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Books in Neurochemistry

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11-20 of 39 results in All results

Brain Lipids in Synaptic Function and Neurological Disease

  • 1st Edition
  • May 12, 2015
  • Jacques Fantini + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 0 0 1 1 1 - 0
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 0 4 9 2 - 0
Lipids are the most abundant organic compounds found in the brain, accounting for up to 50% of its dry weight. The brain lipidome includes several thousands of distinct biochemical structures whose expression may greatly vary according to age, gender, brain region, cell type, as well as subcellular localization. In synaptic membranes, brain lipids specifically interact with neurotransmitter receptors and control their activity. Moreover, brain lipids play a key role in the generation and neurotoxicity of amyloidogenic proteins involved in the pathophysiology of neurological diseases. The aim of this book is to provide for the first time a comprehensive overview of brain lipid structures, and to explain the roles of these lipids in synaptic function, and in neurodegenerative diseases, including Alzheimer’s, Creutzfeldt-Jakob’s and Parkinson’s. To conclude the book, the authors present new ideas that can drive innovative therapeutic strategies based on the knowledge of the role of lipids in brain disorders.

Chemical Modulators of Protein Misfolding and Neurodegenerative Disease

  • 1st Edition
  • January 12, 2015
  • Pierfausto Seneci
  • English
  • Hardback
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  • eBook
    9 7 8 - 0 - 1 2 - 8 0 1 9 5 9 - 7
This book is a neurochemistry-based companion for Protein Misfolding and Neurodegenerative Diseases: Molecular Targets, an Elsevier title by the same author publishing in December 2014. While the first book focuses on biology and molecular targets, this companion book describes how these targets are regulated by small molecules and disease-modifying compounds. The book begins with a brief introduction to how key proteins become dysfunctional, and each subsequent chapter describes major disease mechanisms in Alzheimer’s and other tauopathies. Properties and development status of these molecular targets and disease mechanisms are thoroughly described, as are small molecule effectors of autophagy and dis-aggregating agents.

The Endocannabinoidome

  • 1st Edition
  • September 18, 2014
  • Vincenzo Di Marzo + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 4 2 0 1 2 6 - 2
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 0 4 2 9 - 6
The Endocannabinoidome: The World of Endocannabinoids and Related Mediators is dedicated to the latest research and studies on endocannabinoids and cannabinoid receptors to illustrate their important role in the discovery of new, endocannabinoid-related, lipid mediators. Written by leading experts across different disciplines, this book focuses on the biochemical and anlayticial aspects of novel lipid signals, their pharmacological activities and their potential utilization for the development of new and effective therapeutic strategies. The first book of its kind, The Endocannabinoidome is a meaningful reference for all those involved in experimental efforts to further the development of this field.

Neuroimmune Signaling in Drug Actions and Addictions

  • 1st Edition
  • Volume 118
  • August 28, 2014
  • Changhai Cui + 2 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 0 1 2 8 4 - 0
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 1 4 3 8 - 7
This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume concentrates on Neuroimmune Signaling in Drug Actions and Addictions.

Dopamine

  • 1st Edition
  • Volume 211
  • June 23, 2014
  • Marco Diana + 2 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 6 3 4 2 5 - 2
  • eBook
    9 7 8 - 0 - 4 4 4 - 6 3 4 2 7 - 6
Progress in Brain Research is a well-established international series examining major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume, concentrates on state-of-the-art of dopamine research: from basic science to clinical applications. It covers topics including thalamostriatal synapses as a substrate for dopamine action; the multilingual nature of dopamine neurons; ethanol-mechanisms along the mesolimbic dopamine system, and much more.Progress in Brain Research is the most acclaimed and accomplished series in neuroscience, firmly established as an extensive documentation of the advances in contemporary brain research. The volumes, some of which are derived from important international symposia, contain authoritative reviews and original articles by invited specialists. The rigorous editing of the volumes assures that they will appeal to all laboratory and clinical brain research workers in the various disciplines: neuroanatomy, neurophysiology, neuropharmacology, neuroendocrinology, neuropathology, basic neurology, biological psychiatry, and the behavioral sciences.

