The development of computational methods for the solution of scientific and engineering problems governed by the laws of mechanics was one of the great scientific and engineering achievements of the second half of the 20th century, with a profound impact on science and technology. This is accomplished through advanced mathematical modeling and numerical solutions reflecting a combination of concepts, methods and principles that are often interdisciplinary in nature and span several areas of mechanics, mathematics, computer science and other scientific disciplines as well. The continued staggering developments of the 21st century have now enabled simulation capabilities that are leading to tangible technological achievements for the clear betterment of mankind. Computer Methods in Applied Mechanics and Engineering was founded over five decades ago, providing a platform for the publication of papers in this important field of computational science and engineering. The range of appropriate contributions is very wide. It covers any type of computational method for the simulation of complex physical problems leading to the analysis and design of engineering products and systems.  This includes theoretical development and rational applications of mathematical models and numerical algorithms related to finite elements, boundary elements, finite differences, finite volumes, meshless discretization methods, isogeometric methods, molecular dynamics, ab-initio calculations, physically-based machine-learning methods and digital-twin technologies, in the following fields of simulation-based engineering science: Solid and structural mechanics Fluid mechanics Mechanics of materials Heat transfer Dynamics Geomechanics Acoustics Biomechanics NanomechanicsAtomist... Molecular dynamics Quantum mechanics Electromagneticsand also includes virtual design, multiscale phenomena, from nanoscale to macroscale, multiphysics problems, parallel computing, optimization, machine learning, probabilistic and stochastic approaches.CMAME publishes original papers at the forefront of modern research describing significant developments of computational methods in solving problems of applied mechanics and engineering.