer's Disease and Advanced Drug Delivery Strategies compiles under a single volume the most recent advances in drug delivery to the brain as related to AD treatment. The book's editors recruited scientists from around the world to produce high quality chapters covering not only nanotechnological approaches, but also microsphere, niosomes, and liposomes. Among the topics covered are synthetic molecules, nobiletin, nose to brain delivery, natural biomaterials, cationic nanoformulations, dendrimers, microbubbles, and more. This book represents a complete reference for academic and corporate pharma researchers investigating targeted drug delivery to the brain.

    • Medicinal Usage of Cannabis and Cannabinoids

      • 1st Edition
      • June 2, 2023
      • Victor R Preedy + 2 more
      • English
      • Hardback
        9 7 8 0 3 2 3 9 0 0 3 6 2
      • eBook
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      There is a growing body of data supporting the usage of cannabis and cannabis-related products in alleviating or preventing symptoms in different diseases and conditions. Medicinal Usage of Cannabis and Cannabinoids offers readers a comprehensive reference on the medical usage and symptom relief provided by these compounds in a variety of disorders. With coverage of neurological diseases like Alzheimer’s and Parkinson’s, and a wide range of other afflictions including depression, anxiety, nausea, and cancer, this broad coverage allows readers to learn about symptom control but also physiological, psychological, and pharmacological effects of these compounds. Unique case reports are provided as well. This volume provides a platform for research on the use of these compounds in improving patient care, brain function, and neurological dysfunction.

    • Ketogenic

      • 1st Edition
      • June 22, 2023
      • Tim Noakes + 6 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 6 1 7 0
      • eBook
        9 7 8 0 1 2 8 2 1 6 2 3 1
      **Selected for Doody’s Core Titles® 2024 in Nutrition**Ketogenic... The Science of Therapeutic Carbohydrate Restriction in Human Health presents the most up-to-date and evidence-based science and research available in the field of TCR, with the purpose of training medical and allied healthcare professionals on the effective therapeutic use of low-carbohydrate and ketogenic nutrition in clinical practice. This book explores the appropriate, safe, and effective use of TCR to improve patient outcomes in a broad range of chronic metabolic conditions and aims to promote health.Focused on lifestyle management, health support and the treatment of diseases rooted in poor nutrition, this book explores the role of food and lifestyle modification as medicine and is a valuable resource for nutritionists, dietitians and medical professionals who provide diet-related counselling, as well as those researching or studying related areas.

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