BBA Molecular Basis of Disease addresses the biochemistry and molecular genetics of disease processes and models of human disease. This journal covers aspects of aging, cancer, metabolic-, neurological-, and immunological-based disease. Manuscripts focused on using animal models to elucidate biochemical and mechanistic insight in each of these conditions, are particularly encouraged. Manuscripts should emphasize the underlying mechanisms of disease pathways and provide novel contributions to the understanding and/or treatment of these disorders. Highly descriptive and method development submissions may be declined without full review.Given the complex regulation of gene expression by a vast network of miRNA's, manuscripts describing the regulation of (disease-associated) genes by single miRNAs will only be considered if they provide genuine, novel insight in a disease mechanism. Further, studies restricted to a single cell line will not be considered unless they present truly novel insights.Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our Support Center
For more information go to http://www.cell.com/cell-systems Cell Systems was established in 2015 to provide a home at Cell Press for elegant work that addresses fundamental questions in systems biology. "Systems biology," as we broadly define it, is work that develops a rigorous understanding of any biological phenomenon where one plus one does not apparently equal two. Disciplines in the physical sciences have met this challenge for a long time, and we've found that our strongest papers tend to apply quantitative, inference-based approaches taken in physics, engineering, mathematics, and computer science to salient biological questions.We believe it's our responsibility to ensure that the next generation of scientists can begin their work on solid ground. Accordingly, we focus our review process on validity and scientific acuity, rather than more subjective feelings and opinions. We also believe that scientific transparency is of paramount importance. A study's structure and presentation should be candid and forthright (e.g. it should ensure fair comparisons; it should either use non-arbitrary cut-offs or clearly explained arbitrary cut-offs that do not affect outcomes; its data visualization choices should promote objective understanding; its limitations should not be obscured). Fundamentally good scientific practice also demands that studies be repeatable. We encourage authors to make their code and data FAIR?that is findable, accessible, interoperable, and reusable, as defined by the NIH data commons. Although it is too early to formally require that all studies we publish be FAIR, we consider that requirement annually.As editors, we hold ourselves to the same standards of transparency but also recognize that living up to those standards requires constant effort. Like all journals, Cell Systems is a work in progress. A collection of editorials that document our thoughts and their evolution can be found here. We are always happy to talk to you.Visit the Cell Press website for more information about Cell System- http://www.cell.com/cell-systems/home
Human Immunology publishes full-length, original, hypothesis-driven basic and clinical research articles as well as brief communications, reviews and editorials covering immunogenetics, transplantation immunology, autoimmunity, and immunity to infectious diseases in humans. It also publishes short population reports, which are tied to the allelefrequencies.net database, describing allele frequencies of HLA and KIR.The journal's scope includes understanding the genetic and functional mechanisms that distinguish human individuals in their immune responses to allografts, pregnancy, infections or vaccines as well as the immune responses that lead to autoimmunity, allergy or drug hypersensitivity. It also includes examining the distribution of the genes controlling these responses in populations.Research areas include: • Studies of the genetics, genomics, polymorphism, evolution, and population distribution of immune-related genes • Studies of the expression, structure and function of the products of immune-related genes • Immunogenetics of susceptibility to infectious and autoimmune disease, and allergy • The role of the immune-related genes in hematopoietic stem cell, solid organ, and vascularized composite allograft transplant • Histocompatibility studies including alloantibodies, epitope definition, and T cell alloreactivity • Studies of immunologic tolerance and pregnancy • T cell, B cell, NK and regulatory cell functions, particularly related to subjects within the journal's scope • Pharmacogenomics and vaccine development in the context of immune-related genesHuman Immunology considers immune-related genes to include those encoding classical and non-classical HLA, KIR, MIC, minor histocompatibility antigens (mHAg), immunoglobulins, TCR, BCR, proteins involved in antigen processing and presentation, complement, Fc receptors, chemokines and cytokines. Other immune-related genes may be considered.Human Immunology is also interested in bioinformatics of immune-related genes and organizational topics impacting laboratory processes, organ allocation, clinical strategies, and registries related to autoimmunity and transplantation.Original papers with new data will be given preference over uninvited reviews and meta- analyses.Original papers with new data will be given preference over uninvited reviews and meta- analyses. As the flagship scientific publication of the American Society for Histocompatibility and Immunogenetics (ASHI), Human Immunology is primarily directed to readers with an interest in histocompatibility, immunogenetics, transplantation, anthropology/population studies, HLA disease association and pharmacogenomics. These include basic and clinical scientists as well as histocompatibility laboratory professionals.
