Advances in Protein Chemistry and Structural Biology, Volume 138 covers reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design. Chapters in this release include Proteomic Applications in Identifying Protein-Protein Interactions, Understanding functions of eEF1 translation elongation factors beyond translation. A proteomic approach, Proteomics provides insights into theranostic potential of extracellular vesicles, Towards a shareable functional analysis of the structural proteome, Functional unfoldomics, In-silico Network Pharmacology Study on Glycyrrhiza glabra: Analyzing the Immune-Boosting phytochemical properties of Siddha Medicinal Plant against COVID-19, and more.Other chapters cover In silico Network Pharmacology Analysis and Molecular Docking Validation of Swasa Kudori for Screening Druggable Phytoconstituents of Asthma, Proteomics and Genomics Insights on Malignant Osteosarcoma, Application of functional proteomics in understanding RNA Virus-Mediated Infection, Biofilm proteome of Staphylococcus aureus: implications for therapeutic interventions to biofilm-associated infections, A computational pipeline elucidating functions of conserved hypothetical Trypanosoma cruzi proteins based on public proteomic data, Functional Proteomics based on Protein Microarray Technology for Biomedical Research, and an Analysis of endoglucanases production using proteomics and metatranscriptomics.
Molecular Biology of B Cells, Third Edition provides a comprehensive reference on how B cells are generated, selected, activated, and engaged in antibody production. These developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. The book offers an integrated view of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. This new edition provides updated research on B cell development and function, the use of therapeutic antibodies in cancer and infectious disease, and more. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, this updated release is a definitive resource, vital for researchers across molecular biology, immunology, and genetics.
Targeting Angiogenesis, Inflammation and Oxidative Stress in Chronic Diseases presents recent advances in the vivid molecular pathways targeting angiogenesis, inflammation, and oxidative stress that contribute very widely to the genesis of chronic diseases. The books highlights drugs from natural and synthetic origins in the management/prevention/treatment of diseases, along with the drug delivery approaches. The book’s authors from various key institutions around the globe deliver well-structured and designed chapters. The systematic presented information and knowledge will surely aid consistency and continuity. The multifaceted book is enriched with deep scientific content. Each chapter clearly defines the facts, the emerging role of molecular pathways, and targets and focus, along with key challenges and future directions that will provide new areas for researchers to explore new targets in the domain.
Advances in Agronomy, Volume 183, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field. Each chapter is written by an international board of authors, with this new release offering the latest on Soil Security – Strategizing a Sustainable Future for Soil, Reflection on a Career as a Soil Scientist in the Middle East, Biodegradable Plastics as Alternatives for Polyethylene Mulch Films, Biosensing Technology Interventions for the Detection of Nitrate and Nitrite Contamination in Environment and Foods, and Microbial Fertilization as a Preferable Choice than Synthetic Chemical Fertilization in Modern Farming.
The Potential of Microbes for a Circular Economy provides an understanding of the role of microbes in a circular economy (CE). The book covers the development of effective bio-based formulations for field applications and describes the basic principles and applications, the important role of microorganisms, and new insights into a sustainable ecosystem for the circular economy. In addition, it compiles the latest advancement in the field of CE by covering microbes and microbial products, thus providing microbiologists the tools to engage with the public, policymakers, and industry to inform the debate on addressing current challenges.
Continental Northeast Asian Amphibians: Origins, Behavioral Ecology, and Conservation is the only comprehensive compilation of knowledge on the amphibian species of continental northeast Asia. Along with accounts for each species, the book introduces the biogeographic history, behavioral patterns, ecological requirements, and threats in the region. Written by a leading expert on Asian amphibians, this book delves into the details of origin and life history and distinguishes which variables have been instrumental to the distribution of populations and amphibian biodiversity in this region. Sections provide detailed accounts for field identification and range of the species’ behavior during both breeding and non-breeding seasons.Finally, the book provides in-depth accounts on the threats and trends for each species, considering the current conservation pressure in the region. Each point is explained in relation with the very contrasted landscapes of the region that include two rather different species assemblages, one on the alluvial plains and the other at higher elevation on mountain ranges.
