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Elsevier

Elsevier

  • Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis

    • 1st Edition
    • Volume 71
    • English
    Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis deals with the use of high-resolution mass spectrometry (MS) in the analysis of small organic molecules. Over the past few years, time-of-flight (ToF) and Orbitrap MS have both experienced tremendous growth in a great number of analytical sectors and are now well established in many laboratories where high requirements are placed on analytical performance. This book gives a head-to-head comparison of these two technologies that compete directly with each other. As users with hands-on experience in both techniques, the authors provide a balanced description of the strengths and weaknesses of both techniques. In the vast majority of cases, ToF-MS and Orbitrap-MS have been used for qualitative purposes, mainly identification of discrete molecular entities such as drug metabolites or transformation products of environmental contaminants. This paradigm is now changing as quantitative capabilities are increasingly being explored, as are non-target approaches for unbiased broad-scope screening. In view of the continuous innovation of high-resolution MS instrument manufacturers in designing and developing more powerful machines, technological advances in both hardware and software are considerable, with many novel applications. This book summarizes and analyzes these trends. The compilation of selected examples from diverse analytical fields will allow the readers to discover not only the potential of high-resolution MS in their sector, but also shows advances in other fields that rely on hi-res MS.

  • Schizophrenia: Advances and Current Management, An Issue of Psychiatric Clinics of North America

    • 1st Edition
    • Volume 39-2
    • Peter F. Buckley
    • English
    This issue of the Psychiatric Clinics, edited by Dr. Peter F. Buckley, examines advances and current management in the treatment of Schizophrenia. The topics covered in this issue include, but are not limited to: Duration of Untreated Psychosis (DUP) and Longitudinal Perspectives on DUP; Neuroinflammation and Schizophrenia; Emerging Treatments for Schizophrenia; Treatment-Resistant Schizophrenia; Comorbidities and Schizophrenia; Recovery from Schizophrenia; and the latest in schizophrenia research.

  • Sepsis, An Issue of Clinics in Chest Medicine

    • 1st Edition
    • Volume 37-2
    • Julie A. Bastarache + 1 more
    • English
    This issue of Clinics in Chest Medicine focuses on Sepsis. Articles include: The changing epidemiology and definition of sepsis; risk stratification and prognosis in sepsis: what have we learned from biomarkers and microarrays?;Sepsis outside the ICU: development and implementation of sepsis alert systems; The use of ultrasound in caring for the septic patient; Sepsis resuscitation: Fluid choice and dose; Beyond the golden hours: caring for the septic patient after the initial resuscitation; Vasopressors during sepsis: selection and targets; Dysglycemia and glucose control during sepsis; Cardiac function and dysfunction in sepsis;Goal Directed Resuscitation in Septic Shock; and more!

  • Neurology Self-Assessment: A Companion to Bradley's Neurology in Clinical Practice

    • 1st Edition
    • Justin T. Jordan + 2 more
    • English
    Get the most comprehensive, up-to-date guidance available for exam prep with help from Neurology Self-Assessment. Written by Drs. Justin T. Jordan, David R. Mayans, and Michael J. Soileau, this companion volume to Bradley’s Neurology in Clinical Practice thoroughly covers the core and subspecialty topics you’ll encounter on your exam, along with detailed answer explanations and cross-references to Bradley’s. With a focus on assessing subspecialty strengths and weaknesses, it’s the ideal preparation for board certification, maintenance of certification, in-training examinations, and neurology examinations for medical students.

  • Aspinall's Complete Textbook of Veterinary Nursing

    • 3rd Edition
    • Nicola Lakeman (Previously Ackerman) + 1 more
    • English
    The third edition of Aspinall’s Complete Textbook of Veterinary Nursing is the ideal text for both student and qualified veterinary nurses as it covers the entire veterinary nursing syllabus. Now written in the main by veterinary nurses this book comprehensively covers all aspects of the veterinary nursing role from client communication to nutritional support. All chapters have been revised in line with changes in legislation and regulation, but also theoretical and practical aspects. Greater emphasis on the veterinary practice structure including the role of corporate businesses and use of social media bring this edition fully up to date. The new edition welcomes Nicola Ackerman as principal editor. Nicola is past officer of the BVNA and editor of the Veterinary Nursing Journal, and is currently the chair of The Pet Obesity Taskforce. Nicola is a winner of several awards including the Blue Cross/BVNA Veterinary Nurse of the Year 2010. Nicola was the first Veterinary Nurse in the UK to become a veterinary nurse specialist in nutrition.

  • Brown's Regional Anesthesia Review

    • 1st Edition
    • Ehab Farag + 1 more
    • English
    Brown's Regional Anesthesia Review features hundreds of review questions and answers covering all of the content found within the 5th edition of Brown’s Atlas for Regional Anesthesia. Ideal for residents in training, regional anesthesia fellows, and practicing anesthesiologists alike, this companion resource was designed to be used in preparation for anesthesia exams or as a general review of the parent text.

