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Books in Life sciences

  • The Emergency of Order in Developing Systems

    • 1st Edition
    • Michael Locke
    • English
    The Emergence of Order in Developing Systems is a collection of papers presented at the 27th Symposium of the Society for Developmental Biology, held in Ithaca, New York in June 1968. Contributors focus on the emergence of orderly patterns during development, touching on topics ranging from the three-dimensional structure of the protein molecule to the polymerization of structural units, the self-assembly of microtubules in axonemes, and the patterning of plant cell walls. This volume is organized into four sections encompassing 11 chapters and begins with an overview of the emergence of order during cellular differentiation and growth, paying particular attention to the spontaneous formation of the three-dimensional structure of proteins. The next chapters explore self-association reactions in solutions of myosin molecules; ordering of subcellular units; factors that order the distribution of microtubules and thus ultimately pattern the shape of the cell; the biochemical organization of cytoplasmic membranes through self-assembly; and patterning in cell walls of higher plants. The book also explains the emergence of order in tissues and organs, and then concludes with a discussion on the emergence of order on the behavioral level. This book will be of interest to developmental biologists and embryologists.

  • Prostaglandin Research

    • 1st Edition
    • Pierre Crabbe
    • English
    Prostaglandin Research reviews the status of prostaglandin research, with particular emphasis on chemistry. This book highlights the role of scientific research in society in attempting to find drugs, with potential application to therapy, the chief impetus for prostaglandin research. This volume is organized into seven chapters and begins with an overview of the origin and properties of prostaglandins and then outlines the stage of research in the area of biosynthesis of natural entities, especially endoperoxides and thromboxanes. The reader is then introduced to a rich source of natural prostaglandins, the gorgonian Plexaura homomalla, and the pharmacology of prostaglandins. The physical methods used in prostaglandin research are considered, along with the chemistry of natural and modified prostaglandins. This book is aimed at experts in the field, as well as scientists with a general interest in chemistry and biology.

  • The Glycoconjugates

    Mammalian Glycoproteins and Glycolipids
    • 1st Edition
    • Martin Horowitz
    • English
    The Glycoconjugates: Mammalian Glycoproteins and Glycolipids, Volume I is a collaboration of different experts in the field of molecular biology on the subject of glycoconjugates. The text discusses the historical aspect, nomenclature, biosynthesis, and catabolism of glycoconjugates and their role in normal and pathological processes. Also covered are topics such as the purification of glycoproteins; the elucidation of the amino acid sequence of glycoproteins; the glycoproteins found in the different parts of the human body; glycoenzymes; and glycohormones. The book is recommended for molecular biologists, organic chemists, and biochemists who would like to know more about glycolipids and glycoproteins and their applications.

  • Advances in Physiology, Biochemistry, and Function V4

    • 1st Edition
    • A.D. Johnson
    • English
    The Testis: Advances in Physiology, Biochemistry, and Function, Volume IV, provides an overview of the state of knowledge in the physiology, biochemistry, and function of the testis. This volume updates those areas of greatest research activity and introduces in a more complete manner those topics which have developed as subject areas in themselves. It includes a chapter on testicular steroidogenesis, which updates and expands the chapter appearing in Volume II. In addition, chapters on the role of FSH in the testis, the specialized (largely endocrine) functions of the Sertoli cells, and the entire account of the tubular hormone inhibin have all been extensions of material in the original chapter on testicular endocrinology. Similarly, separate chapters on blood flow in the testis, fluid secretion, and the blood-testis barrier all report data on subjects largely unsuspected when Volumes I-III were published. Neither the first three volumes nor is the present one intended primarily for the nonprofessional biologist or the popular reader. The coverage should be most useful and informative to professional biologists. It is anticipated that this volume will also be of interest to advanced students of animal biology as an authoritative, comprehensive, and convenient review of significant recent information concerning the testis.

  • Membranes, Mitochondria, and Connective Tissues

    • 1st Edition
    • Isidore Gersh
    • English
    Submicroscopic Cytochemistry, Volume II: Membranes, Mitochondria, and Connective Tissues presents laboratory findings and theoretical aspects of the cytochemistry of cellular membranes, mitochondria, and connective tissues. Emphasis is on the molecular and macromolecular organization of cellular membranes, along with the origin and distribution of the major macromolecular aggregates of connective tissue. This volume consists of 11 chapters and begins by discussing the results of cytochemical studies on lipid and protein components of membranes in acinar and hepatic cells of the murine pancreas. The following chapters focus on densitometric studies of lipid membranes in pancreatic acinar cells of the mouse; the distribution of lipids and proteins in mitochondria of hepatic and exocrine pancreatic cells of adult mice, and of nucleic acids in mitochondria of embryonic cells; and possible precursor granules in fibroblasts, chondrocytes, and osteoblasts. The distribution of DNA and of soluble and insoluble RNAs in chondrocytes of the epiphyseal plate of the rat tibia is also examined, along with vascularity in tendons of young rats. This monograph will be of interest to cytochemists, biochemists, and molecular biologists.

