Books in Life sciences

Handbook of Modern Pharmaceutical Analysis

1st Edition
Volume 3
July 26, 2001
Satinder Ahuja + 1 more
English
eBook
9 7 8 0 0 8 0 4 8 8 9 2 9

This book describes the role modern pharmaceutical analysis plays in the development of new drugs. Detailed information is provided as to how the quality of drug products is assured from the point of discovery until the patient uses the drug. Coverage includes state-of-the-art topics such as analytics for combinatorial chemistry and high-throughput screening, formulation development, stability studies, international regulatory aspects and documentation, and future technologies that are likely to impact the field. Emphasis is placed on current, easy-to-follow methods that readers can apply in their laboratories.No book has effectively replaced the very popular text, Pharmaceutical Analysis, that was edited in the 1960s by Tak Higuchi. This book will fill that gap with an up-to-date treatment that is both handy and authoritative.

Drug-Nucleic Acid Interactions

1st Edition
Volume 340
July 26, 2001
Jonathan B. Chaires + 1 more
English
eBook
9 7 8 0 0 8 0 4 9 6 9 0 0

This volume consolidates the key methods for studying ligand-nucleic acid interactions into a convenient source. Techniques that are examined range from biophysical and chemical approaches to methods rooted in molecular and cell biology.

Radio Tracking and Animal Populations

1st Edition
July 23, 2001
Joshua Millspaugh + 1 more
English
eBook
9 7 8 0 0 8 0 5 4 0 2 2 1

Radio Tracking and Animal Populations is a succinct synthesis of emerging technologies and their applications to the empirical and theoretical problems of population assessment. The book is divided into sections designed to encompass the various aspects of animal ecology that may be evaluated using radiotelemetry technology - experimental design, equipment and technology, animal movement, resource selection, and demographics. Wildlife biologists at the leading edge of new developments in the technology and its application have joined forces.

New Foundation of Biology

1st Edition
Volume 1
July 19, 2001
I. Berczi + 1 more
English
eBook
9 7 8 0 0 8 0 5 3 7 5 1 1

A new scientific discipline, acknowledged 65 years after its discovery, was the focus of the first Conference on Neuroimmune Biology in Canada. The papers presented at the conference, and in this volume, are dedicated to Dr. Hans Selye who is recognized as discovering the existence of a hypothalamic-pituita... axis. This axis plays an important role in the adaptation of higher animals and man to various physical, chemical, biological and emotional challenges.The conference and participants also honored Dr. Andor Szentivanyi whose opening paper, "Studies on the hypothalamic regulation of histamine synthesis", is contained in the introduction to this book. Dr. Szentivanyi has dedicated his long research career to the clarification of the role of the central nervous system in immune and inflammatory reactions, and his experimental results are presented here.With an ultimate goal to achieve a more thorough understanding of higher organisms in their entire complexity, this book, the first in the series http://serval.elsevi... Biology presents a coordinated and integrated view of the growing body of knowledge rapidly accumulating in this area.

Protein Adaptations and Signal Transduction

1st Edition
Volume 2
July 19, 2001
K.B. Storey + 1 more
English
eBook
9 7 8 0 0 8 0 5 3 9 9 6 6

This volume of Cell and Molecular Responses to Stress has two broad themes: an examination of selected protein adaptations that support stress tolerance and an analysis of signal transduction systems, those critical links between the perception of stress and the activation of the coordinated metabolic responses that ensure survival. Several chapters deal with adaptive responses to environmental cold temperature and highlight novel advances in mammalian hibernation, low temperature enzyme function, cold-shock and antifreeze proteins, and freezing survival. Other chapters stretch out to explore biochemical responses to diverse stresses including water stress, mechanical stress, nutrient availability, oxygen limitation and oxidative stress. The integral roles of protein kinases, transcription factors, oxygen free radicals, and oxygen-sensitive ion channels in the detection and mediation of stress responses are explored. The multiplicity of responses is emphasized and shows us the vast potential of cells and organisms to respond to innumerable stresses, great and small, and the regulatory principles and mechanisms that are used to allow life to adapt and endure in every environment on Earth.Featuring: A discussion of new advances in understanding protein adaptations that support organismal survival of stress. State-of-the-art analysis of key components of cellular signal transduction pathways including protein kinases and calcium and the control, integration and action of signal transduction pathways in response to stresses including mechanical stress, nutrient availability, oxidative stress.

