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Books in Life sciences

  • Chemical Structure–Biological Activity Relationships: Quantitative Approaches

    Proceedings of the 3rd Congress of the Hungarian Pharmacological Society, Budapest, 1979
    • 1st Edition
    • October 22, 2013
    • F. Darvas
    • English
    Chemical Structure-Biological Activity Relationships: Quantitative Approaches, Volume III, documents the proceedings of the 3rd Congress of the Hungarian Pharmacological Society held in Budapest, 1979. This volume focuses on the methodological aspects of QSAR. It also aims to inform the reader about the QSAR research conducted in East-European countries. This volume contains 38 presentations organized into six sections. Several lecturers deal with ""real prediction"" cases, i.e. activity estimation prior to the synthesis of the compounds. A particularly abundant section is devoted to the question of how the receptor models can be built up by means of QSAR calculations. Other sections present mathematical models and algorithms which could be applied to improve further the effectiveness of QSAR calculations. As another unique feature, a separate section treats the quantitative aspects of peptide structure-activity relationships—a field seemingly backward despite its evident importance. Hydrophobicity and its influence on biological potency along with the relationship of steric properties and biological activity are also discussed.

  • Enzymes in Blood Plasma

    • 1st Edition
    • October 22, 2013
    • Benno Hess
    • English
    Enzymes in Blood Plasma gives a comprehensive account of the current state of research and practical application of biochemistry and biology, as well as the pathology and clinical aspects of plasma enzymes. Enzymes in blood plasma, for reasons of principle and methods, are not limited to plasma-specific enzymes, which are only briefly mentioned. Emphasis will rather be placed on plasma-nonspecific enzymes, i.e., enzymes of identical properties in plasma and serum. Their action is, for technical reasons, generally determined in serum. The enzymes in plasma will be stressed in this presentation, but the situation in other extracellular spaces and even extracorporeal areas such as urine, excreta, and feces will be included. There exists no basic difference of enzyme function in these biological areas. Many of the findings reported in this volume were obtained with the old units and methods, rather than the International Unit. For this reason, the section dealing with methods includes a table for conversion, which can be used for comparison of data, insofar as these data were obtained under optimalconditions of measurement.

  • The Scientific Basis of Drug Therapy in Psychiatry

    Proceedings of a Symposium Held at St. Bartholomew's Hospital, London
    • 1st Edition
    • October 22, 2013
    • John Marks + 1 more
    • English
    The Scientific Basis of Drug Therapy in Psychiatry is a collection of papers that covers the therapeutic effects and the mode of action of the various psychotropic drugs. The materials in the title are organized thematically based on the topic they tackle. The text first covers the articles on the basic concepts, such as anatomy and physiology of the emotions and their relation to psychoactive drugs, as well as the methods of assessment of psychological effects of drugs. The next three chapters cover the concerns with the psychotropic drugs that include clinical use, mode of actions, and pharmacology. The remaining paper talks about some of the considerations that need to be taken when administering psychotropic drugs. The book will be of great use to researchers and practitioners in behavioral science related disciplines, such as psychology, psychiatry, and neurology. Pharmacologists and medicinal chemists will also benefit from the text.

  • Forensic Toxicology

    Proceedings of a Symposium Held at the Chemical Defence Establishment, Porton Down, 29-30 June 1972
    • 1st Edition
    • October 22, 2013
    • Bryan Ballantyne
    • English
    Forensic Toxicology presents the legal and medical aspects of the detrimental effects of chemicals on humans. This book discusses the immediate and long-term consequences of accident or deliberate poisoning, the detection of such poisoning, and the interpretation of the possible importance of demonstrating exogenous substances in biological fluids and tissues. Organized into 14 chapters, this compilation of papers begins with an overview of the fundamental procedure and interpretation in forensic toxicology. This text then examines the ways in which enzymes may be used in the analysis of drugs. Other chapters consider the equipment and reagents required in the rapid tests for drugs in urine. This book presents as well barbiturate poisoning from the viewpoint of the forensic pathologist performing the post mortem over the cause of death. The final chapter deals with further advances in forensic toxicology. This book is a valuable resource for general practitioners, forensic toxicologists, forensic pathologists, and police officers.

  • Recent Developments in Poultry Nutrition

    • 1st Edition
    • October 22, 2013
    • D.J.A. Cole + 1 more
    • English
    Recent Developments in Poultry Nutrition is a collection of studies that cover important developments in poultry nutrition. The book presents 23 papers that deal with the various areas of concerns in poultry nutrition. The coverage of the text includes materials that deal with poultry diet, such as metabolizable energy evaluation of poultry diets; the impact of declaration of the metabolizable energy value of poultry feeds; and the influence of fiber on digestibility of poultry feeds. The book also deals with egg production issues, including the influence of nutritional factors on hatchability; eggshell formation and quality; and dietary phosphorus for laying hens. The text will be of great use to researchers and professionals in the poultry industry. Consumers will also find this book interesting since it discusses topics that can directly affect them.

