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    • Encyclopedia of Toxicology

      • 3rd Edition
      • March 24, 2014
      • Philip Wexler
      • English
      • Hardback
        9 7 8 0 1 2 3 8 6 4 5 4 3
      • Hardback
        9 7 8 0 1 2 3 8 6 4 5 5 0
      The third edition of the Encyclopedia of Toxicology, Four Volume Set presents entries devoted to key concepts and specific chemicals, and is updated to reflect current advances in the field. It contains new information on nanotoxicology, epigenetics, persistent organic pollutants, computational toxicology and bioinformatics, controversial chemicals, and much more. Along with the traditional scientific entries, new articles focus on worldwide initiatives, the potential health and environmental effects of new technologies, and the societal implications of global legal and regulatory issues. With thoroughly updated articles, references, and resources for recommended reading, the third edition has been expanded in length, breadth, and depth, and continues to provide an extensive overview of the many facets of toxicology.

    • Immunology in Clinical Medicine

      • 3rd Edition
      • May 12, 2014
      • J. L. Turk
      • English
      • Paperback
        9 7 8 0 4 3 3 3 2 8 5 2 0
      • eBook
        9 7 8 1 4 8 3 1 8 3 0 3 9
      Immunology in Clinical Medicine is an introduction to immunology in clinical medicine, with emphasis on immunological concepts underlying disease processes. The effect of drugs known to suppress immunological processes are considered especially in relation to whether they operate by really suppressing immunological processes or whether they have other actions. Comprised of 17 chapters, this book begins with an overview of the nature of the immune response, followed by a discussion on reactionS in the tissues mediated by humoral antibodies. The reader is then introduced to reactions in the tissues caused by the cell-mediated immune response; immunological processes in infective diseases; and the concept of autoimmunity and its relation to disease. Subsequent chapters focus on the immunology of diseases such as cancer, skin diseases, connective tissue diseases, and diseases of the intestinal tract, respiratory tract, liver, and amyloidosis. The final chapter is devoted to the role of the clinical immunologist in patient care and therapy. This monograph is intended for students and practitioners of clinical medicine.

    • Atlas of Chick Development

      • 3rd Edition
      • May 19, 2014
      • Ruth Bellairs + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 3 8 4 9 5 1 9
      • eBook
        9 7 8 0 1 2 3 8 4 9 5 2 6
      The Atlas of Chick Development, Third Edition, a classic work covering all major event of chick development, is extensively updated with new and more detailed photographs, enlargements showing regions of special-interest and complexity, and new illustrations. The revised text and expanded illustrative material describe the intricate changes that take place during development, together with accounts of recent experimental and molecular research that has transformed our understanding of morphogenesis. These wide-ranging updates make this book an essential resource for developmental biologists, geneticists, molecular biologists, poultry scientists, biochemists, immunologists, and other life scientists who use the chick embryo as their research model. Individuals joining this burgeoning area, ignited by the increased insight into events surrounding organ and tissue differentiation, will find this a valuable tool to help grow a basic knowledge of morphogenesis.

    • Catecholamines and Schizophrenia

      • 1st Edition
      • May 18, 2014
      • Steven W. Matthysse + 1 more
      • English
      • Hardback
        9 7 8 0 0 8 0 1 8 2 4 2 1
      • Paperback
        9 7 8 1 4 8 3 1 2 7 1 5 6
      • eBook
        9 7 8 1 4 8 3 1 5 9 5 7 7
      Catecholamines and Schizophrenia reviews research linking catecholamines to schizophrenia. Topics include the relationship between stereotyped behavior and amphetamine psychosis, between antipsychotic drugs and catecholamine synapses, and between biogenic amines and behavior. The chemical neuropathology of schizophrenia, enzymology and regulation of catecholamine enzymes, and advances in histochemical technologies used in neurochemical pathology are also covered. This book consists of 47 chapters organized into six sections. After giving an overview of the pharmacology and physiology of stereotyped behavior, this book discusses the behavioral and biochemical aspects of amphetamine psychosis; stereoselective features of catecholamine disposition and their behavioral implications; and the effects of amphetamines on catecholamine metabolism. A two-factor theory of schizophrenia is also presented. The chapters that follow focus on the role of monoamine oxidase in schizophrenia and other behavioral disorders; the chemical pathology of schizophrenia; genetic control of biogenic amines; and dopamine-beta-hydrox... This book will be of value to students, researchers, and practitioners in fields ranging from neuropharmacology and physiology to biology, biochemistry, psychiatry, and psychology.

    • Current Topics in Bioenergetics

      • 1st Edition
      • June 28, 2014
      • D. Rao Sanadi
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 3 4 7 8
      • eBook
        9 7 8 1 4 8 3 2 1 6 9 0 4
      Current Topics in Bioenergetics, Volume 6 provides information pertinent to the phenomenon of energy transduction. This book covers a wide variety of topics, including photosynthesis, muscle contraction, transport across membranes, and oxidative phosphorylation. Organized into six chapters, this volume begins with an overview of the solute transport functions of membrane vesicles from kidney and intestine. This text then examines the specialized calcium transport system of mitochondria from both mechanistic and biological viewpoints. Other chapters consider the energy-transducing mechanisms in bacteria and chromoplast from the standpoint of mechanism. This book discusses as well ionophores and channel formers as powerful tools in the study of membrane function. The final chapter deals with the metabolic link between fundamental cell physiological events, such as hormonal perturbation of metabolism and cell development, on the one hand, and an altered ability of mitochondria to transport Ca2+, on the other. This book is a valuable resource for bioenergeticists, biochemists, biologists, and microbiologists.

