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Books in Life sciences

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    • The Comprehensive Sourcebook of Bacterial Protein Toxins

      • 4th Edition
      • May 29, 2015
      • Joseph E. Alouf + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 0 1 8 8 2
      • eBook
        9 7 8 0 1 2 8 0 0 5 8 9 7
      The Comprehensive Sourcebook of Bacterial Protein Toxins, Fourth Edition, contains chapters written by internationally known and well-respected specialists. This book contains chapters devoted to individual toxins, as well as chapters that consider the different applications of these toxins. Considerable progress has been made in understanding the structure, function, interaction and trafficking into cells, as well as mechanism of action of toxins. Bacterial toxins are involved in the pathogenesis of many bacteria, some of which are responsible for severe diseases in human and animals, but can also be used as tools in cell biology to dissect cellular processes or used as therapeutic agents. Novel recombinant toxins are already proposed in the treatment of some diseases, as well as new vaccines. Alternatively, certain toxins are also considered as biological weapons or bioterrorism threats. Given the multifaceted aspects of toxin research and the multidisciplinary approaches adopted, toxins are of great interest in many scientific areas from microbiology, virology, cell biology to biochemistry and protein structure. This new edition is written with a multidisciplinary audience in mind and contains 5 new chapters that reflect the latest research in this area. Other chapters have been combined, deleted and fully revised as necessary to deliver relevant and valuable content.

    • Laterality

      • 1st Edition
      • December 22, 2015
      • Clare Porac
      • English
      • Paperback
        9 7 8 0 1 2 8 0 1 2 3 9 0
      • eBook
        9 7 8 0 1 2 8 0 1 3 5 7 1
      Left-handedness has been connected to many different conditions, traits, and abilities. This is especially true for pathological syndromes, such as schizophrenia, along with learning disabilities and autism. The published research on handedness is vast and frequently contradictory, often raising more questions than providing answers. Questions such as: Is handedness genetic? Can handedness be changed? Are there consequences to training someone to switch handedness? Are there positive traits associated with left-handedness like creativity? Are there negative traits associated with left-handedness like trouble reading maps? Is it abnormal to do some things right-handed and other things left-handed? Are the brains of left-handers different from the brains of right-handers? Laterality: Exploring the Enigma of Left-Handedness examines the research conducted over the past 50 years with special emphasis on twenty-first century research on handedness and translates this literature into an accessible and readable form. Each chapter is based on a question or questions covering diverse topics such as genetic and biological origins of handedness, familial and hormonal influences on handedness, and the effects of a majority right-handed world on the behaviors of left-handers.

    • La maladie de Parkinson

      • 3rd Edition
      • March 13, 2015
      • Luc Defebvre + 1 more
      • French
      • eBook
        9 7 8 2 2 9 4 7 4 4 2 3 5
      La maladie de Parkinson est, après la maladie d'Alzheimer, l'affection neurologique la plus répandue au sein de la population après 50 ans. Elle touche près de 2 % des personnes de plus de 65 ans. Ce pourcentage augmentant avec l'âge, on peut prévoir qu'avec le vieillissement de la population, le nombre de patients ne cessera d'augmenter dans les années à venir. La troisième édition de cet ouvrage, entièrement en couleurs, consacrée à la maladie de Parkinson rend compte de façon didactique des avancées de ces cinq dernières années, en abordant de façon exhaustive tous les aspects de cette pathologie : l'épidémiologie, l'étiopathogénie, les aspects génétiques, la physiopathologie, les signes moteurs et non moteurs, notamment les troubles cognitifs, psychiques et comportementaux. De nouveaux chapitres dédiés aux troubles psychiatriques et du comportement, à l'éducation thérapeutique, les biothérapies, la neuropathologie et la procédure de reconnaissance comme maladie professionnelle viennent compléter cette monographie. Dans cet ouvrage, sont également mis à jour les critères diagnostiques, les échelles et questionnaires d'évaluation, la place de l'imagerie morphologique et fonctionnelle enfin les stratégies thérapeutiques actuelles : médicamenteuses, chirurgicales, rééducatives et orthophoniques.

    • Laboratory Methods in Enzymology: Protein Part D

      • 1st Edition
      • Volume 559
      • June 9, 2015
      • English
      • Hardback
        9 7 8 0 1 2 8 0 0 2 7 9 7
      • eBook
        9 7 8 0 1 2 8 0 0 3 3 5 0
      The critically acclaimed laboratory standard for almost 50 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Each volume is eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 520 volumes and 40,000 chapters in the collection, much of the material is still relevant today and is truly an essential publication for researchers in all fields of life sciences, including microbiology, biochemistry, cancer research, and genetics, just to name a few. In this volume, number 545, we have brought together a number of core protocols concentrating on protein, carefully written and edited by experts.

