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Books in Organic chemistry

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Rearrangements with Migration to Electrophilic Heteroatomic Centers

  • 1st Edition
  • October 1, 2024
  • Sosale Chandrasekhar
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 3 7 4 3 - 4
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 3 7 4 4 - 1
Rearrangements with Migration to Electrophilic Heteroatomic Centers: Timeless Classics in Organic Synthesis covers the basic principles and synthetic applications of a critically important class of organic reactions that date back to the founding period of organic chemistry. These reactions are not only of historical and pedagogical interest, but also have great practical value to this day, being inevitable in any strategy concerning the introduction of nitrogen and oxygen functionality. The book is made up of three parts, dealing with the Beckmann reaction, the Hoffmann family of reactions and the Baeyer-Villiger reaction.The book strikes a balance between delineation and exhaustiveness, with up-to-date refences for readers requiring in-depth coverage. Relevant industrial applications, including pharmaceutical processes, are included.

Studies in Natural Products Chemistry

  • 1st Edition
  • Volume 83
  • October 1, 2024
  • Atta-ur Rahman
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 2 2 2 1 4 - 6
  • eBook
    9 7 8 - 0 - 4 4 3 - 2 2 2 1 5 - 3
Studies in Natural Products Chemistry, Volume 83 covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects.With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.

Advances in Prodrugs

  • 1st Edition
  • September 27, 2024
  • Claudiu Trandafir Supuran + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 5 6 3 5 - 9
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 6 3 4 - 2
Advances in Prodrugs: Design and Therapeutic Applications provides a versatile tool in prodrug design and development as well as a concrete perspective on clinical and preclinical studies currently available on prodrugs. The first part of this book discusses different chemical classes of prodrugs, with particular emphasis on metabolic pathways and mechanisms involved in the activation of their functional groups. The second part of the book covers therapeutic applications of prodrugs against the most discussed diseases, providing detailed discussion on recent achievements in the field. This book offers researchers involved in drug discovery key criteria for the successful development of prodrug-based therapeutic tools.Prodrugs are inactive drug precursors which undergo different chemical transformation by metabolic processes to provide pharmacologically active compounds. Prodrugs include a broad range of structurally diverse molecules employed for the treatment of several diseases.

Oxazole, Isoxazole, Benzoxazole-Based Drug Discovery

  • 1st Edition
  • September 16, 2024
  • Erum Akbar Hussain + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 8 5 3 8 6 - 6
Oxazole, Isoxazole, Benzoxazole Based Drug Discovery offers complete coverage of oxazole and related molecules, both from natural and synthetic origin, with a focus on the reaction mechanisms, and medicinal, pharmacokinetic and computational aspects. New and contemporary methods of synthesis are discussed, with a special focus on green, environment-friendly procedures. Discussion of stereochemical studies, particularly on natural molecules, are included. Computational chemistry has emerged as an integral tool for drug discovery, hence this book explains how the drug candidate is established as suitable for clinical trials with the help of molecular docking and virtual screening modeling.This book offers a broad range of recent developments and detailed coverage of synthesis and biological activities of the drugs, and is an ideal reference guide to researchers working in organic and medicinal chemistry.

The Alkaloids

  • 1st Edition
  • Volume 92
  • September 1, 2024
  • Hans-Joachim Knolker
  • English
  • Hardback
    9 7 8 - 0 - 4 4 3 - 2 9 7 4 4 - 1
  • eBook
    9 7 8 - 0 - 4 4 3 - 2 9 7 4 5 - 8
The Alkaloids: Chemistry and Biology, Volume 92, the newest release in a series that has covered the topic for more than 60 years, discusses key aspects of alkaloid chemistry, biology and pharmacology. Sections in this release include chapters on Renieramycin-type Bis-1,2,3,4-tetrahydroisoquinoline Marine Natural Products, Structure, activity, and biosynthesis of indolactam alkaloids, and The Chemistry and Biology of Pyrazole and Indazole Alkaloids.