  • Inhibition and Destruction of the Microbial Cell

    • 1st Edition
    • W Hugo
    • English
    Inhibition and Destruction of the Microbial Cell focuses on the effects of various classes of toxic chemical agents on microbial cell. This book is organized into 14 chapters that cover the topics from two points of view: the agent and the target (the microbial cell). The introductory chapters are devoted to the inhibitory effects of elevating temperature and to the lethal effect of environmental thermal energy supply restriction on growing bacteria. A chapter focuses on the effect of various classes of antibacterial compounds, such as 4-amino-quinaldinium and 8-hydroxyquinoline derivatives, chlorhexidine, amidines, halogens, dyes, and nitrofurans. The subsequent chapters examine the effects of other chemical agents on microorganisms, including toxic gases, solutes, ions, and radiations. The book goes on examining the inhibition and destruction of specific microorganisms, such as Pseudomonas aeruginosa, Enterobacteriaceae, Mycobacteria, Cocci, bacterial spores, molds, yeasts, and viruses. The last chapter discusses the effect of the cultural prehistory of microorganisms upon their response to inhibition and destruction. This book is an invaluable resource for graduate research workers and scientists in pure and applied microbiology. This will also be a good reference for undergraduates reading specialized courses at honors level in microbiology or applied courses in food science and agriculture. Furthermore, it will be of interest to the medical profession, especially those involved in public health and pathology, as well as to scientists in the pharmaceutical industry.

  • Organ Culture

    • 1st Edition
    • J Thomas
    • English
    Organ Culture provides information pertinent to the fundamental aspects of the study of autodifferentiation. This book discusses the physiological differentiation, the action of substances that inhibit or stimulate growth, and the interactions of associated organs. Organized into 10 chapters, this book begins with an overview of the differentiation of embryonic organs in natural media. This text then presents the study of differentiation in synthetic solid or liquid media and explains the biochemical and physiological requirements of the tissues. Other chapters consider the problems of sexual differentiation and intersexuality in vitro by providing a comparative study of avian and mammalian embryos. This book analyzes as well the interactions between hormones, inhibitor substances, and receptor organs in vitro. The final chapter deals with the study of organ chimeras in vitro and the related study of the organ culture of malignant tumors. This book is a valuable resource for embryologists and research workers.

  • Biochemistry of Human Cancer

    • 1st Edition
    • Oscar Bodansky
    • English
    Biochemistry of Human Cancer focuses on advances in the application of biochemistry to the study of human cancers, such as neoplastic immunoglobulinopathi... cancer of the bladder, tumors of the neural crest, leukemias and lymphomas, and neoplasms of the bone. It also examines certain features of human cancer ranging from general metabolic characteristics to enzymic aspects and immunochemical considerations. Organized into 18 chapters, this book begins with an overview of the general metabolic features of cancer, with emphasis on the metabolism of lipids, proteins, and carbohydrates. It then discusses the important biochemical aspects of pulmonary and prostatic neoplasms, including the serum acid and alkaline phosphatase activities of prostatic carcinoma. The remaining chapters look at the role of enzymes and immunoglobulins in cancer, the tryptophan metabolism in cancer of the bladder and the carcinoid syndrome, the link between amino acid metabolism and tumors of the neural crest, and the neoplasms of the digestive tract and the accessory organs (pancreas and liver). The book explains the metabolism of purines and pyrimidines in cancer, hypercalcemia in neoplastic disease without evidence of bone metastases, and neoplasms of other organs, such as the pituitary gland, thyroid, testis, and adrenal cortex. Brief case reports from the literature are included to illustrate correlations between biochemical and clinical findings. Scientists, biochemists, and clinical investigators concerned with the biochemistry of human cancer will find this book highly informative.

  • Introduction to a Submolecular Biology

    • 1st Edition
    • Albert Szent-Gyorgyi
    • English
    Introduction to a Submolecular Biology focuses on the study of the electronic interactions of biological molecules. This book discusses the energy cycle of life, units and measures, electronic mobility, and problems of charge transfer. The three examples of charge transfer—quinone-hyd... riboflavine (FMN) and serotonin, and cortisone I2 are elaborated. This text deliberates the problems and approaches on the mechanism of drug action, adenosine triphosphate (ATP), chemistry of the thymus gland, and living state. Brief remarks on water, ions, and metachromasia are also included. Other topics covered include the redox potentials, ionization potentials and electron affinities, orbital energies, electromagnetic coupling resonance transfer of energy, and semiconduction. This publication is a good source for biochemists, biologists, and specialists aiming to acquire basic knowledge of submolecular biology.

  • Transplantation Antigens

    Markers of Biological Individuality
    • 1st Edition
    • Barry Kahan
    • English
    Transplantation Antigens: Markers of Biological Individuality investigates transplantation antigens and their function as markers of biological individuality. Topics covered include transplantation antigens of the human fetus, trophoblast, and spermatozoa; tissue distribution and cellular location of transplantation antigens; and serologic identification of human transplantation antigens. The biological significance of cross-reactions between histocompatibility antigens and antigens of bacterial and/or heterologous mammalian origin is also examined. This book is comprised of 25 chapters and begins with an introduction to the phylogeny of transplantation reactivity, followed by a discussion on the appearance of transplantation antigens in the embryo and fetus and the ways in which these antigens interact with or are masked from the immunocytes of the pregnant female. The next chapter analyzes the data on the detection of transplantation antigens on human fetal cells, cells of trophoblastic origin, and spermatozoa. The intracellular distribution of transplantation antigens is also considered, along with the extraction of membranous transplantation antigens by pressure homogenization; the molecular nature of HL-A antigens; and solubilization of histocompatibility antigens with detergents. This monograph will appeal to biologists, physiologists, immunologists, and clinicians.

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