The Journal of Biotechnology (J. Biotech.) offers publication for both full-length articles and short communications on a wide range of biotechnology-related topics. Also, review articles can be submitted if they are pre-approved by one of the editors. The journal will only accept submissions with novel scientific research results that are directly relevant to biotechnological systems and/or applications (for details, please see the list below). J. Biotech. has strict rules about plagiarism. Any submission that includes parts of already published material will be rejected. This includes any attempt to re-publish already published Materials and Methods paragraphs. The journal features a "one-pass review process," i.e., eligible submissions will be reviewed, and those that need improvements (either minor or major) can be resubmitted only once before the decision about whether to accept or reject is decided by the Chief Editor. All figures need to be submitted as high-resolution files during the initial submission. All articles must be written in English, and the quality of the English language will be one of the criteria during the review process.Main Scope of the Journal:Bioprocess engineeringSystem biology, synthetic microbiologyMetabolic engineering, microbial physiologyBiorefinery, biomass engineeringBiochemical enzyme/protein engineeringMetabolic engineeringMicrobial expression systemsBiocatalyst engineeringInsect cell-based modelsMultienzyme cascade reactionsPlant-based biotechnologyOutside of the Scope:Manuscripts lacking noveltyReview articles submitted without previous invitation/confirmation by an editorEnvironmental-related subjects, e.g., waste-water treatment, bioremediation, biodegradationReports on the cloning and/or expression of naturally occurring enzymes without direct biotechnological applicationResearch on natural products without biotechnological modificationToxicological researchPharmacological researchFood science-related research without biotechnological applicationEngineering articles that do not deal with the direct improvement of biotechnological processesGenome research, especially genome sequencing reportsBenefits to authors We also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services.Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our Support Center
Official Journal of the Mitochondria Research Society Affiliated with the Japanese Society of Mitochondria Research and MedicineMitochondrion is a definitive, high profile, peer-reviewed international research journal. The scope of Mitochondrion is broad, reporting on basic science of mitochondria from all organisms and from basic research to pathology and clinical aspects of mitochondrial diseases. The journal welcomes original contributions from investigators working in diverse sub-disciplines such as evolution, biophysics, biochemistry, molecular and cell biology, genetics, pharmacology, toxicology, forensic science, programmed cell death, aging, cancer and clinical features of mitochondrial diseases.Mitochondrion includes: MitoMatters: Editorial and news of general interest invited by Editorial Office. Profiles and Perspectives: Invited by Editorial Office and written by senior investigators in the field. The Mito Mew: Editorial and news of general interest. Review Articles: Reviews of major importance in mitochondrial biology. These articles will be peer-reviewed. Articles may be of any length; however, unusually long articles should be discussed with the editor before submission. Fast Track Articles: Peer-reviewed, short studies that are refereed rapidly and published generally within 10 weeks. These papers should be a concise complete piece of work of special significance and timeliness and should not exceed 4 printed pages (i.e., 10 pages of double-spaced typescript, including tables and figures up to a total number of 4). Original Articles: Peer-reviewed, high-quality, concise research investigations that represent new and significant contributions to science. Letters to the Editor: Comments on papers published in the Journal and on other matters of interest to mitochondria researcher. Book Reviews: invited by the editorial office. Announcements and Calendar: Providing notices of forthcoming meetings, courses, and other events relevant to mitochondria researchers.
Molecular Therapy Molecular Therapy is the leading journal for research in the areas of gene transfer, vector development and design, stem cell manipulation, development of gene-, peptide-, protein-, oligonucleotide-, and cell-based therapeutics to correct genetic and acquired diseases, vaccine development, pre-clinical target validation, safety/efficacy studies, and clinical trials. Molecular Therapy is dedicated to promoting the sciences in genetics, medicine, and biotechnology. Publishing important peer-reviewed research and cutting-edge reviews and commentaries, the journal continues to attract the best material in the field. Molecular Therapy's 2022 impact factor is 12.4.Visit the Cell Press website for more information about Molecular Therapy - http://www.cell.com/molecular-therapy-family/home
This journal has no page charges, publication is free of charge.Papers published in the journal cover all aspects of microbial taxonomy, phylogeny, ecology, physiology and metabolism, molecular genetics and genomics, gene regulation, viruses of prokaryotes, as well as interactions between microbes or with their environment. Purely descriptive papers, as well as those which do not report significant advances in scientific research, are discouraged and may be rejected without review. Papers dealing with methods and theoretical microbiology may be published if they are associated with significant novel approaches and/or results. Papers on host-pathogen interactions, virulence and disease fall within the scope of the journal only if they cover the biology of the microbes.Currently, Research in Microbiology publishes the following types of papers:• Original articles: full-length research papers or brief notes • Reviews: generally commissioned, unsolicited reviews may also be considered. In this case, authors should contact the Editor-in-Chief. • Letters to the Editor: letters may be considered when a researcher wishes to comment on or respond to a published article. The Editor-in-Chief should be contacted for these or other types of contributions (news, book reviews, obituaries, etc.).Please also see: Research in Microbiology – Institut Pasteur