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Books in Basic immunology

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31-40 of 436 results in All results

Novel Methods and Pathways in Cancer Glycobiology Research

  • 1st Edition
  • Volume 157
  • February 2, 2023
  • Charles J Dimitroff + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 9 9 1 7 7 - 3
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 9 1 7 8 - 0
Cancer glycobiology is a blazing hot area of cancer research with aberrant post-translational glycosylations on lipids and proteins considered critical for cancer development and metastasis.  The NIH/NCI Alliance of Glycobiologists for Cancer Research is a consortium of (10) tumor glycobiology laboratories funded to investigate how cancer-associated glycans (CAG) impact the development and metastasis of cancer.  The hope of this momentous effort is to discover CAGs for use as novel biomarkers to detect early-stage cancer or its aggressive behavior or, alternatively, as novel molecular targets with the promise of a curative approach to cancer therapy.  The mission of the ‘Alliance’ is to study structure and function of CAGs in cancer development and to provide clinically useful biomarkers for detecting cancer early or the potential of metastasis.  This charge has stimulated extensive collaborations across US and International institutions to accelerate discovery of glycan-based biomarkers to the forefront of NCI's efforts to diagnose early-stage cancer and provide curative anti-cancer therapies.  The main goals of these research efforts are: 1.  To identify and study how cancer-associated glycans functionally impact cancer growth and metastasis2.  To identify cancer-associated glycans that can serve as biomarkers for the detection or progression of cancer3.  To develop cancer-associated glycans as novel therapeutic targets for the treatment and cure of cancer This volume consists of (9) chapters, one from each funded laboratory, that reviews new methods and mechanisms  highlighting glycoconjugates and their roles as cancer biomarkers and/or anti-cancer therapeutic targets.

Introductory Immunology

  • 3rd Edition
  • February 2, 2023
  • Jeffrey K. Actor
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 5 3 0 7 - 5
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 3 0 8 - 2
**Selected for Doody’s Core Titles® 2024 in Immunology**Introductory Immunology: Basic Concepts for Interdisciplinary Applications, 3rd Edition, is a completely updated, revised, and expanded concise, conceptual approach to understanding the immune systems as a primary defense to maintain health and homeostasis. This expanded version includes the aspects of microbiology and related immune defense mechanisms important in combating disease, as well critical components related to the field of vaccine development.Immunology as a subject is no longer confined to the realms of "immunology" or "microbiology" studies. Indeed, the subject matter has become increasingly important to understand complex mechanisms found within a wider range of biological systems. This book aims specifically at educated audiences who do not have a deep understanding of medical, biochemical, or cellular knowledge. The overall text will present concepts that portray a comprehensive picture of the natural defenses to infectious agents as well as provide an introduction to mechanisms that lead to autoimmune dysfunction. In addition, immunological diseases will be detailed, with the goal of allowing the readers to gain sufficient knowledge to make sound choices for clinical decisions to affect treatment outcomes.This new edition expands on the existing chapters, focusing on updating the previous text. It has been expanded to include knowledge on effector mechanisms addressing components inherent within cellular responses that are either newly discovered, or missing from the previous edition. It has an extra emphasis on aspects related to mechanisms important in combating microbial agents and critical sections on how vaccines protect against pathogenic invaders to limit associated pathology.The goal is that Introductory Immunology will become the preferred provider of core knowledge in immunology to build a foundation to explore components of the human immune system that work together to confer and understand dysregulation that causes clinical diseases. This book serves as a basic platform to define therapeutic interventions by:creating appreciation for components of the human immune system to work together to confer lifelong protection;providing a core knowledge in immunology to build a foundation to explore mechanisms involved in clinical disease, and defining functional aspects of immunological terms to permit the reader easy access to comprehend specific topics;presenting introduction to complex immunological concepts in a concise and easy manner that relates to clinical disease;breaking down all of immunology into manageable, logically digestible building blocks, and providing a map to explore overlapping mechanisms of immune protective responses;providing a platform to readers without medical, biochemical, or cellular expertise to understand and appreciate how immunology controls homeostasis and protects against pathogens.

Advances in Immunology

  • 1st Edition
  • Volume 156
  • November 19, 2022
  • Frederick W. Alt + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 9 8 9 4 7 - 3
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 8 9 4 8 - 0
Advances in Immunology, Volume 156, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology, with this volume covering self-referential immune recognition through C-type lectin receptors, genetic susceptibility to autoimmunity, activation and regulation of the cGAS-STING pathway and the implications of IL-15 trans-presentation on the immune response.  

Advances in Immunology

  • 1st Edition
  • Volume 155
  • November 7, 2022
  • Frederick W. Alt + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 9 8 9 4 5 - 9
  • eBook
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Advances in Immunology, Volume 155, the latest release in this ongoing serial, highlights new advances in the field with this new volume presenting interesting chapters written by an international board of authors. Sections of note cover B cell/GC material.

Immunological Implications and Molecular Diagnostics of Genitourinary Cancer

  • 1st Edition
  • October 7, 2022
  • Moulay Mustapha Ennaji
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 8 5 4 9 6 - 2
  • eBook
    9 7 8 - 0 - 3 2 3 - 8 5 4 9 7 - 9
Immunological Implications and Molecular Diagnostics of Genitourinary Cancer updates on recent accomplishments, unifying concepts, and future challenges in the study of tumor-associated immune cells, emphasizing genitourinary cancers. The presence of inflammatory immune cells in human tumors raise a fundamental question: How do cancer cells avoid destruction by immune attack? In principle, tumor development can be controlled by cytotoxic innate and adaptive immune cells, however, as tumors develop from neoplastic tissue to clinically detectable tumors, cancer cells evolve different mechanisms. This book covers research on the immunological implications of genitourinary cancer with a comprehensive view, especially surrounding diagnosis and cellular mechanisms.

