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Elsevier

Books in Life sciences

  • Histone Deacetylases in Neurodegenerative Disease Part B

    • 1st Edition
    • Volume 734
    • English
    Histone Deacetylases in Neurodegenerative Disease, Part B, Volume 734 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on timely topics surrounding the Interaction of HDAC6 ZnF UBP with Tau affects its stability by NMR and Simulation studies, Protocols for In Vitro Analysis of Liquid-Liquid Phase Separation of Proteins, Histone deacetylases in NS, Histone Deacetylase 6 ZnF UBP domain enhances podosome formation in neuronal cells studied by high-resolution confocal microscopy, Methodological approach to Investigate Peroxiredoxin 1 Deacetylation by Histone Deacetylase 6, Critical structural features of HDAC11 inhibitors, and much more.Additional chapters in this release include Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration, Elucidation of Site-Specific Ubiquitination on Chaperones in Response to Mutant Huntingtin, Protein acetylation dynamics (histone and non-histone) and role protein deacetylases in disease, Epigenetic Clues: Predicting Maternal Depression Through DNA Methylation, A short guide on in vivo transfection of flag-HDAC4 in dentate gyrus for study of adult neurogenesis in brain trauma, Decoding the Acetylation Journey from Neural Crest to Melanocyte, and more.

  • Artificial Intelligence for Enhanced Diagnosis in Oncology

    • 1st Edition
    • Gowhar Rashid + 3 more
    • English
    “Artificial Intelligence for Enhanced Diagnosis in Oncology” explores the transformative role of AI in cancer care, examining its applications across various domains. The book introduces key AI technologies, such as machine learning and natural language processing, and discusses the challenges and opportunities they present in oncology. Each chapter focuses on specific areas where AI has significant impact, including early cancer screening, diagnosis, pathology, surgical oncology, and imaging. Readers will learn how AI improves precision in treatment, optimizes clinical trial designs, and accelerates drug discovery while addressing critical issues like predicting adverse drug reactions and assessing cancer risks. Emphasizing personalized oncology, the book also highlights innovative approaches to patient education and engagement. Concluding with insights on emerging trends and ethical considerations, this resource is essential for researchers, clinicians, and healthcare professionals committed to advancing cancer care through AI technologies.

  • Radiation Spectrum and Plant Metabolism

    Interactions from the Subcellular to the Ecosystem Level
    • 1st Edition
    • Sumira Jan + 1 more
    • English
    Radiation Spectrum and Plant Metabolism brings together advances in photobiology, biophysics, and metabolite chemistry to illuminate how light shapes plant structure, function, and ecological performance. The volume follows the pathways through which radiation interacts with plant systems, offering an integrated perspective that links subcellular processes to whole‑plant behavior and ecosystem dynamics.Covering the full breadth of plant–light relationships, the book examines the optical properties of leaf tissues, the coordination of photoreceptors and pigments, and the metabolic networks through which plants interpret spectral cues. It outlines how shifts in light quality influence development, stress responses, and the production of secondary metabolites, providing a mechanistic foundation for understanding plant adaptability under both natural and controlled environments.As climate change alters terrestrial and cosmic radiation patterns, a comprehensive view of plant responses has become increasingly critical. This reference resource synthesizes emerging insights into changing spectral regimes, their biochemical and physiological consequences, and the broader implications for plant fitness, crop resilience, and phyllosphere interactions. Later chapters connect these concepts to applied practice, highlighting innovations in horticultural lighting technologies and the measurement techniques that support precision light management.Designed for researchers and advanced practitioners across the plant sciences, this volume offers a rigorous framework for interpreting how variable radiation environments shape biological systems and the metabolic processes that sustain them.

  • Autophagy – Part B

    • 1st Edition
    • Volume 404
    • English
    Autophagy Part B provides an in-depth exploration of advanced mechanisms, functions, and roles of autophagy in health and disease. This volume features contributions from leading experts, covering recent developments in autophagy research, its implications in cellular homeostasis, neurodegeneration, cancer, immunity, and therapeutic strategies. Designed for researchers, clinicians, and students, the book offers valuable insights into the complexities and applications of autophagy in modern biomedical science.

  • Human Microbiome and their Implications for Oncological Diagnosis and Treatment

    A Handbook for Clinicians and Researchers
    • 1st Edition
    • Mohammad Akram
    • English
    Human Microbiome and their Implications for Oncological Diagnosis and Treatment; A Handbook for Clinicians and Researchers explores the crucial role of the human microbiome in oncology. The book aims to provide a thorough understanding of microbiome-oncology interactions by compiling diverse perspectives and insights into existing research findings and methodologies. It addresses the need for a comprehensive educational resource tailored to the needs of clinicians and researchers. Contributed by leading experts, it examines the multifaceted roles, diagnostic potential, and therapeutic implications of the microbiome in cancer.Readers will find an in-depth look at microbiome-oncology interactions, addressing microbial dysbiosis, diagnostic biomarkers, therapeutic interventions, and emerging research trends. The handbook provides practical insights, clinical guidelines, and fosters interdisciplinary collaboration to advance the field of oncology to clinicians, researchers, educators, and students seeking up-to-date information on the role of the human microbiome in cancer.

