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Elsevier

Books in Life sciences

  • Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics

    • 1st Edition
    • Lara Scheherazade Milane + 1 more
    • English
    Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics delves into the complex world of intercellular communication biology and its implications on therapeutics. This book covers all areas of intercellular communication and therapeutics in development for different forms of communication, including their role in diseases such as cancer, neurological disorders, metabolic diseases, and inflammatory/immune diseases. Sections provide an introduction, biological targets, challenges, and approaches to overcoming biological barriers and the significance of contact points and mechanisms of internalization. Specifics of tunneling nanotubes, extracellular vesicles, and the immune and non-immune interface in various diseases are covered. Furthermore, the book explores the crosstalk of different forms of intercellular communication and the implications of mitochondrial exchange in the four primary pathological areas. This is an essential resource for researchers, students, and professionals in the field of drug development and delivery. By connecting the dots between extracellular vesicles, tunneling nanotubes, and cell-cell junctions, this book serves as a foundation for further advancements in the science of intercellular communication and it's applications to new drug discovery and delivery.

  • Molecular Tools and Infectious Disease Epidemiology

    • 2nd Edition
    • Betsy Foxman + 1 more
    • English
    Molecular Tools and Infectious Disease Epidemiology, Second Edition examines the opportunities and methodologic challenges in the application of modern molecular genetic and biologic techniques to infectious disease epidemiology. The application of these techniques dramatically improves the measurement of disease and putative risk factors, increasing our ability to detect and track outbreaks, identify risk factors and detect new infectious agents. However, integration of these techniques into epidemiologic studies also poses new challenges in the design, conduct, and analysis. This book presents the key points of consideration when integrating molecular biology and epidemiology; discusses how using molecular tools in epidemiologic research affects program design and conduct; considers the ethical concerns that arise in molecular epidemiologic studies; and provides a context for understanding and interpreting scientific literature as a foundation for subsequent practical experience in the laboratory and in the field. The book is recommended for graduate and advanced undergraduate students studying infectious disease epidemiology and molecular epidemiology; and for the epidemiologist wishing to integrate molecular techniques into their studies.

  • Membrane Transporters and Drug Delivery

    A Comprehensive and Multidisciplinary Guide
    • 1st Edition
    • Elena Puris + 3 more
    • English
    Membrane Transporters and Drug Delivery: A Comprehensive and Multidisciplinary Guide is a comprehensive reference on the rapidly evolving field of membrane transporters and their role in drug delivery. The book begins with a comprehensive introduction to membrane transporters and their function, structure, and regulation mechanisms. It then moves into the impact of diseases on transporters and how this may affect pharmacokinetics. The book also presents the latest advancements in transporter-mediated drug delivery, examines the roles of both efflux and influx transporters in drug pharmacokinetics, and covers different strategies for utilizing membrane transporters for drug delivery and targeting specific tissues and cell types.It concludes with a discussion on the regulatory and industrial aspects of transporter-related projects, explores the potential of artificial intelligence in transporter and drug delivery research, and offers a glimpse into future challenges and perspectives in this field.

  • Pulse Breeding, Processing, Functionality, and Products

    • 1st Edition
    • Fatma Boukid + 3 more
    • English
    Pulse Breeding, Processing, Functionality, and Products reflects the shift from animal- to plant-based foods, addressing increased interest in pulses due to their higher protein contents when compared to most cereals. The book provides comprehensive coverage of a wide range of knowledge related to pulses, from breeding approaches and market landscapes to extraction and fractionization, post- treatments for improved ingredients, their nutritional and compositional qualities, advances in testing methods, and their potential industrial applications in food and pet food. With its inclusion of problems/solutions and issues-focused insights, the book's content is valuable for immediate application and for inspiring additional research. The book offers the food industry and researchers the necessary insights to know the latest developments and emerging uses of pulse ingredients. As pulses have high adaptability, versatility, and offer potentially significant contributions to the human diet and pulse ingredient flours, proteins, fibers, and starches, they are increasingly being used in food formulations, hence this book covers the topic with a wide breadth of knowledge. Challenges, including taste, color, bite, mouthfeel, and texture are also covered for innovative products.

  • Toxicology Disasters

    Causes and Consequences
    • 1st Edition
    • Sue Ford
    • English
    Toxicology Disasters: Cause and Consequences, a volume in the History of Toxicology and Environmental Health series, provides an historical overview of significant toxicological disasters which involved chemical exposure of humans, animals or the environment. The book documents the timeline of events and the legacy of the resulting exposure which occurred within a specific period of time, but with long lasting consequences. Case studies of toxicological incidents and a wide range of categories, including environmental, industrial, pharmaceutical, domestic and international are not only discussed from a historical perspective but also regarding their impacted toxicology, regulation and our current use of these chemicals.The book will help toxicologists, academics and students from environmental health and toxicology departments, environmental/occupa... health regulators, and industrial hygiene/safety personnel gain a better understanding of the arc of a toxicological disaster from its origins, root causes of the problem, and initial and long-term assessments and management.