  • Pain Management, An Issue of Anesthesiology Clinics

    • 1st Edition
    • Volume 34-2
    • Perry G. Fine + 1 more
    • English
    This issue of Anesthesiology Clinics focuses on Pain Management.Topics will include: The Pain Treatment Imperative: Developments in the 21st Century, Imaging Pain, The Opioid Conundrum, Advancing the Pain Agenda in the Veteran Population ,Interventional Treatments of Cancer Pain, Integrating Pain Care into the Peri-Operative Surgical Home, Pain Care in the ED, Sleep and Pain, Can Chronic Pain be Prevented?, The Use of Outcome Data to Improve Patient Outcomes, and Impact of State-based Pain Legislation on Patient Outcomes.

  • Antibiotic Resistance: Challenges and Opportunities, An Issue of Infectious Disease Clinics of North America

    • 1st Edition
    • Volume 30-2
    • Robert A. Bonomo + 1 more
    • English
    For many years, physicians and the public assumed that the discovery of new antimicrobial agents would outpace the ability of bacteria to mutate and develop drug resistance. Yet the development of new antibiotics has not kept up with bacterial evolution, especially since the late 1990’s. At that time a multitude of pharmaceutical companies abandoned antibiotic research because of strong economic disincentives. For example, it is challenging for these companies to recuperate the investment (typically in the hundreds of millions of dollars) made in developing a new antibiotic, which is typically prescribed for a few days, compared to drugs that treat chronic conditions like heart disease or mental illness. This situation has led the U.S. federal government to take a more active lead in addressing antibiotic resistance. Recently, the White House announced an action plan that includes improving surveillance, developing better diagnostic tools, accelerating drug development, and improving global coordination of antibiotic resistance issues. Equally important is the $1.2 billion dollars that has been pledged to fund these efforts. While we await the implementation of new policies, this issue of Infectious Disease Clinics of North America brings together leading authorities in the field of antibiotic resistance who discuss current issues including antibiotic stewardship, the changing role of the microbiology laboratory in determining antibiotic resistance in gram-negative pathogens, the continuing spread of metallo-β-lactamases... ESBLs and KPCs, antibiotic options for treating resistant gram-negative infections such as colistin and tigecycline, resistance mechanisms and new treatment options for Mycobacterium tuberculosis, emerging resistance mechanisms in aminoglycosides, issues with antibiotic resistance in immunocompromised patients, new β-lactamase inhibitors in the clinic, and resistance in VRE and Staphylococcus aureus. Additionally, combination therapy for resistant gram-negative infections has been advocated by some authorities and the advantages and disadvantages of this strategy will be reviewed.

  • Sedation and Sleep in Critical Care: An Update, An Issue of Critical Care Nursing Clinics

    • 1st Edition
    • Volume 28-2
    • Jan Foster
    • English
    Sedation is a necessary component of care for critically ill and injured individuals. Sedatives assist in coping with mechanical ventilation and other invasive devices, and help patients tolerate procedures and noxious stimuli in the intensive care unit. Sedatives are also useful in the control of agitation and delirium. In addition to fundamental humane reasons, calming patients with sedatives provides physiologic benefits, such as reducing oxygen consumption expended during restlessness, and prevents dislodgement of life-preserving tubes and catheters. When administering sedatives to manage critically ill patients, clinicians must be cognizant of the many complex issues surrounding their use. This issue, edited by Consulting Editor, Dr. Jan Foster, provides current updates in this area, including new guidelines and a focus on delirium.

  • Psychiatric Mental Health Nursing, An Issue of Nursing Clinics of North America

    • 1st Edition
    • Volume 51-2
    • Deborah Antai-Otong
    • English
    Nurses are challenged to understand the scientific bases of psychiatric disorders and treatment implications that modify behavior and improve functional status and quality of life for clients and their significant others. This challenge extends to integration of scientific knowledge into the biological, functional, and psychosocial distress experienced by persons with mental disorders. The primary strength of this issue is its broad focus and synthesis of scientific knowledge into psychiatric mental health practice. The initial section centers on technological advances and the art of psychiatric mental health nursing and legal considerations when caring for persons with mental disorders. The following section provides discussions of various psychiatric disorders, including anxiety and mood disorders, acute psychosis, attention deficit disorders, substance-related disorders, eating disorders, and borderline personality disorder. The remaining section focuses on special populations and treatment concerning children and adolescents and families in crisis, geriatric emergencies, adverse drug reactions, and suicide. Each article integrates innovative treatment modalities, including pharmacotherapy and psychotherapeutic interventions such as psychoeducation, family involvement, and psychosocial rehabilitation. This issue will provide timely updates in these areas and be a go-to source for mental health and psychiatric nurses.

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