Books in Drug discovery

Elsevier's Drug Delivery collection is an indispensable resource for scientists and researchers in the pharmaceutical field, exploring the administration of pharmaceutical compounds for therapeutic effects from molecule identification to medication development. It provides comprehensive coverage, including crucial aspects such as drug screening, medicinal chemistry, and preclinical safety assessments. Highlighting emerging trends like precision medicine, AI applications, immunotherapy, and innovative delivery systems, the collection offers insights into the latest advancements and their impact on healthcare.

Books Journals

1-10 of 53 results in All results

Drug Discovery in the Microbiome

1st Edition
January 1, 2026
Amelia Palermo + 1 more
English

Drug Discovery in the Microbiome: Discovery and translation of microbiome therapeutics provides a comprehensive outlook on novel therapeutic opportunities arising from microbiome research. This book also tackles aspects that uniquely pertain to the development and translation of therapeutics targeting the microbiome. Recent research has pointed to the microbiome as the largest untapped druggable space residing within the human body, which offers an unprecedented opportunity for the development of effective and well tolerated therapeutics. The coverage includes 30 chapters, grouped into seven main parts. Included are topics pertaining microbiome science, such as: the foundations of the human microbiome field and the lates state-of-the-art translational research approaches, intervention types, intervention personalization, and integration of the microbiome into a coherent model of inter-organ and system-scale interactions within the host. The book also covers novel bioinformatic and data modeling strategies for integrating microbiome data at the systems level, for facilitating data interpretation, for streamlining the development of precision prebiotic, probiotic, dietary, and small molecule interventions targeting the microbiome. Finally, it includes expert opinions on the reassessment of traditional drug development standards and practices in the context of the gut microbiome. Pharmacologists, pharmaceutical scientists and microbiologists will benefit from the foundations of microbiome science, and the development of therapeutics targeting the microbiome. The authors highlight the need for an end-to-end reassessment of the drug development pipeline, including preclinical and clinical trial design, drug-drug, drug-microbe, and drug-diet interaction assessments (i.e., context-dependent interactions), and regulatory standards. Clinicians involved in microbiome therapeutics will also benefit from the breadth of coverage in this book.

Synthesis of Best-Seller Drugs

2nd Edition
January 1, 2026
Ruben Vardanyan + 1 more
English

Synthesis of Best-Seller Drugs 2e provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field.

Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders

2nd Edition
September 1, 2025
Adeboye Adejare
English

"Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer’s Disease, 2nd Edition" examines the drug discovery process for neurodegenerative diseases by focusing specifically on Alzheimer’s Disease and illustrating the paradigm necessary to ensure future research and treatment success. The new edition of this book is updated with the most recent developments around the therapeutic strategies for drug discovery like amyloid hypothesis, tau, apo E, insulin, and others. It also includes a new chapter on drug delivery to the brain. The content covers diagnosis, epidemiology, drug discovery strategies, current therapeutics, and much more to provide a holistic approach to the discovery, development, and treatment of Alzheimer’s Disease. Through its coverage of the latest research in targeted drug design, preclinical studies, and mouse and rat models, the book is a must-have resource for all pharmaceutical scientists, pharmacologists, neuroscientists, and clinical researchers working in this area. Pharmaceutical researchers will benefit from the updated coverage on therapeutic approaches to neurodegenerative diseases like Alzheimer’s disease, Parkinson’s disease, Amyotrophic lateral sclerosis, multiple sclerosis, frontotemporal disorder, Huntington’s diseases and many more. Patients and advocacy groups can also benefit from the overview of current treatment options and the scientific progress in the field.

Anti-Obesity Drug Development

1st Edition
May 1, 2025
Fadia Salah Youssef + 1 more
English

"Anti-Obesity Drug Development: Physiology, Pharmacology and Drug Delivery" is a complete reference for pharmaceutical researchers in this key area of research and clinical development. The contents of the book are organized in four parts. The first provides an overview of the foundations and historical development of anti-obesity drugs, including extensive discussion of comorbidities and how they impact drug activity and efficacy. Part two is dedicated to the drug targets involved in the progression of obesity treatment. These include GLPRI and GIPR agonists, Incretin/Glucagon, RM-493 and Liraglutide, Pramlintide and metreleptin, Growth Hormone, FXR and GPR131, and the Gut Microbiota. Part three discusses the most common drugs available in the market and their pharmacological parameters. The final part of the book covers all natural products known to have scientific evidence on the treatment of obesity. "Anti-Obesity Drug Development: Physiology, Pharmacology and Drug Delivery" is the perfect reference for pharmacology researchers and those involved in new drug development both in academic and corporate environments. Research-physicians, endocrinologists, and nutritionists will also benefit from the comprehensive overview of treatments covered in this book.

Medicinal Chemistry and Drug Development

1st Edition
January 1, 2025
Gang Liu
English

Drug/medicinal chemistry runs through all stages of drug development, including the discovery of active compounds, research on the pharmacological properties of molecules and confirmation of drug targets. "Medicinal Chemistry and Drug Development" describes the key events and roles of medicinal chemistry in the discovery and development of lead compounds into drugs (including target identification). It achieves this by using 30 case studies.

