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Gas Bubble Dynamics in the Human Body provides a broad range of professionals, from physicians working in a clinic, hospital or hyperbaric facility, to physical scientist… Read more
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Gas Bubble Dynamics in the Human Body provides a broad range of professionals, from physicians working in a clinic, hospital or hyperbaric facility, to physical scientists trying to understand and predict the dynamics of gas bubble behavior in the body, with an interdisciplinary perspective on gas-bubble disease. Both iatrogenic and decompression-induced gas bubbles are considered. The basic medical and physiological aspects are described first, in plain language, with numerous illustrations that facilitate an intuitive grasp of the basic underlying medicine and physiology. Current issues in the field, particularly microbubbles and microparticles, and their possible role in gas-bubble disease are included. The physical and mathematical material is given at several levels of sophistication, with the "hard-core" math separated out in sections labelled "For the Math Mavens", so that the basic concepts can be grasped at a descriptive level. The field is large and multi-disciplinary, so that some of the discussion that is at a greater depth is given separately in sections labelled "In Greater Detail". Skipping these sections for whatever reason, shouldn’t materially hamper acquiring an overall appreciation of the field.
This book is intended for people who are interested in or concerned about gas-bubble disease (decompression sickness and gas embolism) in humans. This covers a broad range of potential readers, from those with an academic interest in the math, physics and chemistry aspects, to those involved in treating or causing gas bubbles in the body. This includes researchers, students and graduates, and those with a PhD in biochemistry, biophysics, molecular biology, computational chemistry, physiology, and applied mathematics. It also applies to physicians and healthcare professionals, including hyperbaric and diving medicine, anesthesiology and many other medical and surgical fields that can cause entry of gas bubbles into patients. It will also be of interest to experts in professional diving. The analyses in the book range from clinical to mathematical. Material from each end of spectrum will enable those at the other end to appreciate the complexity of the entire spectrum. While there may be more math or more clinical content than purists from one side or another might prefer, understanding gas-bubble disease requires an interdisciplinary approach, and there is ample specialized content in the book to interest the full spectrum of those interested in gas-bubble disease.
1. Bubbles in the body: The not so good, the bad and the ugly2. Driving force for gas bubble growth and dissolution3. Rates of gas bubble growth and dissolution in simple liquids4. Estimating the radii and lifetimes of small gas bubbles suspended in simple liquids5. AGEs in scuba diving and in DCS-like problems in breath-hold diving6. Gas bubbles in soft tissue-like solids7. The evils that bubbles do8. Compartmental decompression models and DCS risk estimation9. Treating teh evils that bubbles do10. Merging medicine and Mmath: Gas bubble dynamics in the treatment of gas-bubble disease
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