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Elsevier

Elsevier

  • CRISPR and RNAi Systems

    Nanobiotechnology Approaches to Plant Breeding and Protection
    • 1st Edition
    • Kamel A. Abd-Elsalam + 1 more
    • English
    Plants are vulnerable to pathogens including fungi, bacteria, and viruses, which cause critical problems and deficits. Crop protection by plant breeding delivers a promising solution with no obvious effect on human health or the local ecosystem. Crop improvement has been the most powerful approach for producing unique crop cultivars since domestication occurred, making possible the main innovations in feeding the globe and community development. Genome editing is one of the genetic devices that can be implemented, and disease resistance is frequently cited as the most encouraging application of CRISPR/Cas9 technology in agriculture. Nanobiotechnology has harnessed the power of genome editing to develop agricultural crops. Nanosized DNA or RNA nanotechnology approaches could contribute to raising the stability and performance of CRISPR guide RNAs. This book brings together the latest research in these areas. CRISPR and RNAi Systems: Nanobiotechnology Approaches to Plant Breeding and Protection presents a complete understanding of the RNAi and CRISPR/Cas9 techniques for controlling mycotoxins, fighting plant nematodes, and detecting plant pathogens. CRISPR/Cas genome editing enables efficient targeted modification in most crops, thus promising to accelerate crop improvement. CRISPR/Cas9 can be used for management of plant insects, and various plant pathogens. The book is an important reference source for both plant scientists and environmental scientists who want to understand how nano biotechnologically based approaches are being used to create more efficient plant protection and plant breeding systems.

  • Distributed Energy Resources in Local Integrated Energy Systems

    Optimal Operation and Planning
    • 1st Edition
    • Giorgio Graditi + 1 more
    • English
    Distributed Energy Resources in Local Integrated Energy Systems: Optimal Operation and Planning reviews research and policy developments surrounding the optimal operation and planning of DER in the context of local integrated energy systems in the presence of multiple energy carriers, vectors and multi-objective requirements. This assessment is carried out by analyzing impacts and benefits at local levels, and in distribution networks and larger systems. These frameworks represent valid tools to provide support in the decision-making process for DER operation and planning. Uncertainties of RES generation and loads in optimal DER scheduling are addressed, along with energy trading and blockchain technologies. Interactions among various energy carriers in local energy systems are investigated in scalable and flexible optimization models for adaptation to a number of real contexts thanks to the wide variety of generation, conversion and storage technologies considered, the exploitation of demand side flexibility, emerging technologies, and through the general mathematical formulations established.

  • Myeloproliferative Neoplasms, An Issue of Hematology/Oncology Clinics of North America

    • 1st Edition
    • Volume 35-2
    • John Mascarenhas + 3 more
    • English
    This issue of Hematology/Oncology Clinics, guest edited by Drs. Ronald Hoffman, Ross Levine, John Mascarenhas, and Raajit Rampal, is dedicated to Myeloproliferative Neoplasms. This issue is one of six selected each year by the series consulting editors, Drs. George P. Canellos and Edward J. Benz. Topics in this issue include—but are not limited to— Overview of pathophysiology and potential drug targets, The role of the megakaryocyte, Epigenetics, Genetics, Novel technologies for understanding MPN biology, Important pathology considerations, Current Clinical investigations, Quality of life, Application of stem cell therapy, Immunotherapy approaches, Clinical unmet needs in ET/PV, Accelerated and blast phase MPNs, Epidemiology, Thrombotic and hemorrhagic complications, Murine modeling, The microenvironment in MPNs, MDS/MPN overlap syndrome, and Advancing effective clinical trial designs.

  • Climate Change

    Observed Impacts on Planet Earth
    • 3rd Edition
    • Trevor Letcher
    • English
    Climate Change: Observed Impacts on Planet Earth, Third Edition, brings together top global researchers across many disciplines to provide a comprehensive review on the complex issue of climate change and weather patterns. The third edition continues its tradition of focusing on the science and evidence on this highly politicized topic. Every chapter is updated, with this new edition featuring new chapters on topics such as glacier melt, the impacts of rising temperatures, extreme weather, modeling techniques, biodiversity, and more. This book is essential for researchers, environmental managers, engineers, and those whose work is impacted by, or tied to, climate change and global warming.

