Unveiling the Proteolytic Networks of Parasites, Volume 128 presents a cutting-edge exploration of specific proteases across a spectrum of parasitic organisms. Top researchers in the field conduct multifaceted examinations, shedding light on the distinct roles of these proteases within significant parasite groups, including malaria, trematodes, nematodes, and blood-feeding arthropods. Chapters in this new release include Bioinformatic analysis of proteases across multiple helminth species: a case study using Wormbase, UniProt and Merops databases, Proteasomes of parasites, Proteases of Trematodes as a promising drug targets-tentative title, Astacins, and metalloproteases in nematodes, and Proteases of bloodfeeding arthropods.
An Illustrated Guide to Cancer Biology offers a comprehensive exploration of the fundamentals of oncological molecular biology and provides valuable insights into topics such as cancer cell migration, chemotherapeutic drug mechanisms, and the roles of RNA in cancer. With 33 chapters covering a wide array of subjects, including the Hanahan and Weinberg hallmarks of cancer, tumor heterogeneity, and hormone-dependent cancer, this guide serves as an indispensable resource for researchers, students, and practicing oncologists in medicine, oncology, and biochemistry alike. This book stands out not only for its comprehensive coverage of diverse topics but also for its unique approach to enhancing understanding through visual aids. With over 400 figures strategically interspersed throughout the text, this book offers readers a visually engaging journey through the intricacies of cancer biology. These illustrations, ranging from molecular pathways to cellular interactions, make navigating topics like chemotherapeutic drug mechanisms and tumor heterogeneity more accessible. Additionally, the inclusion of sections on repurposing drugs, tumor kinetics, and epigenetics further aids in a deep understanding of cancer biology. Through clear illustrations and accessible language, "An Illustrated Guide to Cancer Biology" empowers its audience to navigate the complexities of cancer research and treatment with confidence and insight.
Explore the revolutionary intersection of nanotechnology and dermatology in Nanodermatology: Advances in Theory and Practice. This comprehensive reference navigates the evolving landscape of skincare, offering a deep dive into the principles, innovations, and practical implications of nanotechnology in dermatological research and practice. This book addresses both basic and clinical aspects and conveys practical insights needed to navigate the complexities of nanodermatology through applied case studies, real-world examples, and actionable recommendations. From fundamental principles to diagnostic techniques, therapeutic interventions, safety considerations, ethics, and regulation, it offers practical insights for advancing nanodermatology research and application. Additionally, the inclusion of clinical uses and regulatory considerations ensures that the book offers functional guidance for translating nanodermatology research into clinical practice. From enhancing drug delivery systems to advancing cosmetic formulations, this authoritative guide illuminates the cutting-edge advancements shaping the future of skincare, making it an indispensable resource for researchers, clinicians, and students alike.
Sports Physician Handbook, the fourth edition of Team Physician Manual: International Federation of Sports Medicine (FIMS), covers all key area of activity and intervention, from the preparticipation examination to rehabilitation, drug testing, young athlete, female athlete and even environmental issues. The book also surveys the most significant classifications of sports injury, offering clear advice on fieldside assessment, diagnosis and treatment, as well as examining best practice in general aspects of sports medicine, such as prevention and the psychology of injury. Sports Physician Handbook continues the high caliber of authorship from a team of world-leading physicians and scientists from around the world. In short, the fourth edition represents a ‘must have’ reference for any doctor, scientists, physical therapist, or medical professional working in sport.
Keys to Afrotropical Fauna, Volume Seven in Thorp and Covich’s Freshwater Invertebrates series, provides the gold standard for books on aquatic invertebrates of Africa. It is the primary source for applied and basic studies of inland water invertebrates of Africa, whether the user is focused on human health (disease vectors), aquaculture, or general ecology and systematics. This text can be used by scientists from many countries and continents who are studying aquatic fauna in Africa, as well as by teachers and students in academia and employees in government agencies in many African countries.Each book of the series is developed to be the most modern and consistent set of taxonomic keys on the region. The design of the series provides a highly comprehensive, current set of keys in one place for each of these bioregions, with all keys written in a consistent style. This book is essential for anyone working in water quality management, conservation, ecology or related fields in these regions.
Targeted Protein Degradation Technologies provides a thorough overview of targeted protein degradation from the latest developments in the field to potential therapeutic applications. The book begins with an introduction to the mechanisms of protein degradation followed by a section covering both protease-mediate degradation and lysosome-mediate degradation. A range of cutting-edge technologies are covered, including PROTAC, AbTAC, molecular glues, hydrophobic tagging, LYTAC, GlueTAC and AUTAC. Degraders of specific proteins are then investigated, including signal transduction receptors, membrane proteins, and transcription factor degraders.The book closes with a section on the clinical applications of targeted protein degradation and a look at future perspectives. It is a useful resource to those in the fields of molecular biology, cell biology, and related areas working with protein degradation and the development of therapeutic technologies in this arena.
Transforming Healthcare Using Artificial Intelligence provides insights executing healthcare transformation through artificial intelligence, deploying health technology at scale, technology research, development and adoption and, interactions with leading clinicians and healthcare administrators from around the world. With a strong focus on what is most needed to transform healthcare systems to improve patient outcomes while managing costs, and how selected use of artificial intelligence can dovetail with those needs, this book also contrast this with a “tech push” approach where innovations are made, and it is then seen how they might be used in the practice of healthcare. In 14 chapters "Transforming Healthcare Using Artificial Intelligence" lays out the most urgent challenges facing both the patient and the provider. For patients, these include patient lifestyle, patient self-empowerment, adherence, knowledge, and behaviour change. Meanwhile, for clinicians the challenges are information overload, time scarcity, rapidly changing guidelines and care protocols, care quality, as well as “feeding the beast” of EMRs and insurance documentation It explains recent AI breakthroughs and then critically evaluates the promise of AI and shows how it can be selectively and successfully deployed to alleviate these challenges. Illustrations are drawn from real deployments and scaling, and rigorous experimentation and evidence-gathering throws light on the best bets for AI in Healthcare. While innovation in this field is moving very fast, adoption is appropriately slowed by the need for assurances of patient safety, clinical trials and, in some cases, regulatory approvals. This book is a valuable resource for health professionals, scientists and researchers, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.
Handbook of Hygiene Control in the Food Industry, Third Edition provides a comprehensive accounting of risk analysis and management solutions to minimize risks and hazards in the food industry, guiding professionals and students towards a safe food supply, from farm to fork. It is completely updated to address new issues and concerns while also addressing the latest technologies. This book continues to be an authoritative reference for anyone in the food industry who needs to have hands-on practical information to improve best practices to further food safety and quality.It is written by leaders in the field who understand the complex issues of control surrounding food industry design, operations, and processes, contamination management methods, route analysis processing, as well as allergenic residues, pest management and more. The book