    • Monoclonal Antibodies Against Bacteria

      • 1st Edition
      • May 10, 2014
      • Alberto J. L. Macario + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 3 0 4 7
      • eBook
        9 7 8 1 4 8 3 2 5 7 3 9 6
      Monoclonal Antibodies Against Bacteria, Volume III covers the basis for understanding developments of practical importance in the health sciences within the area of microbiology and infectious diseases, focusing on advances made possible by monoclonal antibodies. This 12-chapter volume specifically considers the basic principles of hybridoma technology. The introductory chapters deal with treponemal antigens of significance for understanding syphilis, yaws, pinta, salmonellosis, and other gastroenteropathies. The subsequent chapters highlight pediatric infections and the strategies for molecular analyses of bacterial antigens, focusing on cell walls, S layers, and sheaths. The remaining chapters examine the bacterial toxins involved in gaseous gangrene and other forms of cell damage, such as diphtheria, caries and periodontal diseases, and bacteria relevant to animal sciences. This book will prove useful to internists, pediatricians, surgeons, dentists, veterinarians, clinical pathologists, and laboratory technologists.

    • Brain Metastases from Primary Tumors, Volume 2

      • 1st Edition
      • December 30, 2014
      • M. A. Hayat
      • English
      • Hardback
        9 7 8 0 1 2 8 0 1 4 1 9 6
      • eBook
        9 7 8 0 1 2 8 0 1 6 8 9 3
      Brain metastases are the most common malignant tumors of the central nervous system, yet their incidence appears to be increasing in spite of the advancement of cancer therapies. While much is known about primary cancers (including primary brain tumors), less work has been done to uncover the roots of metastatic disease. Brain Metastases from Primary Tumors fills that gap, serving as the first two-part reference to focus primarily on the link between primary cancers and brain metastases. This link is explored for the most common cancer types – lung, breast, and melanoma. Additionally, biological background as well as therapy for CNS metastases is addressed. Age- and gender-related trends are also discussed, as is the use of biomarkers for early detection.

    • Clinical Immunobiology

      • 1st Edition
      • Volume 2
      • June 28, 2014
      • Fritz H. Bach + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 2 9 0 7
      • eBook
        9 7 8 1 4 8 3 2 1 6 3 3 1
      Clinical Immunobiology, Volume 2 covers the advances in the field being made to apply bone marrow transplantation to the treatment of several diseases. This volume is divided into 11 chapters and begins with surveys of the clinical considerations of bone marrow transplantation. Considerable chapters are devoted to the application of this transplantation to the treatment of various diseases, including aplastic anemia, aregenerative pancytopenia, leukemia, uniformly fatal severe combined immunodeficiency diseases, and Wiskott-Aldrich syndrome. Other chapters examine the cellular engineering in the form of bone marrow and thymus transplantation. The remaining chapters consider the effects of exposure to excessive amounts of radiation or cytotoxic chemicals, as well as the hematopoietic failure based on malfunction of the complex process of normal hematological development and maintenance. This book will be of great value to clinical immunobiologists, practicing physicians, researchers, and medical and biology students.

    • Cancer

      • 1st Edition
      • March 1, 2014
      • Victor R Preedy
      • English
      • Paperback
        9 7 8 0 1 2 8 1 0 2 6 7 1
      • Hardback
        9 7 8 0 1 2 4 0 5 2 0 5 5
      • eBook
        9 7 8 0 1 2 4 0 5 5 2 4 7
      Cancer: Oxidative Stress and Dietary Antioxidants bridges the trans-disciplinary divide and covers in a single volume the science of oxidative stress in cancer and then the potentially therapeutic usage of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are described in concert with other processes such as apoptosis, cell signaling, and receptor mediated responses. This approach recognizes that diseases are often multifactorial and that oxidative stress is a single component of this. Oncologists, cancer researchers, and nutritionists are separated by divergent skills and professional disciplines that need to be bridged in order to advance preventative as well as treatment strategies. While oncologists and cancer researchers may study the underlying pathogenesis of cancer, they are less likely to be conversant in the science of nutrition and dietetics. On the other hand, nutritionists and dietitians are less conversant with the detailed clinical background and science of oncology. This book addresses this gap and brings each of these disciplines to bear on the processes inherent in the oxidative stress of cancer.

    • Guide des analyses en immunologie

      • 1st Edition
      • May 20, 2014
      • Collège des Enseignants d'Immunologie
      • French
      • eBook
        9 7 8 2 2 9 4 7 4 1 6 0 9
      Ce guide, rédigé par l'ASSIM recense les principales analyses en immunologie prises en charge par la Sécurité sociale dans le cadre de la Nomenclature des Actes de Biologie Médicale (NABM).L'ouvrage développe en 6 grandes parties l'exploration : - de l'auto-immunité ; - de l'immunité humorale ; - de l'immunité cellulaire ; - en histocompatibilité et l'étude des associations HLA-maladies ; - des traitements par biomédicaments immunologiques. Chacune de ces parties est détaillée de façon pratique et synthétique sous forme de fiches, étayées de synopsis d'aide à l'exploration de la pathologie. Les points suivants sont systématiquement abordés : - la signification biologique du paramètre ; - les objectifs de l'analyse ; - la place de cette analyse dans un bilan d'exploration ; - la nature du prélèvement ; - les recommandations particulières ; - les contraintes d'acheminement ; - le mode de conservation ; - le principe méthodologique ; - le type de méthode et de mesure ; - le contrôle interne et l'évaluation externe de la qualité ; - les performances du test ; - les causes d'erreur et les limites du test.

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Toxicology