  • Green Synthetic Approaches for Biologically Relevant Heterocycles

    Volume 1: Advanced Synthetic Techniques
    • 2nd Edition
    • Goutam Brahmachari
    • English
    Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume One: Advanced Synthetic Techniques reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume One explores advanced synthetic techniques, with each chapter presenting in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles that are classified on the basis of ring-size and/or the presence of heteroatoms. Techniques covered range from high pressure cycloaddition reactions and microwave irradiation to sustainable one-pot domino reactions. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry.

  • Process Safety Calculations

    • 2nd Edition
    • Renato Benintendi
    • English
    Process Safety Calculations, Second Edition remains to be an essential guide for students and practitioners in process safety engineering who are working on calculating and predicting risks and consequences. The book focuses on calculation procedures based on basic chemistry, thermodynamics, fluid dynamics, conservation equations, kinetics and practical models. It provides helpful calculations to demonstrate compliance with regulations and standards, such as Seveso directive(s)/COMAH, CLP regulation, ATEX directives, PED directives, REACH regulation, OSHA/NIOSH and UK ALARP, along with risk and consequence assessment, stoichiometry, thermodynamics, stress analysis and fluid-dynamics. This fully revised, updated and expanded second edition follows the same organization as the first, including the original three main parts, Fundamentals, Consequence Assessment and Quantitative Risk Assessment. However, the latter part is significantly expanded, including an appendix consisting of five fundamental thematic areas belonging to the risk assessment framework, including in-depth calculations methodologies for some fundamental monothematic macro-areas of process safety.

  • Climate Change and Extreme Events

    • 1st Edition
    • Ali Fares
    • English
    Climate Change and Extreme Events uses a multidisciplinary approach to discuss the relationship between climate change-related weather extremes and their impact on human lives. Topics discussed are grouped into four major sections: weather parameters, hydrological responses, mitigation and adaptation, and governance and policies, with each addressed with regard to past, present and future perspectives. Sections give an overview of weather parameters and hydrological responses, presenting current knowledge and a future outlook on air and stream temperatures, precipitation, storms and hurricanes, flooding, and ecosystem responses to these extremes. Other sections cover extreme weather events and discuss the role of the state in policymaking. This book provides a valuable interdisciplinary resource to climate scientists and meteorologists, environmental researchers, and social scientists interested in extreme weather.

  • Biomass, Biofuels, Biochemicals

    Circular Bioeconomy—Current Developments and Future Outlook
    • 1st Edition
    • Ashok Pandey + 2 more
    • English
    Biomass, Biofuels, Biochemical: Circular Bioeconomy: Current Developments and Future Outlook presents the views of experienced academicians and researchers working in the area of the circular bioeconomy. This book presents an assortment of Resource recovery, Waste Biorefineries, Bio-electrochemical systems, Biopolymers and Green solvents, Bio-adsorbents, and Technology transfer topics. Environmental engineers, biotechnologists, science graduates, chemical engineers, industrial experts and policymakers working in these areas will find the information on the circular economy and its important part in developing low carbon and resource-productive economies very informative. Methodologies and beneficial strategic approaches to address the usage of wastes from agriculture, co-products, and by-products are also discussed.

  • Green Synthetic Approaches for Biologically Relevant Heterocycles

    Volume 2: Green Catalytic Systems and Solvents
    • 2nd Edition
    • Goutam Brahmachari
    • English
    Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume Two: Green Catalytic Systems and Solvents reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume Two explores green catalytic systems and solvents and the techniques surrounding this approach, including metal and magnetic catalysis to organocatalysis and solid acid catalysis, cycloaddition reactions, and varied approaches using ionic liquids. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry.

  • Abdominal Imaging

    Case Review Series
    • 1st Edition
    • Manjiri Dighe + 2 more
    • English
    Master the critical imaging content you need to know with this newly consolidated title in the popular Case Review series. Abdominal Imaging offers a highly illustrated, case-based preparation for board review to help residents and recertifying radiologists succeed on exams, demonstrate a clinical understanding of gastrointestinal and genitourinary imaging, and improve imaging accuracy and interpretation. Cases include both common and difficult-to-diagnos... disorders including gallbladder diseases, pancreatitis and pancreatic masses, staging and identification of gynecologic malignancies, fluoroscopy findings in GI and GU diseases, and much more.

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