Books in Life sciences

Neurophysiology of Silence Part A: Empirical Studies

1st Edition
Volume 277
June 6, 2023
Tal Dotan Ben-Soussan + 2 more
English
Hardback
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eBook
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Neurophysiology of Silence, Volume 277 in the Progress in Brain Research series, highlights new advances in the field, including chapters on Mindfulness, mind wandering and creativity, The cloud of unknowing: Cognitive dedifferentiation in whole-body perceptual deprivation, Embodying abstract concepts: the connection between meditation, empathy and introception, Measures of music-like experience emergent in a sonic ganzfeld: an example of perceptual structuring on the edge of silence, Doing out of silence: The effects of visual art on verbal creativity, Cessation experiences during meditation, The psychophysiology of covert behavior during goal directed behavior, and much more.

Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders

1st Edition
June 6, 2023
Heba Mohamed Mansour + 2 more
English
Paperback
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eBook
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Overexpression of receptor tyrosine kinases (RTKs) has been implicated in cancer. Increasing evidence suggests that dysregulation of RTKs is reported in many neurodegenerative and psychiatric disorders. Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders provides a fundamental, pragmatic map of RTKs structure, activation, functions, mechanism of action, gene regulation, and signaling pathways in developing central nervous system (CNS), adult normal CNS, neurodegenerative and psychiatric disorders. Additionally, the structure, function, activation, and therapeutic potential of many growth factors have been covered. Here, international experts in the field offer a comprehensive discussion of results of pre-clinical and clinical studies of repositioning of anti-cancer receptor tyrosine kinase inhibitors (RTKIs) and other promising protein kinase inhibitors in various neurodegenerative disorders including, Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis, and psychiatric disorders including, anxiety, depression, alcohol use disorder, and schizophrenia. In addition, the book discusses the obstacles and opportunities for the potential repositioning of kinase inhibitors in neurodegenerative and psychiatric disorders.

Cases in Laboratory Genetics and Genomics (LGG) Practice

1st Edition
June 5, 2023
Xia Li
English
Paperback
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eBook
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Cases in Laboratory Genetics and Genomics (LGG) Practice instructs readers in the lab-based diagnosis of genetic conditions, including inborn and acquired disorders using cytogenetics and molecular genetics technologies. This entirely case-based book covers a wide range of genetic cases, from prenatal to postnatal and oncology genetic disorders which lab professionals and geneticists encounter daily in the diagnostic field. Each disorder discussed includes a section on clinical background, clinical indication, tests ordered, laboratory tests performed, test results, results with interpretations, future testing and recommendations, and references. The book will help lab professionals understand and navigate clinical cases using an integrative approach, and thoroughly understand the methodologies and interpretations involved in high complexity genetic testing.

Cannabis Use, Neurobiology, Psychology, and Treatment

1st Edition
June 2, 2023
Colin R. Martin + 2 more
English
Hardback
9 7 8 0 3 2 3 8 9 8 6 2 1
eBook
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Cannabis Use, Neurobiology, Psychology, and Treatment offers readers a comprehensive reference on neurological changes, both transient and long-term, and other factors surrounding the use of these compounds and extracts. With coverage of both natural and synthetic cannabinoids, this broad coverage allows readers to learn about both adverse and non-adverse effects, including reactivity to pain, changes in behavior, and neuroactivity. This volume provides a platform for research on the effects of these compounds in brain function and neurological dysfunction. Extracts from the Cannabis sativa plant contain scores of psychoactive compounds in addition to the principal agent tetrahydrocannabinol... many of which are neuroactive.

Medicinal Usage of Cannabis and Cannabinoids

1st Edition
June 2, 2023
Victor R Preedy + 2 more
English
Hardback
9 7 8 0 3 2 3 9 0 0 3 6 2
eBook
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There is a growing body of data supporting the usage of cannabis and cannabis-related products in alleviating or preventing symptoms in different diseases and conditions. Medicinal Usage of Cannabis and Cannabinoids offers readers a comprehensive reference on the medical usage and symptom relief provided by these compounds in a variety of disorders. With coverage of neurological diseases like Alzheimer’s and Parkinson’s, and a wide range of other afflictions including depression, anxiety, nausea, and cancer, this broad coverage allows readers to learn about symptom control but also physiological, psychological, and pharmacological effects of these compounds. Unique case reports are provided as well. This volume provides a platform for research on the use of these compounds in improving patient care, brain function, and neurological dysfunction.

