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Books in Life sciences

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2101-2110 of 14737 results in All results

Modeling Electrochemical Dynamics and Signaling Mechanisms in Excitable Cells with Pathological Case Studies

  • 1st Edition
  • January 18, 2022
  • Tetsuya Watanabe
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 8 8 0 3 - 2
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 7 2 7 0 - 3
Modeling Electrochemical Dynamics and Signaling Mechanisms in Excitable Cells with Pathological Case Studies covers the neuronal cell communication system in excitable cells, recognizing the most relevant mechanisms of cell communication. Along with new findings in biotechnology, medicine and pathological cases for clinicians, the book highlights electrochemical potential in  living nerve and muscle cells. Written for physiological scientists, pharmaceutical scientists, medical doctors, biologists and physicists, this book an essential read for a real understanding of the signals as we see them.

Current Topics in iPSCs Technology

  • 1st Edition
  • Volume 17
  • January 18, 2022
  • Alexander Birbrair
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 9 8 9 2 - 5
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 8 3 9 8 - 3
Current Topics in iPSCs provides a deep analysis of the underlying fundamentals that support short and mid-term developments and milestones in the business of mesenchymal stem cell therapies. This volume explores the next frontier of MSC therapies and how the transformational potential of therapeutic adult cells will be realised in all therapy areas. The impacts of clinical and economic benefits are dissected throughout each of the chapters. Written by thought leaders in the field for those curious about the interface of science and business.

Biomarkers in Bipolar Disorders

  • 1st Edition
  • January 16, 2022
  • Rodrigo Machado-Vieira + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 1 3 9 8 - 8
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 1 3 9 9 - 5
Biomarkers in Bipolar Disorders summarizes cutting-edge findings in biomarkers' research, emphasizing the most promising findings, tools and technologies relevant to drug development and personalized medicine. Key findings cover different levels of evidence such as genes, molecules, cells, systems, brain and behavior related to diagnosis (state and trait/endophenotypes), prediction of treatment response and follow-up outcomes, along with the most promising perspectives in each area. Each section includes a comprehensive and focused overview on the state-of-the-art and perspectives. The book concludes with a section on practical applications, encompassing diagnostics development (genetic testing, biomarkers), and new drug development. Edited by Dr. Rodrigo Machado-Vieira and Dr. Jair C. Soares, and contributed by leading experts in the field of biomarker research, this book will be become the leading tool for all researchers and clinicians in Bipolar Disorder.

Chronic Obstructive Pulmonary Disease (COPD) Diagnosis using Electromyography (EMG)

  • 1st Edition
  • January 16, 2022
  • Archana Bajirao Kanwade + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 0 0 5 0 - 8
  • eBook
    9 7 8 - 0 - 3 2 3 - 8 8 6 0 8 - 6
Chronic Obstructive Pulmonary Disease (COPD) Diagnosis using Electromyography (EMG) presents a new and innovative method of COPD diagnosis using EMG to analyze sternomastoid muscle activity using features extraction and classification. The book describes the methodology of EMG analysis, the slope-based onset detection algorithm and SEMG analysis in time, frequency and time frequency domain analyses. It also explores the identification of frequencies for single frequency Continuous Wavelet Transform (CWT) analysis and feature extraction and selection for successful classification COPD into its severity grades. The book provides a compilation of all techniques used in the literatures and emphasizes newly proposed techniques for the early detection of COPD. Fully comprehensive, the book includes discussion of limitations of existing methods for COPD diagnosis and introduces new efficient methods for COPD identification, classification and early diagnosis.

Neuroplasticity

  • 1st Edition
  • Volume 184
  • January 14, 2022
  • Angelo Quartarone + 2 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 1 9 4 1 0 - 2
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 9 4 1 1 - 9
Neuroplasticity: From Bench to Bedside, Volume 184 in the Handbook of Clinical Neurology series, provides a comprehensive multidisciplinary guide to neuroplasticity. Sections summarize the basic mechanisms of neuroplasticity, focus on neuroplasticity in movement disorders, discuss brain oscillations in neurological disorders, segue into plasticity in neurorehabilitation, and cover issues of inflammation and autoimmunity in neuroplasticity. The book concludes with a section on neuroplasticity and psychiatric disorders.

