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Books in Immunology

Elsevier's Immunology collection equips researchers with valuable insights to address the complexities of the immune system and its role in health and disease, offering original research, insightful analysis, and current theory on diagnosing, managing, and advancing treatments for allergies, asthma, and immunologic disorders.

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51-60 of 554 results in All results

System Vaccinology

  • 1st Edition
  • August 20, 2022
  • Vijay Kumar Prajapati
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 8 5 9 4 1 - 7
  • eBook
    9 7 8 - 0 - 3 2 3 - 8 9 7 8 6 - 0
Emergence of new and deadly infectious diseases is significantly deteriorating the human health. Development of vaccine by the scientist has become an important weapon to control the spread of infectious diseases as well as to improve the life expectancy at global level in 20th-21st Century. This book will provide the in-depth knowledge of vaccine history, and development of new strategies to design efficacious and safe vaccine molecule. This book will cover the development of system vaccinology and their applications revolutionize the vaccine discovery. This will provide a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials. My purpose to write this book to educate the students and researchers with modern development in the field of vaccinology and empowering the researcher with new tools and methodology for developing potential and immunogenic vaccines. This book will be helpful to solve the curiosity of science and medical background students related with vaccinology and will be helpful to devise a new vaccine molecule to control the spread of new and emerging pathogens. Systems biology is a rapidly expanding research discipline aiming to integrate multifaceted datasets generated using state-of-the-art high- throughput technologies such as arrays and next-generation sequencing. Combined with sophisticated computational analysis we are able to interrogate host responses to infections and vaccination on a systems level, thus generating important new hypotheses and discovering unknown associations between immunological parameters.

Clinical Immunology

  • 1st Edition
  • August 16, 2022
  • Nima Rezaei
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 8 0 0 6 - 8
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 8 0 0 7 - 5
Clinical Immunology not only introduces the reader to the human immune system, it also covers immunology from clinical manifestation to therapeutic approaches in a wide range of conditions. Each chapter describes an introduction, the clinical manifestations, the immunopathogenesis, diagnosis, lab tests and therapeutic approaches. The book guides clinicians, researchers and students to a better understanding of the matters of immunologic-based diseases that can lead to better decision-making for patients.Because of the growing knowledge regarding the function of immune system in health and disease conditions, clinicians, researchers and students increasingly require an exclusive scientific reference to guide them on matters of immunologic-based diseases. Accordingly, despite the existence of numerous high quality references in basic and cellular/molecular immunology which deeply explain different immunologic mechanisms, there is still a knowledge gap in the field of clinical immunology.

Hepatobiliary Cancers: Translational Advances and Molecular Medicine

  • 1st Edition
  • Volume 156
  • August 10, 2022
  • Alphonse E. Sirica + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 9 8 3 9 2 - 1
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 8 3 9 3 - 8
Hepatobiliary cancer refers to primary malignant tumors originating in cells of the liver, bile ducts, and gallbladder. Globally, primary liver cancer, which includes hepatocellular carcinoma (~75 % of all cases) and intrahepatic biliary cancer or cholangiocarcinoma (~10-15 % 0f all cases) is the 6th most commonly diagnosed cancer and 3rd leading cause of cancer deaths worldwide. The vast majority of these highly malignant cancers are diagnosed at an advanced stage where  treatment options are limited and patient survival outcomes are poor. The biological and therapeutic challenges posed by hepatobililiary cancers such as hepatocellular carcinoma (HCC)  and cholangiocarcinoma (CCA) are daunting, emphasizing a critical need to review and assess current and evolving basic, translational, and clinical research focused on addressing the critical obstacles that continue to limit progress towards achieving significant improvements in HCC and CCA clinical management and patient survival outcomes. Towards this goal, this special edition of Advances in Cancer Research is focused on providing  a comprehensive, timely and authoritative reviews covering such topics of significant scientific and clinical relevance, including hepatobiliary cancer risk mechanisms and risk-predictive molecular biomarkers; causes and functional intricacies of inter- and intratumor heterogeneity; novel insights into the role of tumor microenvironment and key signaling pathways in  promoting hepatobiliary cancer progression, therapeutic resistance and immunosuppression; emerging biomarkers of HCC and CCA prognosis;  advances in molecular genomics for personalizing tumor classification and targeted therapies;  innovative preclinical cell culture modeling for hepatobiliary cancer drug discovery; and current and emerging trends in hepatobiliary cancer molecular therapeutic targeting and immunotherapies.

The Paradox of the Immune System

  • 1st Edition
  • August 3, 2022
  • Louis J. Catania
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 5 1 8 7 - 6
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 5 1 8 8 - 3
The Paradox of the Immune System: Protection, Inflammation, Autoimmune Disease and Beyond provides a provocative approach to immunology as a "double-edged sword." While it is our greatest protector, it is also the cause of chronic inflammation that leads to autoimmune disease, cancer and infectious diseases like COVID-19. Sections cover the basic science of immunology and its intimate genetic associations, biomedical hypotheses asserting immunology as the basis of all human diseases, and elaborate on immunology as "the enemy within us." This engaging, original approach to a science so personal provides new and invaluable understanding on the bioscience that controls our lives.

