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Elsevier

Books in Life sciences

  • Neurobiology of Depression

    Road to Novel Therapeutics
    • 1st Edition
    • Joao L. de Quevedo + 2 more
    • English
    Neurobiology of Depression: Road to Novel Therapeutics synthesizes the basic neurobiology of major depressive disorder with discussions on the most recent advances in research, including the interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the development of novel optogenetic approaches that are changing research perspectives and revolutionizing research into depression. These basic foundational understandings on the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research are combined in this book to aid advanced students and researchers in their understanding of MDD. Depression is one of the most common mental-health disorders caused by a variety of genetic, biological, environmental and psychological factors. Major depressive disorder (MDD) is typically treated with first-line antidepressant agents that primarily target monoamine neurotransmission. However, only approximately one-third of patients with MDD achieve remission following a trial with such an antidepressant. Furthermore, MDD is a heterogeneous phenotype, and new frameworks, such as the NIMH Research Domain Criteria (RDoC) may provide a more accurate, biologically based comprehension of the symptomatic heterogeneity of this devastating illness.

  • Microbiome and Metabolome in Diagnosis, Therapy, and other Strategic Applications

    • 1st Edition
    • Joel Faintuch + 1 more
    • English
    Microbiome and Metabolome in Diagnosis, Therapy, and Other Strategic Applications is the first book to simultaneously cover the microbiome and the metabolome in relevant clinical conditions. In a pioneering fashion, it addresses not only the classic intestinal environment, but also the oral, gastric, lung, skin and vaginal microbiome that is in line with the latest investigations. Nonbacterial microbiomes, such as fungi and viruses are not overlooked, and the plasma microbiome is also discussed. As plasma, brain, placenta, tumor cells, and other sterile fluids and tissues, are increasingly recognized to potentially host a microbiome, albeit a limited one, this is a timely resource. The book's editors were fortunate to have the input of renowned collaborators from nearly all continents. This is truly an international effort that brings the latest in the field to students and professionals alike.

  • Atlas of the Morphology of the Human Cerebral Cortex on the Average MNI Brain

    • 1st Edition
    • Michael Petrides
    • English
    Atlas of the Morphology of the Human Cerebral Cortex on the Average MNI Brain provides a comprehensive identification of the sulci and gyri of the human brain on a series of coronal sections of the average MNI brain and identifies the likely location of the cytoarchitectonic areas of the cerebral cortex. Presentation in MNI Stereotaxic Space enables the atlas to serve as a useful working tool for structural/functiona... neuroimagers attempting to identify the sulcus or gyrus and the likely cytoarchitectonic area within which a functional activation or a structural change has occurred. A brief introductory section discusses the history and current state of studies of the sulcal and gyral morphology and cytoarchitecture of the human cerebral cortex.

  • Production and Management of Beverages

    Volume 1. The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Production and Management of Beverages, Volume One in the Science of Beverages series, introduces the broad world of beverage science, providing an overview of the emerging trends in the industry and the potential solutions to challenges such as sustainability and waste. Fundamental information on production and processing technologies, safety, quality control, and nutrition are covered for a wide range of beverage types, including both alcoholic and nonalcoholic beverages, fermented beverages, cocoa and other powder based beverages and more. This is an essential resource for food scientists, technologists, chemists, engineers, microbiologists and students entering into this field.

  • Processing and Sustainability of Beverages

    Volume 2: The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Processing and Sustainability of Beverages, Volume Two in the Science of Beverages series, is a general reference of the current and future actions for a sustainable beverage industry. This resource takes a unique approach, combining processing with sustainability. Topics of note include waste treatment and management, environmental analysis for a sustainable beverage industry, and modern technologies for beverage processing to reduce contaminants and increase the quality. This book is essential to scientists, researchers and technologists in the beverages field, covering both alcoholic and nonalcoholic beverages.

  • The Eradication of Dracunculiasis (Guinea Worm Disease) in Nigeria

    An Eyewitness Account
    • 1st Edition
    • Luke Ekundayo Edungbola
    • English
    The Eradication of Dracunculiasis (Guinea Worm Disease) in Nigeria: An Eyewitness Account documents the process used to eradicate one of the most neglected public health challenges in Nigeria. The book's chapters discuss the need for well developed and implemented eradication strategies, the availability of human and material resources, and the collaboration that is necessary with international partners. In addition, sections highlight challenges, the benefits of perseverance, and the international support and multi-sectoral approach that is needed to tackle national problems. It demonstrates that other endemic tropical diseases and conditions can be eliminated or controlled if a similar approach is adopted.

  • Bioactive Compounds

    Health Benefits and Potential Applications
    • 1st Edition
    • Maira Rubi Segura Campos
    • English
    Bioactive Compounds: Health Benefits and Potential Applications provides information about different bioactive compounds including their sources, biological effects, health benefits and, potential applications which could contribute as alternatives in the prevention or treatment of multifactorial diseases for vulnerable population groups. Going beyond the basics to include discussion of bioaccessibility and the legislative aspects of marketing of bioactive compounds as nutraceuticals or food supplements, this book presents insights from a global perspective. Written for researchers, professors and graduate students, this book is sure to be a welcomed reference for all who work in food chemistry, new product development and nutritional science.

  • Imagining the Brain: Episodes in the History of Brain Research

    • 1st Edition
    • Volume 243
    • Chiara Ambrosio + 1 more
    • English
    Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Basic Fundamentals of Drug Delivery

    • 1st Edition
    • English
    Basic Fundamentals of Drug Delivery covers the fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to transform a drug candidate or new chemical entity into a final administrable drug delivery system. The book also covers various approaches involved in optimizing the therapeutic performance of a biomolecule while designing its appropriate advanced formulation.

  • The Chick Brain in Stereotaxic Coordinates and Alternate Stains

    Featuring Neuromeric Divisions and Mammalian Homologies
    • 2nd Edition
    • Luis Puelles + 4 more
    • English
    This atlas – and its accompanying text - is the most comprehensive work on avian neuroanatomy available so far. It identifies more than 900 hundred structures (versus ca. 250 in previous avian atlases), 180 of them for the first time. It correlates avian and mammalian neuroanatomy on the basis of homologies and applies mammalian terms to homologous avian structures. This is the first atlas that represents the fundamental histogenetic domains of the vertebrate neuroaxis on the basis of sound fate-mapping and gene expression data. This results in a substantial increase in accuracy of delineations. Developmental molecular biologists will find it easier to extrapolate early neural tube patterns into mature structures. The modern trend to shift avian neuroanatomical nomenclature toward mammalian terminology by reference to postulated homologies has been expanded to the entire brain, but is not yet complete. This creates a new standard for comparative cross-reference, which can also be applied to reptilian-mammalian comparisons.

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