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Books in Life sciences

  • Microbial Enzymes

    Classification, Biochemistry, Production and Applications
    • 1st Edition
    • Abdel Moneim Elhadi Sulieman
    • English
    Microbial Enzymes: Classification, Biochemistry, Production and Applications explores the multifaceted roles of microbial enzymes, emphasizing their stability, ease of handling, and manipulation, all of which make them invaluable in various industrial processes. With 25 in-depth chapters, the book delves into the biochemistry of enzymes, their various sources, and their importance in biotechnology. It covers modern techniques for microbial enzyme detection and determination, methods of enzyme immobilization, and the application of microbial enzymes in industries such as food, medicine, pharmaceuticals, and textiles. Special sections discuss the biosynthesis of metal nanoparticles by microbial enzymes and the role of microbial toxins in different sectors. The book's chapters are organized in a way that provides detailed insights into the classification of enzymes, the mechanisms of microbial enzymes, and their industrial importance. Topics include bacterial, fungal, and algal enzymes, their applications, and the latest advancements in enzyme technology. Other sections address the challenge of antibiotic resistance and explores innovative methods for enzyme production and molecular engineering.

  • Precision Medicine in Neurodegenerative Diseases: From Research to Clinical Practice

    • 1st Edition
    • Volume 297
    • English
    Precision Medicine in Neurodegenerative Diseases: From Research to Clinical Practice, Volume 298 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on timely topics such as Introduction to Precision Medicine in Neurodegeneration, Genetic and Epigenetic Drivers of Neurodegenerative Disorders, Biomarkers: From Early Detection to Treatment Personalization, Multi-Omics Integration in Disease Research, AI and Emerging Technologies for Diagnosis, Advanced Neuroimaging in Precision Neurology, and much more.Additional chapters cover Precision Therapeutics for Alzheimer's Diseases, Personalized Management of Parkinson's Diseases, Pharmacogenomics and CRISPR-Based Therapies, Patient-Centric Care and Digital Health Tools, and Global Case Studies and Collaborative Frameworks, Future Horizons: Innovation, Aging, and Equity.

  • Neurobiology of Aging

    Exploring Cognitive Decline and Neurodegeneration
    • 1st Edition
    • Sachchida Nand Rai
    • English
    Neurobiology of Aging: Exploring Cognitive Decline and Neurodegeneration is a comprehensive reference exploring the complexities of the aging brain. This book examines the intricate processes driving cognitive decline and neurodegeneration. From the gradual loss of neurons and synapses to the formation of protein aggregates characteristic of Alzheimer's disease, each chapter reviews key aspects of brain aging. Chapters dissect the mechanisms driving neuronal loss, synaptic dysfunction, and protein misfolding, shedding light on the intricate interplay of oxidative stress, inflammation, and mitochondrial dysfunction. This book also navigates through strategies for healthy brain aging, from the impact of diet and exercise to the role of cognitive stimulation.

  • Encyclopedia of Reproduction

    • 3rd Edition
    • Michael K. Skinner
    • English
    The Encyclopedia of Reproduction, Third Edition, Six Volume Set comprehensively reviews biology and abnormalities, also covering the most common diseases in humans, such as prostate and breast cancer, as well as normal developmental biology, including embryogenesis, gestation, birth and puberty. Each of the 575 chapters provides a comprehensive overview by leaders in their respective fields that is ideal for advanced undergraduate students, research professionals, and clinicians. Chapters explore the latest advances in cloning, stem cells, endocrinology, clinical reproductive medicine, and genomics.As reproductive health is a fundamental component of an individual’s overall health status and a central determinant of quality of life, this 6-volume set provides the most extensive and authoritative reference within the field.

  • Plant-Based Proteins Processing

    Emerging Trends and Applications
    • 1st Edition
    • C.K. Sunil + 2 more
    • English
    Plant-Based Proteins Processing: Emerging Trends and Applications covers sources, extraction, properties, bioavailability, modification, applications, and marketing opportunities, in addition to the conventional and emerging technologies applied for obtaining plant-based proteins. This book consists of five sections, starting with Section A which includes chapters on overview, sources, digestibility and bioavailability, nutritional properties, and food byproducts as a source of protein. Section B covers the extraction of plant-based proteins, which has chapters on the chemical, enzyme, and novel techniques for extraction of plant proteins. Section C chapters focus on the modification of the plant protein, including all the modification methods (Thermal, Non-thermal, Biological, and Chemical methods) and their effects on the protein. Section D includes the applications of the proteins, and the last Section, E, covers the market, challenges, and future opportunities for plant-based proteins. Plant-Based Proteins Processing is a complete guide for students, researchers, professionals, consumers, food manufacturers, and others who are engaged in plant-based protein production.

