Books in Life sciences

The Brain and Host Defense

1st Edition
Volume 9
December 24, 2009
Barry G. W. Arnason + 1 more
English
Hardback
9 7 8 0 4 4 4 5 3 5 4 4 3
eBook
9 7 8 0 4 4 4 5 3 5 4 5 0

It is now well recognized that the brain, and especially the hypothalamus, plays an important role in the regulation of immune reactions and inflammation. This book aims to review our current state of knowledge of this important field. Key historical findings are presented, and the reciprocal interactions between the brain and the immune system are examined. Particular emphasis is placed on inflammation, a critical host defense reaction that serves as an effector response for both the adaptive and innate immune systems.Mechanisms implicated in brain defense, as well as in more general host defense, are discussed. The regulatory influences of the brain on inflammatory responses are included with particular reference to the role of the hypothalamus, which is also the main director the hormonal regulation of immune/inflammatory. Gender-related differences in immune responsiveness, circadian modulator of immune responses, and evidence that behavioral conditioning (e.g. reward) of immune responses is possible are used as examples to reinforce the notion that the neuroendocrine system exerts a fundamental and complex regulatory influence on the immune system.

Neurology and Systemic Disease, An Issue of Neurologic Clinics

1st Edition
Volume 28-1
December 24, 2009
Alireza Minagar
English

This issue of Neurologic Clinics features 17 articles that address the neurologic implications of systemic illnesses. Articles include neurologic presentations of infective endocardititis; neurologic presentations of acid-base imbalance, electrolyte abnormalities, and endocrine emergencies; neurologic presentation of renal disease; neurologic manifestations of systemic lupus erythematosus in children and adults; neurologic complications of respiratory disease; neurologic presentations of nutritional deficiencies; neurologic presentations of gastrointestinal disease; neurotoxicity of radiation therapy; neurologic presentation of lyme disease and syphilis; neurologic aspects of drug abuse; neurologic manifestations of transplant complications; neurologic presentations of sarcoidosis; neurologic presentations of fungal infections; neurologic presentations of cardiac disease; neurologic presentation of AIDS; neurologic presentation of systemic vasculitis; and neurologic presentations of hepatic disease.

Biomaterials and Regenerative Medicine in Ophthalmology

1st Edition
December 18, 2009
Traian Chirila + 1 more
English
eBook
9 7 8 1 8 4 5 6 9 7 4 3 3

With an increasingly aged population, eye diseases are becoming more widespread. Biomaterials have contributed in recent years to numerous medical devices for the restoration of eyesight, improving many patients’ quality of life. Consequently, biomaterials and regenerative medicine are becoming increasingly important to the advances of ophthalmology and optometry. Biomaterials and regenerative medicine in ophthalmology reviews the present status and future direction of biomaterials and regenerative medicine in this important field.Part one discusses applications in the anterior segment of the eye with chapters on such topics as advances in intraocular lenses (IOLs), synthetic corneal implants, contact lenses, and tissue engineering of the lens. Part two then reviews applications in the posterior segment of the eye with such chapters on designing hydrogels as vitreous substitutes, retinal repair and regeneration and the development of tissue engineered membranes. Chapters in Part three discuss other pertinent topics such as hydrogel sealants for wound repair in ophthalmic surgery, orbital enucleation implants and polymeric materials for orbital reconstruction.With its distinguished editor and international team of contributors, Biomaterials and regenerative medicine in ophthalmology is a standard reference for scientists and clinicians, as well as all those concerned with this ophthalmology.

Innovations in Food Labelling

1st Edition
December 18, 2009
J Albert
English
eBook
9 7 8 1 8 4 5 6 9 7 5 9 4

Increasingly, consumers desire information about the health, safety, environmental and socioeconomic characteristics of food products. These traits often cannot be detected by sight, smell or taste. Therefore, consumers must use food labels to select products that meet their needs and preferences. The growing consumer and industry interest in food labels presents challenges for governments, which must ensure that the product information is accurate, truthful and not misleading to consumers. Governments must decide whether provision of information should be mandatory or voluntary. With the increase in global trade in food, there is a need to harmonize food labels so that product information is understood and relevant to foreign markets.Innovations in food labelling provides information about the principles and requirements of food labelling and reviews the latest trends in this important area. Following an introduction on the evolution of food labelling, further chapters cover the Codex Alimentarius and food labelling, international trade agreements, nutrition labelling, allergies and food labels and environmental and social labels, among other topics.An essential reference for food regulatory agencies, food law experts and professionals in the food industry responsible for labelling as well as consumer and environmental associations with an interest in labelling.

Molecular Biology

1st Edition
January 27, 2012
David P. Clark
English
eBook
9 7 8 0 1 2 3 8 1 4 3 5 7

Molecular Biology: Academic Cell Update Edition Study Guide aims to help students get a better grasp of important concepts in Molecular Biology: Academic Cell Update. Each of the chapters in this study guide contains a summary that lets students see the bigger picture, that is, how all the techniques fit together in that chapter. A list of terms is presented in a concise format rather than spread throughout the textbook chapter to help the student remember these key terms in preparation for exams. Student can also assess their knowledge of these key terms using the Fill-in-the-Blank questions. The conceptual questions can be used for either class discussion or for independent student study. The answer key has a full explanation for the problem rather than a simple list of the answers. This study guide attempts to help the students to think about molecular biology concepts in a scientific manner, focusing each chapter on a recent research article demonstrating the concepts in the chapter. Early on in the study guide, only one or two figures of a research article are chosen so students can focus their learning on the concepts in the chapter and not on information that will be presented later in the book. In the middle of this study guide, the entire article is explained in a figure by figure basis. Then, as the student becomes more and more familiar with molecular biology techniques and the scientific method, the relevant research section contains fewer details.

