Life sciences print books and ebooks | Elsevier

Biochemical Disorders of the Skeleton

1st Edition
May 19, 2014
Roger K. W. Smith
English
Paperback
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eBook
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Biochemical Disorders of the Skeleton explores the biochemical and clinical aspects of skeletal disorders, including osteoporosis, osteomalacia, Paget's disease of bone, osteogenesis imperfecta, and Marfan's syndrome. Homocystinuria, Ehlers-Danlos syndrome, mucopolysaccharidose... hyperphosphatasia and hypophosphatasia, and fibrous dysplasia are also considered. Comprised of 12 chapters, this book begins with an overview of the physiology of bone, with emphasis on the structures produced by bone cells and the different hormones that influence them. The symptoms, signs, and investigation of metabolic bone disease are then described and compared. The following chapters focus on the biochemistry and clinical aspects of disorders affecting the skeleton, from osteoporosis and osteomalacia to Ehlers-Danlos syndrome, fibrous dysplasia, osteopetroses and hyperostoses, and fibrogenesis imperfecta ossium. The final chapter offers a short description of advances that have been made in understanding these biochemical disorders, including the significance of low-plasma calcitonin in women; the role of mithramycin in Paget's disease; and the identification of the different types of osteogenesis imperfecta. This monograph will be a valuable resource for physicians, pediatricians, and orthopedic surgeons.

MCQ Tutor for Students of Microbiology

1st Edition
May 12, 2014
John Gordon
English
Paperback
9 7 8 0 4 3 3 1 2 4 0 5 4
eBook
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MCQ Tutor for Students of Microbiology provides a series of multiple choice questions with annotated answers, mainly in bacteriology but also including parasitology, virology, and immunology. This book focuses on clinical applications. Organized into four parts, this book begins with an overview of the pre-clinical aspects of microbiology and host defense mechanisms. This text then deals with microbial systematics as well as the detailed properties of the various microorganisms. Other parts cover the nature and manifestation of a wide spectrum of infective diseases. This book discusses as well the laboratory diagnosis, treatment, and prevention of infective diseases. The final part deals with other examples of other forms of multiple choice question. This book is intended to be suitable for medical students in the second and third undergraduate years as an aid to preparation for their third MB examination. Students of medical and laboratory sciences as well as candidates for diploma and college examinations will also find this book useful.

Microbiology in Clinical Practice

2nd Edition
June 28, 2014
D. C. Shanson
English
Paperback
9 7 8 0 7 2 3 6 1 4 0 3 6
eBook
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Microbiology in Clinical Practice presents the infections and syndromes caused by micro-organisms. It discusses the management of infective diseases and aetiological agents. It addresses the latex agglutination, immunofluorescent, monoclonal antibody, and nucleic acid probe investigations. Some of the topics covered in the book are the classification and pathogenicity of microbes; classification of bacteria; classification of viruses; classification of fungi; general principles of antimicrobial chemotherapy; antibiotic sensitivity tests; procedures in the laboratory for microbiological diagnosis; and the mode of action of antimicrobial drugs. The resistance to antimicrobial drugs are covered. The microbiological investigations of septicaemia are discussed. The text describes the human immunodeficiency virus infection and AIDS in infants. A study of the congenital immunodeficiency and impaired resistance to infection is presented. A chapter is devoted to the predisposing factors for anaerobic infections. Another section focuses on the infections of the central nervous system. The book can provide useful information to doctors, pathologists, neurologists, students, and researchers.

The Interpretation of Ultrastructure

1st Edition
July 15, 2014
R. J. C. Harris
English
Paperback
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eBook
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The Interpretation of Ulstrastructure is a collection of papers dealing with techniques in ulstrastructural research such as in fixation, reversed staining, ultrastructure in embryos and in plants, control of observations by light microscopy, and cytochemistry at the electron microscope level. One paper describes various fixatives used on rat liver tissue including a standard osmium tetroxide solution, pure melted osmium tetroxide, and strong osmium tetroxide solutions in carbon tetrachloride. Another paper points out that the use of electron micrographs of the cell nucleus and chromosomes should include approaches to chromosome analysis. For the investigator studying the three dimensional organization of chromosomes, his approaches should include classical cytology and cytogenetics, chemical and cytochemical studies on nuclei, as well as chemical and physical analysis of nucleic acid and nucleoprotein molecules. Several papers discuss the study of natural and artificial DNA-plasma by thin sections, an assessment of negative staining techniques for revealing ultrastructure, and other approaches in the study of biological ultrastructure by high-resolution electron microscopy. The collection will benefit microbiologists, biotechnologists, and academicians connected with the biological sciences.