    • Epigenetic Gene Expression and Regulation

      • 1st Edition
      • October 19, 2015
      • Suming Huang + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 7 9 9 9 5 8 6
      • eBook
        9 7 8 0 1 2 8 0 0 4 7 1 5
      Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples.

    • Zoonotic Viruses of Northern Eurasia

      • 1st Edition
      • May 25, 2015
      • Dimitry Konstantinovich Lvov + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 1 7 4 2 5
      • eBook
        9 7 8 0 1 2 8 0 1 8 4 4 6
      Zoonotic Viruses of Northern Eurasia: Taxonomy and Ecology provides a review of modern data of the taxonomy, distribution, and ecology of zoonotic viruses in the ecosystems of Northern Eurasia. With climate changes, increasing population density of arthropod vectors and vertebrate hosts, development of unused lands, transferences of viruses by birds, bats, infected humans, and animals, vectors allow virus populations to adapt to the new environment. This leads to the appearance of emerging or re-emerging infections. This book presents data about circulation and evolution of influenza viruses, tick-borne encephalitis virus, West Nile virus, Crimean-Congo hemorrhagic fever virus, hantaviruses, Sindbis virus, California encephalitis group viruses and other pathogenic viruses as well as of novel viruses classified for the first time using next-generation sequence.

    • Early Vascular Aging (EVA)

      • 1st Edition
      • August 6, 2015
      • Michael Hecht Olsen + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 1 3 8 7 8
      • eBook
        9 7 8 0 1 2 8 0 1 6 7 6 3
      Early Vascular Aging (EVA): New Directions in Cardiovascular Protection brings together the last decade of research related to the characterization of EVA, as well as the predictive power of pulse wave velocity (PWV). The book presents a novel approach to the problem of cardiovascular disease, showing it in relation to great vessels disease and revealing a comprehensive approach to the problem of increased rigidity of the great vessels, its causes, and further consequences. Information provided is accompanied by online access to a supplemental website with video clips of anatomic specimens, cardiac imaging, and surgical procedures.

    • Aquafeed Formulation

      • 1st Edition
      • October 9, 2015
      • Sergio F Nates
      • English
      • Hardback
        9 7 8 0 1 2 8 0 0 8 7 3 7
      • eBook
        9 7 8 0 1 2 8 0 0 9 9 5 6
      Aquafeed Formulation is the only resource that provides summaries with examples and formulation techniques specifically to meet the needs of anyone in the aquaculture industry. As feed is the largest single cost item in aquaculture production, and formulating aquaculture feed requires many combinations of several ingredients and nutrient requirements, this book takes a clear-and -concise approach, providing essential information on formulation and covering relevant available software, feed nutrients, and additives such as enzymes and phytase and conjugated fatty acids, as well as best industry practices to improve aquafeed production. Users will find this to be a one-stop resource for anyone interested or involved in, the global aquaculture industry.

    • Cannabinoids in Neurologic and Mental Disease

      • 1st Edition
      • January 21, 2015
      • Liana Fattore
      • English
      • Hardback
        9 7 8 0 1 2 4 1 7 0 4 1 4
      • eBook
        9 7 8 0 1 2 4 1 7 1 2 4 4
      The application of cannabis sativa for the treatment of neurologic and mental disease is expanding. Cannabinoids in Neurologic and Mental Disease collects and presents for the first time recent research involving the use of pharmacological cannabinoids for the treatment of neurodegenerative and neuroinflammatory disease. The neurologic application of cannabinoid therapy builds upon psychiatric and psychological use for the treatment of a variety of core mental disorders. This comprehensive reference on the known uses of cannabinoids will be useful for clinical neurologists, neuroscience and clinical neuroscience researchers, clinical psychologists and psychiatrists and the general medical community.

    • Atlas of Early Zebrafish Brain Development

      • 2nd Edition
      • November 18, 2015
      • Dr. Thomas Mueller + 1 more
      • English
      • eBook
        9 7 8 0 1 2 4 1 7 2 8 6 9
      Atlas of Early Zebrafish Brain Development: A Tool for Molecular Neurogenetics, Second Edition, remains the only neuroanatomical expression atlas of important genetic and immunohistochemical markers of this vertebrate model system. It represents a key reference and interpretation matrix for analyzing expression domains of genes involved in Zebrafish brain development and neurogenesis, and serves as a continuing milestone in this research area. This updated volume provides in-situ hybridized and immunostained preparations of complete series of brain sections, revealing markers of the fundamental stages in the life history of neuronal cells in very high quality preparations and photographic plates. Specific additions to this edition include documentation on the distribution of neurons expressing GABA, dopamine and serotonin, material on the basal ganglia, hypothalamus, and the caudal, segmented part of the diencephalon, new theories on the early organization of the telencephalon and thalamus, and integration of a comparative perspective on the mid- and hindbrain.

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