  • Adaptation to Environment

    Essays on the Physiology of Marine Animals
    • 1st Edition
    • October 22, 2013
    • R. C. Newell
    • English
    Adaptation to Environment: Essays on the Physiology of Marine Animals contains a series of essays that is intended as a review of the special adaptations of marine organisms to the particular environmental conditions they are likely to encounter in the natural habitat. This book emphasizes developments in physiology of marine animals and on approaches to the study of the adaptations of marine organisms. This compilation also interprets the term “Physiology” in its widest sense to include all aspects of the functioning of the organism from the behavior of animals to the mode of function of enzymes. For this reason, structural adaptations have been reviewed in detail only where their functional role is understood and where they constitute a specific adaptation to defined environmental conditions. This publication benefits students and individuals conducting research on the physiology of marine animals.

  • Lesions and Transplantation

    • 1st Edition
    • October 22, 2013
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 7: Lesions and Transplantation describes the chemical and nonchemical production of lesions and preparation and development of transplants, implants, and grafts. This book consists of four sections—chemical and nonchemical lesioning; model systems utilizing lesioning; transplants, implants, and grafts; and assessment of lesions and transplants. In these sections, this volume discusses the excitotoxins as tools for producing brain lesions; use of acromelic acid for production of rat spinal lesions; and opioid and nonopioid antinociception as revealed by lesion studies. The endothelin-1-induced lesions in the brain as a new model of focal ischemia; fetal implants in the lesioned spinal cord of the rat; and hippocampal transplants in oculo are also elaborated. This book likewise covers the assessment of neurochemical function of brain transplants and in vitro electrophysiological analysis of in oculo. This publication is intended for neuroscientists, but is also beneficial to researchers conducting work on lesions and transplants.

  • Venoms of the Hymenoptera

    Biochemical, Pharmacological and Behavioural Aspects
    • 1st Edition
    • October 22, 2013
    • Tom Piek
    • English
    Venoms of the Hymenoptera: Biochemical, Pharmacological, and Behavioral Aspects contains papers that deals with the study of the venoms and toxins produced by insects belonging to the order of the Hymenoptera. The book provides a considerable amount of information in the study of the venoms of the Hymenoptera. There are chapters that focus on the history of the research made on the order of the Hymenoptera; the stinging apparatus; venom collection; physiological effects of venoms produced by particular insects belonging to the order; and the pharmacological uses of the venoms and toxins. Entomologists, physiologists, pharmacologists, biochemists, and researchers developing drugs and pesticides will find this text extremely useful.

  • Recent Advances in the Pharmacology of Toxins

    Proceedings of the First International Pharmacological Meeting Stockholm, 22-25 August, 1961
    • 1st Edition
    • October 22, 2013
    • H. W. Raudonat
    • English
    Recent Advances in the Pharmacology of Toxins brings together the proceedings of the Second International Pharmacological Meeting of the International Union of Physiological Sciences, held in Prague, Czechoslovakia, on August 20-23, 1963. The meeting provided a forum for discussing advances in the understanding of the pharmacology of toxins and addressed topics ranging from antagonists of bradykinin to the mode of the spread of tetanus toxin in experimental animals. This volume is comprised of 28 chapters and begins with an analysis of the effects of toxins from microorganisms on mammalian cellular metabolism and structure, followed by a review of SRS-A, a slow-reacting substance of anaphylaxis, as a potential factor in the symptoms produced by venoms and toxins. Subsequent chapters explore the release of pharmacologically active lipids by enzymes contained in toxins; the structure and function of some enzymes in snake venoms, with reference to disulfide linkages; biochemistry and pharmacology of small-molecular compounds of cobra venom; and the role of ganglioside in the mode of action of tetanus toxin. This book will be of particular value to pharmacologists and physiologists.

  • The Lung Circulation

    Physiology and Pharmacology
    • 1st Edition
    • October 22, 2013
    • Domingo M. Aviado
    • English
    The Lung Circulation deals with important aspects of the lung circulation, with emphasis on the physiology of the pulmonary and bronchial circulation and autonomic pharmacology. Topics covered range from the role of anoxia in pulmonary circulation to reflexes arising from the pulmonary circulation and neighboring structures. The release of chemical substances from the pulmonary and bronchial circulation is also discussed. This volume is comprised of 10 chapters and begins with a review of the influence of anoxia on pulmonary circulation as well as four pertinent effects of anoxemia, namely, respiratory stimulation; cardiac stimulation; systemic vasoconstriction and vasodilatation; and pulmonary vasoconstriction and vasodilatation). The following chapters focus on the regulation of bronchial circulation; autonomic nervous control of pulmonary circulation involving acetylcholine, anticholinesterases, and atropine; and the pharmacology of sympathomimetic drugs, sympathetic blocking drugs, ganglion stimulants, and blocking drugs. The final chapter is devoted to the pharmacology of the autonomic nervous system and considers drugs that stimulate chemoreflexes arising from the lung circulation, including veratrum alkaloids. This book will appeal to physiologists and pharmacologists.

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