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Books in Life sciences

  • The Antigens

    Volume V
    • 1st Edition
    • Michael Sela
    • English
    The Antigens, Volume V is a comprehensive treatise covering all aspects of antigens, including their chemistry and biology as well as their immunologic role and expression. Four complex problems of direct relevance to human health are explored, namely, tumor antigens, antigens of helminths, cytotoxic lymphocytes, and complement. Comprised of four chapters, this volume begins with a review of classic studies of tumor-specific transplantation antigens, followed by a discussion on the detection and purification of tumor antigens; the immune response to tumor antigens; and the role of tumor antigens in the escape of tumors from immunological control. The reader is then introduced to some aspects of the different functions of antigens of helminths, along with the immune response in helminthiasis. The book also examines the generation, properties, and mode of action of antibody-independent cytolytic T lymphocytes before concluding with an analysis of the complement system and its reaction pathways as well as its role as an autoantigen. This monograph will be of interest to practitioners and researchers in immunology, experimental and clinical medicine, biochemistry, and other disciplines.

  • Antigen-Antibody Reactions In Vivo

    Methods in Immunology and Immunochemistry, Vol. 5
    • 1st Edition
    • Curtis A. Williams + 1 more
    • English
    Methods in Immunology and Immunochemistry, Volume V: Antigen-Antibody Reactions In Vivo deals primarily with immune phenomena in tissues or in cell preparations. This book covers a variety of topics, including anaphylaxis, tolerance, immune suppression with chemical agents, radiation effects, antibody synthesis in vitro, immunological methods, and applied electron microscopy. Organized into 10 chapters, this volume begins with an overview of systemic anaphylaxis investigations in other more resistant species. This text then presents the analysis of mechanisms involved in the pathogenesis of the Arthus phenomenon, which shed light on the understanding of other lesions of hypersensitivity. Other chapters consider the effects of antigen–antibody interaction on connective tissue. This book discusses as well the degree and duration of acquired tolerance. The final chapter deals with the application of electron microscopy in the elucidation of the mechanisms of immune reactions. This book is a valuable resource for immunologists, students, and research workers.

  • Disorders of Mineral Metabolism

    Trace Minerals
    • 1st Edition
    • Felix Bronner + 1 more
    • English
    Disorders of Mineral Metabolism, Volume I: Trace Minerals covers the pathophysiology of clinically relevant minerals and elements. This volume focuses on minerals whose average daily intake is under 50 mg. This text is composed of 12 chapters that tackle the clinical relevance and essentiality of various trace minerals in the human body, with particular emphasis on the disorders due to their abnormal metabolism. The trace mineral and elements considered in this volume include iron, coppers, zinc, lead, nickel, manganese, chromium, molybdenum, cadmium, aluminum, tin, lithium, and fluoride. Each chapter discusses the properties, body requirements, analysis, nutritional interactions, and toxicity of the mineral. This book will prove useful to biochemists, pathophysiologists, and workers in the medical field.

  • Structure–Function Relationships of Proteolytic Enzymes

    Proceedings of the International Symposium, Copenhagen June 16-18, 1969, No. 37 in the Series of the International Union of Biochemistry Sponsored Symposia
    • 1st Edition
    • P. Desnuelle + 2 more
    • English
    Structure–Function Relationships of Proteolytic Enzymes provides information pertinent to the fundamental aspects of proteolytic enzymes. This book presents the historical role of proteolytic enzyme as a group in protein and enzyme chemistry. Organized into 23 chapters, this book begins with an overview of the results obtained from investigation on the chymotrypsinogens of porcine origin. This text then examines the differences of amino acid sequence between chymotrypsin, trypsin, and elastase that affect the substrate binding site, which reflect the specificity differences between these enzymes. Other chapters consider the kinetic parameters related to the trypsin-catalyzed hydrolysis of several model peptides. This book discusses as well the acetylation of trypsin, which result in functional consequences varying from complete inactivation to promotion of activity. The final chapter deals with the physical properties of stem bromelain in comparison with the data for three other sulfhydryl proteases of plant origin. This book is a valuable resource for enzymologists, microbiologists, and biochemists.

  • Viruses

    A Compilation from the GenBank® and EMBL data libraries
    • 1st Edition
    • Edwin J. Atencio + 2 more
    • English
    Nucleotide Sequences 1986/1987, Volume VI: Viruses presents data that reflect the information found in GenBank Release 44.0 of August 1986. This book provides information pertinent to the unique international collaboration between two leading nucleotide sequence data libraries, one based in Europe and one in the United States. Organized into one section, this volume begins with an overview of the sequences, some basic identifying information, and some of the biological annotations. This text then discusses the EMBL Nucleotide Sequence Data Library, an international center of fundamental research with its main focus in the fields of cell biology, molecular structures, instrumentation, and differentiation. This book discusses as well the GenBank database established in 1982 by the National Institute of General Medical Sciences (NIGMS) of the U.S National Institutes of Health (NIH). This book is a valuable resource for molecular biologists and other investigators collecting the large number of reported DNA and RNA sequences and making them available in computer-readable form.