  • Brain Energy Metabolism in Alzheimers Disease - Part C

    • 1st Edition
    • Volume 188
    • English
    Brain Energy Metabolism in Alzheimer’s Disease – Part C, Volume 188 in the International Review of Neurobiology series, presents the latest research on metabolic dysfunction and its role in neurodegenerative diseases. This volume brings together contributions from an international panel of experts, exploring the molecular, cellular, and systemic aspects of energy metabolism in Alzheimer’s disease and related disorders.Chapters in this release examine metabolic therapeutic targets in Alzheimer’s disease, alterations in brain energy metabolism in comparison with Parkinson’s disease, and the role of epigenetic modulation through natural compounds. Additional sections address mitochondrial dysfunction, disruption of metabolic pathways, and the contribution of glial cells to neurodegenerative processes.Further contributions explore metabolic disorders linked to Parkinson’s disease, signaling pathways in neurodegeneration, and advances in therapeutic and diagnostic strategies targeting key enzymes. The volume also highlights the role of intestinal microbiota, nanocarrier-based therapeutic approaches, and emerging treatments such as HDAC inhibitors. Together, these chapters provide a comprehensive overview of the mechanisms, biomarkers, and therapeutic prospects related to energy metabolism in neurodegenerative diseases, making this volume an essential reference for researchers and clinicians in neuroscience and neurobiology.

  • Microbiome in Head and Neck Cancer: Pathogenesis, Diagnosis and Therapeutic Implications

    Part A
    • 1st Edition
    • Volume 169
    • English
    Microbiome in Head and Neck Cancer: Pathogenesis, Diagnosis and Therapeutic Implications, Volume 169 in the Advances in Immunology series, presents an authoritative exploration on how microbial communities contribute to the initiation, progression, and treatment of head and neck cancers. Chapters highlight The Microbiome of the Head and Neck Region, Overview Head and Neck Microbiota and the Factors Influencing the Head and Neck Microbiome, Mechanistic Pathways of Dysbiosis in Cancer Development, Oral Microbiota and OPMDs, Oral Potentially Malignant Disorders (OPMDs): An Overview, Oral Microbiota and Oral Cancer, Oral Squamous Cell Carcinoma (OSCC): An Overview, and much more.Additional chapters cover the Role of the Oral Microbiome in Oral Cancer (OSCC), Microbiome as a Prognostic Indicator in Oral Cancer, Diagnostic and Therapeutic Applications, Microbiome-Based Diagnostic Approaches, Modulating the Head and Neck Microbiome for Cancer Prevention, Microbiome-Targeted Therapeutics in Head and Neck Cancer, Artificial Intelligence in Microbiome Data Analysis: Applications in Head and Neck Cancer, and Challenges and Future Directions in Head & Neck Microbiome Research.

  • Cell Death Part B

    • 1st Edition
    • Volume 206
    • English
    Cell Death Part B continues the comprehensive exploration of cellular mechanisms governing the fate of cells in health and disease. This volume delves deeper into the molecular pathways, regulatory networks, and biological consequences of various cell death modalities, including apoptosis, necrosis, autophagy, ferroptosis, pyroptosis, and other emerging forms.

  • AI and Data Science in Precision Medicine, Predictive Analytics, and Medical Practice

    • 1st Edition
    • Olfa Boubaker + 1 more
    • English
    AI and Data Science in Precision Medicine, Predictive Analytics, and Medical Practice examines the transformative role of AI and data science in improving diagnosis, treatment, and healthcare delivery. It shows how machine learning, deep learning, and advanced signal and image analysis enable breakthroughs in genomics, multi-omics integration, biomedical imaging, EEG-based seizure prediction, and real-time physiological monitoring. The book highlights AI-driven stratification of complex syndromes such as sepsis, stroke, and acute respiratory distress syndrome, demonstrating how data-driven models support early detection, personalized interventions, and actionable clinical decisions.The volume also presents system-level innovations, including AI-based forecasting for dialysis, blood supply management, and telemedicine optimization. It addresses ethical and regulatory challenges, fairness, transparency, data governance, and clinical validation, providing a practical roadmap for healthcare professionals, engineers, researchers, and policymakers. By integrating responsible, human-centered AI into precision medicine, the book illustrates clear pathways to enhance patient care, improve outcomes, and promote equitable healthcare.

  • Music and Sleep

    A Scientific Perspective
    • 1st Edition
    • Kira Vibe Jespersen + 1 more
    • English
    Music and Sleep: A Scientific Perspective presents a comprehensive discussion on the topic of music and sleep. The book brings these disciplines together, providing a solid background, recent developments, and a deeper understanding of their synthesis. Of special interest are technical advances that have made sleep recordings, music manipulation, and sleep stimulation more accessible in recent years. Notably, sleep disturbances are an increasing problem in society, highlighting the importance of developing low-risk and cost-effective treatments. Healthcare professionals looking to integrate novel information on music and sleep to increase their patients' wellbeing need look no further than this book.Music is widely used as sleep aid, but the exact neural mechanisms of the sleep-enhancing function of music are not fully clear. New research output includes exciting breakthroughs, hypotheses, and discoveries in both of these areas. However, since research fields on the neuroscientific mechanisms of music and those of sleep have not traditionally overlapped, this book fills in the gaps.

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