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Books in Immunology

Elsevier's Immunology collection equips researchers with valuable insights to address the complexities of the immune system and its role in health and disease, offering original research, insightful analysis, and current theory on diagnosing, managing, and advancing treatments for allergies, asthma, and immunologic disorders.

    • Physical and Chemical Methods

      • 1st Edition
      • May 12, 2014
      • Curtis A. Williams + 1 more
      • English
      • Paperback
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      • eBook
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      Methods in Immunology: Volume II, Physical and Chemical Methods is a collection of papers dealing with electrophoresis, analytical ultracentrifugation, dialysis, ultrafiltration, cellulose ion exchangers, and chromatographic separation of macromolecules on porous gels. Some papers explain the applications of radioisotopes, optical analysis, and chemical analysis of proteins, carbohydrates, lipids, and nucleic acid. One paper describes the theory of electro-migration. Factors such as electrical charge or frictional coefficients govern the rate of migration of charged particles in an electric field. The differences found in their velocities can be used to separate substances or analyze them. Mobility is a characteristic property of molecules and can also be influenced by the composition of the medium or solution. Dialysis separates solvents too large to diffuse through a barrier from smaller solutes; ultrafiltration (reverse osmosis) forces solvent and solutes up to a certain critical size through the barrier by a high pressure on one side. The book notes that the membrane never becomes plugged in dialysis because of some opposite movement of the solvent. Another paper points out that the significance of radioactive tracers in immunochemistry employed to identify and label macromolecules functioning as antigens and antibodies. The collection can prove valuable to bio-chemists, cellular biologists, micro-biologists, developmental biologists, and scientists involved in immunological research.
    • Malaria

      • 1st Edition
      • May 12, 2014
      • Julius P. Kreier
      • English
      • Paperback
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      • eBook
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      Malaria: Volume 3, Immunology and Immunization is a collection of papers dealing with malaria parasites, the methods for measuring the immunological response to plasmodia, and the vertebrates host's immune response to plasmodia. Some papers discuss immunization against sporozoites, against the exoerythrocytic stages of malaria parasites, against asexual blood-inhabiting stages of plasmodia, as well as gamete immunization in malaria. One paper describes various separation methods to isolate malaria parasites and their constituents. Another paper discusses in detail the theory and practice of methods used in measuring antibody responses which occur during plasmodial infections, including the antibody response against sporozoites, exoerythrocytic forms, and in the different blood stages. Another paper explains the vertebrate host's immune response to plasmodial infection as a homeostatic physiological response changing along with the progression of the disease. The changes in the dynamic cellular cascade are different as the disease progresses causing death, than when these lead to recovery. Another paper enumerates the parameters which determine malarial infectiousness from one individual to another such as the time of onset, duration, intensity of the blood infections, as well as the maturity, longevity, and rate of production of gametocytes. Pharmacologists, general medical practitioners, investigators, and laboratory technicians involved in malarial research will find the collection very useful.
    • Reactions of Antibodies with Soluble Antigens

      • 1st Edition
      • May 10, 2014
      • Curtis A. Williams + 1 more
      • English
      • Paperback
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      • eBook
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      Methods in Immunology and Immunochemistry, Volume III: Reactions of Antibodies with Soluble Antigens provides information pertinent to antigen–antibody and hapten–antibody reactions in vitro, in free solution and in gels. This book presents the development of research in immunology and immunochemistry. Organized into three chapters, this volume begins with an overview of protein–antiprotein reactions. This text then discusses the inhibitory activity of protein fragments, which suggested that antigenic combining sites of proteins were limited regions of the whole antigen molecule. Other chapters consider the measurement of inhibitory activity, which is still the principal assay to characterize antigenic sites of proteins. This book discusses as well the immunological techniques prior to the development of gel-diffusion methods. The final chapter deals with fluorescence labeling techniques that provide powerful approaches for exploring the thermodynamic and kinetic parameters of antigen–antibody interactions. This book is a valuable resource for mathematicians and immunologists.
    • Bacterial Immunoglobulin–Binding Proteins

      • 1st Edition
      • May 10, 2014
      • Michael D. P. Boyle
      • English
      • Paperback
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      Bacterial Immunoglobulin-Bindi... Proteins: Applications in Immunotechnology, Volume 2 covers the state of knowledge of bacterial immunoglobulin-bindi... proteins. The book focuses on practical approaches to isolation, characterization, and use of bacterial immunoglobulin-bindi... proteins. The majority of these studies involve the type I Fc-binding protein (staphylococcal protein A) and the type III Fc-binding protein (streptococcal protein G). Physiological chemists, pediatricians, and microbiologists will find the book invaluable.
    • Agglutination, Complement, Neutralization, and Inhibition

