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Books in Pharmacology

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Environmental Carcinogenesis

  • 1st Edition
  • Volume 96
  • Max Costa
  • Max Costa
  • February 24, 2023
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 9 9 7 7 5 - 1
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 9 7 7 6 - 8
Environmental Carcinogenesis, Volume 96 in the Advances in Pharmacology series, reports on work done with carcinogenic metals and the mechanisms of their carcinogenicity, including Arsenic and Chromate. Chapters in this release include Breast cancer carcinogenesis by organophosphate pesticides, Polyadenylation of Canonical histone H3.1 in Carcinogenesis, Epigenomic reprogramming in iAs-mediated carcinogenesis, MicroRNAs and epigenetic regulation in metal-induced angiogenesis and carcinogenesis, Environmental epigenetics and new mechanistic markers of chemical exposure, Arsenic carcinogenesis by inhibition of DNA repair, Genetic and environmental reprogramming of the sarcoma epigenome, Mechanism of chromate carcinogenesis by chromatin alterations, and more. Other chapters cover Arsenic carcinogenesis and microRNAs, Epigenetic mechanism of Cr(VI)-induced cell malignant transformation and tumorigenesis, The dark side of NRF2 in arsenic carcinogenesis, and Chemical mechanisms of DNA damage by carcinogenic chromium(VI).
Environmental Carcinogenesis

Standardizing Pharmacology: Assays and Hormones

  • 2nd Edition
  • Michael J. Parnham, Clive Page + 1 more
  • Michael J. Parnham, Clive Page and Jacques Bruinvels
  • February 23, 2023
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 8 5 5 1 7 - 4
  • eBook
    9 7 8 - 0 - 3 2 3 - 8 5 5 1 8 - 1
Standardizing Pharmacology: Assays and Hormones, Volume Two in the Discoveries in Pharmacology series, presents selected articles from historic discoveries that are enhanced with commentary from contemporary scholars who present discussions on the importance of each chapter, along with an updated bibliography on the subject and contributions from a Nobel Prize winner and other pioneers in pharmacology. Academic and industry researchers in pharmacology and medicine, as well as advanced students will find this series a useful teaching tool and launch to new discoveries. Sections cover key discoveries in receptor theory, pharmacological methods and the development of hormone therapy, including J. Parascandola on the development of receptor theory, R.S. Yalow on radioimmunoassay, M. van Rossum and J.T L.A. Hurkmans on bioassays, M. Tausk on androgen therapy and C. Djerassi on oral contraceptives, with commentaries from experts such as T. Hökfelt and V.C. Jordan.
Standardizing Pharmacology: Assays and Hormones

Lantibiotics as Alternative Therapeutics

  • 1st Edition
  • Sanket Joshi, Rajiv K. Kar + 2 more
  • Sanket Joshi, Rajiv K. Kar, Dibyajit Lahiri + 1 more
  • February 17, 2023
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 9 1 4 1 - 4
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 9 1 4 2 - 1
Lantibiotics as Alternative Therapeutics explores alternative therapeutics, lantibiotics and other novel drugs. This book provides concrete information to readers regarding lantibiotics and various types of antimicrobial peptides with their mode of actions in treating various multidrug resistant organisms. It explains various techniques that are involved in analyzing antimicrobial peptides and their mode of actions. The development of antibiotic resistance has now reached a point of crisis where innovative methods and application of novel compounds and methods are required to prevent the spread of drug resistant infections. Novel compounds exhibit different modes of action to the currently used mechanism of therapeutics in order to combat against the resistant organisms. Lantibiotics hold considerable potential as a consequence of their unusual structure, unique mechanisms of action and their potency against multi-drug resistant bacteria. This book will be useful for pharmaceutical industry scientists and researchers in microbial and biomedical research as well as graduate and advanced students in microbiology, medical biotechnology, health, and pharmaceutical sciences.
Lantibiotics as Alternative Therapeutics

