Books in Life sciences

71-80 of 20378 results in All results

Cancer Drug Design and Discovery

3rd Edition
October 1, 2029
Stephen Neidle + 1 more
English

Cancer Drug Design and Discovery, 3rd edition continues the tradition of bringing a complete and authoritative reference that features the identification of cellular and molecular targets and their involvement in human cancer initiation and progression. This book aims at helping lead drug discovery researchers to the development of more effective anticancer therapies. Organized in three major parts, the first five chapters deal with an introduction to cancer drug discovery, pharmacogenomics and precision medicine, natural products, structural biology and pre-clinical, models. The second part focusses on therapies, covering nucleic acid-based therapies, Proteolysis-targeting chimera (protac), inhibition of DNA repair, cell signaling agents, immunotherapies, antibody-drug conjugates, and epigenetics for cancer treatment. The final part deals with the practice of cancer drugs in the clinic setting, including IP, failure modes, regulation, and registration of anti-cancer drugs. Multi-authored by leading researchers and clinicians in the field, this book is a valuable for pharma researchers both in academia and corporate settings. The foundational content provided by the authors can also be of interest to oncologists and research physicians specialized in the covered types of cancer.

Case Studies in Novel Food Processing Technologies

2nd Edition
September 1, 2029
C J Doona + 2 more
English

Novel food processing technologies have significant potential to improve product quality and process efficiency. Commercialization of new products and processes brings exciting opportunities and interesting challenges. Case Studies In Novel Food Processing Technologies provides insightful, first-hand experiences of many pioneering experts involved in the development and commercialization of foods produced by novel processing technologies.The second edition brings all Case Studies fully revised and all recent updates in the field, besides a bigger focus on Thermal Technologies. With its team of distinguished editors and international contributors, the book is an essential reference for professionals in industry, academia, and government.

Neuromodulation for Pain Control

1st Edition
September 1, 2029
Gerald Leisman + 1 more
English

The Handbook of Rehabilitation Sciences series is a multi-volume, multi-disciplinary handbook of rehabilitation sciences which provides a single vehicle for the many fields that converge on rehabilitation. These fields each have an independent literature and language that does not converge on the practice of related disciplines. This results in a fractured rather than holistic understanding of what is necessary for a science of returning the impaired to optimized function. This project provides a unified platform for the cross– disciplinary presentation of ideas in rehabilitation sciences thereby creating a resource for practitioners and researchers in all disciples associated with rehabilitation applications. Neuromodulation for Pain Control specifically covers stimulation to treat patients suffering from chronic pain. The volume is divided into three main sections: spinal cord stimulation, peripheral nerve stimulation, and intrathecal therapies and control of spasticity for pain control. Each section introduces the concept, discuses anatomy and physiology associated to the pain and various treatment options to manage the pain. It also provides pharmacological options, exploring non-opioid agents and new molecules for intrathecal use and delivery.

Neurorehabilitation

1st Edition
September 1, 2029
Gerald Leisman + 1 more
English

The Handbook of Rehabilitation Sciences series is a multi-volume, multi-disciplinary handbook of rehabilitation sciences which provides a single vehicle for the many fields that converge on rehabilitation. These fields each have an independent literature and language that does not converge on the practice of related disciplines. This results in a fractured rather than holistic understanding of what is necessary for a science of returning the impaired to optimized function. This project provides a unified platform for the cross– disciplinary presentation of ideas in rehabilitation sciences thereby creating a resource for practitioners and researchers in all disciples associated with rehabilitation applications. Neurorehabilitation aims to aid recovery from an injury, disease or disorders of the nervous system. Before delving into the practice of neurorehabilitation the reader is first introduced to neural plasticity, which allows the neurons to compensate for injury and disease and to adjust their activities in response to new situations or to changes in their environment. Understanding this concept is crucial to neurorehabilitation. The volume provides detail information on symptom-specific neurorehabilitation, vegetative and autonomic dysfunctions, and disease-specific neurorehabilitation systems. This book is ideal for practitioners in the field looking for a specific treatment option for their patients.

Rehabilitation of Neurodevelopmental Disorders

1st Edition
September 1, 2029
Gerald Leisman + 1 more
English

The Handbook of Rehabilitation Sciences series is a multi-volume, multi-disciplinary handbook of rehabilitation sciences which provides a single vehicle for the many fields that converge on rehabilitation. These fields each have an independent literature and language that does not converge on the practice of related disciplines. This results in a fractured rather than holistic understanding of what is necessary for a science of returning the impaired to optimized function. This project provides a unified platform for the cross– disciplinary presentation of ideas in rehabilitation sciences thereby creating a resource for practitioners and researchers in all disciples associated with rehabilitation applications. Rehabilitation of Neurodevelopmental Disorders provides an in-depth reference to neurodevelopmental disabilities, including concepts, definition and epidemiology of disabilities affecting children. The volume editors explore how each disability is diagnosed using screening methods and imaging techniques. The volumes continues with neonatal and early interventions and rehabilitations for autism, ADD/ADHD, childhood OCD and more.