  • Methods for the Study of Microbial Biofilms

    Current Trends and Recent Advancements
    • 1st Edition
    • Abhishek Guldhe + 2 more
    • English
    Methods for the study of microbial biofilms: Current Trends and Recent Advancements provides a detailed overview of the latest techniques for the study of biofilms. The book explores a wide range of methods for the characterization and study of cells within biofilms, including microscopy techniques, genomic approaches, transcriptomics, proteomic and proteogenomic tools. Computational and mathematical modelling are also covered.Chapters investigate the physiology of biofilm cells, gene expression pathways related to the formation, maturation and dispersion of biofilms, and molecular factors governing the biofilm formation and development, providing an overview of techniques that can be used at the cellular and molecular level. This book provides a broad overview of the biofilm field, along with the range of techniques that can be used to study and better understand them.

  • Protein Misfolding Diseases

    • 1st Edition
    • Volume 148
    • English
    Protein Misfolding Diseases, delves into the intricate molecular mechanisms behind a class of devastating disorders caused by abnormal protein folding. This comprehensive book explores interesting and updated topics, including Protein misfolding in hemophilia, Characterizing Protein Misfolding: Inside and Out, Heat Shock proteins (HSPs) as chaperones for Oncogenesis, Protein Misfolding and Cancer: Molecular Insights and Future Perspectives, Proteostasis and Pathogenesis: Unraveling the Complexity of Protein Misfolding Disorders, Small molecule inhibitors targeting α-synuclein aggregation: Progress and future outlook, and much more.Additional sections cover Chaperone Machinery in Neurodegeneration: A Spotlight on Protein Misfolding Diseases and Calpain- mediated proteolytic cleavage.

  • Chemoresistance in Glioblastoma

    Understanding and Management
    • 1st Edition
    • Dileep Kumar + 1 more
    • English
    Chemoresistance in Glioblastoma: Understanding and Management gives clear insights into the detailed characteristic aspects of glioblastoma disease and the different therapeutic targets that are employed in reducing resistance to chemotherapeutic agents. The book delves deep into the root causes of multidrug resistance and the quest for novel molecular targets among growth factors, receptors, signal transduction proteins, microRNAs, transcription factors, proto-oncogenes, and tumor suppressor genes. In addition, it gives insights on the pathological and molecular features of glioblastoma and the role of cancer stem cells in the resistance to chemo and immunotherapy.While designed as a comprehensive guide, the book also serves as a valuable reference for professionals seeking to deepen their understanding, refine their skills, and explore new avenues within chemoresistance.

  • Introduction to Contemporary Philosophy of Medicine

    • 1st Edition
    • James A. Marcum
    • English
    Introduction to Contemporary Philosophy of Medicine explores philosophical approaches to the nature of medicine, ranging from the Analytic Philosophy of Medicine to Feminist and Gender Medicine. Digital, Complementary, and Alternative Medicines are also discussed, with each diverse approach informed by different ontological and epistemological concepts, such as causation, disease, and health, which are introduced and discussed in detail. This is a key guide for students and other healthcare professionals interested in philosophical issues in contemporary medicine.Contemporar... philosophy of medicine is certainly a growing discipline in the 21st century, with substantial literature. But the discipline has no overarching paradigm that reflects consensus. Rather, contemporary philosophy of medicine is diverse, with various approaches not only to the problems facing contemporary medicine, but also how best to address and potentially resolve them. This book explores these concepts and their diverse approaches.

  • Basics in Amino Acid Metabolism in Humans in Health and Disease

    • 1st Edition
    • Milan Holeček
    • English
    Basics in Amino Acid Metabolism in Humans in Health and Disease summarizes the significance of amino acids and their metabolism. This book provides a single source of information bringing together a wide variety of research on the subject, explaining the rationality and risks of using some amino acids as dietary supplements. The first chapters describe amino acids' structure, classification, and transport across cell membranes and their role in protein synthesis, gluconeogenesis, and ketogenesis. The central part of the book is focused on the role of individual amino acids in the synthesis of various biologically essential substances and their metabolism in acquired and hereditary diseases. The following chapters are dedicated to the role of particular organs, such as the small intestine, intestinal microbiota, liver, muscle, kidneys, brain, adipose tissue, and lungs. The next sections are focused on amino acid metabolism under various physiological (food intake, starvation, exercise, and elderly) and pathological (systemic inflammatory response, cirrhosis, diabetes, chronic renal insufficiency, and cancer) conditions. The last chapter summarizes the benefits and potential adverse effects of increased intake of individual amino acids. The author, Professor Milan Holeček, has been studying and researching in the area for over 40+ years. "Basics in Amino Acid Metabolism in Humans in Health and Disease" is written for healthcare professionals, primarily nutritionists, specialists in intensive metabolic care, clinical nutrition, diabetology, hepatology, gerontology, gastroenterology, nephrology, and oncology.

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