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Books in Life sciences

  • Contemporary Problems in Plant Anatomy

    • 1st Edition
    • December 2, 2012
    • Richard White
    • English
    Contemporary Problems in Plant Anatomy contains the proceedings of a plant anatomy symposium that took place at Duke University and The University of North Carolina at Chapel Hill in 1983. The symposium addressed challenges in four basic research areas in contemporary plant anatomy: leaf development, floral development, differentiation of cells and tissues, and systematic and ecological anatomy. The book highlights new techniques and approaches for dealing with problems in each of these areas. Organized into 12 chapters, this volume begins with an overview of the stem-conducting tissues in monocotyledons; the development of vascular tissue patterns in the shoot apex of ferns; the role of subsidiary trace bundles in stem and leaf development of the dicotyledoneae; and the structure of phloem. It then discusses the cellular parameters of leaf morphogenesis in maize and tobacco; alternative modes of organogenesis in higher plants; morphological aspects of leaf development in ferns and angiosperms; the origin of symmetry in flowers; and intraspecific floral variation. The reader is also introduced to structural correlations among wood, leaves, and plant habit; relationships between structure and function in trees; and the development of inflorescence, androecium, and gynoecium with reference to palms. This book is a valuable source of information for plant anatomists.

  • Immune Regulators In Transfer Factor

    • 1st Edition
    • December 2, 2012
    • Amanullah Khan
    • English
    Immune Regulators in Transfer Factor is a collection of papers presented at the Third International Symposium on Transfer Factor held on October 12-14, 1978 at the Wadley Institutes of Molecular Medicine in Dallas, Texas. Contributors focus on immune regulators occurring in transfer factor, a dialyzable component of leukocyte lysates. The isolation and characterization of the immunologically active molecules, as well as tests for in vitro and in vivo, are described. This volume is organized into five sections encompassing 73 chapters and begins with an overview of animal models used in research on dialyzable leukocyte extracts, their modulation of suppressor activity, effects in mice, and activity and specificity of human and bovine transfer factor. The next section considers in vitro testing, touching on topics such as the quantification and biological assays of transfer factor; the specificity of transfer factor action on macrophage migration; and the effect of transfer factor therapy on antibody-dependent cytotoxic activity in humans. The reader is then introduced to the preparation, purification, and characterization of transfer factor, as well as clinical investigations ranging from phase I studies to randomized controlled trials. This book will be of interest to scientists and researchers in fields such as molecular medicine, biomedicine, microbiology, immunology, oncology, pathology, and immunotherapy.

  • Comparative Endocrinology V1

    • 1st Edition
    • December 2, 2012
    • U.S. Von Euler
    • English
    Comparative Endocrinology: A Treatise in Two Volumes, Volume I: Glandular Hormones focuses on animal morphology, physiology, and chemistry and systematic and comprehensive account of endocrine principles from the comparative consideration. The selection first offers information on hypothalamic control of anterior pituitary and neurohypophyseal hormones. Discussions focus on adrenocorticotropin, thyrotropin, gonadotropins, physiological significance of the neurohypophyseal hormones in mammals, and physiological significance of the neurohypophyseal hormones in nonmammalian vertebrates. The text then takes a look at pituitary hormones affecting chromatophores and female gonadal hormones. The publication examines male gonadal hormones and adrenocortical hormones. Topics include action of testicular estrogen and ovarian testosterone, source of sex hormones in the male, factors regulating testicular functions, biochemistry of androgens, and functions of the adrenocortical hormones. The book then tackles chromaffin cell hormones, thyroid hormones, and parathyroid glands. The selection is a dependable source of data for readers interested in glandular hormones.