Translational Autoimmunity, Volume 5

  • 1st Edition
  • September 13, 2022
  • Nima Rezaei
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 8 5 3 8 9 - 7
  • eBook
    9 7 8 - 0 - 3 2 3 - 8 5 3 9 0 - 3
Translational Autoimmunity: Challenges for Autoimmune Diseases, Fifth Edition addresses diagnostic approaches, therapeutic opportunities, and prognostic markers of different autoimmune diseases. This updated volume discusses autotoxicity, systems immunology, the prognostic significance of disease-specific autoantibodies, along with translational research to novel therapeutic policy in autoimmune diseases. From an introduction, to challenges and insights on the systems immunology of infectious and autoimmune diseases, new targets of treatments, and the role of autoantibodies in diagnosis and evolution, this book provides insights on many challenges researchers and clinicians are facing.

Advances in Immunology

  • 1st Edition
  • Volume 154
  • August 26, 2022
  • Frederick W. Alt
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 9 8 9 4 3 - 5
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 8 9 4 4 - 2
Advances in Immunology, Volume 154, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology, with this volume covering Regulatory T Cells in Infection and Factor H and Properdin and their regulation.

Clinical Immunology

  • 1st Edition
  • August 16, 2022
  • Nima Rezaei
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 8 0 0 6 - 8
  • eBook
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Clinical Immunology not only introduces the reader to the human immune system, it also covers immunology from clinical manifestation to therapeutic approaches in a wide range of conditions. Each chapter describes an introduction, the clinical manifestations, the immunopathogenesis, diagnosis, lab tests and therapeutic approaches. The book guides clinicians, researchers and students to a better understanding of the matters of immunologic-based diseases that can lead to better decision-making for patients.Because of the growing knowledge regarding the function of immune system in health and disease conditions, clinicians, researchers and students increasingly require an exclusive scientific reference to guide them on matters of immunologic-based diseases. Accordingly, despite the existence of numerous high quality references in basic and cellular/molecular immunology which deeply explain different immunologic mechanisms, there is still a knowledge gap in the field of clinical immunology.

Hepatobiliary Cancers: Translational Advances and Molecular Medicine

  • 1st Edition
  • Volume 156
  • August 10, 2022
  • Alphonse E. Sirica + 1 more
  • English
  • Hardback
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  • eBook
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Hepatobiliary cancer refers to primary malignant tumors originating in cells of the liver, bile ducts, and gallbladder. Globally, primary liver cancer, which includes hepatocellular carcinoma (~75 % of all cases) and intrahepatic biliary cancer or cholangiocarcinoma (~10-15 % 0f all cases) is the 6th most commonly diagnosed cancer and 3rd leading cause of cancer deaths worldwide. The vast majority of these highly malignant cancers are diagnosed at an advanced stage where  treatment options are limited and patient survival outcomes are poor. The biological and therapeutic challenges posed by hepatobililiary cancers such as hepatocellular carcinoma (HCC)  and cholangiocarcinoma (CCA) are daunting, emphasizing a critical need to review and assess current and evolving basic, translational, and clinical research focused on addressing the critical obstacles that continue to limit progress towards achieving significant improvements in HCC and CCA clinical management and patient survival outcomes. Towards this goal, this special edition of Advances in Cancer Research is focused on providing  a comprehensive, timely and authoritative reviews covering such topics of significant scientific and clinical relevance, including hepatobiliary cancer risk mechanisms and risk-predictive molecular biomarkers; causes and functional intricacies of inter- and intratumor heterogeneity; novel insights into the role of tumor microenvironment and key signaling pathways in  promoting hepatobiliary cancer progression, therapeutic resistance and immunosuppression; emerging biomarkers of HCC and CCA prognosis;  advances in molecular genomics for personalizing tumor classification and targeted therapies;  innovative preclinical cell culture modeling for hepatobiliary cancer drug discovery; and current and emerging trends in hepatobiliary cancer molecular therapeutic targeting and immunotherapies.

Immunology of Recurrent Pregnancy Loss and Implantation Failure

  • 1st Edition
  • July 3, 2022
  • Joanna Kwak-Kim
  • English
  • Paperback
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  • eBook
    9 7 8 - 0 - 3 2 3 - 9 0 8 0 6 - 1
Immunology of Recurrent Pregnancy Loss provides doctors and immunologists with the information they need to help couples who experience recurrent pregnancy losses. Sections cover unexplained infertility, repeated in vitro fertilization, embryo transfer failures, history of second or third trimester pregnancy losses of unknown cause, or pregnancy with a history of or active autoimmune and/or alloimmune disease.  Reproductive failure (RF), including recurrent pregnancy losses (RPL) and repeated implantation failures (RIF) is rather a syndrome than a disease caused by multiple etiologies, such as anatomical, endocrine, genetic, infectious, immunological, thrombotic and unexplained etiologies, hence this book strives to present the latest information. In 27 chapters, divided in 5 sections, the book introduces the current update of reproductive immunology topics in RF and provides systematic diagnostic guidelines, systemic and immune etiologies and therapeutic approaches.

Related subjects

Cellular immunology

Cytokines and lymphokines

Immunogenetics

Immunopharmacology

Molecular immunology