Intelligent Nanobiosystems in Medicine and Healthcare, Volume 1

1st Edition
December 1, 2024
Vijay Mishra + 2 more
English
Paperback
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eBook
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Intelligent Nanobiosystems in Medicine and Healthcare, Volume One: Fundamentals, Fabrication and Commercialization provides an overview of recent progress in the nanobiosystems arena, helping readers design and develop novel drug delivery systems and devices that take advantage of recent advances in nanomedical technologies. The book explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advancement in cutting-edge nanomedical technologies. It highlights established research and technology on intelligent nanobiosystems, their rapidly emerging aspects, and future research directions. Sections cover nanobiosystems, explore nano candidates and fabrication aspects, and delve into the challenges of commercialization.This book will be a useful resource for researchers and postgraduate students in pharmaceutical sciences and biotechnology as well as medical professionals, biologists, chemists, materials scientists, clinical researchers, biochemical and biomedical engineers working both in academia and industry.

Privileged Scaffolds in Drug Discovery

1st Edition
July 19, 2023
Bin Yu + 2 more
English
Paperback
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eBook
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Privileged Scaffolds in Drug Discovery is the most complete and up-to-date work in the area. Covering a wide range of privileged structures, it is a perfect reference for scientists involved in targeted drug development.The editors recruited experts from several prestigious Chinese institutions to cover the areas of antiviral drugs, chalcone, pyrimidine, (benz)imidazoles, natural product-derived privileged scaffolds, N-Sulfonyl carboxamides, kinase inhibitors, antitumor molecules, antineurodegenerative drugs, triazoles, oxazolidinone, indole and indoline scaffolds, tigliane diterpenoids, peptide and peptide-based drugs, quassinoids, and others including pseudonatural products, macrocycles, stable peptides and peptidomimetics. The book also explores scaffolds in drug molecules approved in recent years.Privileged Scaffolds in Drug Discovery is a complete reference for researchers in drug discovery and organic synthesis, in academic and corporate settings, who are investigating privileged structures upon which to base new drugs. Researchers in medicinal chemistry and chemical biology will also find the contents of this book valuable.

Managing the Drug Discovery Process

2nd Edition
March 9, 2023
Susan Miller + 5 more
English
Paperback
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eBook
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Managing the Drug Discovery Process, Second Edition thoroughly examines the current state of pharmaceutical research and development by providing experienced perspectives on biomedical research, drug hunting and innovation, including the requisite educational paths that enable students to chart a career path in this field. The book also considers the interplay of stakeholders, consumers, and drug firms with respect to a myriad of factors. Since drug research can be a high-risk, high-payoff industry, it is important to students and researchers to understand how to effectively and strategically manage both their careers and the drug discovery process. This new edition takes a closer look at the challenges and opportunities for new medicines and examines not only the current research milieu that will deliver novel therapies, but also how the latest discoveries can be deployed to ensure a robust healthcare and pharmacoeconomic future. All chapters have been revised and expanded with new discussions on remarkable advances including CRISPR and the latest gene therapies, RNA-based technologies being deployed as vaccines as well as therapeutics, checkpoint inhibitors and CAR-T approaches that cure cancer, diagnostics and medical devices, entrepreneurship, and AI. Written in an engaging manner and including memorable insights, this book is aimed at anyone interested in helping to save countless more lives through science. A valuable and compelling resource, this is a must-read for all students, educators, practitioners, and researchers at large—indeed, anyone who touches this critical sphere of global impact—in and around academia and the biotechnology/pharmaceutical industry.

Bartfai & Lees’ Drug Discovery

2nd Edition
October 1, 2022
Tamas Bartfai + 1 more
English

Antioxidants Effects in Health

1st Edition
June 16, 2022
Seyed Mohammad Nabavi + 1 more
English
Paperback
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eBook
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Antioxidants Effects in Health: The Bright and the Dark Side examines the role that antioxidants play in a variety of health and disease situations. The book discusses antioxidants’ historical evolution, their oxidative stress, and contains a detailed approach of 1) endogenous antioxidants, including endogenous sources, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; 2) synthetic antioxidants, including sources, chemistry, bioavailability, legal status, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; and 3) natural antioxidants, including sources, chemistry, bioavailability, mechanisms of action, possible prooxidant activity; beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies. Throughout the boo, the relationship of antioxidants with different beneficial and detrimental effects are examined, and the current controversies and future perspectives are addressed and explored. Antioxidants Effects in Health: The Bright and the Dark Side evaluates the current scientific evidence on antioxidant topics, focusing on endogenous antioxidants, naturally occurring antioxidants and synthetic antioxidants. It will be a helpful resource for pharmaceutical scientists, health professionals, those studying natural chemistry, phytochemistry, pharmacognosy, natural product synthesis, and experts in formulation of herbal and natural pharmaceuticals.