The aim of the Journal is to provide a forum for the critical analysis of advanced drug and gene delivery systems and their applications in human and veterinary medicine. The Journal has a broad scope, covering the key issues for effective drug and gene delivery, from administration to site-specific delivery.In general, the Journal publishes review articles in a Theme Issue format. Each Theme Issue provides a comprehensive and critical examination of current and emerging research on the design and development of advanced drug and gene delivery systems and their application to experimental and clinical therapeutics. The goal is to illustrate the pivotal role of a multidisciplinary approach to modern drug delivery, encompassing the application of sound biological and physicochemical principles to the engineering of drug delivery systems to meet the therapeutic need at hand. Importantly the Editorial Team of ADDR asks that the authors effectively window the extensive volume of literature, pick the important contributions and explain their importance, produce a forward looking identification of the challenges facing the field and produce a Conclusions section with expert recommendations to address the issues.Articles review the current status of a specific topic, giving equal emphasis to the identification of major conceptual and technological challenges to successful drug and gene delivery, to an evaluation of triumphs as well as shortcomings in current conceptual and technical approaches, and to a discussion of their possible solution.Theme issues are commissioned by one of the Executive Editors or the Editor-in-Chief. The Journal does not publish stand alone manuscripts. If you wish to submit a theme issue topic for consideration, please contact one of the editors.Benefits to authors We also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services .Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our Support Center
A journal of nuclear and radiation techniques and their applications in the physical, chemical, biological, medical, earth, planetary, environmental, security and engineering science.Applied Radiation and Isotopes provides a high quality medium for the publication of substantial, original and scientific and technological papers on the development and peaceful application of nuclear, radiation and radionuclide techniques in chemistry, physics, biochemistry, biology, medicine, security, engineering and in the earth, planetary and environmental sciences, all including dosimetry. Nuclear techniques are defined in the broadest sense and both experimental and theoretical papers are welcome. They include the development and use of α- and β-particles, X-rays and γ-rays, neutrons and other nuclear particles and radiations from all sources, including radionuclides, synchrotron sources, cyclotrons and reactors and from the natural environment.The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria.Papers dealing with radiation processing, i.e., where radiation is used to bring about a biological, chemical or physical change in a material, should be directed to our sister journal Radiation Physics and Chemistry.Manuscripts describing the results of measurements of radioactive or other substances in any medium that have been obtained using well-established analytical methods will not be accepted unless they also describe substantial innovations or improvements in the analytical methodology. Relevant topics for Applied Radiation and Isotopes include the following, however, authors are encouraged to suggest other topics which might also be published in the journal:Radiation Sources: design, construction, production, characteristics.Radionuclides: production, activation cross-sections, target design, processing, quality control procedures.Synthesis of Labelled Compounds: synthesis, purification, quality control, in vitro testing of radionuclide-labelled compounds/ radiopharmaceuticals.Measurement of Radiation and Radioactivity: measurement of X-rays, γ-rays, α- and β-particles and other forms of radiation; nuclear instrumentation, including radiation spectrometry, dosimetry, novel counting systems and whole-body counters, novel radiation detector systems.Radioanalytical Methods: activation analysis, isotope dilution analysis, radioimmunoassay, radionuclide tomography, radiation spectrometry.Nuclear Physics and Chemistry topics including data compilations, directly relevant to practical applications.Nuclear Magnetic Resonance/Electron Spin Resonance: dosimetry, dating, imaging, biomedical applications and radiation accidents.Medical Radiation: the development of applications of ionising radiation and radioisotopes in radiation therapy, imaging and nuclear medicine.Accelerator Mass Spectrometry: methodology, biomedical, environmental and other applications.Nuclear Geophysics: studies of the earth's crust, the hydrosphere, the atmosphere and planetary bodies; nuclear methods for exploration, extraction, transport and use of water, oil, gas, coal and other minerals.Radiochemistry: chemical behaviour and speciation of radionuclides.Environment: chemical behaviour and speciation of radionuclides and labelled compounds other than those of direct clinical interest, in geological, environmental, human, animal or plant systems; factors which modify this behaviour.Manuscripts, which will be subject to peer review, should take one of the following forms:Full length articles, which should be definitive and describe a reasonably complete investigation.Short Communications, which may describe new, unpublished information, including preliminary communications and work in progress.Correspondence, containing comments related to articles previously published in the journal. This type of communication should not exceed two printed pages in order to expedite their publication.Review articles and conference proceedings may also be accepted for publication, following discussion with an editor of the journal.