Microbial Crosstalk with Immune System

  • 1st Edition
  • July 26, 2022
  • Asmita Das
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 6 1 2 8 - 8
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 9 5 7 9 - 5
Our body is not sterile and harbors enumerable microflora that are now being understood to play a complex role in immune regulation and shaping of the immune system in a continuous and dynamic way. In 8 chapters, Microbial Crosstalk with Immune System: New Insights in Therapeutics provides an overall introduction with special focus on how the immune system which is specifically geared to get rid of non-self-antigens, allows numerous microbes to colonize the human body. In the presence of microbes there are several observations that suggest that there are multiple roles that are played by these microbes in tumor progression and shaping of our immune system which is explained at length in subsequent chapters. Microbial Crosstalk with Immune System: New Insights in Therapeutics discusses the emerging mechanisms of immune-therapeutics as well as its limitations while emphasizing the potential role of microbes in shaping immune-therapeutic and evolving novel strategies to deal with any limitations.

Immunology of Recurrent Pregnancy Loss and Implantation Failure

  • 1st Edition
  • July 3, 2022
  • Joanna Kwak-Kim
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 0 8 0 5 - 4
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 0 8 0 6 - 1
Immunology of Recurrent Pregnancy Loss provides doctors and immunologists with the information they need to help couples who experience recurrent pregnancy losses. Sections cover unexplained infertility, repeated in vitro fertilization, embryo transfer failures, history of second or third trimester pregnancy losses of unknown cause, or pregnancy with a history of or active autoimmune and/or alloimmune disease.  Reproductive failure (RF), including recurrent pregnancy losses (RPL) and repeated implantation failures (RIF) is rather a syndrome than a disease caused by multiple etiologies, such as anatomical, endocrine, genetic, infectious, immunological, thrombotic and unexplained etiologies, hence this book strives to present the latest information. In 27 chapters, divided in 5 sections, the book introduces the current update of reproductive immunology topics in RF and provides systematic diagnostic guidelines, systemic and immune etiologies and therapeutic approaches.

Strategies to Mitigate the Toxicity of Cancer Therapeutics

  • 1st Edition
  • Volume 155
  • June 30, 2022
  • David A. Gewirtz + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 9 0 0 8 7 - 4
  • eBook
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Strategies to Mitigate the Toxicity of Cancer Therapeutics, Volume 155 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters, each of which is written by an international board of authors.

Macrophages in the Human Body

  • 1st Edition
  • June 8, 2022
  • Niels Olson Saraiva Camara + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 1 3 8 5 - 8
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 1 3 8 6 - 5
Through recent research, there has been a significant number of findings involving the biology of macrophages. Beyond the 1st line of defense, macrophages have several specific characteristics across different tissues, organs, and systems. Macrophages comprehend a heterogeneous phagocytic population with wide range phenotypes, and tissue-specific functions, such as bone resorption, extracellular matrix production, red blood cells and bacteria removal, among others. Through innate immune receptors macrophages can modulate several pathways that culminate in the production of various types of inflammatory mediators such as chemokines, cytokines, oxygen reactive species, and lipid mediators which ultimately altered the behavior of other cells. Moreover, environment signals modify and induce metabolic reprograming that it alters phenotype and functions.Macrophages in the Human Body: A Tissue Level Approach presents a current overview of the diversity of macrophages across multiple human body systems, their phenotype, function and metabolic characteristics. It covers translational aspects where there is research support to indicate the therapeutic potential.

Nanotheranostics for Treatment and Diagnosis of Infectious Diseases

  • 1st Edition
  • May 21, 2022
  • Keerti Jain + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 1 2 0 1 - 3
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 1 4 6 9 - 7
Nanotheranostics for Treatment and Diagnosis of Infectious Diseases comprises the latest information on the technological advancements made in the field of nanotechnology for application in therapeutics with diagnostic applications. The book focuses on the theranostic applications of nanomaterials in infectious diseases, highlighting that rapid diagnosis, safe and effective treatment and strong preventive measures like vaccines are urgently needed. It compiles all relevant information to help scientists, researchers and students understand the role of nanomaterials, how nanomaterials could be explored simultaneously for therapeutic and diagnostic applications, and how to ensure safety and efficacy of these nanomaterials. Sections cover fundamental concepts, emerging concerns and challenges to combat infectious diseases, the characterization of nanomaterials for theranostic applications, and the toxicity, biocompatibility and regulatory perspectives in the diagnosis and treatment of infectious diseases.

Eosinophil Ultrastructure

  • 1st Edition
  • May 2, 2022
  • Rossana C.N. Melo + 2 more
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 9 9 4 1 3 - 2
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 3 7 5 6 - 7
Eosinophil Ultrastructure: Atlas of Eosinophil Cell Biology and Pathology entirely focuses on eosinophils and their functional roles in inflammation, host defense, and normal homeostatic activities. The book explores the ultrastructure of human eosinophils, highlighting biological processes observed under normal, experimental, and pathological conditions. Created to fill a void in the eosinophil literature, the book includes an extensive array of electron microscopic images that illustrate the diversity of eosinophil morphology. While the atlas is a learning and teaching tool, it is mainly a helpful  resource for researchers to identify distinguishing features and structural changes that arise during studies of human eosinophils. The book also covers the ultrastructure of mouse eosinophils under normal and activation conditions and in the context of representative diseases.

Related subjects

Applied immunology

Basic immunology

Immunological methods

Immunopathogenesis