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Chemical Modulators of Protein Misfolding and Neurodegenerative Disease

  • 1st Edition - January 12, 2015
  • Author: Pierfausto Seneci
  • Language: English
  • Hardback ISBN:
    9 7 8 - 0 - 1 2 - 8 0 1 9 4 4 - 3
  • eBook ISBN:
    9 7 8 - 0 - 1 2 - 8 0 1 9 5 9 - 7

This book is a neurochemistry-based companion for Protein Misfolding and Neurodegenerative Diseases: Molecular Targets, an Elsevier title by the same author publishing in December… Read more

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This book is a neurochemistry-based companion for Protein Misfolding and Neurodegenerative Diseases: Molecular Targets, an Elsevier title by the same author publishing in December 2014. While the first book focuses on biology and molecular targets, this companion book describes how these targets are regulated by small molecules and disease-modifying compounds. The book begins with a brief introduction to how key proteins become dysfunctional, and each subsequent chapter describes major disease mechanisms in Alzheimer’s and other tauopathies. Properties and development status of these molecular targets and disease mechanisms are thoroughly described, as are small molecule effectors of autophagy and dis-aggregating agents.

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