Neurobiology and Physiology of the Endocannabinoid System

1st Edition
June 2, 2023
Vinood B. Patel + 2 more
English
Hardback
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eBook
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Neurobiology and Physiology of the Endocannabinoid System offers readers a comprehensive reference on the neurobiology of this system and the use of cannabimimetic compounds to induce neurological changes and confer symptom relief. With sections on both natural and synthetic compounds, the book's broad coverage allows readers to learn about their use with multiple conditions, as well as the working biology of the endocannabinoid system, its receptors and its ligands. This volume provides a platform for research on the effects of this system and its modulation in brain function and neurological dysfunction.

Ozone Pollution and Plant Health: Understanding the Impacts and Solutions for Sustainable Agriculture

1st Edition
Volume 108
June 1, 2023
Felix Leung
English
Hardback
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eBook
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Advances in Botanical Research Volume 108: Ozone Pollution and Plant Health: Understanding the Impacts and Solutions for Sustainable Agriculture provides a comprehensive overview of the harmful effects of tropospheric ozone (O3) pollution on crop productivity, with a focus on how it is measured and modeled under climate change scenarios. The book discusses the sources of O3 pollution, including anthropogenic precursor gases, and how O3 exposure can impair photosynthesis, reduce gas exchange, induce early leaf senescence, and hamper growth in natural vegetation and crops. The book highlights how O3 interacts with plant physiology and metabolism, including through the activation of signal transduction pathways, changes in phytohormone signaling, and modulation of reactive oxygen species (ROS) generation and signaling. The book also explores the experimental and modeling methods used to assess the effects of O3 on crops, with a focus on studies conducted in Asia. The book emphasizes the importance of understanding the implications of ozone pollution for ensuring food security and protecting human and environmental health and suggests strategies such as using ozone-resistant cultivars of plants and crops. Additionally, the book discusses the broader context of air pollution and its impact on crop productivity, including the effects of other air pollutants on plants and crops and the need for mitigation strategies and policies to address agricultural losses. This book is essential reading for early-career researchers, sustainable agriculture practitioners, and policymakers interested in understanding the complex interactions between ozone pollution and plant productivity and finding solutions to mitigate the detrimental effects of ozone pollution on crops in a changing climate.

Advances in Clinical Chemistry

1st Edition
Volume 114
June 1, 2023
Gregory S. Makowski
English
Hardback
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eBook
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Advances in Clinical Chemistry, Volume 114, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. New sections in the updated release include Growth differentiation factor 15 (GDF-15) in kidney diseases, Alkaptonuria - past, present and future, Alcohol Consumption and Nutritional Biomarkers in Early-Stage Alcohol-Associated Liver Disease, Advances in Liquid Biopsy–Based Markers in NSCLC, D-dimer testing: a narrative review, Evolving Markers in Amyotrophic Lateral Sclerosis, and more.

Opioids

1st Edition
Volume 4
May 31, 2023
George F. Koob + 3 more
English
Paperback
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eBook
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A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Opioids, Volume 4 in the series, explores the molecular, cellular and systems in the brain responsible for opioid addiction using the heuristic three-stage cycle framework of binge/intoxication, withdrawal/negative affect, and preoccupation/antici...

Pancreatic Cancer: Basic Mechanisms and Therapies

1st Edition
Volume 159
May 31, 2023
Luni Emdad + 4 more
English
Hardback
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eBook
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Pancreatic Cancer: Basic Mechanisms and Therapies, Volume 159 in the Advances in Cancer Research, presents the latest release in this ongoing, well-regarded serial with invaluable information on the exciting and fast-moving field of cancer research. Pancreatic cancer (PC) is the third leading cause of cancer-related deaths in the United States. Greater than 90% PCs are Pancreatic ductal adenocarcinomas (PDAC) which have a dismal estimated 5-year overall survival of only 11%. PDAC is predicted to become the second leading cause of mortality in the United States by 2030. In the clinic, the PDAC patients often present with incurable disease at the time of first diagnosis. This cancer is particularly lethal because of its propensity to spread quickly to distant organs including the lymphatic system. PDAC metastasis occurs shortly after tumor initiation and is caused by a complex interaction between autonomous tumor cells and cellular elements of the tumor microenvironment. Although PDAC remains a challenging disease to treat and a leading cause of cancer-related deaths, progress is being made in disease etiology and pathogenesis, and intensive research is focused on developing optimal treatment approaches for patients. Considering the continuous progress being made in understanding PDAC pathogenesis and designing new therapies, it was considered timely to develop an up-to-date thematic issue of Advances in Cancer Research (ACR) focused on PDAC. In this thematic issue, we have included ten review articles by experts that cover cancer disparities, PDAC pathobiology, the roles of the tumor microenvironment, tumor heterogeneity, PC stem cells, genetic and signaling events critical for PDAC pathogenesis, Immunotherapy and chemoresistance in PDAC, and different PDAC mouse models. This special issue highlights recent research progress in PDAC, which bridges the gap between basic and clinical research.

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