The Role of 5-HT Systems on Memory and Dysfunctional Memory

  • 1st Edition
  • March 11, 2014
  • Alfredo Meneses
  • English
  • eBook
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Drugs acting through 5-HT (5-hydroxytryptamine, or serotonin) systems modulate memory and its alterations, but the mechanisms by which they do so are poorly understood. Agonists and antagonists for 5-HT receptors, as well as serotonin uptake inhibitors, present promnesic (memory-promoting) and/or anti-amnesic effects under different conditions, and 5-HT receptors are also associated with neural changes. The Role of 5-HT Systems on Memory and Dysfunctional Memory: Emergent Targets for Memory Formation and Memory Alterations reviews and summarizes the most recent research related to 5-HT drugs and the mechanisms by which they effect alterations in memory. This latest evidence is reviewed in the context of memory deficits related to brain disorders, such as post-traumatic stress disorder, schizophrenia, post-stroke cognitive dysfunctions, Parkinson’s disease, and infection-induced memory impairments. Written by an expert in the field of memory, The Role of 5-HT Systems on Memory and Dysfunctional Memory provides an introduction to the latest research on 5-HT receptors and their contributions to the physiological and pharmacological basis of memory.

Catecholamine Research in the 21st Century

  • 1st Edition
  • December 5, 2013
  • Lee E. Eiden
  • English
  • Paperback
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  • eBook
    9 7 8 - 0 - 1 2 - 8 0 0 0 7 3 - 1
Through the use of extended graphical abstracts and some traditional text-only abstracts this collection provides, a record of and roadmap to, the research presented at The Tenth International Catecholamine Symposium (XICS) held in September of 2012. Organized around ten general themes, each is introduced by a short overview identifying interesting research programs, results and potential areas of growth. The collection is a roadmap to key research and future opportunities for new catecholamine research programs and will be of interest to neuroscientists and clinical neurologists interested in understanding the current and future state of catecholamine research.

Advances in the Neurochemistry and Neuropharmacology of Tourette Syndrome

  • 1st Edition
  • Volume 112
  • November 27, 2013
  • Davide Martino + 1 more
  • English
  • Hardback
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  • eBook
    9 7 8 - 0 - 1 2 - 4 1 1 5 6 1 - 3
This volume of International Review of Neurobiology brings together cutting-edge research on advances in the neurochemistry and neuropharmacology of Tourette syndrome. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and includes important topics regards tics, neurotransmitters, pharmacology and emerging treatments.

Lipid Metabolism in Signaling Systems

  • 1st Edition
  • Volume 18
  • October 22, 2013
  • John N. Fain + 1 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 8 8 3 2 - 1
Many of the phospholipases and even the receptor for inositol 1,4,5-trisphosphate have recently been cloned and sequenced and play an important role in neurotransmission. Methods developed in recent years for the study of the enzymes and intermediates involved in the regulation of neuronal signal transduction involving phospholipid turnover are presented in this volume.

Thirst and Sodium Appetite

  • 1st Edition
  • December 2, 2012
  • Sebastian Grossman
  • English
  • eBook
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Thirst and Sodium Appetite: Physiological Basis describes the phenomenon of thirst and the mechanisms that define the need for water. Thirst and appetite has generated much study and research about the physiological, endocrinological, and pharmacological mechanisms that influence water intake. However, in this book, other concerns have been emphasized, such as the significance of brain mechanisms in the subject matter. This book, consisting of 11 chapters, starts with a basic description of thirst then to an analysis of basic physiological mechanisms that determine water intake. Another topic also discussed in this book is various experimental paradigms that resulted to the dual-depletion theory of thirst. The neuroanatomical, neuroendocrinological, and neuropharmacological brain mechanisms are covered in three chapters of this book. These brain mechanisms respond to different peripheral signals that stimulate the thirst. The final chapters are dedicated to sodium appetite. Although it has lesser literature than thirst has, there have been significant developments in the understanding of the role of sodium appetite in extracellular thirst. The last chapter reviews the questions that has kept investigators at bay and recommends direction of where future research may go.