  • Biochemistry of Metabolism

    The Biochemistry of Plants
    • 1st Edition
    • David D. Davies
    • English
    The Biochemistry of Plants: A Comprehensive Treatise, Volume 11: Biochemistry of Metabolism provides information pertinent to the chemical and biochemical aspects of metabolism. This book discusses the control mechanisms of metabolism. Organized into nine chapters, this volume begins with an overview of the history of biochemistry and discusses the developments in the kinetics of regulatory enzymes. This text then examines a theory that explains how subunit interactions modulate the rate of conversion of a substrate into a product. Other chapters consider some relation between cell-wall elongation and cell-wall charge density and explore the subcellular localization of the enzymes of glycolysis. This book discusses as well the regulation of glycolysis and the pentose phosphate pathway. The final chapter deals with the pathways of C1 metabolism that are of prime importance, as the synthesis of several cellular constituents depends directly or indirectly on folate metabolism. This book is a valuable resource for plant biochemists, neurobiochemists, molecular biologists, senior graduate students, and research workers.

  • The Antigens

    Volume VI
    • 1st Edition
    • Michael Sela
    • English
    The Antigens, Volume VI is a comprehensive treatise covering all aspects of antigens, including their chemistry and biology as well as their immunologic role and expression. Parasite antigens and their immunogenicity in infected hosts are explored, along with the nature of the antibody-combining site and the phenomenon of immunological tolerance. Comprised of three chapters, this volume begins with a discussion on the dynamic aspects of the function of antibodies, paying particular attention to the structure of immunoglobulins and the folding of their domains; the dynamics of segmental flexibility; the kinetics of antibody-hapten association and the kinetic expression of elementary interaction; and the conformational transitions within the antibody molecule induced by hapten binding. The next chapter focuses on the immunogenicity of parasite antigens in infected hosts, citing such parasites as trypanosomes, Schistosoma mansoni, and Fasciola hepatica. The last chapter deals with immunological tolerance, its induction and duration, and its effect on the specificity of the immune response. This monograph will be of interest to practitioners and researchers in immunology, experimental and clinical medicine, biochemistry, and other disciplines.

  • Photosynthesis

    The Biochemistry of Plants
    • 1st Edition
    • M. D. Hatch + 1 more
    • English
    The Biochemistry of Plants: A Comprehensive Treatise, Volume 8: Photosynthesis provides information pertinent to the biochemistry of photosynthesis. This book focuses on the photosynthesis of higher plants but some consideration is given to algal and bacterial photosynthesis. Organized into 11 chapters, this volume begins with an overview of the excitation of a light-harvesting pigment by an absorbed light quantum. This text then discusses the evidence to support the hypothesis that chlorophyll–protein complexes are represented at the supramolecular level by some of the intramembranous particles seen on chloroplast freeze-fracture faces. Other chapters consider the absorption of light energy by accessory pigments and transferred to chlorophyll in the blue-green, red, and brown algae. This book discusses as well that certain cyanobacteria respond to the color of the incident light by altering their biliprotein composition. The final chapter deals with dark reaction of photosynthesis. This book is a valuable resource for plant biochemists, neurobiochemists, molecular biologists, senior graduate students, and research workers.

  • Meiosis and Mitosis

    Biochemistry, Physiology, Morphology
    • 1st Edition
    • Jean Brachet + 1 more
    • English
    The Cell: Biochemistry, Physiology, Morphology, Volume III: Meiosis and Mitosis covers chapters on meiosis and mitosis. The book discusses meiosis with regard to the meiotic behavior of chromosomes; the anomalous meiotic behavior in organisms with localized centromeres and in forms with nonlocalized centromeres; and the nature of the synaptic force. The text also describes the mechanism of crossing over; the relationship of chiasmata to crossing over and metaphase pairing; and the reductional versus equational disjunction. The process of mitosis and the physiology of cell division are also considered. The book further tackles the significance of cell division and chromosomes; the essential mitotic plan and its variants; the preparations for mitosis; and the transition period. The text also demonstrates the time course of mitosis; the mobilization of the mitotic apparatus; metakinesis; the metaphase; the mitotic apparatus; anaphase; telophase; cytokinesis; and the physiology of the dividing cell. Physiological reproduction; mitotic rhythms and experimental synchronization; and the blockage and stimulation of division are also encompassed. Biologists, microbiologists, zoologists, and botanists will find the book invaluable.

  • The Antigens

    Volume IV
    • 1st Edition
    • Michael Sela
    • English
    The Antigens, Volume IV is a comprehensive treatise covering all aspects of antigens, including their chemistry and biology as well as their immunologic role and expression. Topics covered range from the immune reactions of lipids and lipid model membranes to the immunology of antibiotics and protective antigens of bacteria. Antigens of pathogenic fungi are also explored, along with adjuvants and antigenic competition. Comprised of seven chapters, this volume begins with a review of lipids as antigens, followed by a discussion on the immunological aspects of antibiotics. The next two chapters are concerned with more complex antigens, namely, bacteria and fungi, as well as the relationship between immunity and infection. The last three chapters deal with three important areas of immunology: antigenic competition, adjuvants, and lectins. In particular, the chemistry of lectins and their application to immunology are examined. This monograph will be of interest to practitioners and researchers in immunology, experimental and clinical medicine, biochemistry, and other disciplines.

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