Imported Infectious Diseases

1st Edition
August 18, 2014
Fernando Cobo
English
Paperback
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Hardback
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eBook
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The increase of immigrant population in developed countries (mainly in Europe and North America) together with an important increase of international travel worldwide are the two most important causes that have contributed to the introduction and diagnosis of imported/tropical infectious diseases in these countries. These factors have had an important impact in developed countries in both social and economic aspects. Imported Infectious Diseases focuses not only on describing the infections, but also in evaluating the current epidemiology, the economic and social impact and the possibility to apply immunization measures and vaccines. The main purpose of this book is to give an overview of the current most important and frequent imported infectious diseases in developed countries. The first chapter informs about the medical services that are being offered to the immigrants in the main developed countries depending on the legal situation. Following chapters describe the main surveillance systems for these kinds of diseases, mainly in Europe and North America. Finally, remaining chapters contain sections on epidemiology, pathogenesis, clinical features, diagnosis, treatment and prevention.

Multiple Sclerosis and Related Disorders

1st Edition
Volume 122
February 5, 2014
Douglas S. Goodin
English
Hardback
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eBook
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Multiple Sclerosis (MS) is generally understood to be an inflammatory autoimmune disease of the central nervous system. While we still are not certain of the root cause of MS, research results suggest that unknown environmental factors and the presence of specific genes seem the most probable targets. MS causes an inflammatory response in the central nervous system leading to neurodegeneration, oligodendrocyte death, axonal damage, and gliosis. Over the past five years ongoing research has greatly expanded our understanding of the pathogenesis of MS, detailed insight into the epidemiology and genetic factors related to MS, the introduction of new technologies and tests to better diagnose and predict the future course of the disease and the introduction of new treatments targeting MS. This collection of review chapters provides a comprehensive reference into the science and clinical applications of the latest Multiple Sclerosis research and will be a valuable resource for the neuroscience research community and the clinical neurology community of researchers and practitioners.

History of Toxicology and Environmental Health

1st Edition
May 22, 2014
English
Paperback
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eBook
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Toxicology in Antiquity is the first in a series of short format works covering key accomplishments, scientists, and events in the broad field of toxicology, including environmental health and chemical safety. This first volume sets the tone for the series and starts at the very beginning, historically speaking, with a look at toxicology in ancient times. The book explains that before scientific research methods were developed, toxicology thrived as a very practical discipline. People living in ancient civilizations readily learned to distinguish safe substances from hazardous ones, how to avoid these hazardous substances, and how to use them to inflict harm on enemies. It also describes scholars who compiled compendia of toxic agents.

Protein Turnover and Lysosome Function

1st Edition
June 28, 2014
Harold L. Segal + 1 more
English
eBook
9 7 8 1 4 8 3 2 2 0 1 9 2

Protein Turnover and Lysosome Function comprises the proceedings of a symposium under the same title held at the State University of New York at Buffalo on August 21-26, 1977. The book discusses mechanisms of protein turnover, as well as the identification and characterization of intracellular proteases. The text also describes the internalization of macromolecules into the intracellular digestive system; the types of specificity entailed; and the fate of the membrane material involved in the vacuolization process. Biochemists, pathologists, cell biologists, molecular biologists, and physiologists will find the book invaluable.

The Biological Clock

1st Edition
June 28, 2014
Frank A. Brown + 2 more
English
Paperback
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eBook
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The Biological Clock describes the rhythmic processes in a great variety of plants and animals. This book is an outgrowth of the 1969 James Arthur Lecture Series on "Time and its Mysteries" held at New York University. This three-chapter work begins with the basic principles of biological rhythms and clocks, along with various diagrams to illustrate some aspects of circadian rhythms in animals. The second chapter discusses the hypothesis of environmental timing of the clock. This chapter explores numerous research studies on phenomenon of biological rhythms, the nature of the rhythmic mechanism, and hormonal regulation. The third chapter examines the cellular-biochemical clock hypothesis and its contribution in the progress of understanding the complexity of biological rhythm. This book is intended primarily for biologists, behaviorists, and researchers.

Governing Nano Foods: Principles-Based Responsive Regulation

1st Edition
January 13, 2014
Bernd van der Meulen + 5 more
English
Paperback
9 7 8 0 1 2 4 2 0 1 5 6 9
eBook
9 7 8 0 1 2 4 2 0 2 1 4 6

Food which nanotechnology has impacted or to which nanotechnology is applied is referred to as nanofood. From treatment of the soil in which a crop plant is grown to the caring of a food, nanotechnology is a growing factor in the food supply. At this point, however, there is no definitive, effective global method for regulating the use of nanotechnology as it relates to the food suply. Legislation on nanotechnologies is still evolving, as is understanding what data is needed for effective, efficient and appropriate risk assessment associated with nanotechnology impacted foods. Due to the emerging nature of nanotechnology and its role in the food supply, case-by-case studies are the current norm, but the need for wide-scale testing and broad-based regulatory standards is urgent. This project is based on an EFFoST study designed to provide a comparative study of nanofood regulations in order to guide regulation development in this rapidly expanding market.

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