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Elsevier

  • Fused Pyrimidine-Based Drug Discovery

    • 1st Edition
    • Raj Kumar
    • English
    Fused Pyrimidine-Based Drug Discovery covers all categories of fused-pyrimidines along with pharmacological and in silico studies. It covers the chemistry and biological activities, as well as the design of novel fused-pyrimidine scaffolds. N-Heterocyclic scaffolds are found in most known drug candidates, and are of interest to medicinal and organic chemists to design, synthesize and evaluate their biological properties. A variety of fused-pyrimidine molecules have been synthesized and extracted from natural resources, and are found to exhibit various biological activities such as antifolates, anticancer agents, analgesics, antimetabolites, CNS active agents and many more. Some of these scaffolds like purines are also known to have involvement in biological processes and are part of the framework of genetic material. This book focuses on the classification, structural chemistry, and chemical and physical properties along with various approaches for their synthesis. This book is ideal for researchers in organic chemistry both in academic and industrial settings, postgraduates in chemistry and medicinal chemistry.

  • Atomically Precise Metal Nanoclusters

    • 1st Edition
    • Thalappil Pradeep
    • English
    Atomically Precise Metal Nanoclusters discusses the host of exciting properties that can be better harnessed with a solid understanding of their different structures and subsequent properties at the molecular level. The book delves into the foundational chemistry of numerous key atomically precise clusters and provides guidance on key approaches employed to examine them. Beginning with an introduction to the properties and fundamental nano-chemistry of atomically precise metal nanoclusters, the book then explores key approaches for their synthesis, examination and modification, including chromatography, mass spectrometry, single crystal diffraction, electron microscopy and computational approaches. A final section covers specific nanoclusters and cluster systems. User will find the important knowledge of an experienced team of contributors who provide a detailed guide to understanding, investigating and utilizing these useful structures that is ideal for anyone working in related fields.

  • Cellulases in the Biofuel Industry

    • 1st Edition
    • Pratima Bajpai
    • English
    Cellulases in the Biofuel Industry discusses how the properties of cellulases affects the quality of the biofuels produced. Heralded as the solution to humanity’s energy problem and the savior of the world’s climate, extensive research is being carried out on biofuels but there are still gaps in our understanding. This book presents cost-effective and current scenarios for cellulase production in the biofuel industry, including the most recent advancements for obtaining cellulases with higher activity on pre-treated biomass substrates by screening and sequencing new organisms, engineering cellulases with improved properties, and by identifying proteins that can stimulate cellulases. The mechanism and efficiency of the cellulase enzyme system on cellulose is discussed with the specific classification of each cellulase enzyme, as well as explanations of the limitation of cellulases in terms of their production processes, efficiency and practical applications to biofuels. Various approaches to improve the production and efficiency of the cellulase enzyme system are evaluated, along with the current limitations that are hampering cost-effective production of cellulase and guidance on how these limitations might be resolved.

  • Tribology of Polymers, Polymer Composites, and Polymer Nanocomposites

    • 1st Edition
    • Soney C. George + 4 more
    • English
    Approx.482 pages

  • Imaging of Diffuse Lung Disease, An Issue of Radiologic Clinics of North America

    • 1st Edition
    • Volume 60-6
    • Stephen Hobbs
    • English
    In this issue of Radiologic Clinics, guest editor Dr. Stephen B. Hobbs brings his considerable expertise to the topic of Imaging of Diffuse Lung Disease. Top experts in the field offer a comprehensive overview of the imaging of every major diffuse lung disease, providing expert coverage of smoking- and vaping-related diffuse lung disease, advances in childhood interstitial lung disease, the use of artificial intelligence in imaging; and more.