Organic Synthesis

  • 5th Edition
  • August 13, 2024
  • Michael Smith
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 5 8 6 7 - 4
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 8 6 8 - 1
Organic Synthesis, Fifth Edition provides a reaction-based approach to this important branch of organic chemistry. Updated and accessible, this eagerly-awaited revision offers a comprehensive foundation for graduate students coming from disparate backgrounds and knowledge levels, providing them with critical working knowledge of basic reactions, stereochemistry, and conformational principles. This reliable resource uniquely incorporates molecular modeling content, problems, and visualizations, and includes reaction examples and homework problems drawn from the latest in the current literature.There have been advancements in organic reactions, particularly organometallic reactions, and there is a need to show how these advancements have influenced current organic synthesis. The goal is to revise and update the reaction examples taken from the synthesis literature from 2017 to 2023. The reactions illustrate those used most often in modern organic synthesis, but these new examples will show their current relevance. Where new approaches and reactions have been developed for organic synthesis, examples have been added as new material.

Visible Light-Driven Organic Synthesis

  • 1st Edition
  • August 9, 2024
  • Goutam Brahmachari
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 5 8 9 3 - 6
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 5 8 9 4 - 3
Visible Light-Driven Organic Synthesis covers the recent cutting-edge investigations in the field of visible light– driven organic synthesis in a single comprehensive volume. It provides information on rigorously selected reaction schemes and covers new reactions and new methods under visible light photocatalysis. It enlists more than 100 important synthetic strategies/methodologies with particular emphasis on useful reactions for organic synthesis under the mild reaction conditions reported in recent times involving carbon–carbon (C–C) and carbon–heteroatom bond–forming reactions, resulting in a wide spectrum of chemical compounds, providing an outstanding source of information concerning industrial applications.The chapters are classified based on various photocatalysts that have found direct applications in organic synthesis by carrying out different kinds of organic reactions. Each chapter is dedicated to a particular photocatalyst, and each selected reaction is dealt with in a compact manner through point-wise discussion under distinct subheadings covering the reaction type, reaction conditions, bond-forming information, reaction strategy involved, general reaction scheme, examples of representative entries with chemical structures and physical properties, a suggested plausible mechanism, critical views, and literature. In addition, visible light–mediated self-sensitized organic transformations that took place without any external photocatalysts have also been covered.This book is immensely helpful to chemistry students, teachers, researchers, academicians, and chemical/ agrochemical industry people to access the latest information and advances on visible light–driven organic synthesis developments.

Studies in Natural Products Chemistry

  • 1st Edition
  • Volume 82
  • July 24, 2024
  • Atta-Ur Rahman
  • English
  • Hardback
    9 7 8 - 0 - 4 4 3 - 1 5 7 5 6 - 1
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 7 5 7 - 8
Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.Studies in Natural Products Chemistry covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.

Advances in Organometallic Chemistry

  • 1st Edition
  • Volume 82
  • July 23, 2024
  • Pedro J. Perez
  • English
  • Hardback
    9 7 8 - 0 - 4 4 3 - 2 9 4 2 2 - 8
  • eBook
    9 7 8 - 0 - 4 4 3 - 2 9 4 2 3 - 5
Advances in Organometallic Chemistry, Volume 82, the latest release in this longstanding serial, is known for its comprehensive coverage of topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more. Chapters in this new release include Pd-catalysis: a useful tool in the field of polymer synthesis. Recent advances and applications, Modern Mechanistic Approaches for the Depolymerization of Commodity Plastics via Homogeneous Metal Catalysis, Functionalization of fullerenes by transition metal catalyzed cyclization reactions, and Synergistic Metal-Ligand Reactivity in Half-Sandwich Complexes of Fe, Co, and Ni for Bond Activation and Catalysis.

Specialized Plant Metabolites as Cosmeceuticals

  • 1st Edition
  • July 1, 2024
  • Deepika Kathuria + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 9 1 4 8 - 0
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 3 4 5 - 7
Specialized Plant Metabolites as Cosmeceuticals presents a comprehensive guide to traditional medicinal plants that are used in the field of cosmetics. Chapters cover geographical distribution, extraction of key components from each plant, traditional uses, pharmacognostic characteristics, phytochemistry, pharmacology, toxicology, and future prospects. This book will be a valuable asset for researchers and graduate students of chemistry, botany, biotechnology, microbiology, cosmetology and the pharmaceutical sciences. As medicinal plants are a rich source of a variety of bioactive secondary metabolites, their wide range of pharmacological applications as antibiotics, antifungals, anticancer agents, and antimicrobial and antiviral applications provide new and exciting avenues.In addition, they have great implications for the food, pharmaceutical, cosmetics and personal care product industries. Secondary metabolites also ecofriendly, cost effective, biocompatible, and cause less side effects as compare to synthetic compounds.