Books in Life sciences

The Use of CRISPR/cas9, ZFNs, TALENs in Generating Site-Specific Genome Alterations

1st Edition
Volume 546
November 4, 2014
Jennifer A. Doudna + 1 more
English
Hardback
9 7 8 0 1 2 8 0 1 1 8 5 0
eBook
9 7 8 0 1 2 8 0 1 3 3 4 2

This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers recent research and methods development for changing the DNA sequence within the genomes of cells and organisms. Focusing on enzymes that generate double-strand breaks in DNA, the chapters describe use of molecular tools to introduce or delete genetic information at specific sites in the genomes of animal, plant and bacterial cells.

Biomaterials and Medical Device - Associated Infections

1st Edition
November 4, 2014
L Barnes + 1 more
English
Hardback
9 7 8 0 8 5 7 0 9 5 9 7 8
eBook
9 7 8 0 8 5 7 0 9 7 2 2 4

Despite advances in materials and sterilisation, patients who receive biomaterials of medical device implants are still at risk of developing an infection around the implantation site. This book reviews the fundamentals of biomaterials and medical device related infections and methods and materials for the treatment and prevention of infection. The first part of the book provides readers with an introduction to the topic including analyses of biofilms, diagnosis and treatment of infection, pathology and topography. The second part of the book discusses a range of established and novel technologies and materials which have been designed to prevent infection.

Handbook of Natural Antimicrobials for Food Safety and Quality

1st Edition
November 4, 2014
M Taylor
English
Paperback
9 7 8 0 0 8 1 0 1 3 9 9 1
eBook
9 7 8 1 7 8 2 4 2 0 4 2 2

Natural additives are increasingly favoured over synthetic ones as methods of ensuring food safety and long shelf-life. The antimicrobial properties of both plant-based antimicrobials such as essential oils and proteins such as bacteriocins are used in, for example, edible preservative films, in food packaging and in combination with synthetic preservatives for maximum efficacy. New developments in delivery technology such as nanoencapsulation also increase the potential of natural antimicrobials for widespread use in industry. Part one introduces the different types of natural antimicrobials for food applications. Part two covers methods of application, and part three looks at determining the effectiveness of natural antimicrobials in food. Part four focuses on enhancing quality and safety, and includes chapters on specific food products.

Coffee in Health and Disease Prevention

1st Edition
November 3, 2014
Victor R Preedy
English
Hardback
9 7 8 0 1 2 4 0 9 5 1 7 5
eBook
9 7 8 0 1 2 4 1 6 7 1 6 2

Coffee in Health and Disease Prevention presents a comprehensive look at the compounds in coffee, their reported benefits (or toxicity risks) and also explores them on a health-condition specific level, providing researchers and academics with a single-volume resource to help in identifying potential treatment uses. No other book on the market considers all the varieties of coffee in one volume, or takes the disease-focused approach that will assist in directing further research and studies. The book embraces a holistic approach and effectively investigates coffee and its specific compounds from the biochemical to the nutritional well-being of geographical populations. This book represents essential reading for researchers in nutrition, dietetics, food science, biochemistry, and public health.

Implantable Electronic Medical Devices

1st Edition
October 31, 2014
Dennis Fitzpatrick
English
Paperback
9 7 8 0 1 2 4 1 6 5 5 6 4
eBook
9 7 8 0 1 2 4 1 6 5 7 7 9

Implantable Electronic Medical Devices provides a thorough review of the application of implantable devices, illustrating the techniques currently being used together with overviews of the latest commercially available medical devices. This book provides an overview of the design of medical devices and is a reference on existing medical devices. The book groups devices with similar functionality into distinct chapters, looking at the latest design ideas and techniques in each area, including retinal implants, glucose biosensors, cochlear implants, pacemakers, electrical stimulation therapy devices, and much more. Implantable Electronic Medical Devices equips the reader with essential background knowledge on the application of existing medical devices as well as providing an introduction to the latest techniques being used.