Formulation and Device Lifecycle Management of Biotherapeutics

  • 1st Edition
  • January 14, 2022
  • Beate Bittner + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 3 7 4 1 - 0
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 3 7 4 2 - 7
Today, the pressure on healthcare costs and resources is increasing, and especially for biopharmaceuticals that require parenteral administration, the inherent complex and invasive dosing procedure adds to the demand for efficient medical management. In light of the COVID-19 pandemic the value of drug delivery technologies in enabling a flexible care setting is broadly recognized. In such a setting, patients and their caregivers can choose the place of drug administration based on individual preferences and capabilities. This includes not only dosing in the clinic but also supervised at-home dosing and self-administration for eligible patients. Formulation and Device Lifecycle Management of Biotherapeutics: A Guidance for Researchers and Drug Developers covers the various aspects of improving drug delivery of biological medicines with the ultimate goal to reduce dosing complexity associated with parenteral administration and, thus, enhance patient experience and drug administration-related healthcare capacity. The target audience are multidisciplinary researchers and drug developers in the pharmaceutical industry, biotech companies, and academia involved in formulation and device development. This includes pharmacology and medical experts in charge of generating nonclinical and clinical data to support approval of novel dosing regimens, and drug delivery scientists and engineers responsible for technical particulars of product optimizations. Moreover, professionals in market access and commercial functions are expected to benefit from the discussions about the impact of patient and healthcare provider needs and country-specific reimbursement models on realizing a truly convenient and cost and resource efficient drug delivery solution.

Antiangiogenic Drugs as Chemosensitizers in Cancer Therapy

  • 1st Edition
  • Volume 18
  • January 14, 2022
  • Lucia Morbidelli
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 9 0 1 9 0 - 1
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 0 5 5 6 - 5
Anti-angiogenic Drugs as Chemosensitizers in Cancer Therapy, Volume 19 focuses on the use of anti-angiogenic drugs as sensitizers of tumor cells to the inhibitory activity of antitumor agents. Conventional and novel anti-neoplastic agents (cytotoxic molecules, hormones/antihormones, immunotherapies) are taken into consideration, along with advances made in combination therapies. The book encompasses examples of studies on the use of antiangiogenic compounds—molecules that inhibit the growth of vessels inside a tumor—together with antineoplastic drugs in order to sensitize the resistant tumor to their cytotoxic effects, thus reducing adverse side reactions and resistance and improving the therapeutic response of cancer patients. In addition, the book discusses clinical applications in various types of cancer, such as colorectal, lung, breast, renal, genitourinary, skin and brain and circulating tumors. It is a valuable resource for cancer researchers, clinicians and members of the biomedical field who wants to be up-to-date on the most recent and promising developments in the field.

Advances in Protein Molecular and Structural Biology Methods

  • 1st Edition
  • January 14, 2022
  • Timir Tripathi + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 0 2 6 4 - 9
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 0 2 6 5 - 6
Advances in Protein Molecular and Structural Biology Methods offers a complete overview of the latest tools and methods applicable to the study of proteins at the molecular and structural level. The book begins with sections exploring tools to optimize recombinant protein expression and biophysical techniques such as fluorescence spectroscopy, NMR, mass spectrometry, cryo-electron microscopy, and X-ray crystallography. It then moves towards computational approaches, considering structural bioinformatics, molecular dynamics simulations, and deep machine learning technologies. The book also covers methods applied to intrinsically disordered proteins (IDPs)followed by chapters on protein interaction networks, protein function, and protein design and engineering. It provides researchers with an extensive toolkit of methods and techniques to draw from when conducting their own experimental work, taking them from foundational concepts to practical application.

Hormones

  • 4th Edition
  • January 13, 2022
  • Gerald Litwack
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 9 0 2 6 2 - 5
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 8 4 6 0 - 7
Hormones, Fourth Edition provides a report on the field of human hormones viewed in light of our current understanding of cellular and subcellular architecture, along with the molecular details of their modes of action. Comprehensive information about hormone action on canonical and non-canonical signaling pathways at cellular and subcellular level and effects on architecture and function of organ systems are discussed. All chapters in this new edition have been completely updated to cover advances in endocrinology research, which has expanded significantly in the last few years. Vast coverage of hormones not previously covered and newly discovered aspects of hormone action are also included. This new fourth edition is intended to be used by advanced undergraduates and graduate students in the biological sciences. It will also provide useful background information for health professionals, clinicians and researchers in the field of endocrinology, metabolism and biochemistry.

Advances in Agronomy

  • 1st Edition
  • Volume 171
  • January 13, 2022
  • Donald L. Sparks
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 9 8 8 4 1 - 4
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 8 8 4 2 - 1
Advances in Agronomy, Volume 171, the latest release in this leading reference, contains a variety of updates and new advances in the field, including updates on Elevated CO2 in Semi-arid Cropping Systems: A Synthesis of Research from the Australian Grains Free Air CO2 Enrichment (AGFACE) Research Program, Simultaneous Effects of Legume Cultivation on Carbon and Nitrogen Accumulation in Soil, Growing Small Grains Organically in the Semiarid West: A Review of Markets and Management Practices to Optimize Productivity and Sustainability, Principles and Applications of Topography in Precision Agriculture, Retention of Heavy Metals by Dredged Sediments and their Management Following Land Application, and more. Other chapters focus on Genetic Diversity for Developing Climate-resilient Wheats to Achieve Food Security Goals and A Century of Subclover: Lessons for Sustainable Intensification from a Historical Review of Innovations in Subterranean Clover Seed Production.

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