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Books in Medicinal chemistry

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71-80 of 110 results in All results

Progress in Medicinal Chemistry

  • 1st Edition
  • Volume 48
  • November 15, 2009
  • G. Lawton + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 5 3 3 5 8 - 6
  • eBook
    9 7 8 - 0 - 0 8 - 0 9 5 0 8 6 - 0
Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry. This volume continues in the serial's tradition of providing an insight into the skills required of the modern medicinal chemist; in particular, the use of an appropriate selection of the wide range of tools now available to solve key scientific problems.

Annual Reports in Medicinal Chemistry

  • 1st Edition
  • Volume 44
  • October 5, 2009
  • John E. Macor
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 3 7 4 7 6 6 - 2
  • eBook
    9 7 8 - 0 - 0 8 - 0 9 1 2 1 4 - 1
Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.

Progress in Medicinal Chemistry

  • 1st Edition
  • Volume 47
  • April 1, 2009
  • G. Lawton + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 5 3 3 0 0 - 5
  • eBook
    9 7 8 - 0 - 0 8 - 0 9 3 3 0 2 - 3
This volume provides reviews of six topics demonstrating the breadth of the field and recent successes in medicinal chemistry. Each of the first five chapters takes an important biochemical target as its theme and provides an insight into current progress in drug design. The last chapter focuses on the vital subject of pharmacokinetics and the great strides that have been made in this discipline during the past decade. All chapters provide an insight into the skills required of the modern medicinal chemist, in particular, the use of an appropriate selection of the wide range of tools now available to solve key scientific problems.

Annual Reports in Medicinal Chemistry

  • 1st Edition
  • Volume 43
  • October 20, 2008
  • John E. Macor
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 3 7 4 3 4 4 - 2
  • eBook
    9 7 8 - 0 - 0 8 - 0 9 2 1 8 7 - 7
Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.

Progress in Heterocyclic Chemistry

  • 1st Edition
  • Volume 20
  • September 26, 2008
  • Gordon Gribble + 1 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 9 1 4 9 5 - 4
This is the 20th annual volume of Progress in Heterocyclic Chemistry, which covers the literature published during 2007. As with previous volumes in the series, Volume 20 will enable the reader to keep abreast of developments in heterocyclic chemistry in an effortless way.

Progress in Medicinal Chemistry

  • 1st Edition
  • Volume 46
  • April 8, 2008
  • G. Lawton + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 5 3 0 1 8 - 9
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 6 9 6 8 - 0
Appropriate selection of biochemical targets is one of the most important drivers of cost effectiveness in the discovery of new medicines. Despite the many advances in genetics, genomics and systems biology, ‘validation’ of a target is not achieved until therapeutic efficacy is demonstrated by a drug candidate. Volume 46 of this series reviews the medicinal chemistry aimed at six diverse targets from which important new medicines are emerging: * HIV integrase (discovery of the first-in-class inhibitor drug raltegravir)* 11-beta-Hydroxysteroid dehydrogenase (new approach to glucocorticoid regulation)* Nicotinic a7 choline receptor (agonists and positive allosteric modulators). * Bradykinin receptor (new approach to pain therapy)* Histone deacetylase (new drugs for cancer)* 5-HT2c receptor modulators (various CNS indications)

Annual Reports in Medicinal Chemistry

  • 1st Edition
  • Volume 42
  • November 20, 2007
  • John E. Macor
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 3 7 3 9 1 2 - 4
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 5 4 8 7 - 7
Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.

Progress in Medicinal Chemistry

  • 1st Edition
  • Volume 45
  • February 19, 2007
  • F.D. King + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 5 2 8 0 8 - 7
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 7 1 3 1 - 0
The success of any drug discovery project relies upon the quality of the lead that initiates the lead optimization process. What defines a ‘quality lead’, where these ‘quality leads’ come from and how one discovers them has been the subject of intense debate within the pharmaceutical industry, relies upon defining those properties that historically have led to successful drug discovery. This volume addresses these questions and specifically discusses diabetes, obesity and tuberculosis.

Annual Reports in Medicinal Chemistry

  • 1st Edition
  • Volume 41
  • December 8, 2006
  • Anthony Wood
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 0 4 0 5 4 1 - 1
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 6 7 4 1 - 2
Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. Sections I-IV are disease orientated and generally report on specific medicinal agents. Sections V and VI continue to emphasize important topics in medicinal chemistry, biology, and drug design. Section VII looks at Trends and Perspectives in the pharmaceuticals market.

Progress in Medicinal Chemistry

  • 1st Edition
  • Volume 44
  • April 25, 2006
  • F.D. King + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 5 1 7 3 7 - 1
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 6 2 1 0 - 3
The perceived lack of drug discovery productivity in recent times has led to much debate in the pharmaceutical/biotechnology industry as escalating R&D costs are not being matched by increased output. Few observers doubt that selecting the right targets, ie those which are critical to disease pathology and are ‘druggable’, is the best starting point for improved productivity.The seven chapters of this volume describe recent progress towards drugs acting at a range of ‘druggable’ targets. One chapter addresses kinases, one covers an ion channel, two proteases are featured and three of the chapters cover G-protein coupled receptors, which has historically perhaps been the most fruitful area for medicinal chemists.