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Books in Pharmaceutical science general

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    • Biomarkers, Diagnostics and Precision Medicine in the Drug Industry

      • 1st Edition
      • June 8, 2019
      • Abdel Halim
      • English
      • Paperback
        9 7 8 0 1 2 8 1 6 1 2 1 0
      • eBook
        9 7 8 0 1 2 8 1 6 1 2 2 7
      The high failure rate in the pharmaceutical industry has positioned biomarkers and personalized medicine in the frontline, as possible solutions. If executed right, biomarkers and companion diagnostics (CDx) can potentially help the drug industry enhance the probability of success, accelerate the time to market, and, more importantly, benefit patients by supporting accurate diagnosis and selection of the most effective and least toxic therapies. This book aims to examine the challenges and limitations in biomarkers and laboratory tests. It also offers advice on best practices to ensure proper application of biomarkers and bridges the gap between diagnostic business development claims and real-life deliverables. The book covers biomarkers for different purposes, provides examples from different technologies, which includes standard-of-care approved assays as well as for-investigational-... and for-research-use-onl... assays. It also includes new data for biomarkers in different therapeutic indications and offers case studies and practical examples. This book serves as a reference to drug developers, IVD providers, clinical labs, healthcare givers, academicians, and researchers for best practices to help increase the probability of success in drug development and improve patient management.

    • NETosis

      • 1st Edition
      • June 1, 2019
      • Geeta Rai
      • English
      • Paperback
        9 7 8 0 1 2 8 1 6 1 4 7 0
      • eBook
        9 7 8 0 1 2 8 1 6 3 7 9 5
      NETosis: Immunity, Pathogenesis and Therapeutics takes a focused approach to the clinical aspects of NETosis and drug development, bringing critical findings. Chapters introduce NETosis, consider mechanisms and antimicrobial strategies regulating NETosis, examine NETosis in neonates, explore the role of NETosis in autoimmunity, delve into NETosis and other diseases, and present therapeutic approaches for dysregulated NETosis. Since Brinkamm, et al, discovered an unrecognized neutrophil anti-microbial mechanism responsible for the extracellular killing of invading pathogens in 2004, the novel process in which nuclear chromatin de-condenses and DNA is ejected into the extra cellular environment, trapping and inactivating tissue pathogens has rapidly evolved.

    • Dosage Form Design Considerations

      • 1st Edition
      • July 27, 2018
      • English
      • Hardback
        9 7 8 0 1 2 8 1 4 4 2 3 7
      • eBook
        9 7 8 0 1 2 8 1 4 4 2 4 4
      Dosage Form Design Parameters, Volume I, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries.

    • Dosage Form Design Parameters

      • 1st Edition
      • July 25, 2018
      • English
      • Hardback
        9 7 8 0 1 2 8 1 4 4 2 1 3
      • eBook
        9 7 8 0 1 2 8 1 4 4 2 2 0
      Dosage Form Design Parameters, Volume II, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries.

    • New Look to Phytomedicine

      • 1st Edition
      • October 23, 2018
      • Mohd Sajjad Ahmad Khan + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 4 6 1 9 4
      • eBook
        9 7 8 0 1 2 8 1 4 6 2 0 0
      New Look to Phytomedicine: Advancements in Herbal Products as Novel Drug Leads is a compilation of in-depth information on the phytopharmaceuticals used in modern medicine for the cure and management of difficult-to-treat and challenging diseases. Readers will find cutting-edge knowledge on the use of plant products with scientific validation, along with updates on advanced herbal medicine in pharmacokinetics and drug delivery. This authoritative book is a comprehensive collection of research based, scientific validations of bioactivities of plant products, such as anti-infective, anti-diabetic, anti-cancer, immune-modulatory and metabolic disorders presented by experts from across the globe. Step-by-step information is presented on chemistry, bioactivity and the functional aspects of biologically active compounds. In addition, the pharmacognosy of plant products with mechanistic descriptions of their actions, including pathogenicity is updated with information on the use of nanotechnology and molecular tools in relation to herbal drug research.