  • Antimalarial Agents

    Chemistry and Pharmacology
    • 1st Edition
    • December 2, 2012
    • Poul Thompson
    • English
    Medicinal Chemistry, Volume 12: Antimalarial Agents: Chemistry and Pharmacology presents the essentials of both biology and chemistry pertinent to the chemotherapy of malaria. This book discusses the nature of the disease, the physiology and biochemistry of the plasmodia, and the mode of action of drugs. Organized into 19 chapters, this volume begins with an overview of the most intensive efforts to develop synthetic antimalarial drugs. This text then examines how drugs are evaluated as well as the specific chemotherapy in malaria. Other chapters consider the diversity of chemical structures exhibiting antimalarial activity with emphasis on structure–activity relationships and methods of synthesis. This book discusses as well the plasmodial effects by quinine in vivo. The final chapter deals with the miscellaneous structures known to have activity against some types of plasmodial infection in animals. This book is a valuable resource for chemists and biologists involved in the development of antimalarial drugs.

  • Comparative Nutrition Of Man and Domestic Animals

    • 1st Edition
    • December 2, 2012
    • H Mitchell
    • English
    Comparative Nutrition of Man and Domestic Animals, Volume I discusses practical phases in the evaluation of the nutrient requirements of man and his domesticated animals and the factors that modify these quanta. This book also covers various nutrients' biochemical nature, functions, and participation in the energy transactions of the body. Organized into 11 chapters, the book initially discusses the principles of the basal metabolism and the activity increment and their role in evaluating maintenance requirement of human and animal for energy. The subsequent chapter focuses on the maintenance requirement of protein under stress and non-stress conditions. Other chapters discuss nutrient requirements for maintenance, such as water and minerals. The book also examines the nutrient requirements for muscle activities, growth, senescence, reproduction, and lactation. A discussion on the storage of nutritive material, such as water, protein, minerals, vitamins, and energy, is included. This volume is an invaluable source for organic chemists, biochemists, animal physiologists, zoologists, and nutritionists.

  • Cell Biology of the Major Histocompatibility Complex

    • 1st Edition
    • December 2, 2012
    • Benvenuto Pernis
    • English
    Cell Biology of the Major Histocompatibility Complex documents the proceedings of a symposium on ""Cell Biology of the Major Histocompatibility Complex"" held at Arden House on the Harriman Campus of Columbia University from June 8 -10, 1984. The meeting was the ninth of the P & S Biomedical Sciences Symposia. The book is organized into five parts. Part I on the structure of MHC molecules includes papers on human histocompatibility antigens; the cloning of human MHC; and organization of the genes of the H-2 complex. Part II on alternate forms of MHC molecules includes studies on the expression of a secreted form of the MHC class I antigen and alternative splicing in the H-2 multigene family. Part III deals with MHC biosynthesis, intracellular transport, and membrane expression. It includes studies on the manipulation of glycans on antigens of the MHC and dynamics of MHC molecules in lymphoid cells. Part IV on homologues of class I MHC molecules covers topics such as Tla expression in normal and malignant cells and the Qa series of antigens. Part V on the association of MHC with antigens includes studies such as histocompatibility molecules as immune response gene products and molecular nature of T-cell recognition of antigen.

  • The Plasma Proteins V4

    Structure, Function, and Genetic Control
    • 2nd Edition
    • December 2, 2012
    • Frank Putnam
    • English
    The Plasma Proteins: Structure, Function, and Genetic Control is a systematic account of the structure, function, and genetic control of plasma proteins. Advances in the characterization and posttranslational modification of plasma proteins are discussed, along with the structure of a variety of plasma proteins such as serum albumin, glycoproteins, and serum lipoproteins, and immunoglobulins. Comprised of six chapters, this volume begins with a review of progress in plasma proteins, focusing on their three-dimensional structure, characterization, and microheterogeneity as well as genetic polymorphism and chromosomal mapping. The second chapter gives a comprehensive summary of the structure of nearly 100 proteins, from serum albumin and glycoproteins to serum lipoproteins, thyroxine-binding proteins, and immunoglobulins. The reader is then introduced to human plasma proteins of unknown function, together with high-resolution two-dimensional electrophoretic mapping. The remaining chapters explore developments in the structural study of carbon hydrates; synthesis, structure, and function of the oligosaccharides of plasma glycoproteins; and the evolution of the vertebrate plasma proteins. This monograph will be of interest to molecular biologists and biochemists.

