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Books in Life sciences

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    • Membranes in Pulmonary Vascular Disease

      • 1st Edition
      • Volume 82
      • October 22, 2018
      • English
      • Hardback
        9 7 8 0 1 2 8 1 5 8 0 6 7
      • eBook
        9 7 8 0 1 2 8 1 5 8 0 7 4
      Membranes in Pulmonary Vascular Disease, Volume 82, the latest release in the Current Topics in Membranes series, highlights new advances in the field, with this new volume presenting interesting chapters from recognized experts on topics such as Sphingolipids in Vascular Lung Disease, Endothelial Glycocalyx, Cholesterol Regulation of Endothelial Cell Calcium Homeostasis in Pulmonary Hypertension, Mechanosensitive Channels and Gap Junction Channels in EC, Endothelial Protrusions in Junctional Integrity and Barrier Function, Cortical Actin Dynamics in Endothelial Permeability, Endothelial Microparticles and Exosomes, Store Operated TRP Channels and Endothelial Responses, and Caveolin and Endothelial NO signaling.

    • Novel Designs of Early Phase Trials for Cancer Therapeutics

      • 1st Edition
      • May 22, 2018
      • Shivaani Kummar + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 2 5 1 2 0
      • eBook
        9 7 8 0 1 2 8 1 2 5 7 0 0
      Novel Designs of Early Phase Trials for Cancer Therapeutics provides a comprehensive review by leaders in the field of the process of drug development, the integration of molecular profiling, the changes in early phase trial designs, and endpoints to optimally develop a new generation of cancer therapeutics. The book discusses topics such as statistical perspectives on cohort expansions, the role and application of molecular profiling and how to integrate biomarkers in early phase trials. Additionally, it discusses how to incorporate patient reported outcomes in phase one trials. This book is a valuable resource for medical oncologists, basic and translational biomedical scientists, and trainees in oncology and pharmacology who are interested in learning how to improve their research by using early phase trials.

    • Advances in Cancer Research

      • 1st Edition
      • Volume 137
      • January 24, 2018
      • English
      • Hardback
        9 7 8 0 1 2 8 1 5 1 2 3 5
      • eBook
        9 7 8 0 1 2 8 1 5 1 2 4 2
      Advances in Cancer Research, Volume 137, the latest release in this ongoing, well-regarded serial provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents original reviews on research bridging oncology and gene expression, with this volume covering unconventional approaches to modulating the immunogenicity of tumor cells, tumor dormancy and immunoediting, the emerging role of anti-apoptotic Bcl-2 family proteins in chemoresistance, Beclin-1 and autophagy, MDA-7/IL-24, and nanotechnology and medicine.

    • Forensic Toxicology

      • 1st Edition
      • January 2, 2018
      • Max M. Houck
      • English
      • Hardback
        9 7 8 0 1 2 8 0 0 7 4 6 4
      • eBook
        9 7 8 0 1 2 8 0 0 8 1 8 8
      Forensic Toxicology, the latest release in the Advanced Forensic Science Series that grew out of recommendations from the 2009 NAS Report, Strengthening Forensic Science: A Path Forward will serve as a graduate level text for those studying and teaching forensic toxicology. It is also an excellent reference for the forensic practitioner’s library or for use in their casework. Coverage includes a wide variety of methods used, along with pharmacology and drugs and professional issues they may encounter. Edited by a world-renowned, leading forensic expert, this updated edition is a long overdue solution for the forensic science community.

    • Smart Wheelchairs and Brain-computer Interfaces

      • 1st Edition
      • May 29, 2018
      • Pablo Diez
      • English
      • Paperback
        9 7 8 0 1 2 8 1 2 8 9 2 3
      • eBook
        9 7 8 0 1 2 8 1 2 8 9 3 0
      Smart Wheelchairs and Brain-Computer Interfaces: Mobile Assistive Technologies combines the fields of neuroscience, rehabilitation and robotics via contributions from experts in their field to help readers develop new mobile assistive technologies. It provides information on robotics, control algorithm design for mobile robotics systems, ultrasonic and laser sensors for measurement and trajectory planning, and is ideal for researchers in BCI. A full view of this new field is presented, giving readers the current research in the field of smart wheelchairs, potential control mechanisms and human interfaces that covers mobility, particularly powered mobility, smart wheelchairs, particularly sensors, control mechanisms, and human interfaces.