Meyler's Side Effects of Analgesics and Anti-inflammatory Drugs

1st Edition
December 16, 2009
Jeffrey K. Aronson
English
Hardback
9 7 8 0 4 4 4 5 3 2 7 3 2
eBook
9 7 8 0 0 8 0 9 3 2 9 4 1

Elsevier now offers a series of derivative works based on the acclaimed Meyler’s Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing biomedical researcher and/or clinician. Opioids and analgesics are members of a diverse group of drugs used to relieve pain. They are frequently used in combination with prescription and nonprescription pain relievers, and misuse is prevalent. Pain medicine specialists and physicians or surgeons will find this volume useful in prescribing the appropriate drugs for pain therapy and for preventing misuse of the medication.

Drug-Device Combination Products

1st Edition
December 15, 2009
Andrew Lewis
English
eBook
9 7 8 1 8 4 5 6 9 7 4 8 8

Drug delivery systems represent a vast area of research and development within biomaterials and medicine and the demand for sophisticated drug delivery devices continues to drive novel product development. Advanced drug delivery devices can offer significant advantages over conventional drugs and devices alone, such as increased efficiency, improved performance and convenience. The purpose of this book is to illustrate how effective drug delivery can be achieved by means other than tablets. The book will provide a thorough analysis of the fundamentals, applications and new technologies of drug-device combination products for use throughout the human body.Part one provides readers with an introduction and background to the field. Chapters in Part two discuss areas of application such as catheter based products, drug eluting stents and beads and anti-biotic loaded cements. Part three covers the development of drug device combination products with chapters on such topics as pre-clinical testing, sterilisation, patent issues and regulation of drug device combination products.With its distinguished editor and team of international contributors, Drug-device combination products: delivery technologies and applications is an invaluable reference for product development specialists, materials scientists and engineers in the biomedical industry and academia as well as those concerned with drug delivery.

Nanoneuroscience and Nanoneuropharmacology

1st Edition
Volume 180
December 3, 2009
Hari S. Sharma
English
Hardback
9 7 8 0 4 4 4 5 3 4 3 1 6
eBook
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This volume presents articles from the leading experts in the field in nanobiotechnology, providing students and researchers with a comprehensive review of the newly emerging area of neuroscience. All aspects of nanomaterials induced alteration in brain function are considered. Basic chapters on methods and ways to enhance nano-drug delivery into the brain are presented as well as chapters on functional and structural changes in the CNS, including gene expression and related issues. Particular attention is given to possible therapeutic advancement regarding nano-drug formulation and their role in neuroprotection.

Handbook of the Behavioral Neurobiology of Serotonin

1st Edition
Volume 21
December 2, 2009
Christian P. Muller + 1 more
English
Hardback
9 7 8 0 1 2 3 7 4 6 3 4 4
eBook
9 7 8 0 0 8 0 8 7 8 1 7 1

Serotonin (5-hydroxytryptamine... often cited as 5-HT) is one of the major excitatory neurotransmitter, and the serotonergic system is one of the best studied and understood transmitter systems. It is crucially involved in the organization of virtually all behaviours and in the regulation of emotion and mood. Alterations in the serotonergic system, induced by e.g. learning or pathological processes, underlie behavioural plasticity and changes in mood, which can finally results in abnormal behaviour and psychiatric conditions. Not surprisingly, the serotonergic system and its functional components appear to be targets for a multitude of pharmacological treatments - examples of very successful drugs targeting the serotoninergic system include Prozac and Zoloft. The last decades of research have not only fundamentally expanded our view on serotonin but also revealed in much more detail an astonishing complexity of this system, which comprises a multitude of receptors and signalling pathways. A detailed view on its role in basal, but also complex, behaviours emerged, and, was presented in a number of single review articles. Although much is known now, the serotonergic system is still a fast growing field of research contributing to our present understanding of the brains function during normal and disturbed behaviour. This handbook aims towards a detailed and comprehensive overview over the many facets of behavioural serotonin research. As such, it will provide the most up to date and thorough reading concerning the serotonergic systems control of behaviour and mood in animals and humans. The goal is to create a systematic overview and first hand reference that can be used by students and scholars alike in the fields of genetics, anatomy, pharmacology, physiology, behavioural neuroscience, pathology, and psychiatry. The chapters in this book will be written by leading scientists in this field. Most of them have already written excellent reviews in their field of expertise. The book is divided in 4 sections. After an historical introduction, illustrating the growth of ideas about serotonin function in behaviour of the last forty years, section A will focus on the functional anatomy of the serotonergic system. Section B provides a review of the neurophysiology of the serotonergic system and its single components. In section C the involvement of serotonin in behavioural organization will be discussed in great detail, while section D deals with the role of serotonin in behavioural pathologies and psychiatric disorders.

Primary Cilia

1st Edition
Volume 94
November 30, 2009
Roger D. Sloboda
English
Hardback
9 7 8 0 1 2 3 7 5 0 2 4 2
eBook
9 7 8 0 0 8 0 9 6 2 8 2 5

In recent years, the role of cilia in the study of health, development and disease has been increasingly clear, and new discoveries have made this an exciting and important field of research. This comprehensive volume, a complement to the new three-volume treatment of cilia and flagella by King and Pazour, presents easy-to-follow protocols and detailed background information for researchers working with cilia and flagella.

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