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Books in Immunopharmacology

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    • Calcitonin

      Proceedings of the Symposium on Thyrocalcitonin and the C Cells, London, 17–20 July 1967
      • 1st Edition
      • John McMichael
      • English
      Calcitonin: Proceedings of the Symposium on Thyrocalcitonin and the C Cells presents a critical review of studies on the purification of Alpha and Beta thyrocalcitonin. The book discusses the histopathological investigation on C cells, as well as the nature of parafollicular cells. Some of the topics covered in the text are the pharmacologic and toxicological effects of porcine thyrocalcitonin in animals; the observation of the effect of thyroidectomy in patients with high thyrocalcitonin secretion; and the definition of chronic calcitonin deficiency. The radiological and histological bone changes produced by calcitonin; calcitonin as an ultimobranchial hormone; and the effects of calcium intake levels on the response to exogenous rat are also covered. The book further tackles bone culture studies with thyrocalcitonin; the observation made on the dense granules in bat thyroid parafollicular cells; and the study of the bovine parturient paresis and hypocalcemia. A chapter is devoted to the inhibition of thyrocalcitonin bone resorption in tissue culture. Another section focuses on the methods for secretory granules staining. The book can provide useful information to scientists, immunologists, students, and researchers.

    • Immunopharmacology

      • 1st Edition
      • Volume 66
      • David J Webb
      • English
      This new volume of Advances in Pharmacology explores the current state of Alzheimer's disease research and therapeutics. Chapters cover such topics as the B cell targeted therapies, Lymphotoxin family receptors in inflammation, and allergic inflammation and thymic stromal lymphopoietin. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.

    • Immunopharmacology of Platelets

      • 1st Edition
      • M. Joseph
      • English
      Platelets have long been the subject of much investigation in the areas of vascular physiology, biochemistry, immunology and physiopathology. Their ability to react to environmental stimuli, to modify their shape and metabolism despite being anuclear, has fascinated scientists.This volume looks specifically at the involvement of blood platelets outside their 'classical' field of application, in the physiopathological mechanics of allergy and inflammation. The coverage includes the role of platelets in bacterial, parasitic and viral diseases and in tumour cell interactions.

    • Immunopharmacology of Free Radical Species

      • 1st Edition
      • English
      Free radicals have been implicated in a entire host of different human disease states, which suggests that although they may not have a pivotal causal role, they are involved in the perpetuation of disease. In recentyears, it has become evident that although free radicals most certainly do have this role in perpetuating inflammatory reactions, they have perhaps a far more important role in acting as second messenger systems to maintain normal cell function. It is theperturbations of these reactions which pose the most intriguing therapeutic challenges. This volume deals with various basic mechanisms of free radical processes and injury. The emphasis in each case is on potential therapeutic strategies developing fromthis new knowledge.

    • Immunopharmacology of the Gastrointestinal System

      • 1st Edition
      • John L. Wallace
      • English
      Diseases of the digestive system have a higher morbidity rate than any other group of disorder. There is a growing body of evidence that the immune system participates in the pathogenesis of a wide range of these diseases, including peptic ulcer disease and the gastropathy induced by nonsteroidal anti-inflammatory drugs (NSAIDS). For these reasons, efforts to develop novel therapies for digestive diseases are increasingly focused on the immune system. This volume reviews the immunopharmacology of the gastrointestinal tract at four distinct levels: Immunomodulation at a cellular level Cellular targers for immunomodulating drugs Specific classes of inflammatory mediators Utility and mechanisms of action of glucocorticoids in the treatment of diseases of the gastrointestinal tract.