Combinatorial chemistry is revolutionising the approach to synthetic organic chemistry and other fields, and is greatly enhancing the rate of discovery of new molecular entities.Combinatorial Chemistry - an Online Journal, is a unique WWW only publication, featuring papers accepted for publication in: Tetrahedron, Tetrahedron Letters, Tetrahedron: Asymmetry, Bioorganic & Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, Carbohydrate Research, and other relevant Elsevier journals. In addition it will feature links to articles from other publications.The journal is a free, monthly literature review. It does not accept unsolicited manuscripts.For further information, visit http://www.tetrahedron.info/cco tetrahedron.info
EJMECH (The European Journal of Medicinal Chemistry) is a global journal that publishes studies on the main aspects of medicinal chemistry. It provides a medium for publication of original research papers and it welcomes critical review papers.A typical paper would report on the design (with or without the support of computational methods), organic synthesis, characterization and biochemical/pharmacological evaluation of novel, potent compounds preferentially with a clear (or proven) mechanism of action and/or target. Other topics of interest are molecular aspects of drug metabolism, prodrug synthesis and drug targeting. The journal expects manuscripts to present a clear rational for a study, provide insight into the strategy and design of compounds and into the mechanism of action, and biological targets. Manuscripts reporting only computational studies are out-of-scope unless a new method (broadly applicable, validated and available to the community) is reported. Authors are kindly invited to look to published articles for the scope of the journal and the organisation of papers.
The Journal of Controlled Release (JCR) is the Official Journal of the Controlled Release Society, and of the Japan Society of Drug Delivery System.It publishes high-quality research articles in the broad field of delivery science and technology. This includes drug delivery systems and all aspects of formulations, such as physicochemical and biological properties of drugs, design and characterization of dosage forms, release mechanisms, in vivo testing, and formulation research and development in the disciplines of pharmaceutical, diagnostic, agricultural, environmental, cosmetic, and food industries.Manuscripts that advance fundamental understanding of principles and/or demonstrate advantages of novel technologies in safety and efficacy over current clinical standards will be given priority.
Laboratory Automation and Information Management aims to provide a vehicle for the publication of original research papers, short communications and tutorials on all aspects of these subjects. As such, it covers all of aspects of laboratory automation, information technology, storage, processing and data flows within a laboratory information environment within organisations.The journal deals with the following topics (this list is not exclusive): • Laboratory Information Management Systems (LIMS): systems architecture, database design, novel aspects of interfacing, methods of data acquisition and integration with other computer applications and instruments. • Means of integrating and merging laboratory information: final document preparation using chemical structures, spectra, results and text; corporate communication and use of laboratory information. • Networks: to link and integrate applications, novel technology for dissemination, storage and retrieval of information. • Standards: the emergence and development of standards for the capture, transmission and storage of laboratory data and information. • Electronic Laboratory Notebooks. • Human aspects of laboratory automation. • Regulatory aspects: development and implementation of governmental guidelines and regulations, and their effect on information management. • Robotics and laboratory automation: the application of robotics or dedicated automation systems is of interest where these systems are either stand alone applications or form an integrated solution for information management. The application of intelligent systems such as self optimising instruments or applications of expert systems or knowledge systems.The journal aims to cover any computer application and systems whether they have been designed in-house or are available commercially.The journal is directed to all scientists working in this highly disciplinary field: chemists, pharmaceutical scientists, computer scientists and engineers working in academic, clinical, industrial, and government laboratories.The journal publishes original research papers, tutorial articles (by invitation or by submission of an outline), critical reviews, short communications, case studies and software descriptions. A Monitor section provides news on meetings, book and software reviews, new commercial equipment and software relevant to the fields covered by the journal and a calendar of forthcoming events. Within the Monitor section there is the LIM interface. This allows less structured articles to be presented for open debate.
An International Journal devoted to their Science and TechnologyReactive & Functional Polymers provides a forum to disseminate original ideas, concepts and developments in the science and technology of polymers with functional groups, which impart specific chemical reactivity or physical, chemical, structural, biological, and pharmacological functionality. The scope covers organic polymers, acting for instance as reagents, catalysts, templates, ion-exchangers, selective sorbents, chelating or antimicrobial agents, drug carriers, sensors, membranes, and hydrogels. This also includes reactive cross-linkable prepolymers and high-performance thermosetting polymers, natural or degradable polymers, conducting polymers, and porous polymers.Original research articles must contain thorough molecular and material characterization data on synthesis of the above polymers in combination with their applications. Applications include but are not limited to catalysis, water or effluent treatment, separations and recovery, electronics and information storage, energy conversion, encapsulation, or adhesion.Full-length papers, perspectives and review articles will be considered. We welcome cutting-edge, original research within our scope. Modelling and simulation work will be considered only when linked to new or previously published experimental results. Lack of originality and novelty, insufficient molecular characterisation, or poor comparison with the current state of the art are reasons for rejection.