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Elsevier

Books in Life sciences

  • Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation

    Models in Discovery and Translation
    • 2nd Edition
    • Gerard Socie + 2 more
    • English
    Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation: Models in Discovery and Translation, Second Edition once again provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemi... effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes, and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future. The second edition is fully revised and includes new chapters on microbiome, metabolism, kinase targets, micro-RNA and mRNA regulatory mechanisms, signaling pathways in GVHD, innate lymphoid system development, recovery and function in GVHD, genetically engineered T-cell therapies, immune system engagers for GVHD and graft-versus-tumor, and hematopoietic cell transplant for tolerance induction in solid organ grafts.

  • Cognitive Prosthethics

    • 1st Edition
    • Maxime Derian
    • English
    Computerized machines can be found in many forms and all around us – in our pockets, and even sometimes in our body. For many of us, they are now essential elements of everyday life. When it comes to smartphones, connected objects, medical digital devices and e-health, these digital tools have proliferated in our environment, continually transforming our modes of social organization. They act as prostheses and orthotics that “enhance” our cognitive capacities and influence our inherent behaviors. Are digital tools that perpetually envelop the body and the spirit able to overwhelm the social order? Could our cognitive prosthetics lead to permanent, radical change to our society, which could become similar to a hive? This book explores this reflection, which is at the center of social research on digital tools.

  • Microfluidics in Cell Biology Part C: Microfluidics for Cellular and Subcellular Analysis

    • 1st Edition
    • Volume 148
    • English
    Microfluidics in Cell Biology Part C, Volume 148, a new release in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are three sections on microfluidics in various multi-cellular models, including microfluidics in cell monolayers/spheroids... microfluidics in organ on chips, and microfluidics in model organisms. Specific chapters discuss collective migration in microtubes, leukocyte adhesion dynamics on endothelial monolayers under flow, constrained spheroid for perfusion culture, cells in droplet arrays, heart on chips, kidney on chips, liver on chips, and more.

  • Imaging in Movement Disorders: Imaging Applications in Non-Parkinsonian and Other Movement Disorders

    • 1st Edition
    • Volume 143
    • Marios Politis
    • English
    Imaging in Movement Disorders: Imaging in Other Movement Disorders and Dementia, Volume 143 provides an up-to-date textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. The book brings together lessons learned from neuroimaging tools in the content of movement disorders, including idiopathic and sporadic forms of Parkinson’s disease, Huntington’s disease, Atypical Parkinsonism, Dystonia, Essential Tremor, and more. Specific chapters cover Neuroimaging Applications in Dystonia, Neuroimaging Applications in Essential Tremor, Neuroimaging applications in Restless Leg Syndrome, Neuroimaging Application in Tourette's Syndrome and TIC Disorders, Neuroimaging Applications in Functional Movement Disorders, and Neuroimaging Applications in Cerebellar Disorders. Addition sections cover Molecular Imaging of Parkinson's Disease Cognitive Impairment, Structural MRI in Parkinson's Disease Cognitive Impairment, Functional MRI in Parkinson's Disease Cognitive Impairment, Molecular Imaging of Dementia with Lewy Bodies, Structural and Functional MRI of Dementia with Lewy Bodies, Transcranial Sonography in Movement Disorders, Imaging transplantation in Movement Disorders, Hybrid PET-MRI Applications in Movement Disorders, amongst other topics.

  • Measuring Mental Disorders

    Psychiatry, Science and Society
    • 1st Edition
    • Philippe Le Moigne
    • English
    This book is a collective work draws on the perspective of social sciences, mobilizing perspectives from the sociology of science, the history of psychiatry, medical ethnography and public policy analysis. This initiative, which has no precedent in social sciences, is surrounded by an original, if not apparently paradoxical statement: considering that the deployment of these processes, strictly formal and depersonalized, is justified in becoming the rule in a society known as "individuals".

  • Psychedelic Neuroscience

    • 1st Edition
    • Volume 242
    • Tanya Calvey
    • English
    We are in the midst of what is being called the ‘psychedelic renaissance’ with growing interest into how psychedelics alter consciousness, brain function and brain connectivity. The acute, often profound, effects of the psychedelic experience can induce lasting improvements in mental health demonstrating that chemistry forms the basis of mystical experience, consciousness and mental wellbeing.

  • Plant Epigenetics Coming of Age for Breeding Applications

    • 1st Edition
    • Volume 88
    • English
    Epigenetics and Breeding, Volume 88, the latest release in the Advances in Botanical Research series, brings together the experiences and critical information teachers, researchers and managers must consider from both scientific and legal points-of-view as they relate to biotechnology. New chapters in this updated volume include sections on Epigenetic Mechanisms in Plants, Epigenomic Diversity and Applications to Breeding, Epigenetics in Breeding, EpiRILs: Lessons from Arabidopsis, Transposable Elements as a Tool for Plant Improvement, Epigenome Editing, Epigenetics and Grafting, Sexual and Non-sexual reproduction, Epigenetics in Cereals, and more.

  • Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy

    • 1st Edition
    • Volume 4
    • English
    Tyrosine Kinase Inhibitors as Sensitizing Agents for Chemotherapy, the fourth volume in the Cancer Sensitizing Agents for Chemotherapy Series, focuses on strategic combination therapies that involve a variety of tyrosine kinase inhibitors working together to overcome multi-drug resistance in cancer cells. The book discusses several tyrosine kinase inhibitors that have been used as sensitizing agents, such as EGFR, BCR-ABL, ALK and BRAF. In each chapter, readers will find comprehensive knowledge on the inhibitor and its action, including its biochemical, genetic, and molecular mechanisms' emphases. This book is a valuable source for oncologists, cancer researchers and those interested in applying new sensitizing agents to their research in clinical practice and in trials.

  • Neuroergonomics

    The Brain at Work and in Everyday Life
    • 1st Edition
    • Hasan Ayaz + 1 more
    • English
    Neuroergonomics: The Brain at Work and in Everyday Life details the methodologies that are useful for keeping an ideal human-machine system up-to-date, along with information on how to prevent potential overload and minimize errors. It discusses neural measures and the proper methods and technologies to maximize performance, thus providing a resource for neuroscientists who want to learn more about the technologies and real-time tools that can help them assess cognitive and motivational states of human operators and close the loop for advanced human-machine interaction. With the advent of new and improved tools that allow monitoring of brain activity in the field and better identification of neurophysiological markers that can index impending overload or fatigue, this book is a timely resource on the topic.

  • Advanced Nanomaterials for Membrane Synthesis and Its Applications

    • 1st Edition
    • Woei Jye Lau + 3 more
    • English
    Advanced Nanomaterials for Membrane Synthesis and Its Applications provides the academic and industrial communities the most up-to-date information on the latest trends in membrane nanomaterials and membrane nanotechnology used in wastewater treatment, environmental technology and energy. The rapid advances in nanomaterials and nanotechnology development over the past decade have resulted in significant growth of the membrane business for various industrial processes, particularly in nanotechnology-based membrane processes. While membrane technology is increasingly being used for liquid and gas separations, it has great potential in a variety of additional applications. As the worldwide academic community has a strong interest in advanced membrane processes, particularly membrane nanotechnology for specific separations, this book provides a timely update on the topic.

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