  • Microfluidics

    Modeling, Mechanics and Mathematics
    • 2nd Edition
    • Bastian E. Rapp
    • English
    Microfluidics: Modeling, Mechanics and Mathematics, Second Edition provides a practical, lab-based approach to nano- and microfluidics, including a wealth of practical techniques, protocols and experiments ready to be put into practice in both research and industrial settings. This practical approach is ideally suited to researchers and R&D staff in industry. Additionally, the interdisciplinary approach to the science of nano- and microfluidics enables readers from a range of different academic disciplines to broaden their understanding. Alongside traditional fluid/transport topics, the book contains a wealth of coverage of materials and manufacturing techniques, chemical modification/surface functionalization, biochemical analysis, and the biosensors involved. This fully updated new edition also includes new sections on viscous flows and centrifugal microfluidics, expanding the types of platforms covered to include centrifugal, capillary and electro kinetic platforms.

  • New Trends in Smart Nanostructured Biomaterials in Health Sciences

    • 1st Edition
    • Gil Goncalves + 2 more
    • English
    New Trends in Smart Nanostructured Biomaterials in Health Sciences provides guidance on the design and synthesis of nanostructured smart biomaterials, as well as the resultant therapeutic effects and associated biomedical applications of these novel materials. The book provides readers with a deeper understanding of these novel biomaterials and aids them in making informed decisions when selecting appropriate materials for tissue engineering and cancer therapy applications. It will be of specific interest to materials scientists, biomedical engineers, oncological scientists, tissue engineers and those working in regenerative medicine. Nanostructured smart materials have the special ability to respond to changes in the cell microenvironment, allowing for robust, biocompatible and rapidly adaptable, therapeutic and restorative action against a range of ailments. These materials are thus ideal candidates for use in tissue engineering and cancer therapy due to the varying nature of the cell microenvironment between persons, tissues and cancers. This book covers the design, synthesis, unique properties and application of smart biomaterials in these two key topic areas of tissue engineering and cancer therapeutics.

  • Atomic Clusters with Unusual Structure, Bonding and Reactivity

    Theoretical Approaches, Computational Assessment and Applications
    • 1st Edition
    • Pratim Kumar Chattaraj + 2 more
    • English
    Atomic Clusters with Unusual Structure, Bonding and Reactivity: Theoretical Approaches, Computational Assessment and Applications reviews the latest computational tools and approaches available for accurately assessing the properties of a cluster, while also highlighting how such clusters can be adapted and utilized for the development of novel materials and applications. Sections provide an introduction to the computational methods used to obtain global minima for clusters and effectively analyze bonds, outline experimental approaches to produce clusters, discuss specific applications, and explore cluster reactivity and usage across a number of fields.Drawing on the knowledge of its expert editors and contributors, this book provides a detailed guide to ascertaining the stability, bonding and properties of atomic clusters. Atomic clusters, which exhibit unusual properties, offer huge potential as building blocks for new materials and novel applications, but understanding their properties, stability and bonding is essential in order to accurately understand, characterize and manipulate them for further use. Searching for the most stable geometry of a given cluster is difficult and becomes even more so for clusters of medium and large sizes, where the number of possible isomers sharply increase, hence this book provides a unique and comprehensive approach to the topic and available techniques and applications.

  • Foundations of Maternal-Newborn and Women's Health Nursing

    • 8th Edition
    • Sharon Smith Murray + 4 more
    • English
    Make sure you fully understand how to care for women and newborns! Foundations of Maternal-Newborn and Women's Health Nursing, 8th Edition integrates essential maternity information into the overall continuum of nursing care to show you how to provide safe care in the clinical setting. With easy-to-understand language, this updated text uses evidence-based guidelines and step-by-step instructions for assessments and interventions to help you quickly master key skills and techniques. Also emphasized is the importance of understanding family, communication, culture, patient teaching, and clinical decision making.　Questions for the Next Generation NCLEX© in the text help you prepare for the exam.

  • Clinical Considerations in Child and Adolescent Mental Health with Diverse Populations, An Issue of Child And Adolescent Psychiatric Clinics of North America

    • 1st Edition
    • Volume 31-4
    • Warren Y.K. Ng + 2 more
    • English
    In this issue, guest editors bring their considerable expertise to this important topic.

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