Succinct yet comprehensive, Aminoff's Diagnosis of Neuromuscular Disorders, 4th Edition, provides expert information and guidance on the clinical, electrodiagnostic, and imaging aspects of neuromuscular disorders. Fully updated, it reflects important advances in the field, including an improved understanding of the molecular and genetic basis of neuromuscular disease, an expanded use of next-generation genetic testing, refinements in electrodiagnosis, and the use of ultrasound imaging techniques to evaluate the peripheral nervous system. In-depth discussions of disease states, as well as the evidence supporting the use of electrodiagnostic and imaging techniques, moves this reference from simply answering the question “How?” to also answering “Why?”
Clinical Aspects of Multiple Sclerosis Essentials and Current Updates offers readers a comprehensive and up-to-date analysis of multiple sclerosis (MS) and its related disorders, providing the latest research findings and insights to ensure readers are well informed. This book thoroughly examines the underlying genetic factors contributing to the development of the disease while emphasizing the significant role of vitamin D in both the pathogenesis and treatment of MS. Furthermore, this book provides essential information on current treatment guidelines for effectively managing MS during pregnancy. This includes a specific focus on optimizing outcomes and addressing the complexities involved, healthcare professionals are equipped to handle the challenges presented by this specific patient population. Overall, this book delivers meticulous, updated, and extensive information on all aspects of MS, from demographic features and etiopathogenesis to the latest diagnostic and therapeutic interventions. With a focus on delivering valuable knowledge and practical insights, Clinical Aspects of Multiple Sclerosis Essentials and Current Updates serves as an essential resource for healthcare professionals and researchers seeking a deeper understanding of MS.
Immunobiology of COVID19, Volume 202 in the Progress in Molecular Biology and Translational Science Series provides a comprehensive and in-depth exploration of the SARS-CoV-2 virus and its impact on human health. Written by a team of expert contributors, the book covers various aspects of the virus, including its structure, lifecycle, and genomic replication. It delves into the epidemiology of COVID-19, comparing it with other related coronaviruses and discussing the concept of herd immunity. The structural biology of SARS-CoV-2 is examined, with a focus on techniques such as electron microscopy and cryo-electron tomography. The book also explores the biology of SARS-CoV-2 variants and their immune evasion strategies. Furthermore, it delves into the pathogenesis of COVID-19, examining its multiorgan manifestations and the long-term effects of the disease. The innate and adaptive immune responses to SARS-CoV-2 are discussed in detail, along with the role of B cells and T cells in the immune response. The volume concludes with a look at future insights and potential developments in the field. Accompanied by illustrative diagrams and visuals, this volume will serve as a valuable resource for researchers, healthcare professionals, and anyone interested in understanding the intricate details of SARS-CoV-2 and its impact on global health.
Immune Checkpoint Biology in Health and Disease, Volume 382 provides in-depth reviews on the latest progress concerning research on immune-checkpoint biology and its immunotherapeutic implications, especially in cancer. Topics connected to immune-checkpoint biology covered in this volume include Novel technologies for applying immune checkpoint blockers, Next-generation deconvolution of transcriptomic data to investigate the tumor microenvironment, Immune checkpoints targeting dendritic cells for antibody-based modulation in cancer, Immune checkpoint biology in health & disease: Immune checkpoint biology and autoimmunity in cancer patients, and much more.Other sections cover Recent advancements in tumor microenvironment landscaping for target selection and response prediction in immune checkpoint therapies achieved through spatial protein multiplexing analysis, Immune Modulation During Anti-Cancer Radio(immuno)therapy, and Preconditioning with immunogenic cell death-inducing treatments for subsequent immunotherapy.