  • Endovascology

    Endovascular Treatment of Vascular Systematic Pathologies
    • 1st Edition
    • Zaiping Jing + 2 more
    • English
    Vascular diseases have high incidence, disability and mortality rates. Endovascular treatment is an important option as an alternative to open surgery, with the proven ability to counter severe pathologies. China-based research into vascular diseases and endovascular surgery has been proceeding apace. Endovascology presents, for the first time, the latest research, clinical outcomes, and research frontiers from one of the leading institutes in China specializing in endovascular surgery — the Vascular Surgery Department of Changhai Hospital. Specifically, in this book, chapters cover each aspect of vascular disease: Vascular heart disease; Congenital heart disease; Arteriosclerotic heart disease; Thoracic aortic pathology; Thoracoabdominal aortic pathology; Infrarenal abdominal aortic pathology; Cerebral perfusion arteries; Upper limb vessels; Abdominal visceral arteries; Iliac artery; Lower limb artery; Varicose veins; Deep venous thrombosis of the lower limb; Pelvic congestion syndrome; Inferior vena cava and portal vein; Pulmonary artery; and Lymphatic diseases. Endovascology: Endovascular Treatment of Vascular Systematic Pathologies presents a global medical audience with an ambitious, systematic and exhaustive review of vascular diseases, and the state-of-the art in clinical research and practice in endovascology. It will be of use to surgeons, trainees in minimally invasive cardiovascular techniques, vascular disease researchers, and medical students alike.

  • Wood-Water Interactions

    • 1st Edition
    • Samuel L. Zelinka + 3 more
    • English
    Wood-Water Interactions examines wood-water interactions in an intuitive approach to such a highly interdisciplinary topic. While wood-moisture interactions dominate nearly every facet of wood technology and wood use, many wood scientists have only a rudimentary understanding of these interactions as previous books on this topic are opaque and esoteric. Authored by experts in the field, the chapters follow a logical structure as well as case studies and vivid illustrations; the reader is motivated to understand updated information about the interaction of moisture with wood, the effect of changes in water status on the properties of wood raw material, and changes in the mechanical properties of wood during drying and humidification.

  • Animal Stress Biology

    Applications across Natural and Man-made Systems
    • 1st Edition
    • Edward Narayan
    • English
    Animal Stress Biology: Applications across Natural and Man-made Systems provides the fundamental aspects of stress endocrinology with a major focus on the applications of stress research in animal welfare. Early sections introduce the basics of animal stress biology in major taxa. Latter sections explore how animal stress varies across species and settings and how this research can be applied to improve animal welfare. The book incorporates chapter summaries, key term definitions, global case studies, and discussion sections throughout, making it an indispensable resource to students and early career professionals, as well as specialists in agriculture, zoos, clinical research settings, and resource management.Stress plays an integral part in the maintenance of homeostasis in animals and is a useful measure of animal responses to management interventions across natural, agricultural, and clinical settings. Written by experts in the field of animal stress biology, this book is systematically structured for easy student navigation.

  • Bioprospecting Native Microbiomes for Boosting Phytoremediation

    • 1st Edition
    • Vimal Chandra Pandey + 1 more
    • English
    Bioprospecting Native Microbiomes for Boosting Phytoremediation provides an inclusive overview of the use of metal-resistant native microbiomes for boosting the phytoremediation of polluted land for ecological and environmental restoration. The book offers a basic understanding of the principles and mechanisms of microbe-induced phytoremediation, microbiome resilience, adaptation to polluted lands, and metal-resistant native microbe-assisted phytotechnologies. It covers current trends, tools, and policies for the microbe-augmented remediation of an array of metals and metalloids. Other sections discuss key topics such as plant-metal-microbe interaction in polluted ecosystems, microbe-mediated phytoremediation for upgraded ecosystem services, and success stories on microbial-assisted phytoremediation.

  • Postharvest Loss and Waste Management of Horticultural Produce

    From Farm to Fork
    • 1st Edition
    • Zahra H. Mohammad + 2 more
    • English
    Postharvest Loss and Waste Management of Horticultural Produce: From Farm to Fork addresses the major challenges and root causes of postharvest losses while also presenting solutions to reduce losses using innovative technologies. Sections introduce an overview of postharvest challenges, such as postharvest handling, storage, and transportation of fruits, vegetables, and berries, along with the impact of COVID-19 on postharvest losses. Other sections cover postharvest biological issues and control, such as postharvest diseases and microbiology issues of produce, novel technologies for reducing postharvest loss and waste in horticulture, like biological control, packaging, MAP films, etc., and mitigation strategies. A final section explores the environmental, economic, and social impact of postharvest losses across the food supply chain. Edited by a team of experts in the field, this is an excellent resource that brings sustainable solutions to reduce postharvest losses on a global level. Attracting a wider audience in the fields of food engineering and technology, as well as professionals, researchers, and academicians working in the fields of postharvest losses and their management, this book will be a welcomed resource.

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