      • 1st Edition
      • May 10, 2014
      • Curtis A. Williams + 1 more
      • English
      • Paperback
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      • eBook
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      Methods in Immunology and Immunochemistry, Volume IV: Agglutination, Complement, Neutralization, and Inhibition provides information pertinent to direct and indirect agglutination reactions. This book covers a variety of topics, including complement-fixation procedures, isolation of complement components, hemolytic intermediates, complement-related proteins, and neutralization reactions. Organized into three chapters, this volume begins with an overview of test-tube agglutinations that are preferred for blood grouping with saline agglutinins that require more than a few minutes for agglutination. This text then describes blood group antibodies that agglutinate red blood cells suspended in saline. Other chapters consider the classical pathway of complement utilization. This book discusses as well the complexity of events leading to hemolysis of erythrocytes by complement. The final chapter deals with the ability of antitoxin to neutralize diphtheria toxin and explains the quantitative relationships between antigen and antibody. This book is a valuable resource for immunologists, scientists, and research workers.
    • The Biology of B-Lactam Antibiotics

      • 1st Edition
      • May 10, 2014
      • Robert B. Morin + 1 more
      • English
      • Paperback
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      The Biology of ß-Lactam Antibiotics
    • Progress in Immunology VI

      • 1st Edition
      • May 10, 2014
      • B Cinader + 1 more
      • English
      • eBook
        9 7 8 1 4 8 3 2 7 6 1 0 6
      Progress in Immunology VI: Sixth International Congress of Immunology contains the proceedings of the Sixth International Congress of Immunology held in 1986. The papers review advances that have been made in the field of immunology and cover topics ranging from ontogeny and differentiation of B and T lymphocytes to diversification of immunoglobulins and T cell receptors. Antigen presentation and processing, the complement system, and regulation of the immune response are also discussed. Comprised of 105 chapters, this book first explores the developmental biology of the immune system by focusing on the origins of selective theories of antibody formation and the clonal selection hypothesis. Clonal selection and the problem of immunologic tolerance are also considered. Subsequent chapters deal with the structure and function of recognition structures; B cell subsets and B cell activation; T cell subsets and T cell activation; lymphokines and growth factors; and autoimmune disorders. The remaining sections are devoted to oncogenesis and tumor immunity; the response of the host to the environment; and host-graft relationship. This monograph will be of interest to immunologists and biologists.
    • Progress in Immunology

      • 1st Edition
      • May 10, 2014
      • Bernard Amos
      • English
      • eBook
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      Progress in Immunology: First International Congress of Immunology is a collection of papers and summaries of the workshops conducted at the First International Congress of Immunology. The proceedings review significant advances that have been made in the field of immunology and covers topics ranging from the structure and genetics of antibodies to lymphocyte membranes and the role of antibodies and complexes in immune tissue damage. Cell cooperation in the immune response is also examined. This volume is organized into 15 sections and begins with a discussion on the structure of immunoglobulins and results of experiments which support the domain hypothesis and the evolution of immunoglobulins by gene duplication, along with the presence of genetic markers in V regions. The reader is then introduced to expansion and contraction in the evolution of immunoglobulin gene pools; receptors for C3 on B lymphocytes and their possible role in the immune response; and subpopulations of thymus cells and thymus-derived lymphocytes. Tne remaining sections focus on effector mechahisms of cell-mediated immunity; genetic control of immune responsiveness; immune disorders in humans such as glomerulonephritis and rheumatoid arthritis; and viruses involved in immunopathology. This book is dedicated to immunologists.
    • Bacteria and Bacteriophage

      • 1st Edition
      • May 10, 2014
      • Edwin J. Atencio + 2 more
      • English
      • Paperback
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      Nucleotide Sequences 1986/1987, Volume V: Bacteria and Bacteriophage presents data that reflect the information found in GenBank Release 44.0 of August 1986. This book provides information pertinent to the unique international collaboration between two leading nucleotide sequence data libraries, one based in Europe and one in the United States. Organized into two sections, this volume begins with an overview of the sequences, some basic identifying information, and some of the biological annotations. This text then discusses the EMBL Nucleotide Sequence Data Library, an international center of fundamental research with its main focus in the fields of cell biology, molecular structures, instrumentation, and differentiation. This book discusses as well the GenBank database established in 1982 by the National Institute of General Medical Sciences (NIGMS) of the U.S National Institutes of Health (NIH). This book is a valuable resource for molecular biologists and other investigators collecting the large number of reported DNA and RNA sequences and making them available in computer-readable form.
    • Analytical Microbiology

      • 1st Edition
      • May 10, 2014
      • Frederick Kavanagh
      • English
      • Paperback
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      Analytical Microbiology, Volume II is a six-chapter work that covers the significant changes and improvements made in the theory and practice of analytical microbiology. The first chapter is devoted to the theoretical aspects of assaying of specific compounds. These topics are followed by discussions of the theoretical and practical aspects of diffusions assays, as well as the theoretical developments of photometric methods of assay, including their improvement resulting from automation. A chapter explores the assay methods for various antibiotic groups. Another chapter discusses the advances in assay technology and analytically important interrelations among the folic acid complex. The last chapter describes a simple diffusion method designed for the assay of certain amino acids in a wide variety of samples. This book will prove useful to analytical microbiologists.