    • Thyroid Hormone

      • 1st Edition
      • Volume 106
      • January 18, 2018
      • English
      • Hardback
        9 7 8 0 1 2 8 1 4 1 1 6 8
      • eBook
        9 7 8 0 1 2 8 1 4 1 1 7 5
      Thyroid hormone, Volume 106, the latest release in the Vitamins and Hormones series first published in 1943 provides up-to-date information on crystal structures and basic structural studies on neurotrophins and their receptors, neurotrophin functions and the biological actions of neurotrophins related to clinical conditions and disease. This new release focuses on timely topics, including the Nuclear Import and Export of the Thyroid Hormone Receptor, the Thyroid hormone and the white matter of the central nervous system: from development to repair, Thyroid hormone and astrocyte differentiation, and the Molecular Basis of Nongenomic Actions of Thyroid Hormone, amongst other topics.

    • Integrated Analytical Approaches for Pesticide Management

      • 1st Edition
      • July 17, 2018
      • Britt Maestroni + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 6 1 5 5 5
      • eBook
        9 7 8 0 1 2 8 1 6 1 5 6 2
      Integrated Analytical Approaches for Pesticide Management provides proven laboratory practices/examples and methods necessary to control pesticides in food and water in various environments. The book presents insights into good laboratory practices and examples of methods used in individual specialist laboratories, thus enabling stakeholders in the agri-food industry to appreciate the importance of proven, reliable data and the associated quality assurance approaches for end product testing for toxic levels of contaminant residues in food. The book is written in a rigorous, but simple, way to make sure that a broad range of readers can appreciate its technical content. The book's practical nature and generic guidelines distinguish it from others in the marketplace.

    • Management of High Altitude Pathophysiology

      • 1st Edition
      • July 19, 2018
      • Kshipra Misra + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 3 9 9 9 8
      • eBook
        9 7 8 0 1 2 8 1 4 0 0 0 0
      Management of High Altitude Pathophysiology presents a comprehensive overview on the various therapeutic practices and ongoing research relating to the development of more potent and novel formulations for managing high altitude pathophysiology. It provides a detailed application of both herbal and non-herbal therapeutic agents, including their nanoformulations. This important reference provides benefits to the medical and herbal scientific communities, doctors treating patients with high altitude complications, individuals travelling to high altitudes for recreation or work, and scientists working on future drug development.

    • Microbial Diversity in the Genomic Era

      • 1st Edition
      • September 20, 2018
      • Surajit Das + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 4 8 4 9 5
      • eBook
        9 7 8 0 1 2 8 1 4 8 5 0 1
      Microbial Diversity in the Genomic Era presents insights on the techniques used for microbial taxonomy and phylogeny, along with their applications and respective pros and cons. Though many advanced techniques for the identification of any unknown bacterium are available in the genomics era, a far fewer number of the total microbial species have been discovered and identified to date. The assessment of microbial taxonomy and biosystematics techniques discovered and practiced in the current genomics era with suitable recommendations is the prime focus of this book.

    • Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination

      • 1st Edition
      • Volume 600
      • February 17, 2018
      • English
      • Hardback
        9 7 8 0 1 2 8 1 4 4 2 9 9
      • eBook
        9 7 8 0 1 2 8 1 4 4 3 0 5
      Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination, Volume 600, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Homologous genetic recombination remains the most enigmatic process in DNA metabolism. The molecular machines of recombination preserve the integrity of the genetic material in all organisms and generate genetic diversity in evolution. The same molecular machines that support genetic integrity by orchestrating accurate repair of the most deleterious DNA lesions, however, also promote survival of cancerous cells and emergence of radiation and chemotherapy resistance. This two-volume set offers a comprehensive set of cutting edge methods to study various aspects of homologous recombination and cellular processes that utilize the enzymatic machinery of recombination The chapters are written by the leading researches and cover a broad range of topics from the basic molecular mechanisms of recombinational proteins and enzymes to emerging cellular techniques and drug discovery efforts.

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