An international journal providing a forum for original and pertinent contributions in cancer researchCancer Letters is an international journal that considers full-length articles and Mini Reviews in the broad area of basic and translational oncology. Additionally, Special Issues highlight topical areas in cancer research. Basic areas of interest to a broad readership of Cancer Letters include the molecular genetics and cell biology of cancer, radiation biology, molecular pathology, hormones and cancer, viral oncology, metastasis, and chemoprevention. The journal places emphasis on experimental therapeutics, particularly targeted therapies for personalized cancer medicine, including metronomic chemotherapy.Benefits to authors We also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services.Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our support pages: https://service.elsevier.com.
DNA Repair (DNAREP) is a journal focusing on DNA repair and cellular responses to DNA damage. DNA Repair publishes articles on genetic, cellular, biochemical, structural and molecular aspects of DNA repair. The journal welcomes articles describing databases, methods and new technologies supporting research on DNA repair and responses to DNA damage. Letters to the Editor, hot topics and classics in DNA repair, historical reflections, book reviews and meeting reports will also be considered for publication.The journal publishes topics directly pertaining to DNA damage and repair, which include:ApoptosisBiological responses to genomic insultCell cycle regulationCell fate decisionsEpigenetics and chromatinGenomics/bioinformaticsHuman diseases: aging, cancer, and neurological dysfunctionImmune responsesMutagenesis & signature mutationsStructural biology and computational modeling
A section of Mutation ResearchMutation Research (MR) provides a platform for publishing all aspects of DNA mutations and epimutations, from basic evolutionary aspects to translational applications in genetic and epigenetic diagnostics and therapy. Mutations are defined as all possible alterations in DNA sequence and sequence organization, from point mutations to genome structural variation, chromosomal aberrations and aneuploidy. Epimutations are defined as alterations in the epigenome, i.e., changes in DNA methylation, histone modification and small regulatory RNAs.MR publishes articles in the following areas:Of special interest are basic mechanisms through which DNA damage and mutations impact development and differentiation, stem cell biology and cell fate in general, including various forms of cell death and cellular senescence.The study of genome instability in human molecular epidemiology and in relation to complex phenotypes, such as human disease, is considered a growing area of importance.Mechanisms of (epi)mutation induction, for example, during DNA repair, replication or recombination; novel methods of (epi)mutation detection, with a focus on ultra-high-throughput sequencing.Landscape of somatic mutations and epimutations in cancer and aging.Role of de novo mutations in human disease and aging; mutations in population genomics.Interactions between mutations and epimutations.The role of epimutations in chromatin structure and function.Mitochondrial DNA mutations and their consequences in terms of human disease and aging.Novel ways to generate mutations and epimutations in cell lines and animal models.MR supports and follows the general direction proposed by all major societies in the field part of the International Association of Environmental Mutagenesis and Genomics Societies (IAEMGS):Asociacion Latinoamericana de Mutagenesis, Carcinogenesis y Teratogenesis Ambiental (ALAMCTA)Brazilian Association of Mutagenesis and Environmental Genomics (MutaGen-Brasil)Chinese Environmental Mutagen Society (CEMS)European Environmental Mutagenesis and Genomics Society (EEMGS)Environmental Mutagenesis and Genomics Society (EMGS)Environmental Mutagen Society of India (EMS India)Iranian Environmental Mutagen Society (IrEMS)The Japanese Environmental Mutagen Society (JEMS)Korean Environmental Mutagen Society (KEMS)Molecular and Experimental Pathology Society of Australasia (MEPSA)Pan-African Environmental Mutagen Society (PAEMS)Philippines Environmental Mutagen Society (PEMS)Thai Environmental Mutagen Society (TEMS)Other Mutation Research sections: DNA Repair Mutation Research - Genetic Toxicology and Environmental Mutagenesis (MRGTEM) Mutation Research - Reviews (MRR)