Recent Developments in Anti-Inflammatory Therapy

  • 1st Edition
  • Parteek Prasher, Flavia Zacconi + 3 more
  • Parteek Prasher, Flavia Zacconi, Kamal Dua + 2 more
  • February 17, 2023
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 9 9 8 8 - 5
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 1 4 1 6 - 1
Advances in Anti-inflammatory Therapy explores the cutting-edge in anti-inflammation therapy in clear and concise language, with insights from academia and industry. Sections cover key regulatory pathways that mediate acute and chronic inflammation and disease onset. Further chapters are devoted to advanced anti-inflammatory pharmaceuticals, including chemical moieties, pharmacophores, APIs, natural products, herbal therapies, molecular nanomedicine and advanced drug delivery vectors. Systematically planned chapters and illustrations enable potential readers to gain essential insights on the most recent advancements in the field. Arranged with systematic chapters covering a broad range of inflammatory diseases, discussions on past, current and future therapeutics and advanced anti-inflammatory pharmaceuticals, this book will be useful to a wide range of researchers, especially medicinal chemists, drug design experts, and biological and translational researchers working in the field of inflammation.
Recent Developments in Anti-Inflammatory Therapy

Laboratory Animal Anaesthesia and Analgesia

  • 5th Edition
  • Paul Flecknell
  • Paul Flecknell
  • February 8, 2023
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 8 2 6 8 - 0
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 8 2 6 9 - 7
Laboratory Animal Anaesthesia and Analgesia, Fifth Edition provides a basic guide to anesthesia for a very diverse audience involved in animal testing. This has been the go-to resource for current, clear and evidence-based information for over 30 years. The book is divided into four parts that deal with preparation for anesthesia, including definitions, equipment, preparations, anesthetic and analgesic agents, the management and monitoring of anesthesia, including pre-procedural preparations, monitoring and problems and emergencies through the procedure, advanced and specialized techniques, and analgesia and post-operative care, including recovery and the prevention and management of post-operative pain. Final sections cover anesthesia in common laboratory species, specifically: rodents, rabbits, cats, dogs, ferrets, pigs, sheep and goats, primates, reptiles, amphibians and new specific chapters on birds, fish and cephalopods. This edition keeps up with the tradition of bringing a balanced dose of practical advice, foundational content, and current, updated references, drugs and procedures to veterinarians, technicians, researchers and ethics committee personnel.
Laboratory Animal Anaesthesia and Analgesia

Anti-Aging Pharmacology

  • 1st Edition
  • Vitaly Koltover
  • Vitaly Koltover
  • December 7, 2022
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 3 6 7 9 - 6
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 3 6 8 0 - 2
Anti-Aging Pharmacology provides an overview of current research aimed at the pharmacological modulation of aging, including a discussion of the growing number of novel drug classes with promising anti-aging potential. The aging process is the main risk factor for all chronic diseases affecting the elderly. With lifespans extending across the globe, these chronic diseases are placing a larger burden on individuals and health care systems. Therefore, slowing down the aging rate could be more effective in delaying aging-associated chronic disorders than combating them one by one, which is the conventional approach in a current disease-based pharmacological paradigm. This book contains the work of the world’s leading researchers in the field, including sections on the conceptual and methodological background of anti-aging pharmacology, the basic classes of anti-aging drugs, phytochemicals, outcomes of anti-aging developments and future directions. This book will be of interest to a wide audience, ranging from pharmacologists, medicinal chemists and academic researchers in gerontology, biomedical sciences and those in medical practice.
Anti-Aging Pharmacology

Elemene Antitumor Drugs

  • 1st Edition
  • Tian Xie
  • Tian Xie
  • December 2, 2022
  • English
  • Hardback
    9 7 8 - 0 - 4 4 3 - 2 1 4 4 3 - 1
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 3 2 4 8 - 3
Elemene Antitumor Drugs: Molecular Compatibility Theory and its Applications in New Drug Development and Clinical Practice introduces natural anti-tumor drug elemene and systematic basic and clinical research. Basic principles of the compatibility theory of traditional Chinese medicine and the research and development process of the natural anti-tumor drug elemene under the guidance of this principle are introduced. In addition, the traditional extraction and separation of elemene and the new biosynthesis technology developed by the author's team are described. Then, the systematic anti-tumor mechanism research of elemene are introduced, including unique multi-target and comprehensive anti-tumor mechanisms and detailed mechanisms for treating specific tumors. Under the guidance of compatibility theory, clinical research on the combined application of elemene and different chemotherapeutic drugs has been further carried out, achieving positive results in clinical practice. Finally, the book also introduces the research and exploration of new drug delivery systems of elemene, as well as the structural modification and drug discovery progress taking elemene structure as the lead compound.
Elemene Antitumor Drugs