    • Multivariate Analysis in the Pharmaceutical Industry

      • 1st Edition
      • April 24, 2018
      • Ana Patricia Ferreira + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 1 0 6 5 2
      • eBook
        9 7 8 0 1 2 8 1 1 0 6 6 9
      Multivariate Analysis in the Pharmaceutical Industry provides industry practitioners with guidance on multivariate data methods and their applications over the lifecycle of a pharmaceutical product, from process development, to routine manufacturing, focusing on the challenges specific to each step. It includes an overview of regulatory guidance specific to the use of these methods, along with perspectives on the applications of these methods that allow for testing, monitoring and controlling products and processes. The book seeks to put multivariate analysis into a pharmaceutical context for the benefit of pharmaceutical practitioners, potential practitioners, managers and regulators. Users will find a resources that addresses an unmet need on how pharmaceutical industry professionals can extract value from data that is routinely collected on products and processes, especially as these techniques become more widely used, and ultimately, expected by regulators.

    • Diagnostic and Therapeutic Applications of Exosomes in Cancer

      • 1st Edition
      • May 9, 2018
      • Mansoor M. Amiji + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 1 2 7 7 4 2
      • eBook
        9 7 8 0 1 2 8 1 2 8 0 4 6
      Diagnostic and Therapeutic Applications of Exosomes in Cancer evaluates the potential of exosome content manipulation in the development of novel therapeutics. In recent years, exosomes, the small vesicles produced by all cell types, have been identified as contributors to cancer growth and metastasis. However, due to their unique biophysical properties, they are also being tested for use in therapeutic design and delivery, as well as in diagnostics. This book presents a comprehensive analysis on exosomes, with a main emphasis on their biogenesis and signaling, use as biomarkers, and as tools for imaging, drug delivery and the treatment of cancer.

    • Handbook of Pharmaceutical Wet Granulation

      • 1st Edition
      • August 31, 2018
      • Ajit S. Narang + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 1 0 4 6 0 6
      • eBook
        9 7 8 0 3 2 3 4 8 1 0 3 8
      Handbook of Pharmaceutical Wet Granulation: Theory and Practice in a Quality by Design Paradigm offers a single and comprehensive reference dedicated to all aspects of pharmaceutical wet granulation, taking a holistic approach by combining introductory principles with practical solutions. Chapters are written by international experts across industry, academic and regulatory settings, and cover a wide spectrum of relevant and contemporary wet granulation topics, techniques and processes. The books' focus on process analytical technology, quality by design principles, granulation equipment, modeling, scale-up, control and real time release makes it a timely and valuable resource for all those involved in pharmaceutical wet granulation.

    • Accelerated Predictive Stability (APS)

      • 1st Edition
      • May 14, 2018
      • Fenghe Qiu + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 2 7 8 6 8
      • eBook
        9 7 8 0 1 2 8 0 2 7 8 5 1
      Accelerated Predictive Stability (APS): Fundamentals and Pharmaceutical Industry Practices provides coverage of both the fundamental principles and pharmaceutical industry applications of the APS approach. Fundamental chapters explain the scientific basis of the APS approach, while case study chapters from many innovative pharmaceutical companies provide a thorough overview of the current status of APS applications in the pharmaceutical industry. In addition, up-to-date experiences in utilizing APS data for regulatory submissions in many regions and countries highlight the potential of APS in support of registration stability testing for certain regulatory submissions. This book provides high level strategies for the successful implementation of APS in a pharmaceutical company. It offers scientists and regulators a comprehensive resource on how the pharmaceutical industry can enhance their understanding of a product’s stability and predict drug expiry more accurately and quickly.

    • Biocontamination Control for Pharmaceuticals and Healthcare

      • 1st Edition
      • November 30, 2018
      • Tim Sandle
      • English
      • Paperback
        9 7 8 0 1 2 8 1 4 9 1 1 9
      • eBook
        9 7 8 0 1 2 8 1 4 9 1 2 6
      Biocontamination Control for Pharmaceuticals and Healthcare outlines a biocontamination strategy that tracks bio-burden control and reduction at each transition in classified areas of a facility. This key part of controlling risk escalation can lead to the contamination of medicinal products, hence necessary tracking precautions are essential. Regulatory authorities have challenged pharmaceutical companies, healthcare providers, and those in manufacturing practice to adopt a holistic approach to contamination control. New technologies are needed to introduce barriers between personnel and the environment, and to provide a rapid and more accurate assessment of risk. This book offers guidance on building a complete biocontamination strategy.

Related subjects

Pharmaceutical science