  • Biogenesis of Antibiotic Substances

    • 1st Edition
    • December 2, 2012
    • Zdenko Vanek
    • English
    Biogenesis of Antibiotic Substances covers the proceedings of a panel discussion on ""Basic Research and Practical Aspects of Antibiotic Production"" held during the Antibiotic Congress in Prague. This book is organized into 25 chapters that cover the regulating mechanisms of primary antibiotic metabolite biosynthesis. This text describes the relationship between secondary metabolite production and synthesis of cell matter or cell wall. The opening chapters describe the parasexual cycle and some of the ways in which the cycle may be used for strain improvement, as well as the applications of refined techniques of genetic recombination and the principles of biochemical genetics to the field of antibiotics. The next chapter deals with cultural and fermentative characteristics of A-type isolates obtained from progenitor and representative member strains of the Wisconsin Family of Strains of Penicillium chrysogenum. Considerable chapters are devoted to the metabolite biosynthesis, such as geodoxin and related compounds; secondary metabolism of penicillins, gibberellins, and griseofulvin in fungi; and tetracycline metabolites. The book goes on examining the stereochemical aspects of macrolide antibiotics. It also describes the biosynthetic pathways involving ring cleavage of carbocyclic compounds, as well as the biosynthesis of different peptide antibiotics and of actinomycins and its relationship to protein synthesis. The production of phenazines is also explained. Other chapters consider other metabolites, such as those that decarboxylate, the malonate, and the 3-nitropropionic acid. A discussion on the role of carbohydrates and phosphate in the biosynthesis of different types of antibiotics is included. Lastly, microbiological assay procedures for antibiotic research and influencing factors are presented.

  • The Proteins V2A

    Chemistry, Biological Activity, and Methods
    • 1st Edition
    • December 2, 2012
    • Hans Neurath
    • English
    The Proteins, Volume II: Chemistry, Biological Activity, and Methods, Part B is a six-chapter text that explores the chemical and biological aspects of proteins. This book deals first with the general properties and components of plasma proteins, followed by a discussion on the protein components of immune reactions. The subsequent chapters describe the structure of fibrous and muscle proteins, including silk fibroin, keratin, and collagen. A chapter presents the methods of preparation, physicochemical properties, chemical composition, stability, and enzymatic activity of proteolytic enzymes. The last chapter emphasizes the half lives and replacement rates of the various proteins in animal tissues. Biochemists, physiologists, and medical researchers will find this book invaluable.

  • Current Research in Protein Chemistry

    • 1st Edition
    • December 2, 2012
    • Villafranc
    • English
    Current Research in Protein Chemistry: Techniques, Structure, and Function focuses on the techniques and methods used for determining the structure and function of proteins. Topics covered range from protein folding and stability to catalysis by chimeric proteins, amino acid and peptide analysis, applications of mass spectrometry to peptide and protein analysis, and protein sequencing. This book is divided into six sections encompassing 55 chapters. The first chapter describes a novel method for protein hydrolysis by means of microwave irradiation that uses Teflon-Pyrex tubes. This is followed by a discussion of the application of high performance capillary electrophoresis to the analysis of amino acids. The sections that follow focus on mass spectrometric methods, protein sequencing, and capillary electrophoresis as well as protein stability, chimeric proteins and enzyme modifications, and protein structure prediction. The crystal structure of human interleukin-1alpha, the acid-denatured states of proteins, solubility of recombinant proteins expressed in Escherichia coli, and catalysis by chimeric proteins are considered. The reader is also introduced to peptide mapping and internal sequencing of proteins from acrylamide gels, new approaches to covalent sequence analysis, alkaline denaturation of hemoglobin, and measurements of disulfide bond stabilities in protein folding intermediates. Students and researchers interested in protein chemistry will find this book extremely helpful.

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