Advances in Extraction and Applications of Bioactive Phytochemicals

  • 1st Edition
  • Mihir Kumar Purkait, Dibyajyoti Haldar + 1 more
  • Mihir Kumar Purkait, Dibyajyoti Haldar and Prangan Duarah
  • November 30, 2022
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 8 5 3 5 - 9
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 8 5 3 6 - 6
Advances in Extraction and Applications of Bioactive Phytochemicals presents comprehensive and systematic coverage of extraction techniques for bioactive phytochemical compounds and their delivery and therapeutic effectiveness. Sections focus on the pharmaceutical industry’s perspective, aiming at compiling recent advances of natural products in the field of drug delivery, including a brief overview of plant-based bioactive molecules, utilization of different plant elements for the extraction of phytochemicals, a compilation of conventional extraction approaches, advanced extraction methods, including Supercritical carbon-dioxide extraction, computational methods to improve production, drug delivery aspects of bioactive phytochemicals, their therapeutic effectiveness, and more. This book is a complete reference targeted at pharma researchers in academic and corporate environments and those willing to apply the most current extraction methods and health applications. Researchers in medicinal chemistry and chemical engineering will also benefit from this comprehensive resource.
Advances in Extraction and Applications of Bioactive Phytochemicals

The South African Herbal Pharmacopoeia

  • 1st Edition
  • Alvaro Viljoen, Maxleene Sandasi + 3 more
  • Alvaro Viljoen, Maxleene Sandasi, Gerda Fouche + 2 more
  • November 23, 2022
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 9 9 7 9 4 - 2
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 9 7 9 5 - 9
The South African Herbal Pharmacopeia: Monographs of Medicinal and Aromatic Plants is a collection of 25 original monographs of medicinal plants that are currently under commercialization or have the potential for commercialization into herbal medicinal products for the global marketplace. Chapters include a general overview covering synonyms, common names, conservation status, botany, geographical distribution, ethnopharmacology, commercialization, pharmacological evaluation, chemical profiling and quality control, including HPTLC fingerprint analysis, UPLC analysis, gas chromatography and mid-infrared spectroscopy analysis. Academics researching pharmacy and analytical chemistry will benefit from the detailed chemical profile on each species presented. Industrial manufacturers of herbal products, herbal medicines, cosmetics, food supplements, and national and international policymakers and regulators will benefit from the overview provided at the beginning of each chapter.
The South African Herbal Pharmacopoeia

Virtual Screening and Drug Docking

  • 1st Edition
  • Volume 59
  • Julio Caballero
  • Julio Caballero
  • November 17, 2022
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 9 8 5 9 5 - 6
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 8 6 0 5 - 2
Virtual Screening and Drug Docking, Volume 59 in the Annual Reports on Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Can docking scoring functions guarantee success in virtual screening?, No dance, no partner! A tale of flexibility in docking and virtual screening, Handling Imbalance Data in Virtual Screening, Rational computational approaches to predict novel drug candidates against leishmaniasis, Virtual screening against Mtb DNA gyrase: Applications and success stories, Using Filters in Virtual Screening: A Brief Guide to Minimize Errors and Maximize Efficiency, and more. Additional chapters in the new release include Machine Learning and Deep Learning Strategies for Virtual Screening, Applications of the Virtual Screening to find the novel HIV-1 therapeutic agents, and Large-scale screening of small molecules with docking strategies and its impact on drug discovery.
Virtual Screening and Drug Docking