Nearly all orthopaedic surgeons have implanted a cobalt-chromium hip, and most general practitioners have at least one patient with a cobalt-chromium prosthesis on their books. The recent worldwide controversy surrounding metal-on-metal bearings – and increasing concern over the use of metallic biomaterials in general – means that advice on how to manage patients with metal implants is of great interest to these professionals. Specifically, they want to know if there are any diagnostic tests that could be performed to gain clues about implant performance and the risk of local or systemic toxicity. Biomarkers of Hip Implant Function aims to bring together all established and promising new biomarkers and critically evaluate their clinical usefulness. Researchers will benefit from an updated, comprehensive view of the topic to identify underexplored areas. Orthopaedic surgeons and general practitioners will use the book to monitor implant performance and manage their patients. The work may also benefit engineers and joint implant manufacturers by guiding improvements in implant design, and be of interest to regulators and policymakers to inform guidelines on the follow-up of hip implant recipients.Â
Encyclopedia of Sleep and Circadian Rhythms, Second Edition, Six Volume Set is the most comprehensive work on sleep and circadian rhythms. This completely revised new edition, comprised of contributions from 450 renowned authorities in the field, covers what is new and known in the field. In addition to thorough coverage of the basics (physiology, sleep disorders etc.), this new edition includes a thorough examination of circadian rhythms that manage the sleep-wake cycle. Although this area is highly intertwined with sleep, it is a scientific discipline in and of itself, and will broaden the appeal of this work to health care providers and scientists. Other sections of interest explore consumer wearable devices to track sleep and circadian rhythms, artificial intelligence algorithms to detect sleep and abnormal sleep-related conditions, and new technology to treat sleep and circadian rhythm disorders. This book will be an ideal and primary reference resource for students, trainees, technologists, basic/clinical scientists, physicians, advanced practice providers, psychologists, nurses, and other medical and research personnel who want to explore any topic within the sleep and circadian rhythm field.
Nanotechnology for Drug Delivery and Pharmaceutical Sciences presents various drug-delivery techniques that utilize nanotechnology for the biomedical domain, highlighting both therapeutic and diagnostic applications. The book provides important facts and detailed studies on different promising nanocarriers like liposomes, exosomes and virus-based nanocarriers. Moreover, it explores these nanocarriers' utilization in the therapeutic applications of various diseases such as cancer, inflammation, neurodegenerative disorders like Huntington’s disease, Alzheimer's disease, human immunodeficiency virus (HIV), and inflammatory bowel disease. In addition, the book describes how nanotechnology has efficiently overtaken conventional dosage forms and provided comfort and ease to patients. Relevant information regarding market trends, patents and social-economic factors are also provided, making this the perfect reference for doctors, researchers and scientists working in the fields of medicine, biochemistry, biotechnology, nanobiotechnology and the pharmaceutical sciences.
Advances in Agronomy, Volume 117, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field. Chapters in this new release include Farming Systems Research: Concepts, Design and Methodology, Soil Potassium Fertility and Management Strategies in South Asian Agriculture, Sensing for Characterizing and Monitoring Soil Functions – A Review, Isolation and Fractionation of Organic Matter from Soils and Waters, Tolerance Mechanism and Management Concepts of Iron Toxicity in Rice: A Critical Review, and Smart Sensing and Automated Irrigation for Sustainable Rice Systems: A State of the Art Review.
Receptor Endocytosis and Signalling in Health and Disease, Volume 194 in the Progress in Molecular Biology and Translational Science, highlights new advances in the field. Chapters in this release include An overview on receptor endocytosis and signaling, Signaling molecules: Importance in health and disease conditions, Emerging tools for studying of receptor endocytosis and signaling, Endocytosis of EGFR: Signalling in cancer, Endocytosis of AT1 and AT2 receptors: Signalling in the kidney, Regulation of transferrin receptor trafficking by optineurin and its disease-associated mutants, Endocytosis of Insulin receptor: Signalling in the regulation of glucose homeostasis, Endocytosis of VEGFR: Role in the regulation of angiogenesis, and more. Other sections in this new release include Lymphocyte and monocyte/macrophage receptors mediating immune recognition of tumors, Lymphocyte and monocyte/macrophage receptors triggering immune suppression of tumor immunity, Prion receptors and prion internalization and intra- and inter-cellular transport, Multifunctional role of the ubiquitin proteasome pathway in phagocytosis, Adrenoceptors and SCD1 in adipocytes/adipose tissues: the expression and variation in health and obesity, Frizzled receptors and SFRP5 in lipid metabolism: current findings and potential applications.
Ticks: Biology, Ecology and Diseases provides a detailed overview of the fascinating world of tick biology and ecology. This book discusses disease transmission to humans and livestock, assesses the impact of human behavior and climate change on tick biology, and details how this will affect future disease transmission. Written by an expert on ticks and their transmitted diseases, this book explores the unique biology of ticks and how it influences the transmission of some of the most devastating diseases. In a series of detailed chapters, the book provides up-to-date information on the interrelationship between ticks and the vertebrates they feed on. In addition, the book covers information on recent scientific discoveries surrounding ticks, along with reviews on control methods and disease transmission. Other sections cover the recent emergence of tick-borne pathogens, making this book an ideal source for interested scientists, clinicians, veterinarians and experts in the field of tick biology.
Biosurfactants: Research and Development provides a thorough overview of biosurfactant research and development across a range of settings and industries, highlighting the novel use of enzymes, metabolic and genetic engineering in biosurfactant production and showcasing diverse experimental models and approaches. Sections discuss fundamental characteristics of biosurfactants, their physio-chemical properties, and their differences from chemically synthesize surfactants, different research approaches for the study of known biosurfactants, and the genetic manipulation of microorganisms to increase biosurfactant productivity, or to produce molecules with improved characteristics. Throughout the book, methods and approaches are discussed in easy-to-digest formats, with methods discussed, ranging from in silico approaches to classical biocatalysis omics analysis and metabolic engineering.
Smartphone Apps for Health and Wellness helps readers navigate the world of smartphone apps to direct them to those which have had the best medical evidence in obtaining the users’ goal. The book covers the history of apps, how they work, and specific apps to improve health and wellness in order to improve patients outcomes. It discusses several types of apps, including apps for medical care, sleeping, relaxation, nutrition, exercise and weight loss. In addition, sections present the features of a good app to empower readers to make their own decision when evaluating which one to use. This is a valuable resource for clinicians, physicians, researchers and members of biomedical field who are interested in taking advantage of smartphone apps to improve overall health and wellness of patients.
Advances in Epidemiological Modeling and Control of Viruses covers recent and advanced research works in the field of epidemiological modeling, with special emphasis on new strategies to control the occurrence and reoccurrence of viruses. The models included in this book can be used to study the dynamics of different viruses, searching for control measures, and epidemic models under various effects and environments. This book covers different models and methods of modeling, including data-driven approaches. The authors and editors are experienced researchers, and each chapter has been designed to provide readers with leading-edge information on topics discussed.
Dysphagia: Diagnosis and Treatment of Esophageal Motility Disorders provides a interdisciplinary overview of the diagnosis and management of dysphagia and other esophageal symptoms. All aspects of dysphagia are covered, with detailed consideration of both physiology and evaluation methods. Hot topics include coverage on the pharmacological causes of dysphagia, the physiology of normal swallowing, ambulatory pH monitoring as well as recurrent dysphagia after treatments. The content is grounded in evidence-based medicine that is the result of clinical outcome research, both prospective and randomized, making this the perfect reference for clinical researchers and a go-to for general surgeons, foreguts surgeons, thoracic surgeons and gastroenterologists.