The T Cell Receptor FactsBook

1st Edition
July 13, 2001
Marie-Paule Lefranc + 1 more
English
eBook
9 7 8 0 0 8 0 5 4 2 6 4 5

The T Cell Receptor FactsBook contains entries on all the 176 functional variable, diversity, joining, and constant regions of the human T cell receptor, including alpha, beta, gamma, and delta loci. Introductory chapters summarize information of T cell receptor chain synthesis, chromosomal location, and an overview of the human T cell receptor loci.

Auditing in the Food Industry

1st Edition
July 12, 2001
M Dillon + 1 more
English
Hardback
9 7 8 1 8 5 5 7 3 4 5 0 0
eBook
9 7 8 1 8 5 5 7 3 6 1 7 7

The food industry faces an unprecedented level of scrutiny. Consumers are not only concerned with the safety and quality of food products but also the way in which they are produced. At the same time the food industry has developed new ways of assuring appropriate standards for its products and their methods of production, developing systems such as TQM and HACCP to identify and manage key steps in production. These new methods require new skills in auditing. Auditing in the food industry provides an authoritative guide to the range of standards and the auditing skills they demand.Part one sets the scene with an introductory chapter reviewing developments in standards affecting the food industry. There then follows chapters on how retailers audit their suppliers and how governments have moved from a traditional inspection role to one of 'regulatory verification' with its emphasis on auditing the robustness of a business's own systems for managing safety and quality.Part two examines the key aspects of safety and quality. A first chapter reviews the ways retailers assess supplier HACCP systems. There is then a chapter reviewing TQM systems that provides a context for a discussion of auditing techniques for HACCP-based quality systems. A final chapter looks at standards governing the analytical methods used in safety and quality control.Part three considers newer standards that are becoming increasingly important in the food industry. There are chapters on benchmarking an organisation against others as a way of improving performance, auditing the impact of food processing operations on the environment and auditing organic food processing.Auditing in the food industry is a valuable guide to the range of standards facing the food industry and the ways it can audit, and thus improve the quality of its performance.

New Approaches for the Generation and Analysis of Microbial Typing Data

1st Edition
July 10, 2001
L. Dijkshoorn + 2 more
English
Hardback
9 7 8 0 4 4 4 5 0 7 4 0 2
eBook
9 7 8 0 0 8 0 5 3 7 4 8 1

Rapid molecular identification and typing of micro-organisms is extremely important in efforts to monitor the geographical spread of virulent, epidemic or antibiotic-resistant pathogens. It has become a mainstay of integrated hospital infection control service. In addition, numerous industrial and biotechnological applications require the study of the diversity of organisms. Conventional phenotypic identification and typing methods have long been the mainstay of microbial population and epidemiological studies, but such methods often lack adequate discrimination and their use is normally confined to the group of organisms for which they were originally devised. Molecular fingerprinting methods have flourished in recent years and many of these new methods can be applied to numerous different organisms for a variety of purposes. Standardisation of these methods is vitally important. In addition, the generation of large numbers of complex fingerprint profiles requires that a computer-assisted strategy is used for the formation and analysis of databases. The purpose of this book is to describe the best fingerprinting methods that are currently available and the computer-assisted strategies that can be used for analysis and exchange of data between laboratories.This book is dedicated to the memory of Jan Ursing (1926 - 2000), Swedish microbiologist, taxonomist and philosopher."...taxo... is on the borders of philosophy because we do not know the natural continuities and discontinuities..."

Biomedical Communications

1st Edition
July 9, 2001
Jon D. Miller
English
eBook
9 7 8 0 0 8 0 5 2 8 0 8 3

With data from the United States and Europe, Jon Miller and Linda Kimmel examine the public's understanding of and attitude toward biotechnology and biomedicine while they present methods of introducing cutting edge science to thenonscientist. Biomedical Communications illustrates how vital it is for researchers, journalists, and policy makers to clearly communicate their findings in a way that avoids general misconception or confusion. The authors explore how to acquire information about biomedical policy, discuss strategies for informing consumers, and present tactics for improving biomedical communication with the public.

The Laboratory Computer

1st Edition
July 2, 2001
John Dempster
English
Paperback
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eBook
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The Laboratory Computer: A Practical Guide for Physiologists and Neuroscientists introduces the reader to both the basic principles and the actual practice of recording physiological signals using the computer. It describes the basic operation of the computer, the types of transducers used to measure physical quantities such as temperature and pressure, how these signals are amplified and converted into digital form, and the mathematical analysis techniques that can then be applied. It is aimed at the physiologist or neuroscientist using modern computer data acquisition systems in the laboratory, providing both an understanding of how such systems work and a guide to their purchase and implementation.

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