The Osteology of Reptiles and Amphibians

1st Edition
September 1, 2029
Beth Reinke
English

The Osteology of Reptiles and Amphibians: A Modern Comparative Atlas of North American Species is a comprehensive guide on all skeletal systems and bone compositions of herpetofauna, including turtles, crocodiles, lizards, and snakes. This book looks at the largest concentration of reptilian and amphibian species found across the United States, Canada, Mexico, and beyond. Fundamental overviews and descriptions for osteological identification, herpetological evolution, and the study of functional and comparative morphology are covered. Line drawings separated by bone type from all major herpetofauna groups round out the content. Users will find detailed, scaled content that allows researchers to collect data within major groups.This book represents the first of its kind, offering herpetologists, vertebrate biologists, paleontologists, and zooarchaelogists a core visual resource for studying and understanding herpetofauna osteology. It will also be useful for students in animal biology, herpetology, and osteology courses.

Pathobiology of Rare Lung Diseases

1st Edition
September 1, 2029
Cormac McCarthy + 1 more
English

Pathobiology of Rare Lung Diseases provides an overview of the pathogenic mechanisms underlying this broad variety of conditions. This up-to-date reference focuses on the molecular mechanisms involved and provides insights into the changing therapeutic landscape for rare lung diseases. The study of rare lung diseases can inform our understanding of pathogenic mechanisms of more common disorders. Many of these conditions can be studied in detail, and an increasing wealth of knowledge exists regarding the pathogenesis of these conditions. Some are monogenic, while others have clearly defined pathways that allow for deep understanding and exploration of the molecular basis of disease. As a considerable leap has been made in the last decade in rare lung disease research, this book comprehensively covers these scientific breakthroughs to inform readers on future potential, strategies and the direction of research for these conditions.

Cellular Processes in the Aging Brain

1st Edition
September 1, 2029
Claudio Torres
English

Cellular Processes in the Aging Brain provides an exploration of the cellular and molecular processes underlying aging in the context of the brain. Aging is the greatest risk factor for the development of most of neurodegenerative disorders; however, the aspects of the aging process that predispose us to the development of brain pathology are largely unknown. The senescence process is an irreversible growth arrest triggered by various events including telomere dysfunction, DNA damage, oncogene activation, oxidative stress and proteasome inhibition. The presence of senescent cells in the human brain could be critical because they display an altered pattern of secretion known as the senescence-associated secretory phenotype (SASP), a complex mixture of factors that profoundly affect neighboring cells and tissues by creating a pro-inflammatory microenvironment. This book is split into three parts, the first covers the physiological background, the second part covers basic mechanisms of cellular processes impacting the aging brain, and the third part introduces novel interventions, allowing for an understanding of the situation and paths to move forward. Cellular Processes in the Aging Brain is the first book to look specifically at the cellular process of aging in the brain, and it will be of great use to researchers in the field of cellular senescence and neuroscience, researchers with interest in basic science and novel translational approaches and advanced students as well as research-focused clinicians.

Foundational Neuroscience

1st Edition
August 1, 2029
Norbert R. Myslinski
English

Foundational Neuroscience: An Introduction to the Field is a unique introduction to this complex field. Providing a foundational introduction to complex brain concepts, this volume features almost 30 chapters covering brain function, dysfunction and research. With a focus on anatomy, physiology and pathology, chapters delve into important concepts in brain research, including neuroplasticity, intelligence, memory, emotions, consciousness, vision, hearing, taste, smell, touch, movement and biomedical research. Unique offerings include career guides, suggested readings, Q&As and neuroethics.

Gammadelta T Cells in Cancer Immunotherapy

1st Edition
August 1, 2029
Ilan Bank + 2 more
English

Gammadelta T cells in Cancer Immunotherapy shows how the potential of γδ T-cells can effectively be translated into clinical benefit in cancer immunotherapies. With a strong focus on finding alternatives to current T cell mediated cancer immunotherapies, the book can also be used as a baseline initial introduction to the field of gamma delta immunotherapy. In 13 chapters, it describes different approaches to a specific model of gammadelta immunotherapy, including ‘delta one T’ (DOT) and Allogeneic CAR. It also describes the rationale for the use of gamma delta cells in immunotherapy, strategies, therapies, and cancer treatment.Users will find out about the growing interest in the scientific and medical community, while also becoming familiarized with the basic biology of gammadelta T cells, the pre-clinical studies implying their utility in immunotherapy, and with the studies of clinical applications of different forms of gammadelta T cell immunotherapeutic.