A section of Mutation ResearchMutation Research: Genetic Toxicology and Environmental Mutagenesis (MRGTEM) publishes papers advancing knowledge in the field of genetic toxicology. Papers are welcomed in the following areas:New developments in genotoxicity testing of chemical agents (e.g., in methodology of assay systems and interpretation of results).Alternatives to and refinement of the use of animals in genotoxicity testing.Nano-genotoxicology, the study of genotoxicity hazards and risks related to novel man-made nanomaterials.Studies of epigenetic changes in relation to genotoxic effects.The use of structure-activity relationships in predicting genotoxic effects.The isolation and chemical characterization of novel environmental mutagens.The measurement of genotoxic effects in human populations, when accompanied by quantitative measurements of environmental or occupational exposures.The application of novel technologies for assessing the hazard and risks associated with genotoxic substances (e.g., OMICS or other high-throughput approaches to genotoxicity testing).Telomere biology as an endpoint for examination of the effects of chemicals and other environmental exposures.MRGTEM is now accepting submissions for a new section of the journal, "Current Topics in Genotoxicity Testing," that will be dedicated to the discussion of current issues relating to design, interpretation, and strategic use of genotoxicity tests. This section is envisaged to include discussions relating to the development of new international testing guidelines, but also to wider topics in the field. The evaluation of contrasting or opposing viewpoints is welcomed as long as the presentation is in accordance with the journal’s aims, scope, and policies.MRGTEM supports and follows the general direction proposed by all major societies in the field part of the International Association of Environmental Mutagenesis and Genomics Societies (IAEMGS):Asociacion Latinoamericana de Mutagenesis, Carcinogenesis y Teratogenesis Ambiental (ALAMCTA)Brazilian Association of Mutagenesis and Environmental Genomics (MutaGen-Brasil)Chinese Environmental Mutagen Society (CEMS)European Environmental Mutagenesis and Genomics Society (EEMGS)Environmental Mutagenesis and Genomics Society (EMGS)Environmental Mutagen Society of India (EMS India)Iranian Environmental Mutagen Society (IrEMS)The Japanese Environmental Mutagen Society (JEMS)Korean Environmental Mutagen Society (KEMS)Molecular and Experimental Pathology Society of Australasia (MEPSA)Pan-African Environmental Mutagen Society (PAEMS)Philippines Environmental Mutagen Society (PEMS)Thai Environmental Mutagen Society (TEMS)Other Mutation Research sections: DNA Repair Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis (MR) Mutation Research - Reviews (MRR)
The subject areas of Mutation Research - Reviews in Mutation Research (MRR) encompass the entire spectrum of the science of mutation research and its applications, with particular emphasis on the relationship between mutation and disease. Thus, this section will cover:Advances in human genome research (including evolving technologies for mutation detection and functional genomics) with applications in clinical genetics, gene therapy and health risk assessment for environmental agents of concernGenetic toxicology and environmental mutagenesis (including the factors that modulate the genetic activity of environmental agents) will continue to be prominent topics in this section.MRR supports and follows the general direction proposed by all major societies in the field part of the International Association of Environmental Mutagenesis and Genomics Societies (IAEMGS):Asociacion Latinoamericana de Mutagenesis, Carcinogenesis y Teratogenesis Ambiental (ALAMCTA)Brazilian Association of Mutagenesis and Environmental Genomics (MutaGen-Brasil)Chinese Environmental Mutagen Society (CEMS)European Environmental Mutagenesis and Genomics Society (EEMGS)Environmental Mutagenesis and Genomics Society (EMGS)Environmental Mutagen Society of India (EMS India)Iranian Environmental Mutagen Society (IrEMS)The Japanese Environmental Mutagen Society (JEMS)Korean Environmental Mutagen Society (KEMS)Molecular and Experimental Pathology Society of Australasia (MEPSA)Pan-African Environmental Mutagen Society (PAEMS)Philippines Environmental Mutagen Society (PEMS)Thai Environmental Mutagen Society (TEMS)Other Mutation Research sections: DNA Repair Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis (MR) Mutation Research - Genetic Toxicology and Environmental Mutagenesis (MRGTEM)