Evolutionary Origins and Early Development of Number Processing

1st Edition
Volume 1
October 31, 2014
David C. Geary + 2 more
English
Hardback
9 7 8 0 1 2 4 2 0 1 3 3 0
eBook
9 7 8 0 1 2 8 0 0 8 8 8 1

The first volume in this ground-breaking series focuses on the origins and early development of numerical cognition in non-human primates, lower vertebrates, human infants, and preschool children. The text will help readers understand the nature and complexity of these foundational quantitative concepts and skills along with evolutionary precursors and early developmental trajectories.

Control of Plant Virus Diseases

1st Edition
Volume 90
October 31, 2014
Gad Loebenstein + 1 more
English
Hardback
9 7 8 0 1 2 8 0 1 2 4 6 8
eBook
9 7 8 0 1 2 8 0 1 2 6 4 2

The first review series in virology and published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews, providing a valuable overview of the field. The series of eclectic volumes are valuable resources to virologists, microbiologists, immunologists, molecular biologists, pathologists, and plant researchers. Volume 90 features articles on control of plant virus diseases.

Brain Extracellular Matrix in Health and Disease

1st Edition
Volume 214
October 30, 2014
Alexander Dityatev + 2 more
English
Hardback
9 7 8 0 4 4 4 6 3 4 8 6 3
eBook
9 7 8 0 4 4 4 6 3 4 9 4 8

In the central nervous system, extracellular matrix (ECM) molecules, including hyaluronic acid, chondroitin and heparan sulfate proteoglycans, tenascins, reelin and agrin, along with their remodelling enzymes, such as neurotrypsin, neuropsin, plasminogen activators, and metalloproteinases, are secreted by neural and non-neural cells into the extracellular space to form the ECM and signal via ECM receptors. Despite recent advances in the ECM field, the importance of neural ECM for physiological and pathological processes is currently less widely recognized than that of other CNS elements. This book will enlighten recent progress in our understanding of mechanisms by which neural ECM, its receptors and activity-dependent ECM remodeling regulate neural development, synaptic plasticity, and contribute to pathological changes in the brain. In the first part, the roles of ECM signaling and proteolytic modification of ECM in neurogenesis, neural migration, axonal pathfinding, synaptogenesis, synaptic and homeostatic plasticity will be discussed. The second part will focus on the emerging ECM-dependent mechanisms associated with CNS injury, epilepsy, neurodegenerative and neuropsychiatric diseases. For further development of neural ECM field, a very important contribution is the third part of the book, which is devoted to neural ECM-targeting tools and therapeutics. The concluding fourth part will highlight advances in development of artificial ECM and ECM-based systems suitable for multisite recording and stimulation of neural cells.

The History of the Gamma Knife

1st Edition
Volume 215
October 30, 2014
Jeremy C. Ganz
English
Hardback
9 7 8 0 4 4 4 6 3 5 2 0 4
eBook
9 7 8 0 4 4 4 6 3 5 2 6 6

The History of the Gamma Knife presents the evolution of concepts and technology which ended in the production of the modern Gamma Knife. The story starts before the Second World War and links pioneers in Berkeley and Sweden. To the best of the author’s belief it is the first detailed, factually accurate account of the development of this important therapeutic method.

Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease

5th Edition
October 28, 2014
Roger N. Rosenberg + 1 more
English
eBook
9 7 8 0 1 2 4 1 0 5 4 9 2

Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format. Previous editions have established this book as the leading tutorial reference on neurogenetics. Researchers will find great value in the coverage of genomics, animal models and diagnostic methods along with a better understanding of the clinical implications. Clinicians will rely on the coverage of the basic science of neurogenetics and the methods for evaluating patients with biochemical abnormalities or gene mutations, including links to genetic testing for specific diseases.

Related subjects

Agricultural and biological sciences

Drug discovery

Immunology

Microbiology and virology

Neuroscience

Pharmaceutical sciences

Pharmacology

Toxicology

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health